Author results

1LB2
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STRUCTURE OF THE E. COLI ALPHA C-TERMINAL DOMAIN OF RNA POLYMERASE IN COMPLEX WITH CAP AND DNA
Descriptor:5'-D(*CP*TP*TP*TP*TP*TP*TP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*AP*G)-3', CATABOLITE GENE ACTIVATOR PROTEIN, ...
Authors:Benoff, B., Yang, H., Lawson, C.L., Parkinson, G., Liu, J., Blatter, E., Ebright, Y.W., Berman, H.M., Ebright, R.H.
Deposit date:2002-04-01
Release date:2002-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of transcription activation: the CAP-alpha CTD-DNA complex.
Science, 297, 2002
4MEX
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH SALINAMIDE A
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Zhang, Y., Arnold, E., Ebright, R.H.
Deposit date:2013-08-27
Release date:2014-05-21
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3.902 Å)
Cite:Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
4MEY
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE HOLOENZYME
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Zhang, Y., Arnold, E., Ebright, R.H.
Deposit date:2013-08-27
Release date:2014-05-21
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3.948 Å)
Cite:Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
4MQ9
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH GE23077
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Ho, M.X., Arnold, E., Ebright, R.H., Zhang, Y., Tuske, S.
Deposit date:2013-09-16
Release date:2014-05-07
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
4OIN
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRANSCRIPTION INITIATION COMPLEX SOAKED WITH GE23077
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhang, Y., Ebright, R.H., Arnold, E.
Deposit date:2014-01-20
Release date:2014-05-07
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
4OIO
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS PRE-INSERTION SUBSTRATE COMPLEX FOR DE NOVO TRANSCRIPTION INITIATION
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhang, Y., Ebright, R.H., Arnold, E.
Deposit date:2014-01-20
Release date:2014-05-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
4OIP
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRANSCRIPTION INITIATION COMPLEX SOAKED WITH GE23077, ATP, AND CMPCPP
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhang, Y., Ebright, R.H., Arnold, E.
Deposit date:2014-01-20
Release date:2014-05-07
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
4OIQ
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRANSCRIPTION INITIATION COMPLEX SOAKED WITH GE23077 AND RIFAMPICIN
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhang, Y., Ebright, R.H., Arnold, E.
Deposit date:2014-01-20
Release date:2014-05-07
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (3.624 Å)
Cite:GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
4OIR
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX SOAKED WITH GE23077 AND RIFAMYCIN SV
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhang, Y., Ebright, R.H., Arnold, E.
Deposit date:2014-01-20
Release date:2014-05-07
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
6ASG
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS RNA POLYMERASE CORE ENZYME
Descriptor:DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, Y., Lin, W., Ying, R., Ebright, R.H.
Deposit date:2017-08-24
Release date:2018-04-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).
Mol. Cell, 70, 2018
1O3Q
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PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES
Descriptor:5'-D(*AP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*T)-3', CATABOLITE GENE ACTIVATOR PROTEIN, ...
Authors:Chen, S., Vojtechovsky, J., Parkinson, G.N., Ebright, R.H., Berman, H.M.
Deposit date:2003-03-18
Release date:2003-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
1O3R
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PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES
Descriptor:5'-D(*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*T)-3', CATABOLITE GENE ACTIVATOR PROTEIN, ...
Authors:Chen, S., Vojtechovsky, J., Parkinson, G.N., Ebright, R.H., Berman, H.M.
Deposit date:2003-03-18
Release date:2003-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
1O3S
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PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES
Descriptor:5'-D(*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*T)-3', CATABOLITE GENE ACTIVATOR PROTEIN, ...
Authors:Chen, S., Ebright, R.H., Berman, H.M.
Deposit date:2003-03-18
Release date:2003-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: Alteration of DNA Binding Specificity Through Alteration of DNA Kinking
J.Mol.Biol., 314, 2001
1O3T
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PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES
Descriptor:5'-D(*GP*CP*GP*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*TP*CP*G)-3', CATABOLITE GENE ACTIVATOR PROTEIN, ...
Authors:Chen, S., Vojtechovsky, J., Parkinson, G.N., Ebright, R.H., Berman, H.M.
Deposit date:2003-03-18
Release date:2003-04-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
4ZH2
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH CBR703
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Ebright, R.H.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (4.204 Å)
Cite:Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
4ZH3
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH CBRH16-BR
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Ebright, R.H.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (4.082 Å)
Cite:Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
4ZH4
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH CBRP18
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Ebright, R.H.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.993 Å)
Cite:Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
5UH5
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTION INITIATION COMPLEX CONTAINING 3 NT OF RNA
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W., Das, K., Feng, Y., Ebright, R.H.
Deposit date:2017-01-10
Release date:2017-04-12
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.746 Å)
Cite:Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
5UH6
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTION INITIATION COMPLEX CONTAINING 2NTRNA IN COMPLEX WITH RIFAMPIN
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W., Das, K., Feng, Y., Ebright, R.H.
Deposit date:2017-01-11
Release date:2017-04-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.837 Å)
Cite:Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
5UH7
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CRYSTAL STRUCTURE OF BETA'MTBSI OF MYCOBACTERIUM TUBERCULOSIS RNA POLYMERASE
Descriptor:DNA-directed RNA polymerase subunit beta'
Authors:Lin, W., Das, K., Feng, Y., Ebright, R.H.
Deposit date:2017-01-11
Release date:2017-04-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
5UH8
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTION INITIATION COMPLEX CONTAINING 4NT RNA
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W., Das, K., Feng, Y., Ebright, R.H.
Deposit date:2017-01-11
Release date:2017-04-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.176 Å)
Cite:Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
5UH9
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTION INITIATION COMPLEX CONTAINING 2NT RNA
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W., Das, K., Feng, Y., Ebright, R.H.
Deposit date:2017-01-11
Release date:2017-04-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.402 Å)
Cite:Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
5UHA
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTION INITIATION COMPLEX
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W., Das, K., Feng, Y., Ebright, R.H.
Deposit date:2017-01-11
Release date:2017-04-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.906 Å)
Cite:Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
5UHB
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTION INITIATION COMPLEX IN COMPLEX WITH RIFAMPIN
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W., Das, K., Feng, Y., Ebright, R.H.
Deposit date:2017-01-11
Release date:2017-04-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.29 Å)
Cite:Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
5UHC
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTION INITIATION COMPLEX CONTAINING 3NT RNA IN COMPLEX WITH RIFAMPIN
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W., Das, K., Feng, Y., Ebright, R.H.
Deposit date:2017-01-11
Release date:2017-04-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.796 Å)
Cite:Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
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