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2FFL
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BU of 2ffl by Molmil
Crystal Structure of Dicer from Giardia intestinalis
Descriptor: Dicer, MANGANESE (II) ION
Authors:Doudna, J.A, MacRae, I.J, Adams, P.D.
Deposit date:2005-12-19
Release date:2006-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Structural Basis of Double-Stranded RNA Processing by Dicer
Science, 311, 2006
2QVW
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BU of 2qvw by Molmil
Structure of Giardia Dicer refined against twinned data
Descriptor: GLP_546_48378_50642, MANGANESE (II) ION
Authors:Doudna, J.A, MacRae, I.J.
Deposit date:2007-08-09
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:An unusual case of pseudo-merohedral twinning in orthorhombic crystals of Dicer
Acta Crystallogr.,Sect.D, 63, 2007
8VXY
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BU of 8vxy by Molmil
Structure of HamA(E138A,K140A)B-plasmid DNA complex from the Escherichia coli Hachiman defense system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, HamA, HamB, ...
Authors:Tuck, O.T, Hu, J.J, Doudna, J.A.
Deposit date:2024-02-06
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
8VXC
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BU of 8vxc by Molmil
Structure of HamB-DNA complex, conformation 2, from the Escherichia coli Hachiman defense system
Descriptor: DNA (40-MER), HamB
Authors:Tuck, O.T, Doudna, J.A.
Deposit date:2024-02-04
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
8VX9
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BU of 8vx9 by Molmil
Structure of HamAB apo complex from the Escherichia coli Hachiman defense system
Descriptor: HamA, HamB
Authors:Tuck, O.T, Doudna, J.A.
Deposit date:2024-02-03
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
8VXA
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BU of 8vxa by Molmil
Structure of HamB-DNA complex, conformation 1, from the Escherichia coli Hachiman defense system
Descriptor: DNA (40-MER), HamB
Authors:Tuck, O.T, Doudna, J.A.
Deposit date:2024-02-03
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
3FRX
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BU of 3frx by Molmil
Crystal Structure of the Yeast Orthologue of RACK1, Asc1.
Descriptor: Guanine nucleotide-binding protein subunit beta-like protein, MANGANESE (II) ION
Authors:Coyle, S.M, Gilbert, W.V, Doudna, J.A.
Deposit date:2009-01-08
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Direct link between RACK1 function and localization at the ribosome in vivo
Mol.Cell.Biol., 29, 2009
1GID
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BU of 1gid by Molmil
CRYSTAL STRUCTURE OF A GROUP I RIBOZYME DOMAIN: PRINCIPLES OF RNA PACKING
Descriptor: COBALT HEXAMMINE(III), MAGNESIUM ION, P4-P6 RNA RIBOZYME DOMAIN
Authors:Cate, J.H, Gooding, A.R, Podell, E, Zhou, K, Golden, B.L, Kundrot, C.E, Cech, T.R, Doudna, J.A.
Deposit date:1996-08-22
Release date:1996-12-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a group I ribozyme domain: principles of RNA packing.
Science, 273, 1996
6VPC
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BU of 6vpc by Molmil
Structure of the SpCas9 DNA adenine base editor - ABE8e
Descriptor: CRISPR-associated endonuclease Cas9, Cas9 (SpCas9) single-guide RNA (sgRNA), DNA non-target strand (NTS), ...
Authors:Knott, G.J, Lapinaite, A, Doudna, J.A.
Deposit date:2020-02-03
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:DNA capture by a CRISPR-Cas9-guided adenine base editor.
Science, 369, 2020
3T4B
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BU of 3t4b by Molmil
Crystal Structure of the HCV IRES pseudoknot domain
Descriptor: HCV IRES pseudoknot domain plus crystallization module, NICKEL (II) ION
Authors:Berry, K.E, Waghray, S, Mortimer, S.A, Bai, Y, Doudna, J.A.
Deposit date:2011-07-25
Release date:2011-10-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning.
Structure, 19, 2011
5K4D
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BU of 5k4d by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 3
Descriptor: Eukaryotic translation initiation factor 3 subunit D
Authors:Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
Deposit date:2016-05-20
Release date:2016-07-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
6P7M
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BU of 6p7m by Molmil
Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (1:2 complex)
Descriptor: Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ...
Authors:Knott, G.J, Liu, J.J, Doudna, J.A.
Deposit date:2019-06-06
Release date:2019-08-21
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
Elife, 8, 2019
6P7N
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BU of 6p7n by Molmil
Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (2:2 complex)
Descriptor: Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ...
Authors:Knott, G.J, Liu, J.J, Doudna, J.A.
Deposit date:2019-06-06
Release date:2019-08-21
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
Elife, 8, 2019
7S37
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BU of 7s37 by Molmil
Cas9:sgRNA (S. pyogenes) in the open-protein conformation
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Single-guide RNA
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-04
Release date:2022-04-20
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7S36
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BU of 7s36 by Molmil
Cas9:sgRNA:DNA (S. pyogenes) with 0 RNA:DNA base pairs, closed-protein/bent-DNA conformation
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-04
Release date:2022-04-20
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7S38
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BU of 7s38 by Molmil
Cas9:sgRNA:DNA (S. pyogenes) forming a 3-base-pair R-loop
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-04
Release date:2022-04-20
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7S3H
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BU of 7s3h by Molmil
Cas9:sgRNA:DNA (S. pyogenes) with 0 RNA:DNA base pairs, open-protein/linear-DNA conformation
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-06
Release date:2022-04-20
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7THB
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BU of 7thb by Molmil
Crystal structure of an RNA-5'/DNA-3' strand exchange junction
Descriptor: DNA (5'-D(*GP*AP*TP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*TP*AP*AP*GP*CP*AP*GP*CP*AP*TP*C)-3'), RNA (5'-R(*AP*GP*CP*UP*UP*AP*C)-3')
Authors:Cofsky, J.C, Knott, G.J, Gee, C.L, Doudna, J.A.
Deposit date:2022-01-10
Release date:2022-04-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal structure of an RNA/DNA strand exchange junction.
Plos One, 17, 2022
4TXY
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BU of 4txy by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog
Descriptor: Cyclic AMP-GMP synthase, MAGNESIUM ION
Authors:Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
Deposit date:2014-07-07
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.0001 Å)
Cite:Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
4TY0
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BU of 4ty0 by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG
Descriptor: ACETATE ION, Cyclic AMP-GMP synthase, MAGNESIUM ION, ...
Authors:Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
Deposit date:2014-07-07
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
4TXZ
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BU of 4txz by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP
Descriptor: Cyclic AMP-GMP synthase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
Authors:Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
Deposit date:2014-07-07
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
5I4A
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BU of 5i4a by Molmil
X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA
Descriptor: Argonaute protein, RNA (5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*U)-3')
Authors:Doxzen, K.W, Kaya, E, Knoll, K.R, Wilson, R.C, Strutt, S.C, Kranzusch, P.J, Doudna, J.A.
Deposit date:2016-02-11
Release date:2016-03-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:A bacterial Argonaute with noncanonical guide RNA specificity.
Proc.Natl.Acad.Sci.USA, 113, 2016
5K4C
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BU of 5k4c by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2
Descriptor: Eukaryotic translation initiation factor 3 subunit D, GLYCEROL
Authors:Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
Deposit date:2016-05-20
Release date:2016-07-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
5K4B
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BU of 5k4b by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 1
Descriptor: CHLORIDE ION, Eukaryotic translation initiation factor 3 subunit D
Authors:Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
Deposit date:2016-05-20
Release date:2016-07-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
2OIH
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BU of 2oih by Molmil
Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+
Descriptor: HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
Deposit date:2007-01-11
Release date:2007-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007

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PDB entries from 2024-03-27

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