Author results

1AF8
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ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR A3(2), NMR, 24 STRUCTURES
Descriptor:ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN
Authors:Crump, M.P., Crosby, J., Dempsey, C.E., Parkinson, J.A., Murray, M., Hopwood, D.A., Simpson, T.J.
Deposit date:1997-03-23
Release date:1997-09-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2).
Biochemistry, 36, 1997
1EOT
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SOLUTION NMR STRUCTURE OF EOTAXIN, MINIMIZED AVERAGE STRUCTURE
Descriptor:EOTAXIN
Authors:Crump, M.P., Rajarathnam, K., Sykes, B.D.
Deposit date:1998-06-17
Release date:1999-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
J.Biol.Chem., 273, 1998
1HFF
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NMR SOLUTION STRUCTURES OF THE VMIP-II 1-10 PEPTIDE FROM KAPOSI'S SARCOMA-ASSOCIATED HERPESVIRUS.
Descriptor:VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II
Authors:Crump, M.P., Elisseeva, E., Gong, J.H., Clark-Lewis, I., Sykes, B.D.
Deposit date:2000-12-01
Release date:2000-12-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure/Function of Human Herpesvirus-8 Mip-II (1-71) and the Antagonist N-Terminal Segment (1-10)
FEBS Lett., 489, 2001
1HFG
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NMR SOLUTION STRUCTURE OF VMIP-II 1-71 FROM KAPOSI'S SARCOMA-ASSOCIATED HERPESVIRUS (MINIMIZED AVERAGE STRUCTURE).
Descriptor:VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II
Authors:Crump, M.P., Elisseeva, E., Gong, J.-H., Clark-Lewis, I., Sykes, B.D.
Deposit date:2000-12-01
Release date:2001-01-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure/Function of Human Herpesvirus-8 Mip-II (1-71) and the Antagonist N-Terminal Segment (1-10)
FEBS Lett., 489, 2001
1HFN
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NMR SOLUTION STRUCTURES OF VMIP-II 1-71 FROM KAPOSI'S SARCOMA-ASSOCIATED HERPESVIRUS.
Descriptor:VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II
Authors:Crump, M.P., Elisseeva, E., Gong, J.-H., Clark-Lewis, I., Sykes, B.D.
Deposit date:2000-12-07
Release date:2001-01-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure/Function of Human Herpesvirus-8 Mip-II (1-71) and the Antagonist N-Terminal Segment (1-10)
FEBS Lett., 489, 2001
1RD4
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AN ALLOSTERIC INHIBITOR OF LFA-1 BOUND TO ITS I-DOMAIN
Descriptor:Integrin alpha-L, 1-ACETYL-4-(4-{4-[(2-ETHOXYPHENYL)THIO]-3-NITROPHENYL}PYRIDIN-2-YL)PIPERAZINE
Authors:Crump, M.P., Ceska, T.A., Spyracopoulos, L., Henry, A., Archibald, S.C., Alexander, R., Taylor, R.J., Findlow, S.C., O'Connell, J., Robinson, M.K., Shock, A.
Deposit date:2003-11-05
Release date:2004-03-30
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of an allosteric inhibitor of LFA-1 bound to the I-domain studied by crystallography, NMR, and calorimetry
Biochemistry, 43, 2004
1SDF
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SOLUTION STRUCTURE OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:STROMAL CELL-DERIVED FACTOR-1
Authors:Crump, M.P., Rajarathnam, K., Clark-Lewis, I., Sykes, B.D.
Deposit date:1997-11-15
Release date:1998-01-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.
EMBO J., 16, 1997
2AF8
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ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR A3(2), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN
Authors:Crump, M.P., Crosby, J., Dempsey, C.E., Parkinson, J.A., Murray, M., Hopwood, D.A., Simpson, T.J.
Deposit date:1997-03-23
Release date:1997-09-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2).
Biochemistry, 36, 1997
2EOT
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SOLUTION STRUCTURE OF EOTAXIN, AN ENSEMBLE OF 32 NMR SOLUTION STRUCTURES
Descriptor:EOTAXIN
Authors:Crump, M.P., Rajarathnam, K., Kim, K.-S., Clark-Lewis, I., Sykes, B.D.
Deposit date:1998-06-29
Release date:1998-11-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
J.Biol.Chem., 273, 1998
2SDF
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SOLUTION NMR STRUCTURE OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1), 30 STRUCTURES
Descriptor:STROMAL CELL-DERIVED FACTOR-1
Authors:Crump, M.P., Rajarathnam, K., Clark-Lewis, I., Sykes, B.D.
Deposit date:1998-03-07
Release date:1998-06-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.
EMBO J., 16, 1997
2K0X
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THE ACTINORHODIN HOLO ACYL CARRIER PROTEIN FROM S. COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, 4'-PHOSPHOPANTETHEINE
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2008-02-15
Release date:2008-09-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein.
Chembiochem, 9, 2008
2K0Y
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THE ACTINORHODIN APO ACYL CARRIER PROTEIN FROM S. COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein
Authors:Crump, M.P., Evans, S.E., Christopher, W.
Deposit date:2008-02-15
Release date:2008-09-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein.
Chembiochem, 9, 2008
2KG6
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SOLUTION STRUCTURE OF THE ACETYL ACTINORHODIN ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, THIOACETIC ACID S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL} ESTER
Authors:Crump, M.P., Evans, S.E., Eliza, P., Christopher, W.
Deposit date:2009-03-06
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KG8
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NMR SOLUTION STRUCTURES OF MALONYL ACP FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, 3-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-3-oxopropanoic acid
Authors:Crump, M.P., Evans, S.E., Williams, C., Eliza, P.
Deposit date:2009-03-06
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KG9
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NMR SOLUTION STRUCTURES OF BUTYRYL-ACP (A NON-POLAR, NON PATHWAY INTERMEDIATE) FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, THIOBUTYRIC ACID S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL} ESTER
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-07
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGA
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NMR SOLUTION STRUCTURES OF HEXANOYL ACP (A NON NATURAL INTERMEDIATE) FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-07
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGC
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NMR SOLUTION STRUCTURES OF OCTANOYL ACP (A NON-NATURAL INTERMEDIATE) FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-08
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGD
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NMR SOLUTION STRUCTURES OF 3-OXO-BUTYL-ACP, AN INTERMEDIATE MIMIC FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(3-oxobutyl)sulfanyl]ethyl}-beta-alaninamide
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-08
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGE
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NMR SOLUTION STRUCTURES OF 3,5-DIOXOHEXYL ACP (A TRIKETIDE MIMIC) FROM THE ACTINORHODIN POLYKETIDE SYNTHASE IN STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, N-{2-[(3,5-dioxohexyl)sulfanyl]ethyl}-N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide
Authors:Crump, M.P., Evans, S.E., Williams, C.
Deposit date:2009-03-08
Release date:2009-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
1A93
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NMR SOLUTION STRUCTURE OF THE C-MYC-MAX HETERODIMERIC LEUCINE ZIPPER, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:MYC PROTO-ONCOGENE PROTEIN, MAX PROTEIN
Authors:Lavigne, P., Crump, M.P., Gagne, S.M., Hodges, R.S., Kay, C.M., Sykes, B.D.
Deposit date:1998-04-15
Release date:1998-10-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper.
J.Mol.Biol., 281, 1998
1EL0
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SOLUTION STRUCTURE OF THE HUMAN CC CHEMOKINE, I-309
Descriptor:I-309
Authors:Keizer, D.W., Crump, M.P., Lee, T.W., Slupsky, C.M., Clark-Lewis, I., Sykes, B.D.
Deposit date:2000-03-11
Release date:2000-09-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Human CC chemokine I-309, structural consequences of the additional disulfide bond.
Biochemistry, 39, 2000
1GVT
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ENDOTHIAPEPSIN COMPLEX WITH CP-80,794
Descriptor:ENDOTHIAPEPSIN, N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R,2S)-1-(cyclohexylmethyl)-2-hydroxy-3-(1-methylethoxy)-3-oxopropyl]-S-methyl-L-cysteinamide, SULFATE ION
Authors:Coates, L., Erskine, P.T., Crump, M.P., Wood, S.P., Cooper, J.B.
Deposit date:2002-02-27
Release date:2002-07-04
Last modified:2012-11-30
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism
J.Mol.Biol., 318, 2002
1GVU
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ENDOTHIAPEPSIN COMPLEX WITH H189
Descriptor:ENDOTHIAPEPSIN, INHIBITOR, H189, ...
Authors:Coates, L., Erskine, P.T., Crump, M.P., Wood, S.P., Cooper, J.B.
Deposit date:2002-02-27
Release date:2002-07-04
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (0.94 Å)
Cite:Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism
J.Mol.Biol., 318, 2002
1GVV
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FIVE ATOMIC RESOLUTION STRUCTURES OF ENDOTHIAPEPSIN INHIBITOR COMPLEXES; IMPLICATIONS FOR THE ASPARTIC PROTEINASE MECHANISM
Descriptor:ENDOTHIAPEPSIN, N-[(5S,9S,10S,13S)-9-hydroxy-5,10-bis(2-methylpropyl)-4,7,12,16-tetraoxo-3,6,11,17-tetraazabicyclo[17.3.1]tricosa-1(23),19,21-trien-13-yl]-3-(naphthalen-1-yl)-2-(naphthalen-1-ylmethyl)propanamide, SULFATE ION
Authors:Coates, L., Erskine, P.T., Crump, M.P., Wood, S.P., Cooper, J.B.
Deposit date:2002-02-27
Release date:2002-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism
J.Mol.Biol., 318, 2002
1GVW
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ENDOTHIAPEPSIN COMPLEX WITH PD-130,328
Descriptor:ENDOTHIAPEPSIN, N-(tert-butoxycarbonyl)-L-phenylalanyl-N-{(1S)-1-[(R)-hydroxy(2-{[(2S)-2-methylbutyl]amino}-2-oxoethyl)phosphoryl]-3-methylbutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide, SULFATE ION
Authors:Coates, L., Erskine, P.T., Crump, M.P., Wood, S.P., Cooper, J.B.
Deposit date:2002-02-27
Release date:2002-07-04
Last modified:2012-11-30
Method:X-RAY DIFFRACTION (1 Å)
Cite:Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism
J.Mol.Biol., 318, 2002