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2W1B
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BU of 2w1b by Molmil
The structure of the efflux pump AcrB in complex with bile acid
Descriptor: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACRIFLAVIN RESISTANCE PROTEIN B
Authors:Drew, D, Klepsch, M.M, Newstead, S, Flaig, R, De Gier, J.W, Iwata, S, Beis, K.
Deposit date:2008-10-17
Release date:2008-12-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:The Structure of the Efflux Pump Acrb in Complex with Bile Acid.
Mol.Membr.Biol., 25, 2008
7S24
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BU of 7s24 by Molmil
Crystal structure of the Na+/H+ antiporter NhaA at pH 6.5
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Na(+)/H(+) antiporter NhaA, PENTAETHYLENE GLYCOL
Authors:Drew, D, Brock, J, Uzdavinys, P, Matsuoka, R.
Deposit date:2021-09-03
Release date:2022-08-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Na + /H + antiporter NhaA at active pH reveals the mechanistic basis for pH sensing.
Nat Commun, 13, 2022
4ATV
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BU of 4atv by Molmil
STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
Descriptor: DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION
Authors:Drew, D, Lee, C, Iwata, S, Cameron, A.D.
Deposit date:2012-05-10
Release date:2013-07-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
4AU5
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BU of 4au5 by Molmil
Structure of the NhaA dimer, crystallised at low pH
Descriptor: DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION
Authors:Drew, D, Lee, C, Iwata, S, Cameron, A.D.
Deposit date:2012-05-14
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.696 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
6Z3Z
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BU of 6z3z by Molmil
CryoEM structure of horse sodium/proton exchanger NHE9 without C-terminal regulatory domain in an inward-facing conformation
Descriptor: Sodium/hydrogen exchanger
Authors:Winkelmann, I, Matsuoka, R, Meier, P, Drew, D.
Deposit date:2020-05-22
Release date:2020-11-04
Last modified:2021-03-17
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9.
Embo J., 39, 2020
8OTW
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BU of 8otw by Molmil
Cryo-EM structure of Strongylocentrotus purpuratus SLC9C1 in presence of cAMP
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Sperm-specific sodium proton exchanger
Authors:Yeo, H, Mehta, V, Gulati, A, Drew, D.
Deposit date:2023-04-21
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Structure and electromechanical coupling of a voltage-gated Na + /H + exchanger.
Nature, 623, 2023
8BY2
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BU of 8by2 by Molmil
Structure of the K+/H+ exchanger KefC with GSH.
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE MONOPHOSPHATE, GLUTATHIONE, ...
Authors:Gulati, A, Drew, D.
Deposit date:2022-12-11
Release date:2023-12-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structure and mechanism of the K+/H+ exchanger KefC
To be published
8BXG
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BU of 8bxg by Molmil
Structure of the K/H exchanger KefC.
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE MONOPHOSPHATE, Glutathione-regulated potassium-efflux system protein KefC, ...
Authors:Gulati, A, Drew, D.
Deposit date:2022-12-08
Release date:2023-12-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structure and mechanism of the K+/H+ exchanger KefC
To be published
8OTX
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BU of 8otx by Molmil
Cryo-EM structure of Strongylocentrotus purpuratus sperm-specific Na+/H+ exchanger SLC9C1 in nanodisc
Descriptor: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Sperm-specific sodium proton exchanger
Authors:Yeo, H, Mehta, V, Gulati, A, Drew, D.
Deposit date:2023-04-21
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structure and electromechanical coupling of a voltage-gated Na + /H + exchanger.
Nature, 623, 2023
8OTQ
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BU of 8otq by Molmil
Cryo-EM structure of Strongylocentrotus purpuratus sperm-specific Na+/H+ exchanger SLC9C1 in GDN
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, PALMITIC ACID, Sperm-specific sodium proton exchanger
Authors:Yeo, H, Mehta, V, Gulati, A, Drew, D.
Deposit date:2023-04-21
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structure and electromechanical coupling of a voltage-gated Na + /H + exchanger.
Nature, 623, 2023
8PS0
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BU of 8ps0 by Molmil
Cryo-EM structure of Sodium proton exchanger NhaA with bound cardiolipin
Descriptor: CARDIOLIPIN, Na(+)/H(+) antiporter NhaA
Authors:Gulati, A, Meier, P, Kokane, S, Drew, D.
Deposit date:2023-07-13
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Cryo-EM structure of Sodium proton exchanger NhaA with bound cardiolipin
To Be Published
6I1R
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BU of 6i1r by Molmil
Crystal structure of CMP bound CST in an outward facing conformation
Descriptor: CMP-sialic acid transporter 1, CYTIDINE-5'-MONOPHOSPHATE
Authors:Nji, E, Gulati, A, Qureshi, A.A, Drew, D.
Deposit date:2018-10-30
Release date:2019-06-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the delivery of activated sialic acid into Golgi for sialyation.
Nat.Struct.Mol.Biol., 26, 2019
2XUT
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BU of 2xut by Molmil
Crystal structure of a proton dependent oligopeptide (POT) family transporter.
Descriptor: PROTON/PEPTIDE SYMPORTER FAMILY PROTEIN
Authors:Newstead, S, Drew, D, Cameron, A.D, Postis, V.L, Xia, X, Fowler, P.W, Ingram, J.C, Carpenter, E.P, Sansom, M.S.P, McPherson, M.J, Baldwin, S.A, Iwata, S.
Deposit date:2010-10-21
Release date:2010-12-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal Structure of a Prokaryotic Homologue of the Mammalian Oligopeptide-Proton Symporters, Pept1 and Pept2.
Embo J., 30, 2011
6I1Z
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BU of 6i1z by Molmil
Outward facing structure of apo CST
Descriptor: CMP-sialic acid transporter 1
Authors:Nji, E, Gulati, A, Qureshi, A.A, Drew, D.
Deposit date:2018-10-31
Release date:2019-06-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for the delivery of activated sialic acid into Golgi for sialyation.
Nat.Struct.Mol.Biol., 26, 2019
6RW3
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BU of 6rw3 by Molmil
The molecular basis for sugar import in malaria parasites.
Descriptor: Hexose transporter 1, alpha-D-glucopyranose, beta-D-glucopyranose
Authors:Qureshi, A, Matsuoka, R, Brock, J, Drew, D.
Deposit date:2019-06-03
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:The molecular basis for sugar import in malaria parasites.
Nature, 578, 2020
7P1J
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BU of 7p1j by Molmil
Cryo EM structure of bison NHA2 in detergent structure
Descriptor: mitochondrial sodium/hydrogen exchanger 9B2
Authors:Matsuoka, R, Fudim, R, Jung, S, Drew, D.
Deposit date:2021-07-01
Release date:2022-01-26
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
7P1I
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BU of 7p1i by Molmil
Cryo EM structure of bison NHA2 in detergent and N-terminal extension helix
Descriptor: mitochondrial sodium/hydrogen exchanger 9B2
Authors:Matsuoka, R, Fudim, R, Jung, S, Drew, D.
Deposit date:2021-07-01
Release date:2022-01-26
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
7P1K
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BU of 7p1k by Molmil
Cryo EM structure of bison NHA2 in nano disc structure
Descriptor: CHOLESTEROL HEMISUCCINATE, Phosphatidylinositol, mitochondrial sodium/hydrogen exchanger 9B2
Authors:Matsuoka, R, Fudim, R, Jung, S, Drew, D.
Deposit date:2021-07-01
Release date:2022-01-26
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
6Z3Y
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BU of 6z3y by Molmil
CryoEM structure of horse sodium/proton exchanger NHE9 in an inward-facing conformation
Descriptor: Sodium/hydrogen exchanger
Authors:Winkelmannm, I, Matsuoka, R, Meier, P, Drew, D.
Deposit date:2020-05-22
Release date:2020-11-04
Last modified:2021-03-17
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9.
Embo J., 39, 2020
4YB9
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BU of 4yb9 by Molmil
Crystal structure of the Bovine Fructose transporter GLUT5 in an open inward-facing conformation
Descriptor: Solute carrier family 2, facilitated glucose transporter member 5
Authors:Verdon, G, Kang, H.J, Iwata, S, Drew, D.
Deposit date:2015-02-18
Release date:2015-10-14
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and mechanism of the mammalian fructose transporter GLUT5.
Nature, 526, 2015
5BZ3
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BU of 5bz3 by Molmil
CRYSTAL STRUCTURE OF SODIUM PROTON ANTIPORTER NAPA IN OUTWARD-FACING CONFORMATION.
Descriptor: (2R)-2,3-DIHYDROXYPROPYL (7Z)-TETRADEC-7-ENOATE, Na(+)/H(+) antiporter
Authors:Coincon, M, Uzdavinys, P, Emmanuel, N, Cameron, A, Drew, D.
Deposit date:2015-06-11
Release date:2016-01-20
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.
Nat.Struct.Mol.Biol., 23, 2016
5BZ2
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BU of 5bz2 by Molmil
CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION
Descriptor: Na(+)/H(+) antiporter
Authors:Coincon, M, Uzdavinys, P, Cameron, A, Drew, D.
Deposit date:2015-06-11
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.
Nat.Struct.Mol.Biol., 23, 2016
3ZUX
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BU of 3zux by Molmil
Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT.
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, MERCURY (II) ION, PHOSPHATIDYLETHANOLAMINE, ...
Authors:Hu, N.-J, Iwata, S, Cameron, A.D, Drew, D.
Deposit date:2011-07-21
Release date:2011-10-12
Last modified:2023-05-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
3ZUY
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BU of 3zuy by Molmil
Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT.
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ...
Authors:Hu, N.-J, Iwata, S, Cameron, A.D, Drew, D.
Deposit date:2011-07-21
Release date:2011-10-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
4APS
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BU of 4aps by Molmil
Crystal structure of a POT family peptide transporter in an inward open conformation.
Descriptor: CADMIUM ION, DI-OR TRIPEPTIDE H+ SYMPORTER
Authors:Solcan, N, Kwok, J, Fowler, P.W, Cameron, A.D, Drew, D, Iwata, S, Newstead, S.
Deposit date:2012-04-05
Release date:2012-06-13
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Alternating Access Mechanism in the Pot Family of Oligopeptide Transporters.
Embo J., 31, 2012

 

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