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5VYB
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BU of 5vyb by Molmil
Structure of the carbohydrate recognition domain of Dectin-2 complexed with a mammalian-type high mannose Man9GlcNAc2 oligosaccharide
Descriptor: C-type lectin domain family 6 member A, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Feinberg, H, Jegouzo, S.A.F, Rex, M.J, Drickamer, K, Taylor, M.E, Weis, W.I.
Deposit date:2017-05-24
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanism of pathogen recognition by human dectin-2.
J. Biol. Chem., 292, 2017
2MSB
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BU of 2msb by Molmil
STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN COMPLEXED WITH AN OLIGOSACCHARIDE
Descriptor: CALCIUM ION, MANNOSE-BINDING PROTEIN-A, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Weis, W.I, Drickamer, K, Hendrickson, W.A.
Deposit date:1992-07-28
Release date:1993-10-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of a C-type mannose-binding protein complexed with an oligosaccharide.
Nature, 360, 1992
1XAR
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BU of 1xar by Molmil
Crystal Structure of a fragment of DC-SIGNR (containing the carbohydrate recognition domain and two repeats of the neck).
Descriptor: CD209 antigen-like protein 1, SODIUM ION
Authors:Feinberg, H, Guo, Y, Mitchell, D.A, Drickamer, K, Weis, W.I.
Deposit date:2004-08-26
Release date:2004-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Extended Neck Regions Stabilize Tetramers of the Receptors DC-SIGN and DC-SIGNR
J.Biol.Chem., 280, 2005
5KTH
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BU of 5kth by Molmil
Structure of cow mincle complexed with brartemicin
Descriptor: 2,4-dihydroxy-6-methyl Benzoic acid, CALCIUM ION, TRIETHYLENE GLYCOL, ...
Authors:Feinberg, H, Rambaruth, N.D.S, Jegouzo, S.A.F, Jacobsen, K.M, Djurhuus, R, Poulsen, T.B, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2016-07-11
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
5KTI
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BU of 5kti by Molmil
Structure of cow mincle complexed with KMJ1
Descriptor: 2,3-dimethoxybenzoic acid, CALCIUM ION, TRIETHYLENE GLYCOL, ...
Authors:Feinberg, H, Rambaruth, N.D.S, Jegouzo, S.A.F, Jacobsen, K.M, Djurhuus, R, Poulsen, T.B, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2016-07-11
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
3JQH
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BU of 3jqh by Molmil
Structure of the neck region of the glycan-binding receptor DC-SIGNR
Descriptor: C-type lectin domain family 4 member M
Authors:Feinberg, H, Tso, C.K.W, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2009-09-06
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Segmented helical structure of the neck region of the glycan-binding receptor DC-SIGNR.
J.Mol.Biol., 394, 2009
1RDN
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BU of 1rdn by Molmil
MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT COMPLEX WITH ALPHA-METHYL-D-N-ACETYLGLUCOSAMINIDE
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Ng, K.K.-S, Drickamer, K, Weis, W.I.
Deposit date:1995-09-05
Release date:1996-03-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
J.Biol.Chem., 271, 1996
1RDJ
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BU of 1rdj by Molmil
MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT COMPLEX WITH BETA-METHYL-L-FUCOPYRANOSIDE
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-C, ...
Authors:Ng, K.K.-S, Drickamer, K, Weis, W.I.
Deposit date:1995-09-05
Release date:1996-03-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
J.Biol.Chem., 271, 1996
1RDK
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BU of 1rdk by Molmil
MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT COMPLEX WITH D-GALACTOSE
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-C, ...
Authors:Ng, K.K.-S, Drickamer, K, Weis, W.I.
Deposit date:1995-09-05
Release date:1996-03-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
J.Biol.Chem., 271, 1996
1RDL
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BU of 1rdl by Molmil
MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT COMPLEX WITH ALPHA-METHYL-D-MANNOPYRANOSIDE (0.2 M)
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-C, ...
Authors:Ng, K.K.-S, Drickamer, K, Weis, W.I.
Deposit date:1995-09-05
Release date:1996-03-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
J.Biol.Chem., 271, 1996
1RDM
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BU of 1rdm by Molmil
MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT COMPLEX WITH ALPHA-METHYL-D-MANNOPYRANOSIDE (1.3 M)
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-C, ...
Authors:Ng, K.K.-S, Drickamer, K, Weis, W.I.
Deposit date:1995-09-05
Release date:1996-03-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
J.Biol.Chem., 271, 1996
1RDI
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BU of 1rdi by Molmil
MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT COMPLEX WITH ALPHA-METHYL-L-FUCOPYRANOSIDE
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-C, ...
Authors:Ng, K.K.-S, Drickamer, K, Weis, W.I.
Deposit date:1995-09-05
Release date:1996-03-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
J.Biol.Chem., 271, 1996
1RDO
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BU of 1rdo by Molmil
MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-C
Authors:Ng, K.K.-S, Drickamer, K, Weis, W.I.
Deposit date:1995-09-05
Release date:1996-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
J.Biol.Chem., 271, 1996
1RTM
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BU of 1rtm by Molmil
TRIMERIC STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Weis, W.I, Drickamer, K.
Deposit date:1994-11-21
Release date:1995-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Trimeric structure of a C-type mannose-binding protein.
Structure, 2, 1994
1FIH
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BU of 1fih by Molmil
N-ACETYLGALACTOSAMINE BINDING MUTANT OF MANNOSE-BINDING PROTEIN A (QPDWG-HDRPY), COMPLEX WITH N-ACETYLGALACTOSAMINE
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Feinberg, H, Torgerson, D, Drickamer, K, Weis, W.I.
Deposit date:2000-08-03
Release date:2000-08-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanism of pH-dependent N-acetylgalactosamine binding by a functional mimic of the hepatocyte asialoglycoprotein receptor.
J.Biol.Chem., 275, 2000
1FIF
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BU of 1fif by Molmil
N-ACETYLGALACTOSAMINE-SELECTIVE MUTANT OF MANNOSE-BINDING PROTEIN-A (QPDWG-HDRPY)
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-A
Authors:Feinberg, H, Torgersen, D, Drickamer, K, Weis, W.I.
Deposit date:2000-08-03
Release date:2000-08-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanism of pH-dependent N-acetylgalactosamine binding by a functional mimic of the hepatocyte asialoglycoprotein receptor.
J.Biol.Chem., 275, 2000
4ZET
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BU of 4zet by Molmil
Blood dendritic cell antigen 2 (BDCA-2) complexed with GalGlcNAcMan
Descriptor: C-type lectin domain family 4 member C, CALCIUM ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose
Authors:Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2015-04-20
Release date:2015-05-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2.
J.Biol.Chem., 290, 2015
4ZES
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BU of 4zes by Molmil
Blood dendritic cell antigen 2 (BDCA-2) complexed with methyl-mannoside
Descriptor: C-type lectin domain family 4 member C, CALCIUM ION, MAGNESIUM ION, ...
Authors:Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2015-04-20
Release date:2015-05-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2.
J.Biol.Chem., 290, 2015
4ZRW
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BU of 4zrw by Molmil
Structure of cow mincle complexed with trehalose
Descriptor: CALCIUM ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, mincle protein
Authors:Feinberg, H, Rambaruth, N.D.S, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2015-05-12
Release date:2016-05-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
4ZRV
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BU of 4zrv by Molmil
Structure of cow mincle CRD complexed with trehalose mono butyrate
Descriptor: 6-O-butanoyl-alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
Authors:Feinberg, H, Rambaruth, N.D.S, Taylor, M.E, Drickamer, K, Weis, W.I.
Deposit date:2015-05-12
Release date:2016-05-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.095 Å)
Cite:Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
2IT6
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BU of 2it6 by Molmil
Crystal Structure of DCSIGN-CRD with man2
Descriptor: CALCIUM ION, CD209 antigen, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
Authors:Weis, W.I, Feinberg, H, Castelli, R, Drickamer, K, Seeberger, P.H.
Deposit date:2006-10-19
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins.
J.Biol.Chem., 282, 2007
2IT5
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BU of 2it5 by Molmil
Crystal Structure of DCSIGN-CRD with man6
Descriptor: CALCIUM ION, CD209 antigen, DCSIGN-CRD, ...
Authors:Weis, W.I, Feinberg, H, Castelli, R, Drickamer, K, Seeberger, P.H.
Deposit date:2006-10-19
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins.
J.Biol.Chem., 282, 2007
3P5F
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BU of 3p5f by Molmil
Structure of the carbohydrate-recognition domain of human Langerin with man2 (Man alpha1-2 Man)
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, alpha-D-mannopyranose, ...
Authors:Feinberg, H, Taylor, M.E, Razi, N, McBride, R, Knirel, Y.A, Graham, S.A, Drickamer, K, Weis, W.I.
Deposit date:2010-10-08
Release date:2010-12-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.7501 Å)
Cite:Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site.
J.Mol.Biol., 405, 2011
3P5H
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BU of 3p5h by Molmil
Structure of the carbohydrate-recognition domain of human Langerin with Laminaritriose
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, beta-D-glucopyranose, ...
Authors:Feinberg, H, Taylor, M.E, Razi, N, McBride, R, Knirel, Y.A, Graham, S.A, Drickamer, K, Weis, W.I.
Deposit date:2010-10-08
Release date:2010-12-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6051 Å)
Cite:Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site.
J.Mol.Biol., 405, 2011
3P5E
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BU of 3p5e by Molmil
Structure of the carbohydrate-recognition domain of human Langerin with man4 (Man alpha1-3(Man alpha1-6)Man alpha1-6Man)
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, alpha-D-mannopyranose
Authors:Feinberg, H, Taylor, M.E, Razi, N, McBride, R, Knirel, Y.A, Graham, S.A, Drickamer, K, Weis, W.I.
Deposit date:2010-10-08
Release date:2010-12-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.7012 Å)
Cite:Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site.
J.Mol.Biol., 405, 2011

 

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