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2RGU
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BU of 2rgu by Molmil
Crystal structure of complex of human DPP4 and inhibitor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-d ione, Dipeptidyl peptidase 4
Authors:Nar, H, Himmelsbach, F, Eckhardt, M.
Deposit date:2007-10-05
Release date:2007-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes.
J.Med.Chem., 50, 2007
7KDT
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BU of 7kdt by Molmil
Human Tom70 in complex with SARS CoV2 Orf9b
Descriptor: Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 370, 2020
7LMS
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BU of 7lms by Molmil
Structure of human SetD3 methyl-transferase in complex with 2A protease from Coxsackievirus B3
Descriptor: Actin-histidine N-methyltransferase, Protease 2A, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Verba, K.A, Schulze-Gahmen, U.
Deposit date:2021-02-05
Release date:2022-08-10
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3.
Nat Commun, 13, 2022

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