Author results

2FFL
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CRYSTAL STRUCTURE OF DICER FROM GIARDIA INTESTINALIS
Descriptor:Dicer, MANGANESE (II) ION
Authors:Doudna, J.A., MacRae, I.J., Adams, P.D.
Deposit date:2005-12-19
Release date:2006-01-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Structural Basis of Double-Stranded RNA Processing by Dicer
Science, 311, 2006
2QVW
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STRUCTURE OF GIARDIA DICER REFINED AGAINST TWINNED DATA
Descriptor:GLP_546_48378_50642, MANGANESE (II) ION
Authors:Doudna, J.A., MacRae, I.J.
Deposit date:2007-08-09
Release date:2007-09-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:An unusual case of pseudo-merohedral twinning in orthorhombic crystals of Dicer
Acta Crystallogr.,Sect.D, 63, 2007
1GID
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CRYSTAL STRUCTURE OF A GROUP I RIBOZYME DOMAIN: PRINCIPLES OF RNA PACKING
Descriptor:P4-P6 RNA RIBOZYME DOMAIN, MAGNESIUM ION, COBALT HEXAMMINE(III)
Authors:Cate, J.H., Gooding, A.R., Podell, E., Zhou, K., Golden, B.L., Kundrot, C.E., Cech, T.R., Doudna, J.A.
Deposit date:1996-08-22
Release date:1996-12-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a group I ribozyme domain: principles of RNA packing.
Science, 273, 1996
1DRZ
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U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX
Descriptor:RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), MAGNESIUM ION, ...
Authors:Ferre-D'Amare, A.R., Zhou, K., Doudna, J.A.
Deposit date:1998-09-01
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a hepatitis delta virus ribozyme.
Nature, 395, 1998
1HQ1
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STRUCTURAL AND ENERGETIC ANALYSIS OF RNA RECOGNITION BY A UNIVERSALLY CONSERVED PROTEIN FROM THE SIGNAL RECOGNITION PARTICLE
Descriptor:4.5S RNA DOMAIN IV, SIGNAL RECOGNITION PARTICLE PROTEIN, MAGNESIUM ION, ...
Authors:Batey, R.T., Sagar, M.B., Doudna, J.A.
Deposit date:2000-12-13
Release date:2001-01-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle.
J.Mol.Biol., 307, 2001
1KH6
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CRYSTAL STRUCTURE OF AN RNA TERTIARY DOMAIN ESSENTIAL TO HCV IRES-MEDIATED TRANSLATION INITIATION.
Descriptor:JIIIabc
Authors:Kieft, J.S., Zhou, K., Grech, A., Jubin, R., Doudna, J.A.
Deposit date:2001-11-29
Release date:2002-04-26
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation.
Nat.Struct.Biol., 9, 2002
1KXK
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CRYSTAL STRUCTURE OF A RNA MOLECULE CONTAINING DOMAIN 5 AND 6 OF THE YEAST AI5G GROUP II SELF-SPLICING INTRON
Descriptor:ai5g group II Self-splicing intron, MAGNESIUM ION
Authors:Zhang, L., Doudna, J.A.
Deposit date:2002-01-31
Release date:2002-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into group II intron catalysis and branch-site selection.
Science, 295, 2002
1L8V
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CRYSTAL STRUCTURE OF A MUTANT (C109G,G212C) P4-P6 DOMAIN OF THE GROUP I INTRON FROM TETRAHYMENA THERMOPHILIA
Descriptor:P4-P6 RNA ribozyme domain, MAGNESIUM ION
Authors:Battle, D.J., Doudna, J.A.
Deposit date:2002-03-21
Release date:2002-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Specificity of RNA-RNA Helix Recognition
Proc.Natl.Acad.Sci.USA, 99, 2002
1SJ3
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HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH MG2+ BOUND
Descriptor:precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A, MAGNESIUM ION
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H., Doudna, J.A.
Deposit date:2004-03-02
Release date:2004-05-18
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
Nature, 429, 2004
1SJ4
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CRYSTAL STRUCTURE OF A C75U MUTANT HEPATITIS DELTA VIRUS RIBOZYME PRECURSOR, IN CU2+ SOLUTION
Descriptor:precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H., Doudna, J.A.
Deposit date:2004-03-02
Release date:2004-05-18
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
Nature, 429, 2004
1SJF
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, IN COBALT HEXAMMINE SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, COBALT HEXAMMINE(III)
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A conformational switch controls hepatitis delta virus ribozyme catalysis.
Nature, 429, 2004
1VBX
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, IN EDTA SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBY
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, AND MN2+ BOUND
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, MANGANESE (II) ION, ...
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBZ
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, IN BA2+ SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, BARIUM ION
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC0
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, IN IMIDAZOLE AND SR2+ SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, STRONTIUM ION
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC5
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CRYSTAL STRUCTURE OF THE WILD TYPE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, IN EDTA SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, SODIUM ION
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC6
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRODUCT WITH C75U MUTAION, CLEAVED IN IMIDAZOLE AND MG2+ SOLUTIONS
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, MAGNESIUM ION
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
2OIH
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HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR WITH C75U MUTATION AND BOUND TO MONOVALENT CATION TL+
Descriptor:HDV ribozyme, U1 small nuclear ribonucleoprotein A, THALLIUM (I) ION
Authors:Ke, A., Ding, F., Batchelor, J.D., Doudna, J.A.
Deposit date:2007-01-11
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
2OJ3
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HEPATITIS DELTA VIRUS RIBOZYME PRECURSOR STRUCTURE, WITH C75U MUTATION, BOUND TO TL+ AND COBALT HEXAMMINE (CO(NH3)63+)
Descriptor:HDV RIBOZYME, U1 small nuclear ribonucleoprotein A, COBALT HEXAMMINE(III), ...
Authors:Ke, A., Ding, F., Batchelor, J.D., Doudna, J.A.
Deposit date:2007-01-12
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
2X04
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CRYSTAL STRUCTURE OF THE PABC-TNRC6C COMPLEX
Descriptor:POLYADENYLATE-BINDING PROTEIN 1, TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN, SULFATE ION
Authors:Jinek, M., Fabian, M.R., Coyle, S.M., Sonenberg, N., Doudna, J.A.
Deposit date:2009-12-04
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural Insights Into the Human Gw182-Pabc Interaction in Microrna-Mediated Deadenylation
Nat.Struct.Mol.Biol., 17, 2010
2XLI
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CRYSTAL STRUCTURE OF THE CSY4-CRRNA COMPLEX, MONOCLINIC FORM
Descriptor:CSY4 ENDORIBONUCLEASE, 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3'
Authors:Haurwitz, R.E., Jinek, M., Wiedenheft, B., Zhou, K., Doudna, J.A.
Deposit date:2010-07-20
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease.
Science, 329, 2010
2XLJ
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CRYSTAL STRUCTURE OF THE CSY4-CRRNA COMPLEX, HEXAGONAL FORM
Descriptor:CSY4 ENDORIBONUCLEASE, 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3'
Authors:Haurwitz, R.E., Jinek, M., Wiedenheft, B., Zhou, K., Doudna, J.A.
Deposit date:2010-07-20
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease.
Science, 329, 2010
2XLK
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CRYSTAL STRUCTURE OF THE CSY4-CRRNA COMPLEX, ORTHORHOMBIC FORM
Descriptor:CSY4 ENDORIBONUCLEASE, 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3'
Authors:Haurwitz, R.E., Jinek, M., Wiedenheft, B., Zhou, K., Doudna, J.A.
Deposit date:2010-07-21
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease.
Science, 329, 2010
2XXA
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THE CRYSTAL STRUCTURE OF THE SIGNAL RECOGNITION PARTICLE (SRP) IN COMPLEX WITH ITS RECEPTOR(SR)
Descriptor:SIGNAL RECOGNITION PARTICLE PROTEIN, SRP RECEPTOR FTSY, 4.5S RNA, ...
Authors:Ataide, S.F., Schmitz, N., Shen, K., Ke, A., Shan, S., Doudna, J.A., Ban, N.
Deposit date:2010-11-09
Release date:2011-03-02
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (3.94 Å)
Cite:The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor.
Science, 331, 2011
2Y35
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CRYSTAL STRUCTURE OF XRN1-SUBSTRATE COMPLEX
Descriptor:LD22664P, DT11 (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP)-3', MAGNESIUM ION
Authors:Jinek, M., Coyle, S.M., Doudna, J.A.
Deposit date:2010-12-18
Release date:2011-03-16
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Coupled 5' Nucleotide Recognition and Processivity in Xrn1-Mediated Mrna Decay.
Mol.Cell, 41, 2011