Author results

2B4V
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STRUCTURAL BASIS FOR UTP SPECIFICITY OF RNA EDITING TUTASES FROM TRYPANOSOMA BRUCEI
Descriptor:RNA editing complex protein MP57, POTASSIUM ION
Authors:Deng, J., Ernst, N.L., Turley, S., Stuart, K.D., Hol, W.G.
Deposit date:2005-09-26
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
2B51
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STRUCTURAL BASIS FOR UTP SPECIFICITY OF RNA EDITING TUTASES FROM TRYPANOSOMA BRUCEI
Descriptor:RNA editing complex protein MP57, MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE
Authors:Deng, J., Ernst, N.L., Turley, S., Stuart, K.D., Hol, W.G.
Deposit date:2005-09-27
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
2B56
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STRUCTURAL BASIS FOR UTP SPECIFICITY OF RNA EDITING TUTASES FROM TRYPANOSOMA BRUCEI
Descriptor:RNA editing complex protein MP57, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE, ...
Authors:Deng, J., Ernst, N.L., Turley, S., Stuart, K.D., Hol, W.G.
Deposit date:2005-09-27
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
1FUF
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CRYSTAL STRUCTURE OF A 14BP RNA OLIGONUCLEOTIDE CONTAINING DOUBLE UU BULGES: A NOVEL INTRAMOLECULAR U*(AU) BASE TRIPLE
Descriptor:(5'-R(*GP*GP*UP*AP*UP*UP*UP*CP*GP*GP*UP*AP*(CBR)P*C)-3'), MAGNESIUM ION, SPERMINE
Authors:Deng, J., Xiong, Y., Sudarsanakumar, C., Shi, K., Sundaralingam, M.
Deposit date:2000-09-15
Release date:2001-11-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of two forms of a 14-mer RNA/DNA chimer duplex with double UU bulges: a novel intramolecular U*(A x U) base triple.
RNA, 7, 2001
1IK5
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CRYSTAL STRUCTURE OF A 14MER RNA CONTAINING DOUBLE UU BULGES IN TWO CRYSTAL FORMS: A NOVEL U*(AU) INTRAMOLECULAR BASE TRIPLE
Descriptor:5'-R(*GP*GP*UP*AP*UP*UP*UP*CP*GP*GP*UP*AP*(CBR)P*C)-3', 5'-R(*GP*GP*UP*AP*UP*UP*UP*UP*GP*GP*UP*AP*(CBR)P*C)-3', MAGNESIUM ION
Authors:Deng, J., Xiong, Y., Sudarsanakumar, C., Shi, K., Sundaralingam, M.
Deposit date:2001-05-02
Release date:2001-11-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of two forms of a 14-mer RNA/DNA chimer duplex with double UU bulges: a novel intramolecular U*(A x U) base triple.
RNA, 7, 2001
1J8G
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X-RAY ANALYSIS OF A RNA TETRAPLEX R(UGGGGU)4 AT ULTRA-HIGH RESOLUTION
Descriptor:5'-R(*UP*GP*GP*GP*GP*U)-3', SPERMINE, STRONTIUM ION, ...
Authors:Deng, J., Xiong, Y., Sundaralingam, M.
Deposit date:2001-05-21
Release date:2001-11-23
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (0.61 Å)
Cite:X-ray analysis of an RNA tetraplex (UGGGGU)(4) with divalent Sr(2+) ions at subatomic resolution (0.61 A).
Proc.Natl.Acad.Sci.USA, 98, 2001
1JUX
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1.6A RESOLUTION CRYSTAL STRUCTURES OF THE DNA OCTAMERS D(IUATATAC) AND D(ITITACAC):BINDING OF TWO DISTAMYCIN DRUGS SIDE-BY-SIDE
Descriptor:5'-D(*IP*TP*IP*TP*AP*CP*AP*C)-3', DISTAMYCIN A
Authors:Deng, J., Pan, B., Sundaralingam, M.
Deposit date:2001-08-28
Release date:2004-01-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of d(ITITACAC) complexed with distamycin at 1.6 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
1LNT
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CRYSTAL STRUCTURE OF THE HIGHLY CONSERVED RNA INTERNAL LOOP OF SRP
Descriptor:5'-R(*GP*CP*GP*UP*CP*AP*GP*GP*UP*CP*(CBV)P*G)-3', 5'-R(*CP*GP*GP*AP*AP*GP*CP*AP*GP*(CBV)P*GP*C)-3', MAGNESIUM ION, ...
Authors:Deng, J., Xiong, Y., Pan, B., Sundaralingam, M.
Deposit date:2002-05-03
Release date:2003-06-03
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of an RNA dodecamer containing a fragment from SRP domain IV of Escherichia coli.
Acta Crystallogr.,Sect.D, 59, 2003
1XDN
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HIGH RESOLUTION CRYSTAL STRUCTURE OF AN EDITOSOME ENZYME FROM TRYPANOSOMA BRUCEI: RNA EDITING LIGASE 1
Descriptor:RNA editing ligase MP52, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Deng, J., Schnaufer, A., Salavati, R., Stuart, K.D., Hol, W.G.
Deposit date:2004-09-07
Release date:2004-12-07
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:High resolution crystal structure of a key editosome enzyme from Trypanosoma brucei: RNA editing ligase 1.
J.Mol.Biol., 343, 2004
2ZEJ
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STRUCTURE OF THE ROC DOMAIN FROM THE PARKINSON'S DISEASE-ASSOCIATED LEUCINE-RICH REPEAT KINASE 2 REVEALS A DIMERIC GTPASE
Descriptor:Leucine-rich repeat kinase 2, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Deng, J.
Deposit date:2007-12-13
Release date:2008-01-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
Proc.Natl.Acad.Sci.Usa, 105, 2008
3D6T
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STRUCTURE OF THE ROC DOMAIN FROM THE PARKINSON'S DISEASE-ASSOCIATED LEUCINE-RICH REPEAT KINASE 2 REVEALS A DIMERIC GTPASE
Descriptor:Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Deng, J.
Deposit date:2008-05-20
Release date:2008-06-10
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
Proc.Natl.Acad.Sci.Usa, 105, 2008
472D
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STRUCTURE OF AN OCTAMER RNA WITH TANDEM GG/UU MISPAIRS
Descriptor:RNA (5'-R(*GP*UP*GP*UP*UP*UP*AP*C)-3'), RNA (5'-R(*GP*UP*AP*GP*GP*CP*AP*C)-3')
Authors:Deng, J., Sundaralingam, M.
Deposit date:1999-05-14
Release date:2000-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis and crystal structure of an octamer RNA r(guguuuac)/r(guaggcac) with G.G/U.U tandem wobble base pairs: comparison with other tandem G.U pairs.
Nucleic Acids Res., 28, 2000
5UC4
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HSP90B N-TERMINAL DOMAIN WITH INHIBITORS
Descriptor:Heat shock protein HSP 90-beta, 5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylbenzaldehyde, GLYCEROL, ...
Authors:Deng, J., Peng, S., Balch, M., Matts, R.
Deposit date:2016-12-21
Release date:2018-01-17
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor.
Nat Commun, 9, 2018
6BR8
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STRUCTURE OF A6 REVEALS A NOVEL LIPID TRANSPORTER
Descriptor:Protein A6 homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE
Authors:Deng, J., Peng, S., Pathak, P.
Deposit date:2017-11-30
Release date:2018-06-20
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BR9
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STRUCTURE OF A6 REVEALS A NOVEL LIPID TRANSPORTER
Descriptor:Protein A6 homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE
Authors:Deng, J., Peng, S., Pathak, P.
Deposit date:2017-11-30
Release date:2018-06-20
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1J6S
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CRYSTAL STRUCTURE OF AN RNA TETRAPLEX (UGAGGU)4 WITH A-TETRADS, G-TETRADS, U-TETRADS AND G-U OCTADS
Descriptor:5'-R(*(BRUP*GP*AP*GP*GP*U)-3', BARIUM ION, SODIUM ION
Authors:Pan, B., Xiong, Y., Shi, K., Deng, J., Sundaralingam, M.
Deposit date:2002-07-10
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of an RNA purine-rich tetraplex containing adenine tetrads: implications for specific binding in RNA tetraplexes
Structure, 11, 2003
1J9H
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CRYSTAL STRUCTURE OF AN RNA DUPLEX WITH URIDINE BULGES
Descriptor:5'-R(*GP*UP*GP*UP*CP*GP*(CBR)P*AP*C)-3', CALCIUM ION
Authors:Xiong, Y., Deng, J., Sudarsanakumar, C., Sundaralingam, M.
Deposit date:2001-05-25
Release date:2001-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of an RNA duplex r(gugucgcac)(2) with uridine bulges.
J.Mol.Biol., 313, 2001
1JZV
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CRYSTAL STRUCTURE OF A BULGED RNA FROM THE SL2 STEM-LOOP OF THE HIV-1 PSI-RNA
Descriptor:5'-R(*GP*GP*CP*GP*AP*CP*(5BU)P*G)-3', 5'-R(*CP*AP*GP*UP*AP*CP*GP*(5IC)P*C)-3', MAGNESIUM ION
Authors:Xiong, Y., Sudarsanakumar, C., Deng, J., Pan, B., Sundaralingam, M.
Deposit date:2001-09-17
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of a Bulged RNA from the SL2 Stem-loop of the HIV-1 psi-RNA
To be Published
3F62
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CRYSTAL STRUCTURE OF HUMAN IL-18 IN COMPLEX WITH ECTROMELIA VIRUS IL-18 BINDING PROTEIN
Descriptor:Interleukin 18 binding protein, Interleukin-18
Authors:Krumm, B.E., Li, Y., Deng, J.
Deposit date:2008-11-05
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein.
Proc.Natl.Acad.Sci.USA, 105, 2008
3HHS
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CRYSTAL STRUCTURE OF MANDUCA SEXTA PROPHENOLOXIDASE
Descriptor:Phenoloxidase subunit 2, Phenoloxidase subunit 1, COPPER (II) ION
Authors:Li, Y., Wang, Y., Jiang, H., Deng, J.
Deposit date:2009-05-17
Release date:2009-09-29
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of Manduca sexta prophenoloxidase provides insights into the mechanism of type 3 copper enzymes.
Proc.Natl.Acad.Sci.USA, 106, 2009
3VBC
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CRYSTAL STRUCTURE OF IL-17 RECEPTOR B SEFIR DOMAIN
Descriptor:Interleukin-17 receptor B
Authors:Zhang, B., Liu, C., Li, X., Deng, J.
Deposit date:2012-01-02
Release date:2013-02-06
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of IL-17 Receptor B SEFIR Domain.
J.Immunol., 190, 2013
4EEE
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CRYSTAL STRUCTURE OF YLDV 14L IL-18 BINDING PROTEIN IN COMPLEX WITH HUMAN IL-18
Descriptor:14L protein, Interleukin-18
Authors:Krumm, B.E., Xiang, Y., Deng, J.
Deposit date:2012-03-28
Release date:2012-09-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein.
Plos Pathog., 8, 2012
4EKX
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CRYSTAL STRUCTURE OF YLDV 14L IL-18 BINDING PROTEIN IN COMPLEX WITH HUMAN IL-18
Descriptor:14L protein, Interleukin-18
Authors:Krumm, B.E., Xiang, Y., Deng, J.
Deposit date:2012-04-10
Release date:2012-09-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein.
Plos Pathog., 8, 2012
4NUX
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STRUCTURE OF RECEPTOR A
Descriptor:Interleukin-17 receptor A
Authors:Zhang, B., Han, Y., Deng, J.
Deposit date:2013-12-04
Release date:2014-05-14
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved alpha-helix for Act1 binding and IL-17 signaling.
Acta Crystallogr.,Sect.D, 70, 2014
4W5X
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THE STRUCTURE OF VACCINA VIRUS H7 PROTEIN DISPLAYS A NOVEL PHOSPHOINOSITIDE BINDING FOLD REQUIRED FOR MEMBRANE BIOGENESIS
Descriptor:Late protein H7
Authors:Kolli, S., Deng, J.
Deposit date:2014-08-19
Release date:2014-12-31
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Structure-function analysis of vaccinia virus h7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication.
J.Virol., 89, 2015
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