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1D14
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STRUCTURE OF 11-DEOXYDAUNOMYCIN BOUND TO DNA CONTAINING A PHOSPHOROTHIOATE
Descriptor:DNA (5'-D(*CP*GP*TP*(AS)P*CP*G)-3'), 6-DEOXYDAUNOMYCIN
Authors:Williams, L.D., Egli, M., Ughetto, G., Van Der Marel, G.A., Van Boom, J.H., Quigley, G.J., Wang, A.H.-J., Rich, A., Frederick, C.A.
Deposit date:1989-10-20
Release date:1990-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate.
J.Mol.Biol., 215, 1990
1D17
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DNA-NOGALAMYCIN INTERACTIONS
Descriptor:DNA (5'-D(*(5CM)P*GP*TP*AP*(5CM)P*G)-3'), NOGALAMYCIN
Authors:Egli, M., Williams, L.D., Frederick, C.A., Rich, A.
Deposit date:1990-08-08
Release date:1991-07-15
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:DNA-nogalamycin interactions.
Biochemistry, 30, 1991
1D32
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DRUG-INDUCED DNA REPAIR: X-RAY STRUCTURE OF A DNA-DITERCALINIUM COMPLEX
Descriptor:DNA (5'-D(*CP*GP*CP*G)-3'), DITERCALINIUM
Authors:Gao, Q., Williams, L.D., Egli, M., Rabinovich, D., Chen, S.-L., Quigley, G.J., Rich, A.
Deposit date:1991-01-23
Release date:1992-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex.
Proc.Natl.Acad.Sci.USA, 88, 1991
1D48
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STRUCTURE OF THE PURE-SPERMINE FORM OF Z-DNA (MAGNESIUM FREE) AT 1 ANGSTROM RESOLUTION
Descriptor:DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE
Authors:Egli, M., Williams, L.D., Gao, Q., Rich, A.
Deposit date:1991-09-11
Release date:1992-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structure of the pure-spermine form of Z-DNA (magnesium free) at 1-A resolution.
Biochemistry, 30, 1991
1OFX
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CRYSTAL STRUCTURE OF AN OKAZAKI FRAGMENT AT 2 ANGSTROMS RESOLUTION
Descriptor:DNA (5'-D(*GP*GP*GP*TP*AP*TP*AP*CP*GP*C)-3'), DNA/RNA (5'-R(*GP*CP*GP*)-D(*TP*AP*TP*AP*CP*CP*C)-3'), SPERMINE
Authors:Egli, M., Usman, N., Zhang, S., Rich, A.
Deposit date:1991-10-17
Release date:1993-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of an Okazaki fragment at 2-A resolution.
Proc.Natl.Acad.Sci.USA, 89, 1992
1D87
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CONFORMATIONAL INFLUENCE OF THE RIBOSE 2'-HYDROXYL GROUP: CRYSTAL STRUCTURES OF DNA-RNA CHIMERIC DUPLEXES
Descriptor:DNA/RNA (5'-R(*GP*)-D(*CP*GP*TP*AP*TP*AP*CP*GP*C)-3')
Authors:Egli, M., Usman, N., Rich, A.
Deposit date:1992-08-28
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Conformational influence of the ribose 2'-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes.
Biochemistry, 32, 1993
1D88
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CONFORMATIONAL INFLUENCE OF THE RIBOSE 2'-HYDROXYL GROUP: CRYSTAL STRUCTURES OF DNA-RNA CHIMERIC DUPLEXES
Descriptor:DNA/RNA (5'-D(*GP*CP*GP*TP*)-R(*AP*)-D(*TP*AP*CP*GP*C)-3')
Authors:Egli, M., Usman, N., Rich, A.
Deposit date:1992-08-28
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational influence of the ribose 2'-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes.
Biochemistry, 32, 1993
2DES
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INTERACTIONS BETWEEN MORPHOLINYL ANTHRACYCLINES AND DNA: THE CRYSTAL STRUCTURE OF A MORPHOLINO DOXORUBICIN BOUND TO D(CGTACG)
Descriptor:DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), 3'-DESAMINO-3'-(2-METHOXY-4-MORPHOLINYL)-DOXORUBICIN, SODIUM ION, ...
Authors:Cirilli, M., Bachechi, F., Ughetto, G., Colonna, F.P., Capobianco, M.L.
Deposit date:1993-03-16
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Interactions between morpholinyl anthracyclines and DNA. The crystal structure of a morpholino doxorubicin bound to d(CGTACG).
J.Mol.Biol., 230, 1993
131D
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THE LOW-TEMPERATURE CRYSTAL STRUCTURE OF THE PURE-SPERMINE FORM OF Z-DNA REVEALS BINDING OF A SPERMINE MOLECULE IN THE MINOR GROOVE
Descriptor:DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE, SODIUM ION
Authors:Bancroft, D., Williams, L.D., Rich, A., Egli, M.
Deposit date:1993-06-18
Release date:1993-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove.
Biochemistry, 33, 1994
168D
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STABILIZING EFFECTS OF THE RNA 2'-SUBSTITUENT: CRYSTAL STRUCTURE OF AN OLIGODEOXYNUCLEOTIDE DUPLEX CONTAINING 2'-O-METHYLATED ADENOSINES
Descriptor:DNA/RNA (5'-D(*GP*CP*GP*TP*)-R(*(A2M)P*)-D(*TP*AP*CP*GP*C)-3')
Authors:Lubini, P., Zuercher, W., Egli, M.
Deposit date:1994-04-08
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Stabilizing effects of the RNA 2'-substituent: crystal structure of an oligodeoxynucleotide duplex containing 2'-O-methylated adenosines.
Chem.Biol., 1, 1994
1RXA
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CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES
Descriptor:RNA (5'-R(*CP*CP*CP*CP*GP*GP*GP*G)-3')
Authors:Portmann, S., Usman, N., Egli, M.
Deposit date:1995-05-05
Release date:1996-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of r(CCCCGGGG) in two distinct lattices.
Biochemistry, 34, 1995
1RXB
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CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES
Descriptor:RNA (5'-R(*CP*CP*CP*CP*GP*GP*GP*G)-3')
Authors:Portmann, S., Usman, N., Egli, M.
Deposit date:1995-05-05
Release date:1996-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of r(CCCCGGGG) in two distinct lattices.
Biochemistry, 34, 1995
247D
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CRYSTAL STRUCTURES OF AN A-FORM DUPLEX WITH SINGLE-ADENOSINE BULGES AND A CONFORMATIONAL BASIS FOR SITE SPECIFIC RNA SELF-CLEAVAGE
Descriptor:DNA/RNA (5'-R(*GP*CP*GP*)-D(*AP*TP*AP*TP*AP*)-R(*CP*GP*C)-3')
Authors:Portmann, S., Grimm, S., Workman, C., Usman, N., Egli, M.
Deposit date:1996-02-02
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of an A-form duplex with single-adenosine bulges and a conformational basis for site-specific RNA self-cleavage.
Chem.Biol., 3, 1996
248D
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CRYSTAL STRUCTURES OF AN A-FORM DUPLEX WITH SINGLE-ADENOSINE BULGES AND A CONFORMATIONAL BASIS FOR SITE SPECIFIC RNA SELF-CLEAVAGE
Descriptor:DNA/RNA (5'-R(*GP*CP*GP*)-D(*AP*TP*AP*TP*AP*)-R(*CP*GP*C)-3'), ORTHORHOMBIC, SPERMINE
Authors:Portmann, S., Grimm, S., Workman, C., Usman, N., Egli, M.
Deposit date:1996-02-02
Release date:1996-03-08
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structures of an A-form duplex with single-adenosine bulges and a conformational basis for site-specific RNA self-cleavage.
Chem.Biol., 3, 1996
259D
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RNA HYDRATION: A DETAILED LOOK
Descriptor:RNA (5'-R(*CP*CP*CP*CP*GP*GP*GP*G)-3')
Authors:Egli, M., Portmann, S., Usman, N.
Deposit date:1996-05-03
Release date:1996-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:RNA hydration: a detailed look.
Biochemistry, 35, 1996
290D
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CRYSTAL STRUCTURES OF OLIGODEOXYRIBONUCLEOTIDES CONTAINING 6'-ALPHA-METHYL AND 6'-ALPHA-HYDROXY CARBOCYCLIC THYMIDINES
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*(T32)P*(T32)P*CP*GP*CP*G)-3')
Authors:Portmann, S., Altmann, K.-H., Reynes, N., Egli, M.
Deposit date:1996-10-10
Release date:1996-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Oligodeoxyribonucleotides Containing 6'-alpha-Methyl and 6'-alpha-Hydroxy Carbocyclic Thymidines
J.Am.Chem.Soc., 119, 1997
291D
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CRYSTAL STRUCTURES OF OLIGODEOXYRIBONUCLEOTIDES CONTAINING 6'-ALPHA-METHYL AND 6'-ALPHA-HYDROXY CARBOCYCLIC THYMIDINES
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*(T48)P*(T48)P*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Portmann, S., Altmann, K.-H., Reynes, N., Egli, M.
Deposit date:1996-10-10
Release date:1996-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal Structures of Oligodeoxyribonucleotides Containing 6'-alpha-Methyl and 6'-alpha-Hydroxy Carbocyclic Thymidines
J.Am.Chem.Soc., 119, 1997
363D
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HIGH-RESOLUTION CRYSTAL STRUCTURE OF A FULLY MODIFIED N3'-> P5' PHOSPHORAMIDATE DNA DODECAMER DUPLEX
Descriptor:5'-D(*(C42)P*(G38)P*(C42)P*(G38)P*(A43)P*(A43)P*(NYM)P*(NYM)P*(C42)P*(G38)P*(C42)P*DG)-3', AMMONIUM ION, CHLORIDE ION
Authors:Tereshko, V., Gryaznov, S., Egli, M.
Deposit date:1997-11-26
Release date:1997-12-15
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Consequences of Replacing the DNA 3'-Oxygen by an Amino Group: High-Resolution Crystal Structure of a Fully Modified N3'--> P5' Phosphoramidate DNA Dodecamer Duplex
J.Am.Chem.Soc., 120, 1998
2DAU
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DICKERSON-DREW DNA DODECAMER, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Denisov, A., Bekiroglu, S., Maltseva, T., Sandstrom, A., Altmann, K.-H., Egli, M., Chattopadhyaya, J.
Deposit date:1998-01-20
Release date:1998-05-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution conformation of a carbocyclic analog of the Dickerson-Drew dodecamer: comparison with its own X-ray structure and that of the NMR structure of the native counterpart.
J.Biomol.Struct.Dyn., 16, 1998
1DAU
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ANALOG OF DICKERSON-DREW DNA DODECAMER WITH 6'-ALPHA-METHYL CARBOCYCLIC THYMIDINES, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*(T32)P*(T32)P*CP*GP*CP*G)-3')
Authors:Denisov, A., Bekiroglu, S., Maltseva, T., Sandstrom, A., Altmann, K.-H., Egli, M., Chattopadhyaya, J.
Deposit date:1998-01-21
Release date:1998-05-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution conformation of a carbocyclic analog of the Dickerson-Drew dodecamer: comparison with its own X-ray structure and that of the NMR structure of the native counterpart.
J.Biomol.Struct.Dyn., 16, 1998
388D
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CRYSTAL STRUCTURE OF B-DNA WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINES: IMPLICATIONS OF CONFORMATIONAL PREORGANIZATION FOR DUPLEX STABILITY
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*(TAF)P*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Berger, I., Tereshko, V., Ikeda, H., Marquez, V.E., Egli, M.
Deposit date:1998-04-20
Release date:1998-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability.
Nucleic Acids Res., 26, 1998
389D
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CRYSTAL STRUCTURE OF B-DNA WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINES: IMPLICATIONS OF CONFORMATIONAL PREORGANIZATION FOR DUPLEX STABILITY
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Berger, I., Tereshko, V., Ikeda, H., Marquez, V.E., Egli, M.
Deposit date:1998-04-20
Release date:1998-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability.
Nucleic Acids Res., 26, 1998
410D
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DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-ETHOXYMETHYLENE RIBONUCLEOSIDE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(T38)P*AP*CP*GP*C)-3'), SPERMINE
Authors:Tereshko, V., Portmann, S., Tay, E.C., Martin, P., Natt, F., Altmann, K.H., Egli, M.
Deposit date:1998-06-30
Release date:1998-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry, 37, 1998
411D
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DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-METHOXYETHYL RIBONUCLEOSIDE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(T39)P*AP*CP*GP*C)-3')
Authors:Tereshko, V., Portmann, S., Tay, E.C., Martin, P., Natt, F., Altmann, K.H., Egli, M.
Deposit date:1998-06-30
Release date:1998-07-17
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry, 37, 1998
412D
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DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-METHYL-[TRI(OXYETHYL)] RIBONUCLEOSIDE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(126)P*AP*CP*GP*C)-3'), MAGNESIUM ION
Authors:Tereshko, V., Portmann, S., Tay, E.C., Martin, P., Natt, F., Altmann, K.H., Egli, M.
Deposit date:1998-06-30
Release date:1998-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry, 37, 1998