Author results

4AQH
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PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH THE INHIBITOR AZ3976
Descriptor:PLASMINOGEN ACTIVATOR INHIBITOR 1, TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE
Authors:Fjellstrom, O., Deinum, J., Sjogren, T., Johansson, C., Geschwindner, S., Nerme, V., Legnehed, A., McPheat, J., Olsson, K., Bodin, C., Gustafsson, D.
Deposit date:2012-04-17
Release date:2012-11-28
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 that Accelerates the Transition Into the Latent Conformation
J.Biol.Chem., 288, 2013
1A7C
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HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE
Descriptor:PLASMINOGEN ACTIVATOR INHIBITOR TYPE 1, PENTAPEPTIDE, RIBOSE(PYRANOSE FORM), ...
Authors:Xue, Y., Inghardt, T., Sjolin, L., Deinum, J.
Deposit date:1998-03-12
Release date:1999-03-23
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide
Structure, 6, 1998
2V00
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X-RAY CRYSTAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH COMPOUND 1
Descriptor:ENDOTHIAPEPSIN, GLYCEROL, ACETATE ION, ...
Authors:Geschwindner, S., Olsson, L.L., Deinum, J., Albert, J.S., Edwards, P.D., De Beer, T., Folmer, R.H.A.
Deposit date:2007-05-03
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery of a Novel Warhead Against Beta-Secretase Through Fragment-Based Lead Generation.
J.Med.Chem., 50, 2007
4BAH
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THROMBIN IN COMPLEX WITH INHIBITOR
Descriptor:THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN VARIANT-1, ...
Authors:Xue, Y., Musil, D.
Deposit date:2012-09-14
Release date:2013-01-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors.
Biochemistry, 52, 2013
4BAK
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THROMBIN IN COMPLEX WITH INHIBITOR
Descriptor:THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN VARIANT-1, ...
Authors:Xue, Y., Musil, D.
Deposit date:2012-09-14
Release date:2013-01-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors.
Biochemistry, 52, 2013
4BAM
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THROMBIN IN COMPLEX WITH INHIBITOR
Descriptor:THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN VARIANT-1, ...
Authors:Xue, Y., Musil, D.
Deposit date:2012-09-14
Release date:2013-01-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors.
Biochemistry, 52, 2013
4BAN
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THROMBIN IN COMPLEX WITH INHIBITOR
Descriptor:THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN VARIANT-2, ...
Authors:Xue, Y., Musil, D.
Deposit date:2012-09-14
Release date:2013-01-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors.
Biochemistry, 52, 2013
4BAO
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THROMBIN IN COMPLEX WITH INHIBITOR
Descriptor:THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN VARIANT-2, ...
Authors:Xue, Y., Musil, D.
Deposit date:2012-09-14
Release date:2013-01-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors.
Biochemistry, 52, 2013
4BAQ
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THROMBIN IN COMPLEX WITH INHIBITOR
Descriptor:THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN VARIANT-1, ...
Authors:Xue, Y., Musil, D.
Deposit date:2012-09-14
Release date:2013-01-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors.
Biochemistry, 52, 2013
3BG8
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CRYSTAL STRUCTURE OF FACTOR XIA IN COMPLEX WITH CLAVATADINE A
Descriptor:Coagulation factor XIa light chain, N-(R-CARBOXY-ETHYL)-ALPHA-(S)-(2-PHENYLETHYL)GLYCYL-L-ARGININE-N-PHENYLAMIDE, BENZAMIDINE, ...
Authors:Xue, Y., Oster, L.
Deposit date:2007-11-26
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa.
J.Med.Chem., 51, 2008