Author results

2I5E
  • Download 2i5e
  • View 2i5e
Molmil generated image of 2i5e
CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION MM2497 FROM METHANOSARCINA MAZEI GO1, PROBABLE NUCLEOTIDYLTRANSFERASE
分子名称:Hypothetical protein MM_2497, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER
著者Tan, K., Du, J., Clancy, S., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2006-08-24
公開日2006-09-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of a hypothetical protein MM_2497 from Methanosarcina mazei Go1
To be Published
2F5J
  • Download 2f5j
  • View 2f5j
Molmil generated image of 2f5j
CRYSTAL STRUCTURE OF MRG DOMAIN FROM HUMAN MRG15
分子名称:Mortality factor 4-like protein 1
著者Zhang, P., Du, J., Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14
Protein Sci., 15, 2006
2F5K
  • Download 2f5k
  • View 2f5k
Molmil generated image of 2f5k
CRYSTAL STRUCTURE OF THE CHROMO DOMAIN OF HUMAN MRG15
分子名称:Mortality factor 4-like protein 1
著者Zhang, P., Du, J., Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.
Nucleic Acids Res., 34, 2006
2OSL
  • Download 2osl
  • View 2osl
Molmil generated image of 2osl
CRYSTAL STRUCTURE OF RITUXIMAB FAB IN COMPLEX WITH AN EPITOPE PEPTIDE
分子名称:light chain of the Rituximab Fab fragment, heavy chain of the Rituximab Fab fragment, B-lymphocyte antigen CD20
著者Du, J., Zhong, C., Ding, J.
登録日2007-02-06
公開日2007-04-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for recognition of CD20 by therapeutic antibody Rituximab
J.Biol.Chem., 282, 2007
2UZR
  • Download 2uzr
  • View 2uzr
Molmil generated image of 2uzr
A TRANSFORMING MUTATION IN THE PLECKSTRIN HOMOLOGY DOMAIN OF AKT1 IN CANCER (AKT1-PH_E17K)
分子名称:RAC-alpha serine/threonine-protein kinase
著者Carpten, J.D., Faber, A.L., Horn, C., Donoho, G.P., Briggs, S.L., Robbins, C.M., Hostetter, G., Boguslawski, S., Moses, T.Y., Savage, S., Uhlik, M., Lin, A., Du, J., Qian, Y.W., Zeckner, D.J., Tucker-Kellogg, G., Touchman, J., Patel, K., Mousses, S., Bittner, M., Schevitz, R., Lai, M.H., Blanchard, K.L., Thomas, J.E.
登録日2007-05-01
公開日2007-07-17
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
2UZS
  • Download 2uzs
  • View 2uzs
Molmil generated image of 2uzs
A TRANSFORMING MUTATION IN THE PLECKSTRIN HOMOLOGY DOMAIN OF AKT1 IN CANCER (AKT1-PH_E17K)
分子名称:RAC-alpha serine/threonine-protein kinase, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE
著者Carpten, J.D., Faber, A.L., Horn, C., Donoho, G.P., Briggs, S.L., Robbins, C.M., Hostetter, G., Boguslawski, S., Moses, T.Y., Savage, S., Uhlik, M., Lin, A., Du, J., Qian, Y.W., Zeckner, D.J., Tucker-Kellogg, G., Touchman, J., Patel, K., Mousses, S., Bittner, M., Schevitz, R., Lai, M.H., Blanchard, K.L., Thomas, J.E.
登録日2007-05-01
公開日2007-07-17
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
2PVP
  • Download 2pvp
  • View 2pvp
Molmil generated image of 2pvp
CRYSTAL STRUCTURE OF D-ALANINE-D-ALANINE LIGASE FROM HELICOBACTER PYLORI
分子名称:D-alanine-D-alanine ligase
著者Wu, D., Zhang, L., Jiang, H., Shen, X.
登録日2007-05-10
公開日2008-04-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori.
Proteins, 72, 2008
3BKY
  • Download 3bky
  • View 3bky
Molmil generated image of 3bky
CRYSTAL STRUCTURE OF CHIMERIC ANTIBODY C2H7 FAB IN COMPLEX WITH A CD20 PEPTIDE
分子名称:the Fab fragment of chimeric 2H7, heavy chain, light chain, ...
著者Du, J., Zhong, C., Ding, J.
登録日2007-12-07
公開日2008-04-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal structure of chimeric antibody C2H7 Fab in complex with a CD20 peptide
Mol.Immunol., 45, 2008
2RJG
  • Download 2rjg
  • View 2rjg
Molmil generated image of 2rjg
CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE FROM ESCHERICHIA COLI
分子名称:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
著者Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
登録日2007-10-15
公開日2008-07-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
2RJH
  • Download 2rjh
  • View 2rjh
Molmil generated image of 2rjh
CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE IN D-CYCLOSERINE-BOUND FORM FROM ESCHERICHIA COLI
分子名称:Alanine racemase, SULFATE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE
著者Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
登録日2007-10-15
公開日2008-07-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8T
  • Download 3b8t
  • View 3b8t
Molmil generated image of 3b8t
CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT P219A
分子名称:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
著者Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
登録日2007-11-02
公開日2008-07-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8U
  • Download 3b8u
  • View 3b8u
Molmil generated image of 3b8u
CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221A
分子名称:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
著者Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
登録日2007-11-02
公開日2008-07-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8V
  • Download 3b8v
  • View 3b8v
Molmil generated image of 3b8v
CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221K
分子名称:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
著者Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
登録日2007-11-02
公開日2008-07-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8W
  • Download 3b8w
  • View 3b8w
Molmil generated image of 3b8w
CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221P
分子名称:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
著者Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
登録日2007-11-02
公開日2008-07-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3DEH
  • Download 3deh
  • View 3deh
Molmil generated image of 3deh
CRYSTAL STRUCTURES OF CASPASE-3 WITH BOUND ISOQUINOLINE-1,3,4-TRIONE DERIVATIVE INHIBITORS
分子名称:Caspase-3, isoquinoline-1,3,4(2H)-trione
著者Wu, J., Du, J., Li, J., Ding, J.
登録日2008-06-10
公開日2008-09-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species
J.Biol.Chem., 283, 2008
3DEI
  • Download 3dei
  • View 3dei
Molmil generated image of 3dei
CRYSTAL STRUCTURES OF CASPASE-3 WITH BOUND ISOQUINOLINE-1,3,4-TRIONE DERIVATIVE INHIBITORS
分子名称:Caspase-3, (1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate
著者Wu, J., Du, J., Li, J., Ding, J.
登録日2008-06-10
公開日2008-09-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species
J.Biol.Chem., 283, 2008
3DEJ
  • Download 3dej
  • View 3dej
Molmil generated image of 3dej
CRYSTAL STRUCTURES OF CASPASE-3 WITH BOUND ISOQUINOLINE-1,3,4-TRIONE DERIVATIVE INHIBITORS
分子名称:Caspase-3, (1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate
著者Wu, J., Du, J., Li, J., Ding, J.
登録日2008-06-10
公開日2008-09-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species
J.Biol.Chem., 283, 2008
3DEK
  • Download 3dek
  • View 3dek
Molmil generated image of 3dek
CRYSTAL STRUCTURES OF CASPASE-3 WITH BOUND ISOQUINOLINE-1,3,4-TRIONE DERIVATIVE INHIBITORS
分子名称:Caspase-3, N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide
著者Wu, J., Du, J., Li, J., Ding, J.
登録日2008-06-10
公開日2008-09-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species
J.Biol.Chem., 283, 2008
3CXD
  • Download 3cxd
  • View 3cxd
Molmil generated image of 3cxd
CRYSTAL STRUCTURE OF ANTI-OSTEOPONTIN ANTIBODY 23C3 IN COMPLEX WITH ITS EPITOPE PEPTIDE
分子名称:Fab fragment of anti-osteopontin antibody 23C3, Light chain, Heavy chain, ...
著者Du, J., Yang, H., Zhong, C., Ding, J.
登録日2008-04-24
公開日2008-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
3DSF
  • Download 3dsf
  • View 3dsf
Molmil generated image of 3dsf
CRYSTAL STRUCTURE OF ANTI-OSTEOPONTIN ANTIBODY 23C3 IN COMPLEX WITH W43A MUTATED EPITOPE PEPTIDE
分子名称:Fab fragment of anti-osteopontin antibody 23C3, Light chain, Heavy chain, ...
著者Du, J., Zhong, C., Yang, H., Ding, J.
登録日2008-07-12
公開日2008-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
3FGG
  • Download 3fgg
  • View 3fgg
Molmil generated image of 3fgg
CRYSTAL STRUCTURE OF PUTATIVE ECF-TYPE SIGMA FACTOR NEGATIVE EFFECTOR FROM BACILLUS CEREUS
分子名称:uncharacterized protein BCE2196, ZINC ION, GLYCEROL
著者Kim, Y., Nocek, B., Maltseva, N., Joachimiak, G., Du, J., Jedrzejczak, R., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2008-12-05
公開日2009-01-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Putative ECF-type Sigma Factor Negative Effector from Bacillus cereus
To be Published
3FH3
  • Download 3fh3
  • View 3fh3
Molmil generated image of 3fh3
CRYSTAL STRUCTURE OF A PUTATIVE ECF-TYPE SIGMA FACTOR NEGATIVE EFFECTOR FROM BACILLUS ANTHRACIS STR. STERNE
分子名称:putative ECF-type sigma factor negative effector, NICKEL (II) ION
著者Nocek, B., Kim, Y., Joachimiak, G., Du, J., Gornicki, P., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2008-12-08
公開日2009-01-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Crystal structure of a putative ECF-type sigma factor negative effector from Bacillus anthracis str. Sterne
To be Published
3GIZ
  • Download 3giz
  • View 3giz
Molmil generated image of 3giz
CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF ANTI-CD20 ANTIBODY OFATUMUMAB
分子名称:Fab fragment of anti-CD20 antibody Ofatumumab, light chain, heavy chain, ...
著者Du, J., Yang, H., Ding, J.
登録日2009-03-07
公開日2009-05-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20
Mol.Immunol., 46, 2009
3ED0
  • Download 3ed0
  • View 3ed0
Molmil generated image of 3ed0
CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABZ) FROM HELICOBACTER PYLORI IN COMPLEX WITH EMODIN
分子名称:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ...
著者Zhang, L., Zhang, H., Liu, W., Guo, Y., Shen, X., Jiang, H.
登録日2008-09-02
公開日2009-07-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization
BMC MICROBIOL., 9, 2009
2RQK
  • Download 2rqk
  • View 2rqk
Molmil generated image of 2rqk
NMR SOLUTION STRUCTURE OF MESODERM DEVELOPMENT (MESD) - CLOSED CONFORMATION
分子名称:Mesoderm development candidate 2
著者Koehler, C., Lighthouse, J.K., Werther, T., Andersen, O.M., Diehl, A., Schmieder, P., Holdener, B.C., Oschkinat, H.
登録日2009-08-06
公開日2009-08-25
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The Structure of MESD45-184 Brings Light into the Mechanism of LDLR Family Folding
Structure, 19, 2011