Author results

1KTJ
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X-RAY STRUCTURE OF DER P 2, THE MAJOR HOUSE DUST MITE ALLERGEN
Descriptor:ALLERGEN DER P 2
Authors:Derewenda, U., Li, J., Derewenda, Z., Dauter, Z., Mueller, G.A., Rule, G.S., Benjamin, D.C.
Deposit date:2002-01-16
Release date:2002-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The crystal structure of a major dust mite allergen Der p 2, and its biological implications.
J.Mol.Biol., 318, 2002
1MFW
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STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: SELENOMETHIONINE LABELED PROTEIN
Descriptor:DOUBLECORTIN-LIKE KINASE (N-TERMINAL DOMAIN), SULFATE ION
Authors:Kim, M.H., Cierpickil, T., Derewenda, U., Krowarsch, D., Feng, Y., Devedjiev, Y., Dauter, Z., Walsh, C.A., Otlewski, J., Bushweller, J.H., Derewenda, Z.
Deposit date:2002-08-13
Release date:2003-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
1MG4
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STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: WILD TYPE PROTEIN
Descriptor:DOUBLECORTIN-LIKE KINASE (N-TERMINAL DOMAIN), SULFATE ION
Authors:Kim, M.H., Cierpickil, T., Derewenda, U., Krowarsch, D., Feng, Y., Devedjiev, Y., Dauter, Z., Walsh, C.A., Otlewski, J., Bushweller, J.H., Derewenda, Z.
Deposit date:2002-08-14
Release date:2003-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.504 Å)
Cite:The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
6INS
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X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE
Descriptor:INSULIN, ZINC ION
Authors:Derewenda, U., Derewenda, Z., Dodson, E.J., Dodson, G.G., Bing, X., Markussen, J.
Deposit date:1992-11-25
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.
J.Mol.Biol., 220, 1991
1HGA
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HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN
Descriptor:HEMOGLOBIN (DEOXY) (ALPHA CHAIN), HEMOGLOBIN (DEOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE
Authors:Liddington, R., Derewenda, Z., Dodson, E., Hubbard, R., Dodson, G.
Deposit date:1991-10-31
Release date:1994-01-31
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High resolution crystal structures and comparisons of T-state deoxyhaemoglobin and two liganded T-state haemoglobins: T(alpha-oxy)haemoglobin and T(met)haemoglobin.
J.Mol.Biol., 228, 1992
1HGB
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HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN
Descriptor:HEMOGLOBIN (AQUO MET) (ALPHA CHAIN), HEMOGLOBIN (AQUO MET) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE
Authors:Liddington, R., Derewenda, Z., Dodson, E., Hubbard, R., Dodson, G.
Deposit date:1991-10-31
Release date:1994-01-31
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High resolution crystal structures and comparisons of T-state deoxyhaemoglobin and two liganded T-state haemoglobins: T(alpha-oxy)haemoglobin and T(met)haemoglobin.
J.Mol.Biol., 228, 1992
1HGC
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HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN
Descriptor:HEMOGLOBIN (OXY) (ALPHA CHAIN), HEMOGLOBIN (DEOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Liddington, R., Derewenda, Z., Dodson, E., Hubbard, R., Dodson, G.
Deposit date:1991-10-31
Release date:1994-01-31
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High resolution crystal structures and comparisons of T-state deoxyhaemoglobin and two liganded T-state haemoglobins: T(alpha-oxy)haemoglobin and T(met)haemoglobin.
J.Mol.Biol., 228, 1992
2AAA
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CALCIUM BINDING IN ALPHA-AMYLASES: AN X-RAY DIFFRACTION STUDY AT 2.1 ANGSTROMS RESOLUTION OF TWO ENZYMES FROM ASPERGILLUS
Descriptor:ALPHA-AMYLASE, CALCIUM ION
Authors:Brady, L., Brzozowski, A.M., Derewenda, Z., Dodson, E.J., Dodson, G.G.
Deposit date:1991-02-27
Release date:1993-07-15
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Calcium binding in alpha-amylases: an X-ray diffraction study at 2.1-A resolution of two enzymes from Aspergillus.
Biochemistry, 29, 1990
1FXW
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CRYSTAL STRUCTURE OF THE RECOMBINANT ALPHA1/ALPHA2 CATALYTIC HETERODIMER OF BOVINE BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB.
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB BETA SUBUNIT, CALCIUM ION
Authors:Derewenda, Z., Li, J.
Deposit date:2000-09-27
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Preparation and crystal structure of the recombinant alpha(1)/alpha(2) catalytic heterodimer of bovine brain platelet-activating factor acetylhydrolase Ib.
Protein Eng., 14, 2001
1BWP
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S., Sheffield, P.J., Masuyama, J., Arai, H., Li, J., Aoki, J., Inoue, K., Derewenda, U., Derewenda, Z.
Deposit date:1998-09-27
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1BWQ
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S., Sheffield, P.J., Masuyama, J., Arai, H., Li, J., Aoki, J., Inoue, K., Derewenda, U., Derewenda, Z.
Deposit date:1998-09-27
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1BWR
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S., Sheffield, P.J., Masuyama, J., Arai, H., Li, J., Aoki, J., Inoue, K., Derewenda, U., Derewenda, Z.
Deposit date:1998-09-27
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
3QOR
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CRYSTAL STRUCTURE OF HUMAN NUCLEAR MIGRATION PROTEIN NUDC
Descriptor:Nuclear migration protein nudC, ACETATE ION
Authors:Derewenda, U., Derewenda, Z., Zheng, M.
Deposit date:2011-02-10
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.753 Å)
Cite:Structural Features and Chaperone Activity of the NudC Protein Family.
J.Mol.Biol., 409, 2011
1FJ2
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CRYSTAL STRUCTURE OF THE HUMAN ACYL PROTEIN THIOESTERASE 1 AT 1.5 A RESOLUTION
Descriptor:PROTEIN (ACYL PROTEIN THIOESTERASE 1), BROMIDE ION
Authors:Devedjiev, Y., Dauter, Z., Kuznetsov, S., Jones, T., Derewenda, Z.
Deposit date:2000-08-07
Release date:2000-11-29
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A.
Structure Fold.Des., 8, 2000
1ZNI
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INSULIN
Descriptor:INSULIN, ZINC ION, CHLORIDE ION
Authors:Turkenburg, M.G.W., Whittingham, J.L., Dodson, G.G., Dodson, E.J., Xiao, B., Bentley, G.A.
Deposit date:1997-09-23
Release date:1998-01-28
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.498 Å)
Cite:Structure of insulin in 4-zinc insulin.
Nature, 261, 1976
1YBO
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CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN WITH SYNDECAN PEPTIDE
Descriptor:Syntenin 1, Syndecan-4
Authors:Grembecka, J., Cooper, D.R., Cierpicki, T., Kang, B.S., Devedjiev, Y., Derewenda, Z.
Deposit date:2004-12-21
Release date:2006-01-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The binding of the PDZ tandem of syntenin to target proteins
Biochemistry, 45, 2006
5IRC
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P190A GAP DOMAIN COMPLEX WITH RHOA
Descriptor:Rho GTPase-activating protein 35, Transforming protein RhoA, CHLORIDE ION, ...
Authors:Derewenda, U., Derewenda, Z.
Deposit date:2016-03-12
Release date:2016-08-17
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
J.Biol.Chem., 291, 2016
1ZNJ
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INSULIN, MONOCLINIC CRYSTAL FORM
Descriptor:INSULIN, PHENOL, ZINC ION, ...
Authors:Turkenburg, M.G.W., Whittingham, J.L., Turkenburg, J.P., Dodson, G.G., Derewenda, U., Smith, G.D., Dodson, E.J., Derewenda, Z.S., Xiao, B.
Deposit date:1997-09-23
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure Determination and Refinement of Two Crystal Forms of Native Insulins
To be Published
6TAA
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STRUCTURE AND MOLECULAR MODEL REFINEMENT OF ASPERGILLUS ORYZAE (TAKA) ALPHA-AMYLASE: AN APPLICATION OF THE SIMULATED-ANNEALING METHOD
Descriptor:ALPHA-AMYLASE, CALCIUM ION
Authors:Swift, H.J., Brady, L., Derewenda, Z.S., Dodson, E.J., Turkenburg, J.P., Wilkinson, A.J.
Deposit date:1992-08-21
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method.
Acta Crystallogr.,Sect.B, 47, 1991
7INS
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STRUCTURE OF PORCINE INSULIN COCRYSTALLIZED WITH CLUPEINE Z
Descriptor:INSULIN (CHAIN A), INSULIN (CHAIN B), GENERAL PROTAMINE CHAIN, ...
Authors:Balschmidt, P., Hansen, F.B., Dodson, E., Dodson, G., Korber, F.
Deposit date:1991-09-03
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of porcine insulin cocrystallized with clupeine Z.
Acta Crystallogr.,Sect.B, 47, 1991
1AH7
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PHOSPHOLIPASE C FROM BACILLUS CEREUS
Descriptor:PHOSPHOLIPASE C, ZINC ION
Authors:Greaves, R.
Deposit date:1997-04-14
Release date:1997-12-10
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:High-resolution (1.5 A) crystal structure of phospholipase C from Bacillus cereus.
Nature, 338, 1989
1IZA
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ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN
Descriptor:INSULIN
Authors:Xiao, B., Dodson, G.G.
Deposit date:1992-10-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin.
J.Mol.Biol., 228, 1992
1IZB
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ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN
Descriptor:INSULIN, ZINC ION
Authors:Xiao, B., Dodson, G.G.
Deposit date:1992-10-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin.
J.Mol.Biol., 228, 1992
3V19
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FORESTALLING INSULIN FIBRILLATION BY INSERTION OF A CHIRAL CLAMP MECHANISM-BASED APPLICATION OF PROTEIN ENGINEERING TO GLOBAL HEALTH
Descriptor:Insulin, ZINC ION, CHLORIDE ION, ...
Authors:Wan, Z.L., Hua, Q.X., Wickramasinghe, N.P., Huang, K., Petkova, A.T., Hu, S.Q., Phillips, N.B., Yeh, I.J., Whittake, J., Ismail-Beigi, F., Katsoyyannis, P.G., Tycko, R., Weiss, M.A.
Deposit date:2011-12-09
Release date:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
To be Published
3V1G
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FORESTALLING INSULIN FIBRILLATION BY INSERTION OF A CHIRAL CLAMP MECHANISM-BASED APPLICATION OF PROTEIN ENGINEERING TO GLOBAL HEALTH
Descriptor:Insulin, ZINC ION, PHENOL, ...
Authors:Wan, Z.L., Hua, Q.X., Wickramasinghe, N.P., Huang, K., Petkova, A.T., Hu, S.Q., Phillips, N.B., Yeh, I.J., Whittake, J., Ismail-Beigi, F., Katsoyyannis, P.G., Tycko, R., Weiss, M.A.
Deposit date:2011-12-09
Release date:2012-12-12
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
To be Published
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