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3DQX
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BU of 3dqx by Molmil
chicken c-Src kinase domain in complex with ATPgS
Descriptor: ADENOSINE MONOPHOSPHATE, Proto-oncogene tyrosine-protein kinase Src
Authors:Azam, M, Seeliger, M.A, Gray, N, Kuriyan, J, Daley, G.Q.
Deposit date:2008-07-09
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Activation of tyrosine kinases by mutation of the gatekeeper threonine.
Nat.Struct.Mol.Biol., 15, 2008
3DQW
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BU of 3dqw by Molmil
c-Src kinase domain Thr338Ile mutant in complex with ATPgS
Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Proto-oncogene tyrosine-protein kinase Src
Authors:Azam, M, Seeliger, M.A, Gray, N, Kuriyan, J, Daley, G.Q.
Deposit date:2008-07-09
Release date:2008-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.017 Å)
Cite:Activation of tyrosine kinases by mutation of the gatekeeper threonine.
Nat.Struct.Mol.Biol., 15, 2008
3K5V
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BU of 3k5v by Molmil
Structure of Abl kinase in complex with imatinib and GNF-2
Descriptor: 3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, ...
Authors:Cowan-Jacob, S.W, Fendrich, G, Rummel, G, Strauss, A.
Deposit date:2009-10-08
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature, 463, 2010
3CS9
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BU of 3cs9 by Molmil
Human ABL kinase in complex with nilotinib
Descriptor: Nilotinib, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Cowan-Jacob, S.W, Fendrich, G, Manley, P, Liebetanz, J, Fabbro, D.
Deposit date:2008-04-09
Release date:2008-04-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
Cancer Cell, 7, 2005

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