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7NSL
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BU of 7nsl by Molmil
AL amyloid fibril from a lambda 1 light chain
Descriptor: Amyloid lambda1 light chain
Authors:Karimi Farsijani, S, Radamaker, L, Fandrich, M.
Deposit date:2021-03-08
Release date:2021-11-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Role of mutations and post-translational modifications in systemic AL amyloidosis studied by cryo-EM.
Nat Commun, 12, 2021
6DSO
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BU of 6dso by Molmil
Cryo-EM structure of murine AA amyloid fibril
Descriptor: Serum amyloid A-2 protein
Authors:Loerch, S, Liberta, F, Grigorieff, N, Fandrich, M, Schmidt, M.
Deposit date:2018-06-14
Release date:2019-03-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids.
Nat Commun, 10, 2019
5AEF
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BU of 5aef by Molmil
Electron cryo-microscopy of an Abeta(1-42)amyloid fibril
Descriptor: AMYLOID BETA A4 PROTEIN
Authors:Schmidt, M, Rohou, A, Lasker, K, Yadav, J.K, Schiene-Fischer, C, Fandrich, M, Grigorieff, N.
Deposit date:2015-08-29
Release date:2015-10-14
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Peptide Dimer Structure in an Abeta(1-42) Fibril Visualized with Cryo-Em
Proc.Natl.Acad.Sci.USA, 112, 2015
6SHS
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BU of 6shs by Molmil
Abeta fibril (Morphology I)
Descriptor: Amyloid-beta precursor protein
Authors:Kollmer, M, Fandrich, M.
Deposit date:2019-08-08
Release date:2019-11-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM structure and polymorphism of A beta amyloid fibrils purified from Alzheimer's brain tissue.
Nat Commun, 10, 2019
6MST
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BU of 6mst by Molmil
Cryo-EM structure of human AA amyloid fibril
Descriptor: Serum amyloid A-1 protein
Authors:Loerch, S, Rennegarbe, M, Liberta, F, Grigorieff, N, Fandrich, M, Schmidt, M.
Deposit date:2018-10-18
Release date:2019-03-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids.
Nat Commun, 10, 2019
6ZCG
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BU of 6zcg by Molmil
Amyloid fibril morphology ii (in vitro) from murine SAA1.1 protein
Descriptor: Serum amyloid A-2 protein
Authors:Bansal, A, Schmidt, M, Fandrich, M.
Deposit date:2020-06-11
Release date:2021-02-17
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils.
Nat Commun, 12, 2021
6Z1I
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BU of 6z1i by Molmil
AL amyloid fibril from a lambda 3 light chain in conformation B
Descriptor: lambda 3 light chain fragment, residues 2-116
Authors:Radamaker, L, Fandrich, M.
Deposit date:2020-05-13
Release date:2021-02-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis.
Nat Commun, 12, 2021
6Z1O
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BU of 6z1o by Molmil
AL amyloid fibril from a lambda 3 light chain in conformation A
Descriptor: lambda 3 immunoglobulin light chain fragment, residues 2-116
Authors:Radamaker, L, Fandrich, M.
Deposit date:2020-05-14
Release date:2021-02-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis.
Nat Commun, 12, 2021
3TPK
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BU of 3tpk by Molmil
Crystal structure of the oligomer-specific KW1 antibody fragment
Descriptor: 1,2-ETHANEDIOL, BENZAMIDINE, Immunoglobulin heavy chain antibody variable domain KW1
Authors:Parthier, C, Morgado, I, Stubbs, M.T, Fandrich, M.
Deposit date:2011-09-08
Release date:2012-07-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Molecular basis of beta-amyloid oligomer recognition with a conformational antibody fragment.
Proc.Natl.Acad.Sci.USA, 109, 2012
7OVT
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BU of 7ovt by Molmil
major seeded in vitro fibril morphology from murine SAA1.1 protein
Descriptor: Serum amyloid A-2 protein
Authors:Heerde, T, Schmidt, M, Faendrich, M.
Deposit date:2021-06-15
Release date:2022-02-02
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding.
Nat Commun, 13, 2022
5L6Q
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BU of 5l6q by Molmil
Refolded AL protein from cardiac amyloidosis
Descriptor: CARBONATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Annamalai, K, Liberta, F, Vielberg, M.-T, Lilie, H, Guehrs, K.-H, Schierhorn, A, Koehler, R, Schmidt, A, Haupt, C, Hegenbart, O, Schoenland, S, Groll, M, Faendrich, M.
Deposit date:2016-05-31
Release date:2017-05-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo.
Angew. Chem. Int. Ed. Engl., 56, 2017
8B3A
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BU of 8b3a by Molmil
catalytic amyloid fibril formed by Ac-LHLHLRL-amide
Descriptor: ACE-LEU-HIS-LEU-HIS-LEU-ARG-LEU-NH2
Authors:Heerde, T, Schmidt, M, Faendrich, M.
Deposit date:2022-09-16
Release date:2023-04-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of a catalytic amyloid fibril.
Sci Rep, 13, 2023
3LN9
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BU of 3ln9 by Molmil
Crystal structure of the fibril-specific B10 antibody fragment
Descriptor: CITRATE ANION, GLYCEROL, Immunoglobulin heavy chain antibody variable domain B10, ...
Authors:Parthier, C, Morgado, I, Stubbs, M.T, Faendrich, M.
Deposit date:2010-02-02
Release date:2010-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Amyloid Fibril Recognition with the Conformational B10 Antibody Fragment Depends on Electrostatic Interactions.
J.Mol.Biol., 2010
8QX9
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BU of 8qx9 by Molmil
TDP-43 amyloid fibrils: Morphology-1a
Descriptor: TAR DNA-binding protein 43
Authors:Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M.
Deposit date:2023-10-24
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Nat Commun, 15, 2024
8QXA
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BU of 8qxa by Molmil
TDP-43 amyloid fibrils: Morphology-1b
Descriptor: TAR DNA-binding protein 43
Authors:Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M.
Deposit date:2023-10-24
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Nat Commun, 15, 2024
8QXB
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BU of 8qxb by Molmil
TDP-43 amyloid fibrils: Morphology-2
Descriptor: TAR DNA-binding protein 43
Authors:Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M.
Deposit date:2023-10-24
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils.
Nat Commun, 15, 2024
7ZKY
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BU of 7zky by Molmil
Amyloid fibril from human systemic AA amyloidosis (vascular variant)
Descriptor: Amyloid protein A
Authors:Banerjee, S, Schmidt, M, Faendrich, M.
Deposit date:2022-04-13
Release date:2022-12-07
Method:ELECTRON MICROSCOPY (2.56 Å)
Cite:Amyloid fibril structure from the vascular variant of systemic AA amyloidosis.
Nat Commun, 13, 2022
6SDZ
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BU of 6sdz by Molmil
transthyritin derived amyloid fibril from patient with hereditary V30M ATTR amyloidosis
Descriptor: Transthyretin
Authors:Fritz, G, Agarwal, S, Faendrich, M.
Deposit date:2019-07-29
Release date:2019-11-13
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis.
Nat Commun, 10, 2019
7ZJ2
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BU of 7zj2 by Molmil
Amyloid fibril (in vitro) from full-length hnRNPA1 protein
Descriptor: Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1
Authors:Sharma, K, Banerjee, S, Schmidt, M, Faendrich, M.
Deposit date:2022-04-08
Release date:2023-08-02
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril.
J.Mol.Biol., 435, 2023
6IC3
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BU of 6ic3 by Molmil
AL amyloid fibril from a lambda 1 light chain
Descriptor: lambda 1 light chain fragment, residues 3-118
Authors:Fritz, G, Faendrich, M, Schmidt, M, Radamaker, L.
Deposit date:2018-12-02
Release date:2019-04-03
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis.
Nat Commun, 10, 2019
2OM3
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BU of 2om3 by Molmil
High-resolution cryo-EM structure of Tobacco Mosaic Virus
Descriptor: Coat protein, Tobacco Mosaic Virus RNA
Authors:Sachse, C.
Deposit date:2007-01-20
Release date:2007-10-16
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:High-resolution electron microscopy of helical specimens: a fresh look at tobacco mosaic virus.
J.Mol.Biol., 371, 2007
6ZCF
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BU of 6zcf by Molmil
Amyloid fibril morphology i (in vitro) from murine SAA1.1 protein
Descriptor: Serum amyloid A-2 protein
Authors:Bansal, A, Schmidt, M, Faendrich, M.
Deposit date:2020-06-11
Release date:2021-02-17
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils.
Nat Commun, 12, 2021
6ZCH
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BU of 6zch by Molmil
Amyloid fibril morphology II (ex vivo) from murine SAA1.1 protein.
Descriptor: Serum amyloid A-2 protein
Authors:Bansal, A, Schmidt, M, Faendrich, M.
Deposit date:2020-06-11
Release date:2021-02-17
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils.
Nat Commun, 12, 2021
8OQ4
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BU of 8oq4 by Molmil
AApoAII amyloid fibril Morphology II (ex vivo)
Descriptor: Apolipoprotein A-II
Authors:Andreotti, G, Schmidt, M, Faendrich, M.
Deposit date:2023-04-11
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils.
J.Mol.Biol., 436, 2024
8OQ5
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BU of 8oq5 by Molmil
AApoAII amyloid fibril Morphology I (ex vivo)
Descriptor: Apolipoprotein A-II
Authors:Andreotti, G, Schmidt, M, Faendrich, M.
Deposit date:2023-04-11
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils.
J.Mol.Biol., 436, 2024

 

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