Author results

1PAD
  • Download 1pad
  • View 1pad
Molmil generated image of 1pad
BINDING OF CHLOROMETHYL KETONE SUBSTRATE ANALOGUES TO CRYSTALLINE PAPAIN
Descriptor:PAPAIN, ACETYL-ALA-ALA-PHE-ALA-CHLOROMETHYLKETONE INHIBITOR
Authors:Drenth, J., Kalk, K.H., Swen, H.M.
Deposit date:1976-11-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding of chloromethyl ketone substrate analogues to crystalline papain.
Biochemistry, 15, 1976
2PAD
  • Download 2pad
  • View 2pad
Molmil generated image of 2pad
BINDING OF CHLOROMETHYL KETONE SUBSTRATE ANALOGUES TO CRYSTALLINE PAPAIN
Descriptor:PAPAIN, CYSTEINE
Authors:Drenth, J., Kalk, K.H., Swen, H.M.
Deposit date:1976-11-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding of chloromethyl ketone substrate analogues to crystalline papain.
Biochemistry, 15, 1976
4PAD
  • Download 4pad
  • View 4pad
Molmil generated image of 4pad
BINDING OF CHLOROMETHYL KETONE SUBSTRATE ANALOGUES TO CRYSTALLINE PAPAIN
Descriptor:PAPAIN, N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide
Authors:Drenth, J.
Deposit date:1976-11-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding of chloromethyl ketone substrate analogues to crystalline papain.
Biochemistry, 15, 1976
5PAD
  • Download 5pad
  • View 5pad
Molmil generated image of 5pad
BINDING OF CHLOROMETHYL KETONE SUBSTRATE ANALOGUES TO CRYSTALLINE PAPAIN
Descriptor:PAPAIN, PHQ-GLY-PHE-GLY-CHLOROMETHYLKETONE INHIBITOR
Authors:Drenth, J., Kalk, K.H., Swen, H.M.
Deposit date:1976-11-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding of chloromethyl ketone substrate analogues to crystalline papain.
Biochemistry, 15, 1976
6PAD
  • Download 6pad
  • View 6pad
Molmil generated image of 6pad
BINDING OF CHLOROMETHYL KETONE SUBSTRATE ANALOGUES TO CRYSTALLINE PAPAIN
Descriptor:PAPAIN, Nalpha-[(benzyloxy)carbonyl]-N-[(1S)-3-chloro-1-methyl-2-oxopropyl]-L-phenylalaninamide
Authors:Drenth, J., Kalk, K.H., Swen, H.M.
Deposit date:1976-11-01
Release date:1977-04-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding of chloromethyl ketone substrate analogues to crystalline papain.
Biochemistry, 15, 1976
2SBT
  • Download 2sbt
  • View 2sbt
Molmil generated image of 2sbt
A COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SUBTILISIN BPN AND SUBTILISIN NOVO
Descriptor:SUBTILISIN NOVO, ACETONE
Authors:Drenth, J., Hol, W.G.J., Jansonius, J.N., Koekoek, R.
Deposit date:1976-09-07
Release date:1976-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo.
Cold Spring Harbor Symp.Quant.Biol., 36, 1972
1PBE
  • Download 1pbe
  • View 1pbe
Molmil generated image of 1pbe
CRYSTAL STRUCTURE OF THE P-HYDROXYBENZOATE HYDROXYLASE-SUBSTRATE COMPLEX REFINED AT 1.9 ANGSTROMS RESOLUTION. ANALYSIS OF THE ENZYME-SUBSTRATE AND ENZYME-PRODUCT COMPLEXES
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Schreuder, H.A., Hol, W.G.J., Drenth, J.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the p-hydroxybenzoate hydroxylase-substrate complex refined at 1.9 A resolution. Analysis of the enzyme-substrate and enzyme-product complexes.
J.Mol.Biol., 208, 1989
2PHH
  • Download 2phh
  • View 2phh
Molmil generated image of 2phh
THE COENZYME ANALOGUE ADENOSINE 5-DIPHOSPHORIBOSE DISPLACES FAD IN THE ACTIVE SITE OF P-HYDROXYBENZOATE HYDROXYLASE. AN X-RAY CRYSTALLOGRAPHIC INVESTIGATION
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, ADENOSINE-5-DIPHOSPHORIBOSE, P-HYDROXYBENZOIC ACID
Authors:Van Derlaan, J.M., Drenth, J., Hol, W.G.J.
Deposit date:1989-06-19
Release date:1990-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation.
Biochemistry, 28, 1989
1PHH
  • Download 1phh
  • View 1phh
Molmil generated image of 1phh
CRYSTAL STRUCTURE OF P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH ITS REACTION PRODUCT 3,4-DIHYDROXYBENZOATE
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 3,4-DIHYDROXYBENZOIC ACID
Authors:Schreuder, H.A., Drenth, J.
Deposit date:1987-11-04
Release date:1988-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate.
J.Mol.Biol., 199, 1988
3BP2
  • Download 3bp2
  • View 3bp2
Molmil generated image of 3bp2
ROLE OF THE N-TERMINUS IN THE INTERACTION OF PANCREATIC PHOSPHOLIPASE A2 WITH AGGREGATED SUBSTRATES. PROPERTIES AND CRYSTAL STRUCTURE OF TRANSAMINATED PHOSPHOLIPASE A2
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION
Authors:Dijkstra, B.W., Drenth, J.
Deposit date:1983-06-27
Release date:1983-09-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Role of the N-terminus in the interaction of pancreatic phospholipase A2 with aggregated substrates. Properties and crystal structure of transaminated phospholipase A2
Biochemistry, 23, 1984
3P2P
  • Download 3p2p
  • View 3p2p
Molmil generated image of 3p2p
ENHANCED ACTIVITY AND ALTERED SPECIFICITY OF PHOSPHOLIPASE A2 BY DELETION OF A SURFACE LOOP
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION
Authors:Dijkstra, B.W., Thunnissen, M.M.G.M., Kalk, K.H., Drenth, J.
Deposit date:1989-11-29
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Enhanced activity and altered specificity of phospholipase A2 by deletion of a surface loop.
Science, 244, 1989
5P2P
  • Download 5p2p
  • View 5p2p
Molmil generated image of 5p2p
X-RAY STRUCTURE OF PHOSPHOLIPASE A2 COMPLEXED WITH A SUBSTRATE-DERIVED INHIBITOR
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION, PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER
Authors:Dijkstra, B.W., Thunnissen, M.M.G.M., Kalk, K.H., Drenth, J.
Deposit date:1990-09-01
Release date:1991-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor.
Nature, 347, 1990
9PAP
  • Download 9pap
  • View 9pap
Molmil generated image of 9pap
STRUCTURE OF PAPAIN REFINED AT 1.65 ANGSTROMS RESOLUTION
Descriptor:PAPAIN, METHANOL
Authors:Kamphuis, I.G., Drenth, J.
Deposit date:1986-03-31
Release date:1986-10-24
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of papain refined at 1.65 A resolution
J.Mol.Biol., 179, 1984
1P2P
  • Download 1p2p
  • View 1p2p
Molmil generated image of 1p2p
STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 AT 2.6 ANGSTROMS RESOLUTION AND COMPARISON WITH BOVINE PHOSPHOLIPASE A2
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION
Authors:Dijkstra, B.W., Renetseder, R., Kalk, K.H., Hol, W.G.J., Drenth, J.
Deposit date:1983-06-27
Release date:1983-09-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of porcine pancreatic phospholipase A2 at 2.6 A resolution and comparison with bovine phospholipase A2.
J.Mol.Biol., 168, 1983
1BP2
  • Download 1bp2
  • View 1bp2
Molmil generated image of 1bp2
STRUCTURE OF BOVINE PANCREATIC PHOSPHOLIPASE A2 AT 1.7 ANGSTROMS RESOLUTION
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Dijkstra, B.W., Kalk, K.H., Hol, W.G.J., Drenth, J.
Deposit date:1981-04-06
Release date:1981-05-21
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of bovine pancreatic phospholipase A2 at 1.7A resolution.
J.Mol.Biol., 147, 1981
2BP2
  • Download 2bp2
  • View 2bp2
Molmil generated image of 2bp2
THE STRUCTURE OF BOVINE PANCREATIC PROPHOSPHOLIPASE A2 AT 3.0 ANGSTROMS RESOLUTION
Descriptor:PHOSPHOLIPASE A2
Authors:Dijkstra, B.W., Vannes, G.J.H., Kalk, K.H., Brandenburg, N.P., Hol, W.G.J., Drenth, J.
Deposit date:1981-06-05
Release date:1981-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of Bovine Pancreatic Prophospholipase A2 at 3.0 Angstroms Resolution
Acta Crystallogr.,Sect.B, 38, 1982
2PHI
  • Download 2phi
  • View 2phi
Molmil generated image of 2phi
A LARGE CONFORMATIONAL CHANGE IS FOUND IN THE CRYSTAL STRUCTURE OF THE PORCINE PANCREATIC PHOSPHOLIPASE A2 POINT MUTANT F63V
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION
Authors:Dijkstra, B.W., Thunnissen, M.M.G.M., Kalk, K.H., Drenth, J.
Deposit date:1993-04-08
Release date:1993-07-15
Last modified:2012-01-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a porcine pancreatic phospholipase A2 mutant. A large conformational change caused by the F63V point mutation.
J.Mol.Biol., 232, 1993
1PBB
  • Download 1pbb
  • View 1pbb
Molmil generated image of 1pbb
CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 2,4-DIHYDROXYBENZOIC ACID
Authors:Schreuder, H.A., Mattevi, A., Hol, W.G.J.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
1PBC
  • Download 1pbc
  • View 1pbc
Molmil generated image of 1pbc
CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 2-HYDROXY-4-AMINOBENZOIC ACID
Authors:Schreuder, H.A., Van Der Bolt, F.J.T., Van Berkel, W.J.H.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
1PBD
  • Download 1pbd
  • View 1pbd
Molmil generated image of 1pbd
CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 4-AMINOBENZOIC ACID
Authors:Schreuder, H.A., Mattevi, A., Hol, W.G.J.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
1PBF
  • Download 1pbf
  • View 1pbf
Molmil generated image of 1pbf
CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, 2-HYDROXY-4-AMINOBENZOIC ACID
Authors:Schreuder, H.A., Van Der Bolt, F.J.T., Van Berkel, W.J.H.
Deposit date:1994-07-06
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
1PDH
  • Download 1pdh
  • View 1pdh
Molmil generated image of 1pdh
CRYSTAL STRUCTURE OF P-HYDROXYBENZOATE HYDROXYLASE RECONSTITUTED WITH THE MODIFIED FAD PRESENT IN ALCOHOL OXIDASE FROM METHYLOTROPHIC YEASTS: EVIDENCE FOR AN ARABINOFLAVIN
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, ARABINO-FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Schreuder, H.A., Eppink, M.H.M., Van Berkel, W.J.H.
Deposit date:1994-12-01
Release date:1995-03-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of p-hydroxybenzoate hydroxylase reconstituted with the modified FAD present in alcohol oxidase from methylotrophic yeasts: evidence for an arabinoflavin.
Protein Sci., 3, 1994
1BF3
  • Download 1bf3
  • View 1bf3
Molmil generated image of 1bf3
P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND ARG 42 REPLACED BY LYS (R42K), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1998-05-26
Release date:1998-08-12
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Lys42 and Ser42 variants of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens reveal that Arg42 is essential for NADPH binding.
Eur.J.Biochem., 253, 1998
1BGJ
  • Download 1bgj
  • View 1bgj
Molmil generated image of 1bgj
P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND HIS 162 REPLACED BY ARG (H162R), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1998-05-29
Release date:1998-08-12
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Interdomain binding of NADPH in p-hydroxybenzoate hydroxylase as suggested by kinetic, crystallographic and modeling studies of histidine 162 and arginine 269 variants.
J.Biol.Chem., 273, 1998
1BGN
  • Download 1bgn
  • View 1bgn
Molmil generated image of 1bgn
P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND ARG 269 REPLACED BY THR (R269T), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor:P-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M., Schreuder, H.A., Van Berkel, W.J.H.
Deposit date:1998-05-29
Release date:1998-08-12
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain binding of NADPH in p-hydroxybenzoate hydroxylase as suggested by kinetic, crystallographic and modeling studies of histidine 162 and arginine 269 variants.
J.Biol.Chem., 273, 1998
<123>