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6C3F
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AMYLOID FORMING PEPTIDE IYKVEI FROM TRANSTHYRETIN
Descriptor:ILE-TYR-LYS-VAL-GLU-ILE, trifluoroacetic acid
Authors:Saelices, L., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2018-01-09
Release date:2018-04-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C3G
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AMYLOID FORMING PEPTIDE KALGIS FROM TRANSTHYRETIN
Descriptor:LYS-ALA-LEU-GLY-ILE-SER, SULFATE ION, GLYCEROL
Authors:Saelices, L., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2018-01-09
Release date:2018-04-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C88
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE VAVHVF FROM TRANSTHYRETIN
Descriptor:VAL-ALA-VAL-HIS-VAL-PHE, GLYCEROL
Authors:Saelices, L., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2018-01-24
Release date:2018-04-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
3RUB
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CRYSTAL STRUCTURE OF THE UNACTIVATED FORM OF RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE FROM TOBACCO REFINED AT 2.0-ANGSTROMS RESOLUTION
Descriptor:RIBULOSE 1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE, FORM III, SULFATE ION, ...
Authors:Schreuder, H., Cascio, D., Curmi, P.M.G., Chapman, M.S., Suh, S.W., Eisenberg, D.S.
Deposit date:1990-05-25
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the unactivated form of ribulose-1,5-bisphosphate carboxylase/oxygenase from tobacco refined at 2.0-A resolution.
J.Biol.Chem., 267, 1992
1F0V
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CRYSTAL STRUCTURE OF AN RNASE A DIMER DISPLAYING A NEW TYPE OF 3D DOMAIN SWAPPING
Descriptor:5'-D(*CP*G)-3', RIBONUCLEASE A, PHOSPHATE ION, ...
Authors:Liu, Y.S., Gotte, G., Libonati, M., Eisenberg, D.S.
Deposit date:2000-05-17
Release date:2001-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A domain-swapped RNase A dimer with implications for amyloid formation
Nat.Struct.Biol., 8, 2001
4R0P
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IFQINS, AN AMYLOID FORMING SEGMENT FROM HUMAN LYSOZYME SPANNING RESIDUES 56-61
Descriptor:Lysozyme C
Authors:Sievers, S., Eisenberg, D.S., Sawaya, M.R.
Deposit date:2014-08-01
Release date:2014-12-17
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
4R0U
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TGVTAVA, AN AMYLOID FORMING SEGMENT FROM ALPHA SYNUCLEIN, RESIDUES 72-78
Descriptor:Alpha-synuclein
Authors:Ivanova, M.I., Eisenberg, D.S., Sawaya, M.R.
Deposit date:2014-08-01
Release date:2014-12-17
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
4R0W
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VVTGVTA, AN AMYLOID FORMING SEGMENT FROM ALPHA SYNUCLEIN, RESIDUES 70-76
Descriptor:Alpha-synuclein
Authors:Ivanova, M.I., Eisenberg, D.S., Sawaya, M.R.
Deposit date:2014-08-01
Release date:2014-12-17
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
4RIK
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AMYLOID FORMING SEGMENT, AVVTGVTAV, FROM THE NAC DOMAIN OF PARKINSON'S DISEASE PROTEIN ALPHA-SYNUCLEIN, RESIDUES 69-77
Descriptor:Alpha-synuclein
Authors:Guenther, E.L., Sawaya, M.R., Ivanova, M., Eisenberg, D.S.
Deposit date:2014-10-06
Release date:2015-08-26
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
4RIL
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STRUCTURE OF THE AMYLOID FORMING SEGMENT, GAVVTGVTAVA, FROM THE NAC DOMAIN OF PARKINSON'S DISEASE PROTEIN ALPHA-SYNUCLEIN, RESIDUES 68-78, DETERMINED BY ELECTRON DIFFRACTION
Descriptor:Alpha-synuclein
Authors:Rodriguez, J.A., Ivanova, M., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Johnson, L., Guenther, E., Sangwan, S., Hattne, J., Nannenga, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., Eisenberg, D.S.
Deposit date:2014-10-06
Release date:2015-08-26
Last modified:2018-04-25
Method:ELECTRON CRYSTALLOGRAPHY (1.43 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
4TKW
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN LEU55PRO MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-27
Release date:2015-10-21
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL4
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN VAL30MET MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL5
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN SER85PRO MUTANT
Descriptor:Transthyretin, SODIUM ION, CHLORIDE ION
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLK
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN SER85PRO/GLU92PRO MUTANT
Descriptor:Transthyretin, SODIUM ION, GLYCEROL, ...
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLS
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN GLU92PRO MUTANT
Descriptor:Transthyretin, PHOSPHATE ION, GLYCEROL, ...
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLT
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN
Descriptor:Transthyretin, MAGNESIUM ION
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLU
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN ALA108TRP MUTANT
Descriptor:Transthyretin, CHLORIDE ION
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-12-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of Human Transthyretin Ala108Trp Mutant
to be published
4TM9
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN THR119TRP MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-31
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TNE
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN THR119TYR MUTANT
Descriptor:Transthyretin, GLYCEROL
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-06-03
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TNF
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN LYS15TRP MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-06-03
Release date:2015-12-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of Human Transthyretin Lys15Trp Mutant
to be published
4TNG
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN THR119MET MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-06-04
Release date:2015-12-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of Human Transthyretin Thr119Met Mutant
to be published
4UNT
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INDUCED MONOMER OF THE MCG VARIABLE DOMAIN
Descriptor:IG LAMBDA CHAIN V-II REGION MGC, SULFATE ION
Authors:Brumshtein, B., Esswein, S.R., Landau, M., Ryan, C.M., Whitelegge, J.P., Phillips, M.L., Cascio, D., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2014-08-27
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
4UNU
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MCG - A DIMER OF LAMBDA VARIABLE DOMAINS
Descriptor:IG LAMBDA CHAIN V-II REGION MGC, POLYETHYLENE GLYCOL (N=34), SULFATE ION
Authors:Brumshtein, B., Esswein, S.R., Landau, M., Ryan, C., Whitelegge, J., Casio, D., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2014-08-27
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
4UNV
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COVALENT DIMER OF LAMBDA VARIABLE DOMAINS
Descriptor:IG LAMBDA CHAIN V-II REGION MGC, SULFATE ION
Authors:Brumshtein, B., Esswein, S., Landau, M., Ryan, C., Whitelegge, J., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2014-08-27
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
4XFN
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STRUCTURE OF AN AMYLOID FORMING PEPTIDE AEVVFT FROM HUMAN TRANSTHYRETIN
Descriptor:Amyloid forming peptide AEVVFT
Authors:Saelices, L., Sawaya, M., Cascio, D., Eisenberg, D.S.
Deposit date:2014-12-27
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015