Author results

1AOX
  • Download 1aox
  • View 1aox
Molmil generated image of 1aox
I DOMAIN FROM INTEGRIN ALPHA2-BETA1
Descriptor:INTEGRIN ALPHA 2 BETA, MAGNESIUM ION
Authors:Emsley, J., King, S.L., Bergelson, J.M., Liddington, R.C.
Deposit date:1997-07-13
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the I domain from integrin alpha2beta1.
J.Biol.Chem., 272, 1997
1AUQ
  • Download 1auq
  • View 1auq
Molmil generated image of 1auq
A1 DOMAIN OF VON WILLEBRAND FACTOR
Descriptor:A1 DOMAIN OF VON WILLEBRAND FACTOR, CADMIUM ION
Authors:Emsley, J., Cruz, M., Handin, R., Liddington, R.
Deposit date:1997-09-01
Release date:1998-10-14
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the von Willebrand Factor A1 domain and implications for the binding of platelet glycoprotein Ib.
J.Biol.Chem., 273, 1998
1DZI
  • Download 1dzi
  • View 1dzi
Molmil generated image of 1dzi
INTEGRIN ALPHA2 I DOMAIN / COLLAGEN COMPLEX
Descriptor:INTEGRIN, COLLAGEN, COBALT (II) ION
Authors:Emsley, j., Knight, G., Farndale, R., Barnes, M., Liddington, R.
Deposit date:2000-03-01
Release date:2001-03-01
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of Collagen Recognition by Integrin Alpha2Beta1
Cell(Cambridge,Mass.), 101, 2000
1Q7D
  • Download 1q7d
  • View 1q7d
Molmil generated image of 1q7d
STRUCTURE OF THE INTEGRIN ALPHA2BETA1 BINDING COLLAGEN PEPTIDE
Descriptor:collagen alfa 1(I) chain peptide GPOGPOGFOGERGPOGPOGPO
Authors:Emsley, J., Knight, C.G., Farndale, R.W., Barnes, M.J.
Deposit date:2003-08-18
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the Integrin alpha2beta1-binding Collagen Peptide.
J.Mol.Biol., 335, 2004
6EJX
  • Download 6ejx
  • View 6ejx
Molmil generated image of 6ejx
THE METAL ION-DEPENDENT ADHESION SITE (MIDAS) OF THE ALPHAMBETA2 INTEGRIN MAC-1 I-DOMAIN PROMISCUOUSLY AND COMPETITIVELY BINDS MULTIPLE LIGANDS IN THE REGULATION OF LEUKOCYTE FUNCTION
Descriptor:Platelet glycoprotein Ib alpha chain, IMIDAZOLE, DI(HYDROXYETHYL)ETHER, ...
Authors:Emsley, J., Saleem, M.
Deposit date:2017-09-24
Release date:2018-10-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The metal ion-dependent adhesion site (MIDAS) of the alphaMbeta2 integrin Mac-1 I-domain promiscuously and competitively binds multiple ligands in the regulation of Leukocyte function
To Be Published
1GWB
  • Download 1gwb
  • View 1gwb
Molmil generated image of 1gwb
STRUCTURE OF GLYCOPROTEIN 1B
Descriptor:PLATELET GLYCOPROTEIN IB ALPHA CHAIN, PLATINUM (II) ION, ACETIC ACID, ...
Authors:Emsley, J., Uff, S., Clemetson, K.J.M., Clemetson, J.M., Harrison, T.
Deposit date:2002-03-14
Release date:2003-02-06
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Platelet Glycoprotein Ib-Alpha N-Terminal Domain Reveals an Unmasking Mechanism of Receptor Activation
J.Biol.Chem., 277, 2002
1SAC
  • Download 1sac
  • View 1sac
Molmil generated image of 1sac
THE STRUCTURE OF PENTAMERIC HUMAN SERUM AMYLOID P COMPONENT
Descriptor:SERUM AMYLOID P COMPONENT, CALCIUM ION, ACETIC ACID
Authors:White, H.E., Emsley, J., O'Hara, B.P., Oliva, G., Srinivasan, N., Tickle, I.J., Blundell, T.L., Pepys, M.B., Wood, S.P.
Deposit date:1994-01-27
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of pentameric human serum amyloid P component.
Nature, 367, 1994
6I44
  • Download 6i44
  • View 6i44
Molmil generated image of 6i44
ALLOSTERIC ACTIVATION OF HUMAN PREKALLIKREIN BY APPLE DOMAIN DISC ROTATION
Descriptor:Plasma kallikrein, BENZAMIDINE, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Li, C., Pathak, M., MaCrae, K., Dreveny, I., Emsley, J.
Deposit date:2018-11-09
Release date:2019-03-06
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Plasma Kallikrein Structure Reveals Apple Domain Disc Rotated Conformation Compared to Factor XI.
J. Thromb. Haemost., 2019
6I58
  • Download 6i58
  • View 6i58
Molmil generated image of 6i58
ALLOSTERIC ACTIVATION OF HUMAN PREKALLIKREIN BY APPLE DOMAIN DISC ROTATION
Descriptor:Coagulation factor XI, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, C., Pathak, M., McCrae, K., Dreveny, I., Emsley, J.
Deposit date:2018-11-13
Release date:2019-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Plasma Kallikrein Structure Reveals Apple Domain Disc Rotated Conformation Compared to Factor XI.
J. Thromb. Haemost., 2019
1SJ7
  • Download 1sj7
  • View 1sj7
Molmil generated image of 1sj7
CRYSTAL STRUCTURE OF TALIN ROD 482-655
Descriptor:Talin 1, PLATINUM (II) ION
Authors:Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Critchley, D.R., Emsley, J.
Deposit date:2004-03-03
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
EMBO J., 23, 2004
1SJ8
  • Download 1sj8
  • View 1sj8
Molmil generated image of 1sj8
CRYSTAL STRUCTURE OF TALIN RESIDUES 482-789
Descriptor:Talin 1
Authors:Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Critchley, D.R., Emsley, J.
Deposit date:2004-03-03
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
EMBO J., 23, 2004
1T01
  • Download 1t01
  • View 1t01
Molmil generated image of 1t01
VINCULIN COMPLEXED WITH THE VBS1 HELIX FROM TALIN
Descriptor:unnamed protein product, Talin 1
Authors:Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Critchley, D.R., Emsley, J.
Deposit date:2004-04-07
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
2M32
  • Download 2m32
  • View 2m32
Molmil generated image of 2m32
ALPHA-1 INTEGRIN I-DOMAIN IN COMPLEX WITH GLOGEN TRIPLE HELICAL PEPTIDE
Descriptor:Integrin alpha-1, GLOGEN peptide, MAGNESIUM ION
Authors:Chin, Y., Headey, S., Mohanty, B., McEwan, P., Swarbrick, J., Mulhern, T., Emsley, J., Simpson, J., Scanlon, M.
Deposit date:2013-01-07
Release date:2013-11-06
Last modified:2014-02-12
Method:SOLUTION NMR
Cite:The Structure of Integrin alpha 1I Domain in Complex with a Collagen-mimetic Peptide.
J.Biol.Chem., 288, 2013
2OWL
  • Download 2owl
  • View 2owl
Molmil generated image of 2owl
CRYSTAL STRUCTURE OF E. COLI RDGC
Descriptor:Recombination-associated protein rdgC, CALCIUM ION
Authors:Briggs, G.S., McEwan, P.A., Yu, J., Moore, T., Emsley, J., Lloyd, R.G.
Deposit date:2007-02-16
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ring Structure of the Escherichia coli DNA-binding Protein RdgC Associated with Recombination and Replication Fork Repair.
J.Biol.Chem., 282, 2007
2QP2
  • Download 2qp2
  • View 2qp2
Molmil generated image of 2qp2
STRUCTURE OF A MACPF/PERFORIN-LIKE PROTEIN
Descriptor:Unknown protein, CALCIUM ION
Authors:Rosado, C.J., Buckle, A.M., Law, R.H.P., Butcher, R.E., Kan, W.T., Bird, C.H., Ung, K., Browne, K.A., Baran, K., Bashtannyk-Puhalovich, T.A., Faux, N.G., Wong, W., Porter, C.J., Pike, R.N., Ellisdon, A.M., Pearce, M.C., Bottomley, S.P., Emsley, J., Smith, A.I., Rossjohn, J., Hartland, E.L., Voskoboinik, I., Trapani, J.A., Bird, P.I., Dunstone, M.A., Whisstock, J.C.
Deposit date:2007-07-22
Release date:2007-09-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
4XDE
  • Download 4xde
  • View 4xde
Molmil generated image of 4xde
COAGULATION FACTOR XII PROTEASE DOMAIN CRYSTAL STRUCTURE
Descriptor:Coagulation factor XII, ISOPROPYL ALCOHOL, CITRATE ANION
Authors:Pathak, M., Wilmann, P., Awford, J., Li, C., Fisher, P.M., Dreveny, I., Dekker, L.V., Emsley, J.
Deposit date:2014-12-19
Release date:2015-02-04
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Coagulation factor XII protease domain crystal structure.
J.Thromb.Haemost., 13, 2015
4XE4
  • Download 4xe4
  • View 4xe4
Molmil generated image of 4xe4
COAGULATION FACTOR XII PROTEASE DOMAIN CRYSTAL STRUCTURE
Descriptor:Coagulation factor XII, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Pathak, M., Wilmann, P., Awford, J., Li, C., Fisher, P.M., Dreveny, I., Dekker, L.V., Emsley, J.
Deposit date:2014-12-22
Release date:2015-02-04
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Coagulation factor XII protease domain crystal structure.
J.Thromb.Haemost., 13, 2015
6GH9
  • Download 6gh9
  • View 6gh9
Molmil generated image of 6gh9
USP15 CATALYTIC DOMAIN IN COMPLEX WITH SMALL MOLECULE
Descriptor:Ubiquitin carboxyl-terminal hydrolase 15, ZINC ION, DIMETHYL SULFOXIDE, ...
Authors:Ward, S.J., Gratton, H.E., Caulton, S.G., Emsley, J., Dreveny, I.
Deposit date:2018-05-06
Release date:2018-09-26
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel.
J. Biol. Chem., 293, 2018
6GHA
  • Download 6gha
  • View 6gha
Molmil generated image of 6gha
USP15 CATALYTIC DOMAIN STRUCTURE
Descriptor:Ubiquitin carboxyl-terminal hydrolase 15,Ubiquitin carboxyl-terminal hydrolase 15, ZINC ION
Authors:Ward, S.J., Gratton, H.E., Caulton, S.G., Emsley, J., Dreveny, I.
Deposit date:2018-05-06
Release date:2018-09-26
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel.
J. Biol. Chem., 293, 2018
1U6H
  • Download 1u6h
  • View 1u6h
Molmil generated image of 1u6h
VINCULIN HEAD (0-258) IN COMPLEX WITH THE TALIN VINCULIN BINDING SITE 2 (849-879)
Descriptor:Vinculin, Talin
Authors:Fillingham, I., Gingras, A.R., Papagrigoriou, E., Patel, B., Emsley, J., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.
Deposit date:2004-07-30
Release date:2005-01-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Structure, 13, 2005
1U89
  • Download 1u89
  • View 1u89
Molmil generated image of 1u89
SOLUTION STRUCTURE OF VBS2 FRAGMENT OF TALIN
Descriptor:Talin 1
Authors:Fillingham, I., Gingras, A.R., Papagrigoriou, E., Patel, B., Emsley, J., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.
Deposit date:2004-08-05
Release date:2005-01-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Structure, 13, 2005
1XWJ
  • Download 1xwj
  • View 1xwj
Molmil generated image of 1xwj
VINCULIN HEAD (1-258) IN COMPLEX WITH THE TALIN VINCULIN BINDING SITE 3 (1945-1969)
Descriptor:Vinculin, Talin
Authors:Gingras, A.R., Papagrigoriou, E., Barsukov, I.L., Critchley, D.R., Emsley, J.
Deposit date:2004-11-01
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
1ZVZ
  • Download 1zvz
  • View 1zvz
Molmil generated image of 1zvz
VINCULIN HEAD (0-258) IN COMPLEX WITH THE TALIN ROD RESIDUE 820-844
Descriptor:Vinculin, Talin 1
Authors:Gingras, A.R., Ziegler, W.H., Barsukov, I.L., Roberts, G.C., Critchley, D.R., Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZW2
  • Download 1zw2
  • View 1zw2
Molmil generated image of 1zw2
VINCULIN HEAD (0-258) IN COMPLEX WITH THE TALIN ROD RESIDUES 2345-2369
Descriptor:Vinculin, talin
Authors:Gingras, A.R., Ziegler, W.H., Barsukov, I.L., Roberts, G.C., Critchley, D.R., Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZW3
  • Download 1zw3
  • View 1zw3
Molmil generated image of 1zw3
VINCULIN HEAD (0-258) IN COMPLEX WITH THE TALIN ROD RESIDUES 1630-1652
Descriptor:Vinculin, Talin 1
Authors:Gingras, A.R., Ziegler, W.H., Barsukov, I.L., Roberts, G.C., Critchley, D.R., Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
<123>