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3DEG
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BU of 3deg by Molmil
Complex of elongating Escherichia coli 70S ribosome and EF4(LepA)-GMPPNP
Descriptor: 30S RNA helix 14, 30S RNA helix 8, 30S ribosomal protein S12, ...
Authors:Connell, S.R, Topf, M, Qin, Y, Wilson, D.N, Mielke, T, Fucini, P, Nierhaus, K.H, Spahn, C.M.T.
Deposit date:2008-06-10
Release date:2008-08-19
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (10.9 Å)
Cite:A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
Nat.Struct.Mol.Biol., 15, 2008
2OM7
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BU of 2om7 by Molmil
Structural Basis for Interaction of the Ribosome with the Switch Regions of GTP-bound Elongation Factors
Descriptor: 16S ribosomal RNA (H5), 30S ribosomal protein S12, 30S ribosomal protein S2, ...
Authors:Connell, S.R, Wilson, D.N, Rost, M, Schueler, M, Giesebrecht, J, Dabrowski, M, Mielke, T, Fucini, P, Spahn, C.M.T.
Deposit date:2007-01-21
Release date:2008-01-15
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.
Mol.Cell, 25, 2007
8C0B
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BU of 8c0b by Molmil
CryoEM structure of Aspergillus nidulans UTP-glucose-1-phosphate uridylyltransferase
Descriptor: UTP--glucose-1-phosphate uridylyltransferase
Authors:Han, X, D Angelo, C, Otamendi, A, Cifuente, J.O, de Astigarraga, E, Ochoa-Lizarralde, B, Grininger, M, Routier, F.H, Guerin, M.E, Fuehring, J, Etxebeste, O, Connell, S.R.
Deposit date:2022-12-16
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:Molecular mechanism of UDP-Glc biosynthesis by the essential UDP-Glc pyrophosphorylase from Aspergillus nidulans
To Be Published
4V8V
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BU of 4v8v by Molmil
Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex
Descriptor: FLAVIN MONONUCLEOTIDE, TYPE-I FATTY ACID SYNTHASE
Authors:Ciccarelli, L, Connell, S.R, Enderle, M, Mills, D.J, Vonck, J, Grininger, M.
Deposit date:2013-04-18
Release date:2014-07-09
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex.
Structure, 21, 2013
4V8W
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BU of 4v8w by Molmil
Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex
Descriptor: FLAVIN MONONUCLEOTIDE, TYPE-I FATTY ACID SYNTHASE
Authors:Ciccarelli, L, Connell, S.R, Enderle, M, Mills, D.J, Vonck, J, Grininger, M.
Deposit date:2013-04-18
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (17.5 Å)
Cite:Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex.
Structure, 21, 2013
4V5N
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BU of 4v5n by Molmil
tRNA translocation on the 70S ribosome: the post- translocational translocation intermediate TI(POST)
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T.
Deposit date:2010-10-21
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
2ZJR
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BU of 2zjr by Molmil
Refined native structure of the large ribosomal subunit (50S) from Deinococcus radiodurans
Descriptor: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P.
Deposit date:2008-03-08
Release date:2008-06-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
2ZJQ
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BU of 2zjq by Molmil
Interaction of L7 with L11 induced by Microccocin binding to the Deinococcus radiodurans 50S subunit
Descriptor: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P.
Deposit date:2008-03-08
Release date:2008-06-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
2ZJP
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BU of 2zjp by Molmil
Thiopeptide antibiotic Nosiheptide bound to the large ribosomal subunit of Deinococcus radiodurans
Descriptor: 4-(hydroxymethyl)-3-methyl-1H-indole-2-carboxylic acid, 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, ...
Authors:Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P.
Deposit date:2008-03-07
Release date:2008-06-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
4V5M
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BU of 4v5m by Molmil
tRNA tranlocation on the 70S ribosome: the pre-translocational translocation intermediate TI(PRE)
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T.
Deposit date:2010-10-01
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
3CF5
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BU of 3cf5 by Molmil
Thiopeptide antibiotic Thiostrepton bound to the large ribosomal subunit of Deinococcus radiodurans
Descriptor: 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, 50S RIBOSOMAL PROTEIN L14, ...
Authors:Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P.
Deposit date:2008-03-02
Release date:2008-06-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
3DLL
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BU of 3dll by Molmil
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Descriptor: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Wilson, D.N, Schluenzen, F, Harms, J.M, Starosta, A.L, Connell, S.R, Fucini, P.
Deposit date:2008-06-27
Release date:2008-09-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
5NO3
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BU of 5no3 by Molmil
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate without uS3)
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-31
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5NO4
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BU of 5no4 by Molmil
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate with uS3)
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-31
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5NO2
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BU of 5no2 by Molmil
RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate)
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-24
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5DM6
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BU of 5dm6 by Molmil
Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
Authors:Kaminishi, T, Schedlbauer, A, Ochoa-Lizarralde, B, Connell, S.R, Fucini, P.
Deposit date:2015-09-08
Release date:2015-11-11
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
5DM7
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BU of 5dm7 by Molmil
Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with hygromycin A
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
Authors:Kaminishi, T, Schedlbauer, A, Ochoa-Lizarralde, B, Connell, S.R, Fucini, P.
Deposit date:2015-09-08
Release date:2015-11-11
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
5IWA
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BU of 5iwa by Molmil
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic
Descriptor: (2S,3S)-2-{[(2S)-3-(2-amino-1H-imidazol-5-yl)-2-{[(2S,4S)-5-(carbamoyloxy)-4-hydroxy-2-({[(2S,3S)-3-hydroxypiperidin-2-yl]carbonyl}amino)pentanoyl]amino}propanoyl]amino}-3-(2-chloro-1H-imidazol-5-yl)-3-hydroxypropanoic acid, 16S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Chieko, N, Masahito, K, Takemoto, C, Yokoyama, S, Connell, S.R, Fucini, P.
Deposit date:2016-03-22
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.
Proc.Natl.Acad.Sci.USA, 113, 2016
4YHH
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BU of 4yhh by Molmil
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Dhimole, N, Zhou, S, Lopez-Alonso, J.P, Connell, S.R, Fucini, P.
Deposit date:2015-02-27
Release date:2015-04-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.417 Å)
Cite:Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Antimicrob.Agents Chemother., 59, 2015
2NOQ
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BU of 2noq by Molmil
Structure of ribosome-bound cricket paralysis virus IRES RNA
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S5, ...
Authors:Schuler, M, Connell, S.R, Lescoute, A, Giesebrecht, J, Dabrowski, M, Schroeer, B, Mielke, T, Penczek, P.A, Westhof, E, Spahn, C.M.T.
Deposit date:2006-10-26
Release date:2006-11-21
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structure of the ribosome-bound cricket paralysis virus IRES RNA.
Nat.Struct.Mol.Biol., 13, 2006
7AF3
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BU of 7af3 by Molmil
Bacterial 30S ribosomal subunit assembly complex state M (head domain)
Descriptor: 16S rRNA (head), 30S ribosomal protein S10, 30S ribosomal protein S13, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.R.
Deposit date:2020-09-19
Release date:2021-07-07
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7BOD
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BU of 7bod by Molmil
Bacterial 30S ribosomal subunit assembly complex state M (body domain)
Descriptor: 16S rRNA (body domain of 30S subunit), 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.R.
Deposit date:2021-01-25
Release date:2021-07-07
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7BOE
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BU of 7boe by Molmil
Bacterial 30S ribosomal subunit assembly complex state M (Consensus refinement)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.R.
Deposit date:2021-01-25
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7NAS
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BU of 7nas by Molmil
Bacterial 30S ribosomal subunit assembly complex state A (multibody refinement for body domain of 30S ribosome)
Descriptor: 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-07-07
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7NAR
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BU of 7nar by Molmil
Complete Bacterial 30S ribosomal subunit assembly complex state F (+RsgA)(Consensus Refinement)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021

 

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