Author results

4ZDV
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CRYSTAL STRUCTURE OF LC3 IN COMPLEX WITH FAM134B LIR
Descriptor:Microtubule-associated proteins 1A/1B light chain 3A
Authors:Khaminets, A., Grumati, P., Dikic, I., Akutsu, M.
Deposit date:2015-04-19
Release date:2015-06-03
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Regulation of endoplasmic reticulum turnover by selective autophagy.
Nature, 522, 2015
5M93
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CRYSTAL STRUCTURE OF SDEA-MODIFIED UBIQUITIN.
Descriptor:Polyubiquitin-B, SULFATE ION, RIBOSE
Authors:Kalayil, S., Bhogaraju, S., Dikic, I.
Deposit date:2016-10-31
Release date:2016-12-14
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination.
Cell, 167, 2016
2AK5
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BETA PIX-SH3 COMPLEXED WITH A CBL-B PEPTIDE
Descriptor:Rho guanine nucleotide exchange factor 7, 8-residue peptide from a signal transduction protein CBL-B
Authors:Jozic, D., Cardenes, N., Deribe, Y.L., Moncalian, G., Hoeller, D., Groemping, Y., Dikic, I., Rittinger, K., Bravo, J.
Deposit date:2005-08-03
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Cbl promotes clustering of endocytic adaptor proteins.
Nat.Struct.Mol.Biol., 12, 2005
2J6F
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N-TERMINAL SH3 DOMAIN OF CMS (CD2AP HUMAN HOMOLOG) BOUND TO CBL-B PEPTIDE
Descriptor:CD2-ASSOCIATED PROTEIN, E3 UBIQUITIN-PROTEIN LIGASE CBL-B
Authors:Moncalian, G., Cardenes, N., Deribe, Y.L., Spinola-Amilibia, M., Dikic, I., Bravo, J.
Deposit date:2006-09-28
Release date:2006-10-11
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atypical Polyproline Recognition by the Cms N- Terminal SH3 Domain.
J.Biol.Chem., 281, 2006
2J6K
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N-TERMINAL SH3 DOMAIN OF CMS (CD2AP HUMAN HOMOLOG)
Descriptor:CD2-ASSOCIATED PROTEIN, SODIUM ION
Authors:Moncalian, G., Cardenes, N., Deribe, Y.L., Spinola-Amilibia, M., Dikic, I., Bravo, J.
Deposit date:2006-09-29
Release date:2006-10-11
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Atypical Polyproline Recognition by the Cms N- Terminal SH3 Domain.
J.Biol.Chem., 281, 2006
2J6O
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ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETEROTRIMER
Descriptor:CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2
Authors:Moncalian, G., Cardenes, N., Deribe, Y.L., Spinola-Amilibia, M., Dikic, I., Bravo, J.
Deposit date:2006-10-02
Release date:2006-10-11
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Atypical Polyproline Recognition by the Cms N-Terminal SH3 Domain.
J.Biol.Chem., 281, 2006
2J7I
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ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETERODIMER
Descriptor:CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2
Authors:Moncalian, G., Cardenes, N., Deribe, Y.L., Spinola-Amilibia, M., Dikic, I., Bravo, J.
Deposit date:2006-10-09
Release date:2006-11-06
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Atypical Polyproline Recognition by the Cms N-Terminal Src Homology 3 Domain.
J.Biol.Chem., 281, 2006
2KHU
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SOLUTION STRUCTURE OF THE UBIQUITIN-BINDING MOTIF OF HUMAN POLYMERASE IOTA
Descriptor:Immunoglobulin G-binding protein G, DNA polymerase iota
Authors:Bomar, M.G., D'Souza, S., Bienko, M., Dikic, I., Walker, G.
Deposit date:2009-04-11
Release date:2010-02-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Unconventional Ubiquitin Recognition by the Ubiquitin-Binding Motif within the Y Family DNA Polymerases iota and Rev1.
Mol.Cell, 37, 2010
2KHW
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SOLUTION STRUCTURE OF THE HUMAN POLYMERASE IOTA UBM2-UBIQUITIN COMPLEX
Descriptor:Immunoglobulin G-binding protein G, DNA polymerase iota, Ubiquitin
Authors:Bomar, M.G., D'Souza, S., Bienko, M., Dikic, I., Walker, G.
Deposit date:2009-04-13
Release date:2010-02-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the human Polymerase iota UBM2-Ubiquitin Complex
To be Published
2L8J
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GABARAPL-1 NBR1-LIR COMPLEX STRUCTURE
Descriptor:Gamma-aminobutyric acid receptor-associated protein-like 1, NBR1-LIR peptide
Authors:Rogov, V.V., Rozenknop, A., Rogova, N.Y., Loehr, F., Guentert, P., Dikic, I., Doetsch, V.
Deposit date:2011-01-17
Release date:2011-05-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Characterization of the Interaction of GABARAPL-1 with the LIR Motif of NBR1.
J.Mol.Biol., 410, 2011
2MD9
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SOLUTION STRUCTURE OF AN ACTIVE SITE MUTANT PEPITDYL CARRIER PROTEIN
Descriptor:Tyrocidine synthase 3
Authors:Tufar, P., Rahighi, S., Kraas, F.I., Kirchner, D.K., Loehr, F., Henrich, E., Koepke, J., Dikic, I., Guentert, P., Marahiel, M.A., Doetsch, V.
Deposit date:2013-09-06
Release date:2014-04-23
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification.
Chem.Biol., 21, 2014
2O2O
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SOLUTION STRUCTURE OF DOMAIN B FROM HUMAN CIN85 PROTEIN
Descriptor:SH3-domain kinase-binding protein 1
Authors:Ababou, A., Pfuhl, M., Dikic, I., Ladbury, J.E.
Deposit date:2006-11-30
Release date:2007-11-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Investigation of Domain B from Human Cin85 Protein: Structure, Dynamics and Proline-Rich Motif Binding
To be Published
2R2Y
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CRYSTAL STRUCTURE OF THE PROTEASOMAL RPN13 PRU-DOMAIN
Descriptor:Protein ADRM1
Authors:Groll, M., Walters, K., Dikic, I., Finley, D.
Deposit date:2007-08-28
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction.
Nature, 453, 2008
2ZVN
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NEMO COZI DOMAIN INCOMPLEX WITH DIUBIQUITIN IN P212121 SPACE GROUP
Descriptor:UBC protein, NF-kappa-B essential modulator
Authors:Rahighi, S., Ikeda, F., Kawasaki, M., Akutsu, M., Suzuki, N., Kato, R., Kensche, T., Uejima, T., Bloor, S., Komander, D., Randow, F., Wakatsuki, S., Dikic, I.
Deposit date:2008-11-12
Release date:2009-03-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
2ZVO
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NEMO COZI DOMAIN IN COMPLEX WITH DIUBIQUITIN IN C2 SPACE GROUP
Descriptor:UBC protein, NF-kappa-B essential modulator
Authors:Rahighi, S., Ikeda, F., Kawasaki, M., Akutsu, M., Suzuki, N., Kato, R., Kensche, T., Uejima, T., Bloor, S., Komander, D., Randow, F., Wakatsuki, S., Dikic, I.
Deposit date:2008-11-12
Release date:2009-03-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
3AXC
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CRYSTAL STRUCTURE OF LINEAR DIUBIQUITIN
Descriptor:Ubiquitin, GLYCEROL
Authors:Rohaim, A., Kawasaki, M., Kato, R., Dikic, I., Wakatsuki, S.
Deposit date:2011-04-01
Release date:2012-01-25
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structure of a compact conformation of linear diubiquitin
Acta Crystallogr.,Sect.D, 68, 2012
3F89
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NEMO COZI DOMAIN
Descriptor:NF-kappa-B essential modulator
Authors:Rahighi, S., Ikeda, F., Kawasaki, M., Akutsu, M., Suzuki, N., Kato, R., Kensche, T., Uejima, T., Bloor, S., Komander, D., Randow, F., Wakatsuki, S., Dikic, I.
Deposit date:2008-11-11
Release date:2009-03-24
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
3X0W
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CRYSTAL STRUCTURE OF PLEKHM1 LIR-FUSED HUMAN LC3B_2-119
Descriptor:Microtubule-associated proteins 1A/1B light chain 3B
Authors:Suzuki, H., McEwan, D.G., Popovic, D., Gubas, A., Terawaki, S., Stadel, D., Coxon, F., Stegmann, D.M., Bhogaraju, S., Maddi, K., Kirchhoff, A., Gatti, E., Helfrich, M.H., Behrends, C., Pierre, P., Dikic, I., Wakatsuki, S.
Deposit date:2014-10-22
Release date:2015-01-14
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins.
Mol.Cell, 2014
4EMO
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CRYSTAL STRUCTURE OF THE PH DOMAIN OF SHARPIN
Descriptor:Sharpin
Authors:Stieglitz, B., Haire, L.F., Dikic, I., Rittinger, K.
Deposit date:2012-04-12
Release date:2012-05-02
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold.
J.Biol.Chem., 287, 2012
4MRT
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STRUCTURE OF THE PHOSPHOPANTETHEINE TRANSFERASE SFP IN COMPLEX WITH COENZYME A AND A PEPTIDYL CARRIER PROTEIN
Descriptor:Tyrocidine synthase 3, 4'-phosphopantetheinyl transferase sfp, MAGNESIUM ION, ...
Authors:Tufar, P., Rahighi, S., Kraas, F.I., Kirchner, D.K., Loehr, F., Henrich, E., Koepke, J., Dikic, I., Guentert, P., Marahiel, M.A., Doetsch, V.
Deposit date:2013-09-17
Release date:2014-04-23
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification.
Chem.Biol., 21, 2014
4P09
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CRYSTAL STRUCTURE OF HOIP PUB DOMAIN
Descriptor:E3 ubiquitin-protein ligase RNF31
Authors:Akutsu, M., Schaeffer, V., Olma, M.H., Gomes, L.C., Kawasaki, M., Dikic, I.
Deposit date:2014-02-20
Release date:2014-05-07
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling.
Mol.Cell, 54, 2014
4P0A
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CRYSTAL STRUCTURE OF HOIP PUB DOMAIN IN COMPLEX WITH P97 PIM
Descriptor:E3 ubiquitin-protein ligase RNF31, Transitional endoplasmic reticulum ATPase
Authors:Akutsu, M., Schaeffer, V., Olma, M.H., Gomes, L.C., Kawasaki, M., Dikic, I.
Deposit date:2014-02-20
Release date:2014-05-07
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3001 Å)
Cite:Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling.
Mol.Cell, 54, 2014
4P0B
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CRYSTAL STRUCTURE OF HOIP PUB DOMAIN IN COMPLEX WITH OTULIN PIM
Descriptor:E3 ubiquitin-protein ligase RNF31, Ubiquitin thioesterase otulin
Authors:Akutsu, M., Schaeffer, V., Olma, M.H., Gomes, L.C., Kawasaki, M., Dikic, I.
Deposit date:2014-02-20
Release date:2014-05-07
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.7005 Å)
Cite:Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling.
Mol.Cell, 54, 2014
5JW7
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CRYSTAL STRUCTURE OF SOPA-TRIM56 COMPLEX
Descriptor:E3 ubiquitin-protein ligase SopA, E3 ubiquitin-protein ligase TRIM56, ZINC ION
Authors:Bhogaraju, S., Dikic, I.
Deposit date:2016-05-11
Release date:2017-02-15
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA.
Nat Commun, 8, 2017
6G0C
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CRYSTAL STRUCTURE OF SDEA CATALYTIC CORE
Descriptor:Ubiquitinating/deubiquitinating enzyme SdeA, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, 1,2-ETHANEDIOL
Authors:Kalayil, S., Bhogaraju, S., Basquin, J., Dikic, I.
Deposit date:2018-03-17
Release date:2018-05-30
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination.
Nature, 557, 2018
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