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1IM9
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CRYSTAL STRUCTURE OF THE HUMAN NATURAL KILLER CELL INHIBITORY RECEPTOR KIR2DL1 BOUND TO ITS MHC LIGAND HLA-CW4
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, CW-4 CW*0401 ALPHA CHAIN, Beta-2 microglobulin, ...
Authors:Fan, Q.R., Long, E.O., Wiley, D.C.
Deposit date:2001-05-10
Release date:2001-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex.
Nat.Immunol., 2, 2001
1NKR
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INHIBITORY RECEPTOR (P58-CL42) FOR HUMAN NATURAL KILLER CELLS
Descriptor:P58-CL42 KIR
Authors:Fan, Q.R., Mosyak, L., Winter, C.C., Wagtmann, N., Long, E.O., Wiley, D.C.
Deposit date:1998-06-24
Release date:1998-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors.
Nature, 389, 1997
1QQD
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CRYSTAL STRUCTURE OF HLA-CW4, A LIGAND FOR THE KIR2D NATURAL KILLER CELL INHIBITORY RECEPTOR
Descriptor:HISTOCOMPATIBILITY LEUKOCYTE ANTIGEN (HLA)-CW4 (HEAVY CHAIN), BETA-2 MICROGLOBULIN, HLA-CW4 SPECIFIC PEPTIDE
Authors:Fan, Q.R., Wiley, D.C.
Deposit date:1999-06-03
Release date:1999-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of human histocompatibility leukocyte antigen (HLA)-Cw4, a ligand for the KIR2D natural killer cell inhibitory receptor
J.Exp.Med., 190, 1999
1XWD
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CRYSTAL STRUCTURE OF HUMAN FOLLICLE STIMULATING HORMONE COMPLEXED WITH ITS RECEPTOR
Descriptor:Glycoprotein hormones alpha chain, Follitropin beta chain, Follicle stimulating hormone receptor, ...
Authors:Fan, Q.R., Hendrickson, W.A.
Deposit date:2004-10-30
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structure of human follicle-stimulating hormone in complex with its receptor.
Nature, 433, 2005
1AO7
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COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201
Descriptor:HLA-A 0201, BETA-2 MICROGLOBULIN, TAX PEPTIDE, ...
Authors:Garboczi, D.N., Ghosh, P., Utz, U., Fan, Q.R., Biddison, W.E., Wiley, D.C.
Deposit date:1997-07-21
Release date:1997-09-17
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the complex between human T-cell receptor, viral peptide and HLA-A2.
Nature, 384, 1996
4F11
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR GBR2
Descriptor:Gamma-aminobutyric acid type B receptor subunit 2
Authors:Geng, Y., Xiong, D., Mosyak, L., Malito, D.L., Kniazeff, J., Chen, Y., Burmakina, S., Quick, M., Bush, M., Javitch, J.A., Pin, J.-P., Fan, Q.R.
Deposit date:2012-05-05
Release date:2012-06-06
Last modified:2012-08-15
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.
Nat.Neurosci., 15, 2012
4F12
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR GBR2
Descriptor:Gamma-aminobutyric acid type B receptor subunit 2, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE
Authors:Geng, Y., Xiong, D., Mosyak, L., Malito, D.L., Kniazeff, J., Chen, Y., Burmakina, S., Quick, M., Bush, M., Javitch, J.A., Pin, J.-P., Fan, Q.R.
Deposit date:2012-05-05
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.
Nat.Neurosci., 15, 2012
4MQE
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR IN THE APO FORM
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Geng, Y., Bush, M., Mosyak, L., Wang, F., Fan, Q.R.
Deposit date:2013-09-16
Release date:2013-12-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MQF
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR BOUND TO THE ANTAGONIST 2-HYDROXYSACLOFEN
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, 2-hydroxysaclofen, ...
Authors:Geng, Y., Bush, M., Mosyak, L., Wang, F., Fan, Q.R.
Deposit date:2013-09-16
Release date:2013-12-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR7
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR BOUND TO THE ANTAGONIST CGP54626
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, ...
Authors:Geng, Y., Bush, M., Mosyak, L., Wang, F., Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR8
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR BOUND TO THE ANTAGONIST CGP35348
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Geng, Y., Bush, M., Mosyak, L., Wang, F., Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MR9
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR BOUND TO THE ANTAGONIST SCH50911
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, [(2S)-5,5-dimethylmorpholin-2-yl]acetic acid, ...
Authors:Geng, Y., Bush, M., Mosyak, L., Wang, F., Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MRM
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR BOUND TO THE ANTAGONIST PHACLOFEN
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, phaclofen, ...
Authors:Geng, Y., Bush, M., Mosyak, L., Wang, F., Fan, Q.R.
Deposit date:2013-09-17
Release date:2013-12-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MS1
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR BOUND TO THE ANTAGONIST CGP46381
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, (S)-(3-aminopropyl)(cyclohexylmethyl)phosphinic acid, ...
Authors:Geng, Y., Bush, M., Mosyak, L., Wang, F., Fan, Q.R.
Deposit date:2013-09-18
Release date:2013-12-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MS3
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR BOUND TO THE ENDOGENOUS AGONIST GABA
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Geng, Y., Bush, M., Mosyak, L., Wang, F., Fan, Q.R.
Deposit date:2013-09-18
Release date:2013-12-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4MS4
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GABA(B) RECEPTOR BOUND TO THE AGONIST BACLOFEN
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, baclofen, ...
Authors:Geng, Y., Bush, M., Mosyak, L., Wang, F., Fan, Q.R.
Deposit date:2013-09-18
Release date:2013-12-11
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
4PAS
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HETERODIMERIC COILED-COIL STRUCTURE OF HUMAN GABA(B) RECEPTOR
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2
Authors:Burmakina, S., Geng, Y., Chen, Y., Fan, Q.R.
Deposit date:2014-04-10
Release date:2014-05-07
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Heterodimeric coiled-coil interactions of human GABAB receptor.
Proc.Natl.Acad.Sci.USA, 111, 2014
5K5S
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CRYSTAL STRUCTURE OF THE ACTIVE FORM OF HUMAN CALCIUM-SENSING RECEPTOR EXTRACELLULAR DOMAIN
Descriptor:Extracellular calcium-sensing receptor, TRYPTOPHAN, PHOSPHATE ION, ...
Authors:Geng, Y., Mosyak, L., Kurinov, I., Zuo, H., Sturchler, E., Cheng, T.C., Subramanyam, P., Brown, A.P., Brennan, S.C., Mun, H.-C., Bush, M., Chen, Y., Nguyen, T., Cao, B., Chang, D., Quick, M., Conigrave, A., Colecraft, H.M., McDonald, P., Fan, Q.R.
Deposit date:2016-05-23
Release date:2016-08-03
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural mechanism of ligand activation in human calcium-sensing receptor.
Elife, 5, 2016
5K5T
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CRYSTAL STRUCTURE OF THE INACTIVE FORM OF HUMAN CALCIUM-SENSING RECEPTOR EXTRACELLULAR DOMAIN
Descriptor:Extracellular calcium-sensing receptor, CALCIUM ION, SULFATE ION, ...
Authors:Geng, Y., Mosyak, L., Kurinov, I., Zuo, H., Sturchler, E., Cheng, T.C., Subramanyam, P., Brown, A.P., Brennan, S.C., Mun, H.-C., Bush, M., Chen, Y., Nguyen, T., Cao, B., Chang, D., Quick, M., Conigrave, A., Colecraft, H.M., McDonald, P., Fan, Q.R.
Deposit date:2016-05-23
Release date:2016-08-03
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural mechanism of ligand activation in human calcium-sensing receptor.
Elife, 5, 2016
1BD2
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COMPLEX BETWEEN HUMAN T-CELL RECEPTOR B7, VIRAL PEPTIDE (TAX) AND MHC CLASS I MOLECULE HLA-A 0201
Descriptor:HLA-A 0201, BETA-2 MICROGLOBULIN, TAX PEPTIDE, ...
Authors:Ding, Y.-H., Smith, K.J., Garboczi, D.N., Utz, U., Biddison, W.E., Wiley, D.C.
Deposit date:1998-05-12
Release date:1998-08-19
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.
Immunity, 8, 1998
1FO0
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MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX
Descriptor:PROTEIN (ALLOGENEIC H-2KB MHC CLASS I MOLECULE), PROTEIN (BETA-2 MICROGLOBULIN), NATURALLY PROCESSED OCTAPEPTIDE PBM1, ...
Authors:Reiser, J.B., Darnault, C., Guimezanes, A., Gregoire, C., Mosser, T., Schmitt-Verhulst, A.-M., Fontecilla-Camps, J.C., Malissen, B., Housset, D., Mazza, G.
Deposit date:2000-08-24
Release date:2000-10-02
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a T cell receptor bound to an allogeneic MHC molecule.
Nat.Immunol., 1, 2000
1KB5
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MURINE T-CELL RECEPTOR VARIABLE DOMAIN/FAB COMPLEX
Descriptor:KB5-C20 T-CELL ANTIGEN RECEPTOR, ANTIBODY DESIRE-1
Authors:Housset, D., Mazza, G., Gregoire, C., Piras, C., Malissen, B., Fontecilla-Camps, J.C.
Deposit date:1997-04-06
Release date:1998-04-08
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain.
EMBO J., 16, 1997
1NLR
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ENDO-1,4-BETA-GLUCANASE CELB2, CELLULASE, NATIVE STRUCTURE
Descriptor:ENDO-1,4-BETA-GLUCANASE
Authors:Sulzenbacher, G., Dupont, C., Davies, G.J.
Deposit date:1997-10-27
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Streptomyces lividans family 12 endoglucanase: construction of the catalytic cre, expression, and X-ray structure at 1.75 A resolution.
Biochemistry, 36, 1997
1QRN
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CRYSTAL STRUCTURE OF HUMAN A6 TCR COMPLEXED WITH HLA-A2 BOUND TO ALTERED HTLV-1 TAX PEPTIDE P6A
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
Authors:Ding, Y.H., Baker, B.M., Garboczi, D.N., Biddison, W.E., Wiley, D.C.
Deposit date:1999-06-14
Release date:1999-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999
1QSE
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STRUCTURE OF HUMAN A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE V7R
Descriptor:PROTEIN (MHC class I HLA-A), PROTEIN (beta-2 microglobulin), Tax Peptide V7R, ...
Authors:Ding, Y.H., Baker, B.M., Garboczi, D.N., Biddison, W.E., Wiley, D.C.
Deposit date:1999-06-21
Release date:1999-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999
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