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6EHT
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MODULATION OF PCNA SLIDING SURFACE BY P15PAF SUGGESTS A SUPPRESSIVE MECHANISM FOR CISPLATIN-INDUCED DNA LESION BYPASS BY POL ETA HOLOENZYME
Descriptor:Proliferating cell nuclear antigen, PCNA-associated factor, DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), ...
Authors:De March, M., Barrera-Vilarmau, S., Mentegari, E., Merino, N., Bressan, E., Maga, G., Crehuet, R., Onesti, S., Blanco, F.J., De Biasio, A.
Deposit date:2017-09-15
Release date:2018-08-08
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
6GIS
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STRUCTURAL BASIS OF HUMAN CLAMP SLIDING ON DNA
Descriptor:Proliferating cell nuclear antigen, DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3')
Authors:De March, M., Merino, N., Barrera-Vilarmau, S., Crehuet, R., Onesti, S., Blanco, F.J., De Biasio, A.
Deposit date:2018-05-15
Release date:2018-05-30
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
6GWS
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CRYSTAL STRUCTURE OF HUMAN PCNA IN COMPLEX WITH THREE P15 PEPTIDES
Descriptor:Proliferating cell nuclear antigen, PCNA-associated factor
Authors:De March, M., Merino, N., Gonzalez-Magana, A., Romano-Moreno, M., Onesti, S., Blanco, F.J., De Biasio, A.
Deposit date:2018-06-25
Release date:2018-08-22
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
6HVO
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CRYSTAL STRUCTURE OF HUMAN PCNA IN COMPLEX WITH THREE PEPTIDES OF P12 SUBUNIT OF HUMAN POLYMERASE DELTA
Descriptor:Proliferating cell nuclear antigen, DNA polymerase delta subunit 4, SULFATE ION
Authors:Gonzalez-Magana, A., Romano-Moreno, M., Rojas, A.L., Blanco, F.J., De Biasio, A.
Deposit date:2018-10-11
Release date:2019-01-23
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The p12 subunit of human polymerase delta uses an atypical PIP-box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J. Biol. Chem., 2019
3OP8
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CRYSTAL STRUCTURE OF THE DOMAIN V FROM BETA2-GLYCOPROTEIN I
Descriptor:Beta-2-glycoprotein 1, SULFATE ION
Authors:Kolyada, A., Lee, C.-J., De Biasio, A., Beglova, N.
Deposit date:2010-08-31
Release date:2011-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Novel Dimeric Inhibitor Targeting Beta2GPI in Beta2GPI/Antibody Complexes Implicated in Antiphospholipid Syndrome.
Plos One, 5, 2010
4D2G
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CRYSTAL STRUCTURE OF HUMAN PCNA IN COMPLEX WITH P15 PEPTIDE
Descriptor:PROLIFERATING CELL NUCLEAR ANTIGEN, P15
Authors:DeBiasio, A., Ibanez, A., Mortuza, G., Molina, R., Cordeiro, T.N., Castillo, F., Villate, M., Merino, N., Lelli, M., Diercks, T., Luque, I., Bernardo, P., Montoya, G., Blanco, F.J.
Deposit date:2014-05-09
Release date:2015-03-18
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
2KRI
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STRUCTURE OF A COMPLEX BETWEEN DOMAIN V OF BETA2-GLYCOPROTEIN I AND THE FOURTH LIGAND-BINDING MODULE FROM LDLR DETERMINED WITH HADDOCK
Descriptor:Beta-2-glycoprotein 1, Low-density lipoprotein receptor, CALCIUM ION
Authors:Beglova, N.
Deposit date:2009-12-18
Release date:2010-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Mode of interaction between beta2GPI and lipoprotein receptors suggests mutually exclusive binding of beta2GPI to the receptors and anionic phospholipids.
Structure, 18, 2010
4ZTD
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CRYSTAL STRUCTURE OF HUMAN PCNA IN COMPLEX WITH A TRAIP PEPTIDE
Descriptor:Proliferating cell nuclear antigen, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, ALA-GLY-ALA-GLY-ALA
Authors:Montoya, G., Mortuza, G.B., Blanco, F.J., Ibanez de Opakua, A.
Deposit date:2015-05-14
Release date:2015-12-16
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016