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7NS6
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BU of 7ns6 by Molmil
SARS-CoV-2 Spike (dimers) in complex with six Fu2 nanobodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fu2 nanobody, Spike glycoprotein,Fibritin, ...
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-03-05
Release date:2022-02-02
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Nat Commun, 13, 2022
7PZP
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BU of 7pzp by Molmil
Mitochondrial DNA dependent RNA polymerase homodimer.
Descriptor: DNA-directed RNA polymerase, mitochondrial
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-10-13
Release date:2022-09-28
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
7PZR
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BU of 7pzr by Molmil
Cryo-EM structure of POLRMT in free form.
Descriptor: DNA-directed RNA polymerase, mitochondrial
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-10-13
Release date:2022-11-16
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
7NLL
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BU of 7nll by Molmil
SARS-CoV-2 Spike RBD (dimer) in complex with two Fu2 nanobodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Fu2, Spike protein S1
Authors:Das, H, Hallberg, B.M.
Deposit date:2021-02-22
Release date:2022-02-02
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Nat Commun, 13, 2022
7ZC4
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BU of 7zc4 by Molmil
Cryo-EM structure of POLRMT mutant.
Descriptor: DNA-directed RNA polymerase, mitochondrial
Authors:Das, H, Hallberg, B.M.
Deposit date:2022-03-25
Release date:2023-02-01
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
7A25
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BU of 7a25 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2020-08-16
Release date:2020-11-25
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.
Nat Commun, 11, 2020
7KSG
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BU of 7ksg by Molmil
SARS-CoV-2 spike in complex with nanobodies E
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 glycoprotein, Spike glycoprotein
Authors:Hallberg, B.M, Das, H.
Deposit date:2020-11-22
Release date:2021-01-20
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021
7A29
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BU of 7a29 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neutralising sybody (Sb23), ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2020-08-16
Release date:2020-10-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.
Nat Commun, 11, 2020
6ZXN
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BU of 6zxn by Molmil
Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing nanobodies (Ty1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Ty1, ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2020-07-30
Release date:2020-09-23
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.
Nat Commun, 11, 2020
7B18
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BU of 7b18 by Molmil
SARS-CoV-spike bound to two neutralising nanobodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 VHH E, ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2020-11-24
Release date:2021-04-28
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021
8A99
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BU of 8a99 by Molmil
SARS Cov2 Spike in 1-up conformation complex with Fab47
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2022-06-28
Release date:2023-05-10
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
8A94
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BU of 8a94 by Molmil
SARS CoV2 Spike in the 2-up state in complex with Fab47.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain Variable domain), ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2022-06-27
Release date:2023-05-03
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
8A95
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BU of 8a95 by Molmil
SARS Cov2 Spike RBD in complex with Fab47
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2022-06-27
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
7B17
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BU of 7b17 by Molmil
SARS-CoV-spike RBD bound to two neutralising nanobodies.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama,SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama, Spike protein S1
Authors:Hallberg, B.M, Das, H.
Deposit date:2020-11-23
Release date:2021-02-10
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (4.01 Å)
Cite:Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
Science, 371, 2021
7B14
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BU of 7b14 by Molmil
Nanobody E bound to Spike-RBD in a localized reconstruction
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2, Spike protein S1
Authors:Hallberg, B.M, Das, H.
Deposit date:2020-11-23
Release date:2021-04-28
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
Science, 371, 2021
8A96
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BU of 8a96 by Molmil
SARS Cov2 Spike RBD in complex with Fab47
Descriptor: Fab47 Heavy chain (variable domain), Fab47 Light chain (variable domain), Spike protein S1
Authors:Hallberg, B.M, Das, H.
Deposit date:2022-06-27
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
7KN5
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BU of 7kn5 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobodies VHH E and U
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
Deposit date:2020-11-04
Release date:2021-01-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021
7KN6
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BU of 7kn6 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH V and antibody Fab CC12.3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ...
Authors:Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
Deposit date:2020-11-04
Release date:2021-01-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021
7KN7
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BU of 7kn7 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH W and antibody Fab CC12.3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ...
Authors:Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
Deposit date:2020-11-04
Release date:2021-01-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021

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