Author results

1ITM
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ANALYSIS OF THE SOLUTION STRUCTURE OF HUMAN INTERLEUKIN 4 DETERMINED BY HETERONUCLEAR THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE TECHNIQUES
分子名称:INTERLEUKIN-4
著者Redfield, C., Smith, L.J., Boyd, J., Lawrence, G.M.P., Edwards, R.G., Gershater, C.J., Smith, R.A.G., Dobson, C.M.
登録日1994-02-28
公開日1994-05-31
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Analysis of the solution structure of human interleukin-4 determined by heteronuclear three-dimensional nuclear magnetic resonance techniques.
J.Mol.Biol., 238, 1994
1ITL
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HUMAN INTERLEUKIN 4: THE SOLUTION STRUCTURE OF A FOUR-HELIX-BUNDLE PROTEIN
分子名称:INTERLEUKIN-4
著者Smith, L.J., Redfield, C., Boyd, J., Lawrence, G.M.P., Edwards, R.G., Smith, R.A.G., Dobson, C.M.
登録日1992-02-08
公開日1993-04-15
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Human interleukin 4. The solution structure of a four-helix bundle protein.
J.Mol.Biol., 224, 1992
1KDU
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SEQUENTIAL 1H NMR ASSIGNMENTS AND SECONDARY STRUCTURE OF THE KRINGLE DOMAIN FROM UROKINASE
分子名称:PLASMINOGEN ACTIVATOR
著者Li, X., Bokman, A.M., Llinas, M., Smith, R.A.G., Dobson, C.M.
登録日1993-07-15
公開日1993-10-31
最終更新日2012-08-01
実験手法SOLUTION NMR
主引用文献Solution structure of the kringle domain from urokinase-type plasminogen activator.
J.Mol.Biol., 235, 1994
1RVS
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STRUCTURE OF TRANSTHYRETIN IN AMYLOID FIBRILS DETERMINED BY SOLID-STATE MAGIC ANGLE SPINNING NMR
分子名称:Transthyretin
著者Jaroniec, C.P., Macphee, C.E., Bajaj, V.S., Mcmahon, M.T., Dobson, C.M., Griffin, R.G.
登録日2003-12-14
公開日2004-01-20
最終更新日2011-07-13
実験手法SOLID-STATE NMR
主引用文献High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy
Proc.Natl.Acad.Sci.USA, 101, 2004
2NBT
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NEURONAL BUNGAROTOXIN, NMR, 10 STRUCTURES
分子名称:NEURONAL BUNGAROTOXIN
著者Oswald, R.E., Sutcliffe, M.J., Bamberger, M., Loring, R.H., Braswell, E., Dobson, C.M.
登録日1997-10-29
公開日1998-03-11
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of neuronal bungarotoxin determined by two-dimensional NMR spectroscopy: calculation of tertiary structure using systematic homologous model building, dynamical simulated annealing, and restrained molecular dynamics.
Biochemistry, 31, 1992
1BBA
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SEQUENCE-SPECIFIC 1H NMR ASSIGNMENTS AND SOLUTION STRUCTURE OF BOVINE PANCREATIC POLYPEPTIDE
分子名称:BOVINE PANCREATIC POLYPEPTIDE
著者Li, X., Sutcliffe, M.J., Schwartz, T.W., Dobson, C.M.
登録日1992-03-10
公開日1993-10-31
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Sequence-specific 1H NMR assignments and solution structure of bovine pancreatic polypeptide.
Biochemistry, 31, 1992
1E8L
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NMR SOLUTION STRUCTURE OF HEN LYSOZYME
分子名称:LYSOZYME
著者Schwalbe, H., Grimshaw, S.B., Spencer, A., Buck, M., Boyd, J., Dobson, C.M., Redfield, C., Smith, L.J.
登録日2000-09-27
公開日2000-10-09
最終更新日2018-01-24
実験手法SOLUTION NMR
主引用文献A refined solution structure of hen lysozyme determined using residual dipolar coupling data.
Protein Sci., 10, 2001
1LMW
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LMW U-PA STRUCTURE COMPLEXED WITH EGRCMK (GLU-GLY-ARG CHLOROMETHYL KETONE)
分子名称:UROKINASE-TYPE PLASMINOGEN ACTIVATOR, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide
著者Spraggon, G.S., Phillips, C., Nowak, U.K., Ponting, C.P., Saunders, D., Dobson, C.M., Stuart, D.I., Jones, E.Y.
登録日1995-07-26
公開日1996-01-29
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of the catalytic domain of human urokinase-type plasminogen activator.
Structure, 3, 1995
1OP9
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COMPLEX OF HUMAN LYSOZYME WITH CAMELID VHH HL6 ANTIBODY FRAGMENT
分子名称:HL6 camel VHH fragment, Lysozyme C
著者Dumoulin, M., Last, A.M., Desmyter, A., Decanniere, K., Canet, D., Larsson, G., Spencer, A., Archer, D.B., Sasse, J., Muyldermans, S., Wyns, L., Redfield, C., Matagne, A., Robinson, C.V., Dobson, C.M.
登録日2003-03-05
公開日2003-10-14
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme
Nature, 424, 2003
1S9Z
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SYNTHETIC 17 AMINO ACID LONG PEPTIDE THAT FORMS A NATIVE-LIKE COILED-COIL AT AMBIENT TEMPERATURE AND AGGREGATES INTO AMYLOID-LIKE FIBRILS AT HIGHER TEMPERATURES.
分子名称:SYNTHETIC COILED-COIL PEPTIDE, SODIUM ION, ZINC ION
著者Kammerer, R.A., Kostrewa, D., Zurdo, J., Detken, A., Garcia-Echeverria, C., Green, J.D., Muller, S.A., Meier, B.H., Winkler, F.K., Dobson, C.M., Steinmetz, M.O.
登録日2004-02-06
公開日2004-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Exploring amyloid formation by a de novo design
Proc.Natl.Acad.Sci.USA, 101, 2004
1W08
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STRUCTURE OF T70N HUMAN LYSOZYME
分子名称:LYSOZYME, CHLORIDE ION
著者Johnson, R., Christodoulou, J., Luisi, B., Dumoulin, M., Caddy, G., Alcocer, M., Murtagh, G., Archer, D.B., Dobson, C.M.
登録日2004-06-02
公開日2004-06-10
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Rationalising Lysozyme Amyloidosis: Insights from the Structure and Solution Dynamics of T70N Lysozyme.
J.Mol.Biol., 352, 2005
1XQQ
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SIMULTANEOUS DETERMINATION OF PROTEIN STRUCTURE AND DYNAMICS
分子名称:ubiquitin
著者Lindorff-Larsen, K., Best, R.B., DePristo, M.A., Vendruscolo, M., Dobson, C.M.
登録日2004-10-13
公開日2005-02-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Simultaneous determination of protein structure and dynamics
Nature, 433, 2005
2AAO
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REGULATORY APPARATUS OF CALCIUM DEPENDENT PROTEIN KINASE FROM ARABIDOPSIS THALIANA
分子名称:Calcium-dependent protein kinase, isoform AK1, CALCIUM ION
著者Chandran, V., Stollar, E.J., Lindorff-Larsen, K., Harper, J.F., Chazin, W.J., Dobson, C.M., Luisi, B.F., Christodoulou, J.
登録日2005-07-13
公開日2005-12-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition.
J.Mol.Biol., 357, 2006
2K0E
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A COUPLED EQUILIBRIUM SHIFT MECHANISM IN CALMODULIN-MEDIATED SIGNAL TRANSDUCTION
分子名称:Calmodulin, CALCIUM ION
著者Gsponer, J., Christodoulou, J., Cavalli, A., Bui, J.M., Richter, B., Dobson, C.M., Vendruscolo, M.
登録日2008-02-02
公開日2008-06-10
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
Structure, 16, 2008
2K0F
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CALMODULIN COMPLEXED WITH CALMODULIN-BINDING PEPTIDE FROM SMOOTH MUSCLE MYOSIN LIGHT CHAIN KINASE
分子名称:calmodulin, 19-mer peptide from Myosin light chain kinase, CALCIUM ION
著者Gsponer, J., Christodoulou, J., Cavalli, A., Bui, J.M., Richter, B., Dobson, C.M., Vendruscolo, M.
登録日2008-02-02
公開日2008-06-10
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
Structure, 16, 2008
2M5K
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ATOMIC-RESOLUTION STRUCTURE OF A DOUBLET CROSS-BETA AMYLOID FIBRIL
分子名称:Transthyretin
著者Fitzpatrick, A.W.P., Debelouchina, G.T., Bayro, M.J., Clare, D.K., Caporini, M.A., Bajaj, V.S., Jaroniec, C.P., Wang, L., Ladizhansky, V., Muller, S., MacPhee, C.E., Waudby, C.A., Mott, H.R., de Simone, A., Knowles, T.P.J., Saibil, H.R., Vendruscolo, M., Orlova, E.V., Griffin, R.G., Dobson, C.M.
登録日2013-02-27
公開日2013-12-04
最終更新日2018-07-18
実験手法SOLID-STATE NMR (12.7 Å), ELECTRON MICROSCOPY
主引用文献Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M5M
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ATOMIC-RESOLUTION STRUCTURE OF A TRIPLET CROSS-BETA AMYLOID FIBRIL
分子名称:Transthyretin
著者Fitzpatrick, A.W.P., Debelouchina, G.T., Bayro, M.J., Clare, D.K., Caporini, M.A., Bajaj, V.S., Jaroniec, C.P., Wang, L., Ladizhansky, V., Muller, S., MacPhee, C.E., Waudby, C.A., Mott, H.R., de Simone, A., Knowles, T.P.J., Saibil, H.R., Vendruscolo, M., Orlova, E.V., Griffin, R.G., Dobson, C.M.
登録日2013-02-27
公開日2013-12-04
最終更新日2018-07-18
実験手法SOLID-STATE NMR (12.2 Å), ELECTRON MICROSCOPY
主引用文献Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M5N
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ATOMIC-RESOLUTION STRUCTURE OF A CROSS-BETA PROTOFILAMENT
分子名称:Transthyretin
著者Fitzpatrick, A.W.P., Debelouchina, G.T., Bayro, M.J., Clare, D.K., Caporini, M.A., Bajaj, V.S., Jaroniec, C.P., Wang, L., Ladizhansky, V., Muller, S., MacPhee, C.E., Waudby, C.A., Mott, H.R., de Simone, A., Knowles, T.P.J., Saibil, H.R., Vendruscolo, M., Orlova, E.V., Griffin, R.G., Dobson, C.M.
登録日2013-02-27
公開日2013-07-17
実験手法SOLID-STATE NMR
主引用文献Atomic structure and hierarchical assembly of a cross-{beta} amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
2N62
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DDFLN5+110
分子名称:gelation factor, secretion monitor chimera
著者Cabrita, L.D., Cassaignau, A.M.E., Launay, H.M.M., Waudby, C.A., Camilloni, C., Robertson, A.L., Wang, X., Wlodarski, T., Wentink, A.S., Vendruscolo, M., Dobson, C.M., Christodoulou, J.
登録日2015-08-10
公開日2016-03-02
最終更新日2016-04-20
実験手法SOLUTION NMR
主引用文献A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.
Nat.Struct.Mol.Biol., 23, 2016
2X6M
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STRUCTURE OF A SINGLE DOMAIN CAMELID ANTIBODY FRAGMENT IN COMPLEX WITH A C-TERMINAL PEPTIDE OF ALPHA-SYNUCLEIN
分子名称:HEAVY CHAIN VARIABLE DOMAIN FROM DROMEDARY, ALPHA-SYNUCLEIN PEPTIDE
著者DeGenst, E., Guilliams, T., Wellens, J., O'Day, E.M., Waudby, C.A., Meehan, S., Dumoulin, M., Hsu, S.-T.D., Cremades, N., Verschueren, K.H.G., Pardon, E., Wyns, L., Steyaert, J., Christodoulou, J., Dobson, C.M.
登録日2010-02-18
公開日2010-06-23
最終更新日2017-03-29
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structure and Properties of a Complex of Alpha-Synuclein and a Single-Domain Camelid Antibody.
J.Mol.Biol., 402, 2010
3ZPK
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ATOMIC-RESOLUTION STRUCTURE OF A QUADRUPLET CROSS-BETA AMYLOID FIBRIL
分子名称:TRANSTHYRETIN
著者Fitzpatrick, A.w.P., Debelouchina, G.T., Bayro, M.J., Clare, D.K., Caporini, M.A., Bajaj, V.S., Jaroniec, C.P., Wang, L., Ladizhansky, V., Muller, S.A., MacPhee, C.E., Waudby, C.A., Mott, H.R., de Simone, A., Knowles, T.P.J., Saibil, H.R., Vendruscolo, M., Orlova, E.V., Griffin, R.G., Dobson, C.M.
登録日2013-02-28
公開日2013-12-04
最終更新日2018-03-21
実験手法SOLID-STATE NMR, ELECTRON MICROSCOPY
主引用文献Atomic Structure and Hierarchical Assembly of a Cross-Beta Amyloid Fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
4I0C
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THE STRUCTURE OF THE CAMELID ANTIBODY CABHUL5 IN COMPLEX WITH HUMAN LYSOZYME
分子名称:Lysozyme C, cAbHuL5 antibody, CHLORIDE ION, ...
著者De Genst, E., Chan, P.H., Pardon, E., Kumita, J.R., Christodoulou, J., Menzer, L., Chirgadze, D.Y., Robinson, C.V., Muyldermans, S., Matagne, A., Wyns, L., Dobson, C.M., Dumoulin, M.
登録日2012-11-16
公開日2013-10-09
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
J.Phys.Chem.B, 117, 2013
4RAV
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CRYSTAL STRUCTURE OF SCFVC4 IN COMPLEX WITH THE FIRST 17 AA OF HUNTINGTIN
分子名称:Single-chain Fv, VL, single-chain Fv, ...
著者De Genst, E., Chirgadze, D.Y., Dobson, C.M.
登録日2014-09-11
公開日2015-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a single-chain fv bound to the 17 N-terminal residues of huntingtin provides insights into pathogenic amyloid formation and suppression.
J.Mol.Biol., 427, 2015
1LOZ
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AMYLOIDOGENIC VARIANT (I56T) VARIANT OF HUMAN LYSOZYME
分子名称:LYSOZYME
著者Sunde, M., Blake, C.C.F.
登録日1997-01-16
公開日1997-04-01
最終更新日2014-02-12
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis.
Nature, 385, 1997
1LSY
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CRYSTAL STRUCTURE OF THE MUTANT D52S HEN EGG WHITE LYSOZYME WITH AN OLIGOSACCHARIDE PRODUCT
分子名称:HEN EGG WHITE LYSOZYME
著者Johnson, L.N., Hadfield, A.T.
登録日1994-09-27
公開日1995-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the mutant D52S hen egg white lysozyme with an oligosaccharide product.
J.Mol.Biol., 243, 1994
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