Author results

1RK4
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CRYSTAL STRUCTURE OF A SOLUBLE DIMERIC FORM OF OXIDISED CLIC1
Descriptor:CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1
Authors:Littler, D.R., Harrop, S.J., Fairlie, W.D., Brown, L.J., Pankhurst, G.J., Pankhurst, S., DeMaere, M.Z., Campbell, T.J., Bauskin, A.R., Tonini, R., Mazzanti, M., Breit, S.N., Curmi, P.M.
Deposit date:2003-11-20
Release date:2003-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:The Intracellular Chloride Ion Channel Protein CLIC1 Undergoes a Redox-controlled Structural Transition
J.Biol.Chem., 279, 2004
2ARQ
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HUMAN PLASMINOGEN ACTIVATOR INHIBITOR-2.[LOOP (66-98) DELETION MUTANT] COMPLEXED WITH PEPTIDE N-ACETYL-TEAAAGDGGVMTGR-OH
Descriptor:Plasminogen activator inhibitor-2, 14-mer from Plasminogen activator inhibitor-2
Authors:Di Giusto, D.A., Sutherland, A.P., Jankova, L., Harrop, S.J., Curmi, P.M., King, G.C.
Deposit date:2005-08-21
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities
J.Mol.Biol., 353, 2005
2ARR
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HUMAN PLASMINOGEN ACTIVATOR INHIBITOR-2.[LOOP (66-98) DELETION MUTANT] COMPLEXED WITH PEPTIDE N-ACETYL-TEAAAGMGGVMTGR-OH
Descriptor:Plasminogen activator inhibitor-2, 14-mer from Plasminogen activator inhibitor-2
Authors:Di Giusto, D.A., Sutherland, A.P., Jankova, L., Harrop, S.J., Curmi, P.M., King, G.C.
Deposit date:2005-08-21
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities
J.Mol.Biol., 353, 2005
3AQ1
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OPEN STATE MONOMER OF A GROUP II CHAPERONIN FROM METHANOCOCCOIDES BURTONII
Descriptor:Thermosome subunit
Authors:Harrop, S.J., Pilak, O., Siddiqui, K.S., De Francisci, D., Burg, D., Williams, T.J., Cavicchioli, R., Curmi, P.M.
Deposit date:2010-10-24
Release date:2011-09-14
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:Chaperonins from an Antarctic archaeon are predominantly monomeric: crystal structure of an open state monomer.
ENVIRON.MICROBIOL., 13, 2011
3U8B
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FUNCTIONALLY SELECTIVE INHIBITION OF GROUP IIA PHOSPHOLIPASE A2 REVEALS A ROLE FOR VIMENTIN IN REGULATING ARACHIDONIC ACID METABOLISM
Descriptor:Phospholipase A2, membrane associated, CHLORIDE ION, ...
Authors:Lee, L.K., Bryant, K.J., Bouveret, R., Lei, P.-W., Duff, A.P., Harrop, S.J., Huang, E.P., Harvey, R.P., Gelb, M.H., Gray, P.P., Curmi, P.M., Cunningham, A.M., Church, W.B., Scott, K.F.
Deposit date:2011-10-16
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3U8D
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FUNCTIONALLY SELECTIVE INHIBITION OF GROUP IIA PHOSPHOLIPASE A2 REVEALS A ROLE FOR VIMENTIN IN REGULATING ARACHIDONIC ACID METABOLISM
Descriptor:Phospholipase A2, membrane associated, (3-{[3-(2-amino-2-oxoethyl)-1-benzyl-2-ethyl-1H-indol-5-yl]oxy}propyl)phosphonic acid, ...
Authors:Lee, L.K., Bryant, K.J., Bouveret, R., Lei, P.-W., Duff, A.P., Harrop, S.J., Huang, E.P., Harvey, R.P., Gelb, M.H., Gray, P.P., Curmi, P.M., Cunningham, A.M., Church, W.B., Scott, K.F.
Deposit date:2011-10-16
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3U8H
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FUNCTIONALLY SELECTIVE INHIBITION OF GROUP IIA PHOSPHOLIPASE A2 REVEALS A ROLE FOR VIMENTIN IN REGULATING ARACHIDONIC ACID METABOLISM
Descriptor:Phospholipase A2, membrane associated, (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID, ...
Authors:Lee, L.K., Bryant, K.J., Bouveret, R., Lei, P.-W., Duff, A.P., Harrop, S.J., Huang, E.P., Harvey, R.P., Gelb, M.H., Gray, P.P., Curmi, P.M., Cunningham, A.M., Church, W.B., Scott, K.F.
Deposit date:2011-10-17
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3U8I
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FUNCTIONALLY SELECTIVE INHIBITION OF GROUP IIA PHOSPHOLIPASE A2 REVEALS A ROLE FOR VIMENTIN IN REGULATING ARACHIDONIC ACID METABOLISM
Descriptor:Phospholipase A2, membrane associated, CALCIUM ION, ...
Authors:Lee, L.K., Bryant, K.J., Bouveret, R., Lei, P.-W., Duff, A.P., Harrop, S.J., Huang, E.P., Harvey, R.P., Gelb, M.H., Gray, P.P., Curmi, P.M., Cunningham, A.M., Church, W.B., Scott, K.F.
Deposit date:2011-10-17
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3RUB
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CRYSTAL STRUCTURE OF THE UNACTIVATED FORM OF RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE FROM TOBACCO REFINED AT 2.0-ANGSTROMS RESOLUTION
Descriptor:RIBULOSE 1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE, FORM III, SULFATE ION, ...
Authors:Schreuder, H., Cascio, D., Curmi, P.M.G., Chapman, M.S., Suh, S.W., Eisenberg, D.S.
Deposit date:1990-05-25
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the unactivated form of ribulose-1,5-bisphosphate carboxylase/oxygenase from tobacco refined at 2.0-A resolution.
J.Biol.Chem., 267, 1992
1BY7
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HUMAN PLASMINOGEN ACTIVATOR INHIBITOR-2. LOOP (66-98) DELETION MUTANT
Descriptor:PROTEIN (PLASMINOGEN ACTIVATOR INHIBITOR-2)
Authors:Harrop, S.J., King, G.C., Mabbutt, B.C., Curmi, P.M.G.
Deposit date:1998-10-27
Release date:1999-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of plasminogen activator inhibitor 2 at 2.0 A resolution: implications for serpin function.
Structure Fold.Des., 7, 1999
1I81
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CRYSTAL STRUCTURE OF A HEPTAMERIC LSM PROTEIN FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
Descriptor:PUTATIVE SNRNP SM-LIKE PROTEIN
Authors:Collins, B.M., Harrop, S.J., Kornfeld, G.D., Dawes, I.W., Curmi, P.M.G., Mabbutt, B.C.
Deposit date:2001-03-12
Release date:2001-03-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a heptameric Sm-like protein complex from archaea: implications for the structure and evolution of snRNPs.
J.Mol.Biol., 309, 2001
1K0M
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CRYSTAL STRUCTURE OF A SOLUBLE MONOMERIC FORM OF CLIC1 AT 1.4 ANGSTROMS
Descriptor:CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1
Authors:Harrop, S.J., DeMaere, M.Z., Fairlie, W.D., Reztsova, T., Valenzuela, S.M., Mazzanti, M., Tonini, R., Qiu, M.R., Jankova, L., Warton, K., Bauskin, A.R., Wu, W.M., Pankhurst, S., Campbell, T.J., Breit, S.N., Curmi, P.M.G.
Deposit date:2001-09-19
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
J.Biol.Chem., 276, 2001
1K0N
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CHLORIDE INTRACELLULAR CHANNEL 1 (CLIC1) COMPLEXED WITH GLUTATHIONE
Descriptor:CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1, GLUTATHIONE
Authors:Harrop, S.J., DeMaere, M.Z., Fairlie, W.D., Reztsova, T., Valenzuela, S.M., Mazzanti, M., Tonini, R., Qiu, M.R., Jankova, L., Warton, K., Bauskin, A.R., Wu, W.M., Pankhurst, S., Campbell, T.J., Breit, S.N., Curmi, P.M.G.
Deposit date:2001-09-19
Release date:2001-12-12
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
J.Biol.Chem., 276, 2001
1K0O
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CRYSTAL STRUCTURE OF A SOLUBLE FORM OF CLIC1. AN INTRACELLULAR CHLORIDE ION CHANNEL
Descriptor:CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1
Authors:Harrop, S.J., DeMaere, M.Z., Fairlie, W.D., Reztsova, T., Valenzuela, S.M., Mazzanti, M., Tonini, R., Qiu, M.R., Jankova, L., Warton, K., Bauskin, A.R., Wu, W.M., Pankhurst, S., Campbell, T.J., Breit, S.N., Curmi, P.M.G.
Deposit date:2001-09-19
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
J.Biol.Chem., 276, 2001
1QGW
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CRYSTAL STRUCTURE OF PHYCOERYTHRIN 545 FROM THE MARINE CRYPTOPHYTE RHODOMONAS CS24
Descriptor:PROTEIN (CRYPTOPHYTAN PHYCOERYTHRIN (ALPHA-1 CHAIN)), PROTEIN (CRYPTOPHYTAN PHYCOERYTHRIN (ALPHA-2 CHAIN)), PROTEIN (CRYPTOPHYTAN PHYCOERYTHRIN (BETA CHAIN)), ...
Authors:Harrop, S.J., Wilk, K.E., Hiller, R.G., Curmi, P.M.G.
Deposit date:1999-05-10
Release date:1999-05-19
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Evolution of a light-harvesting protein by addition of new subunits and rearrangement of conserved elements: crystal structure of a cryptophyte phycoerythrin at 1.63-A resolution.
Proc.Natl.Acad.Sci.USA, 96, 1999
2Q5Z
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CRYSTAL STRUCTURE OF IMAZG FROM VIBRIO DAT 722: NTAG-IMAZG (P43212)
Descriptor:Hypothetical protein, MAGNESIUM ION, GLYCEROL
Authors:Robinson, A., Guilfoyle, A.P., Harrop, S.J., Boucher, Y., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C.
Deposit date:2007-06-04
Release date:2007-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A putative house-cleaning enzyme encoded within an integron array: 1.8 A crystal structure defines a new MazG subtype.
Mol.Microbiol., 66, 2007
2Q73
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CRYSTAL STRUCTURE OF IMAZG FROM VIBRIO DAT 722: CTAG-IMAZG (P41212)
Descriptor:Hypothetical protein, MAGNESIUM ION
Authors:Robinson, A., Guilfoyle, A.P., Harrop, S.J., Boucher, Y., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C.
Deposit date:2007-06-05
Release date:2007-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A putative house-cleaning enzyme encoded within an integron array: 1.8 A crystal structure defines a new MazG subtype.
Mol.Microbiol., 66, 2007
2Q9L
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CRYSTAL STRUCTURE OF IMAZG FROM VIBRIO DAT 722: CTAG-IMAZG (P43212)
Descriptor:Hypothetical protein, MAGNESIUM ION
Authors:Robinson, A., Guilfoyle, A.P., Harrop, S.J., Boucher, Y., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C.
Deposit date:2007-06-13
Release date:2007-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A putative house-cleaning enzyme encoded within an integron array: 1.8 A crystal structure defines a new MazG subtype.
Mol.Microbiol., 66, 2007
3FXH
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CRYSTAL STRUCTURE FROM THE MOBILE METAGENOME OF HALIFAX HARBOUR SEWAGE OUTFALL: INTEGRON CASSETTE PROTEIN HFX_CASS2
Descriptor:Integron gene cassette protein HFX_CASS2
Authors:Sureshan, V., Deshpande, C., Harrop, S.J., Kudritska, M., Koenig, J.E., Evdokimova, E., Chang, C., Edwards, A.M., Savchenko, A., Joachimiak, A., Doolittle, W.F., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C., Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-01-20
Release date:2009-02-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.837 Å)
Cite:Integron gene cassettes: a repository of novel protein folds with distinct interaction sites.
Plos One, 8, 2013
3FY6
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STRUCTURE FROM THE MOBILE METAGENOME OF V. CHOLERAE. INTEGRON CASSETTE PROTEIN VCH_CASS3
Descriptor:Integron cassette protein
Authors:Deshpande, C.N., Sureshan, V., Harrop, S.J., Boucher, Y., Xu, X., Cui, H., Edwards, A., Savchenko, A., Joachimiak, A., Tan, K., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C., Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-01-21
Release date:2009-02-10
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Integron gene cassettes: a repository of novel protein folds with distinct interaction sites.
Plos One, 8, 2013
3GK6
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CRYSTAL STRUCTURE FROM THE MOBILE METAGENOME OF VIBRIO CHOLERAE. INTEGRON CASSETTE PROTEIN VCH_CASS2.
Descriptor:Integron cassette protein VCH_CASS2, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
Authors:Deshpande, C.N., Sureshan, V., Harrop, S.J., Boucher, Y., Xu, X., Cui, H., Edwards, A.M., Savchenko, A., Joachimiak, A., Chang, C., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C., Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-03-10
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of an Integron Gene Cassette-Associated Protein from Vibrio cholerae Identifies a Cationic Drug-Binding Module.
Plos One, 6, 2011
3I9S
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STRUCTURE FROM THE MOBILE METAGENOME OF V.CHOLERAE. INTEGRON CASSETTE PROTEIN VCH_CASS6
Descriptor:Integron cassette protein, SULFATE ION, CHLORIDE ION
Authors:Deshpande, C.N., Sureshan, V., Harrop, S.J., Boucher, Y., Xu, X., Cui, H., Edwards, A., Savchenko, A., Joachimiak, A., Chang, C., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C., Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-07-13
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure from the mobile metagenome of V.cholerae. Integron cassette protein VCH_CASS6
To be Published
3IF4
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STRUCTURE FROM THE MOBILE METAGENOME OF NORTH WEST ARM SEWAGE OUTFALL: INTEGRON CASSETTE PROTEIN HFX_CASS5
Descriptor:Integron Cassette Protein Hfx_Cass5
Authors:Sureshan, V., Deshpande, C.N., Harrop, S.J., Evdokimova, E., Kudrytska, M., Koenig, J.E., Osipiuk, J., Edwards, A., Savchenko, A., Joachimiak, A., Doolittle, W.F., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C., Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-07-24
Release date:2009-09-08
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (2.181 Å)
Cite:Integron gene cassettes: a repository of novel protein folds with distinct interaction sites.
Plos One, 8, 2013
3JRT
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STRUCTURE FROM THE MOBILE METAGENOME OF V. PARACHOLERAE: INTEGRON CASSETTE PROTEIN VPC_CASS2
Descriptor:Integron cassette protein Vpc_cass2
Authors:Harrop, S.J., Deshpande, C., Sureshan, V., Boucher, Y., Xu, X., Cui, H., Cuff, M., Edwards, A., Savchenko, A., Joachimiak, A., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C., Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-09-08
Release date:2009-09-22
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Integron gene cassettes: a repository of novel protein folds with distinct interaction sites.
Plos One, 8, 2013
4LM6
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LIGHT HARVESTING COMPLEX PC612 FROM THE CRYPTOPHYTE HEMISELMIS VIRESCENS M1635
Descriptor:cryptophyte phycocyanin alpha chain, cryptophyte phycocyanin beta chain, PHYCOCYANOBILIN, ...
Authors:Harrop, S.J., Wilk, K.E., Curmi, P.M.G.
Deposit date:2013-07-10
Release date:2014-06-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Single-residue insertion switches the quaternary structure and exciton states of cryptophyte light-harvesting proteins.
Proc.Natl.Acad.Sci.USA, 111, 2014
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