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8V3K
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BU of 8v3k by Molmil
F95S-F198S epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation
Descriptor: DIPHOSPHATE, Epi-isozizaene synthase, GLYCEROL, ...
Authors:Christianson, D.W, Eaton, S.A.
Deposit date:2023-11-28
Release date:2024-01-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structure-Based Engineering of a Sesquiterpene Cyclase to Generate an Alcohol Product: Conversion of epi-Isozizaene Synthase into alpha-Bisabolol Synthase.
Biochemistry, 2024
6V0K
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BU of 6v0k by Molmil
Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain
Descriptor: GLYCEROL, Terpene synthase
Authors:Christianson, D.W, Ronnebaum, T.A.
Deposit date:2019-11-18
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Higher-order oligomerization of a chimeric alpha beta gamma bifunctional diterpene synthase with prenyltransferase and class II cyclase activities is concentration-dependent.
J.Struct.Biol., 210, 2020
2NMX
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BU of 2nmx by Molmil
Structure of inhibitor binding to Carbonic Anhydrase I
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 1, N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE, ...
Authors:Christianson, D.W, Jude, K.M.
Deposit date:2006-10-23
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II
J.Am.Chem.Soc., 129, 2007
2NNV
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BU of 2nnv by Molmil
Structure of inhibitor binding to Carbonic Anhydrase II
Descriptor: Carbonic anhydrase 2, ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE, GLYCEROL, ...
Authors:Christianson, D.W, Jude, K.M.
Deposit date:2006-10-24
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
J.Am.Chem.Soc., 129, 2007
2NN7
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BU of 2nn7 by Molmil
Structure of inhibitor binding to Carbonic Anhydrase I
Descriptor: Carbonic anhydrase 1, DIMETHYL SULFOXIDE, ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE, ...
Authors:Christianson, D.W, Jude, K.M.
Deposit date:2006-10-23
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
J.Am.Chem.Soc., 129, 2007
2NNG
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BU of 2nng by Molmil
Structure of inhibitor binding to Carbonic Anhydrase II
Descriptor: 4-(2-AMINOETHYL)BENZENESULFONAMIDE, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Christianson, D.W, Jude, K.M.
Deposit date:2006-10-24
Release date:2007-05-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
J.Am.Chem.Soc., 129, 2007
2NNS
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BU of 2nns by Molmil
Structure of inhibitor binding to Carbonic Anhydrase II
Descriptor: CHLORIDE ION, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Christianson, D.W, Jude, K.M.
Deposit date:2006-10-24
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
J.Am.Chem.Soc., 129, 2007
2NNO
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BU of 2nno by Molmil
Structure of inhibitor binding to Carbonic Anhydrase II
Descriptor: 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Christianson, D.W, Jude, K.M.
Deposit date:2006-10-24
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II.
J.Am.Chem.Soc., 129, 2007
2NN1
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BU of 2nn1 by Molmil
Structure of inhibitor binding to Carbonic Anhydrase I
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID, Carbonic anhydrase 1, ...
Authors:Christianson, D.W, Jude, K.M.
Deposit date:2006-10-23
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II
J.Am.Chem.Soc., 129, 2007
7CA2
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BU of 7ca2 by Molmil
ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II
Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION
Authors:Nair, S.K, Christianson, D.W.
Deposit date:1991-07-09
Release date:1992-07-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Engineering the hydrophobic pocket of carbonic anhydrase II.
Biochemistry, 30, 1991
5RLA
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BU of 5rla by Molmil
ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION
Descriptor: ARGINASE, MANGANESE (II) ION
Authors:Scolnick, L.R, Kanyo, Z.F, Christianson, D.W.
Deposit date:1997-05-07
Release date:1998-05-13
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function.
Biochemistry, 36, 1997
5THS
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BU of 5ths by Molmil
Crystal Structure of G302A HDAC8 in complex with M344
Descriptor: 1,2-ETHANEDIOL, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, ...
Authors:Porter, N.J, Christianson, D.W.
Deposit date:2016-09-30
Release date:2016-12-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Biochemistry, 55, 2016
5THU
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BU of 5thu by Molmil
Crystal Structure of G304A HDAC8 in complex with M344
Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, POTASSIUM ION, ...
Authors:Porter, N.J, Christianson, D.W.
Deposit date:2016-09-30
Release date:2016-12-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Biochemistry, 55, 2016
5THV
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BU of 5thv by Molmil
Crystal Structure of G305A HDAC8 in complex with M344
Descriptor: 1,2-ETHANEDIOL, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, ...
Authors:Porter, N.J, Christianson, D.W.
Deposit date:2016-09-30
Release date:2016-12-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.868 Å)
Cite:Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Biochemistry, 55, 2016
5THT
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BU of 5tht by Molmil
Crystal Structure of G303A HDAC8 in complex with M344
Descriptor: 1,2-ETHANEDIOL, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, ...
Authors:Porter, N.J, Christianson, D.W.
Deposit date:2016-09-30
Release date:2016-12-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.407 Å)
Cite:Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Biochemistry, 55, 2016
4ZUO
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BU of 4zuo by Molmil
Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
Descriptor: 6-[(3-aminopropyl)amino]-N-hydroxyhexanamide, AMMONIUM ION, Acetylpolyamine aminohydrolase, ...
Authors:Decroos, C, Christianson, D.W.
Deposit date:2015-05-17
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase.
Biochemistry, 54, 2015
4ZUM
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BU of 4zum by Molmil
Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a trifluoromethylketone inhibitor
Descriptor: 7-[(3-aminopropyl)amino]-1,1,1-trifluoroheptane-2,2-diol, Acetylpolyamine aminohydrolase, GLYCEROL, ...
Authors:Decroos, C, Christianson, D.W.
Deposit date:2015-05-17
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase.
Biochemistry, 54, 2015
4ZUP
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BU of 4zup by Molmil
Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
Descriptor: 5-amino-N-hydroxypentanamide, Acetylpolyamine aminohydrolase, GLYCEROL, ...
Authors:Decroos, C, Christianson, D.W.
Deposit date:2015-05-17
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.421 Å)
Cite:Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase.
Biochemistry, 54, 2015
4ZUN
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BU of 4zun by Molmil
Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a thiol inhibitor
Descriptor: 5-[(3-aminopropyl)amino]pentane-1-thiol, Acetylpolyamine aminohydrolase, GLYCEROL, ...
Authors:Decroos, C, Christianson, D.W.
Deposit date:2015-05-17
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase.
Biochemistry, 54, 2015
4ZUQ
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BU of 4zuq by Molmil
Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
Descriptor: 6-amino-N-hydroxyhexanamide, Acetylpolyamine aminohydrolase, GLYCEROL, ...
Authors:Decroos, C, Christianson, D.W.
Deposit date:2015-05-17
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase.
Biochemistry, 54, 2015
4ZUR
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BU of 4zur by Molmil
Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
Descriptor: 7-amino-N-hydroxyheptanamide, AMMONIUM ION, Acetylpolyamine aminohydrolase, ...
Authors:Decroos, C, Christianson, D.W.
Deposit date:2015-05-17
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase.
Biochemistry, 54, 2015
1AS4
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BU of 1as4 by Molmil
CLEAVED ANTICHYMOTRYPSIN A349R
Descriptor: ACETATE ION, ANTICHYMOTRYPSIN
Authors:Lukacs, C.M, Christianson, D.W.
Deposit date:1997-08-12
Release date:1998-02-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction.
Biochemistry, 37, 1998
1A42
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BU of 1a42 by Molmil
HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH BRINZOLAMIDE
Descriptor: (4R)-2-(2-ethoxyethyl)-4-(ethylamino)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
Authors:Boriack-Sjodin, P.A, Christianson, D.W.
Deposit date:1998-02-10
Release date:1999-03-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination.
Protein Sci., 7, 1998
2ZNC
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BU of 2znc by Molmil
MURINE CARBONIC ANHYDRASE IV
Descriptor: CARBONIC ANHYDRASE IV, ZINC ION
Authors:Stams, T, Chen, Y, Christianson, D.W.
Deposit date:1998-02-10
Release date:1999-03-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination.
Protein Sci., 7, 1998
8EAX
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BU of 8eax by Molmil
Octameric prenyltransferase domain of fusicoccadiene Synthase with C2 symmetry sans transiently associating cyclase domains
Descriptor: Fusicoccadiene synthase
Authors:Faylo, J.L, van Eeuwen, T, Christianson, D.W.
Deposit date:2022-08-29
Release date:2022-11-02
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Transient Prenyltransferase-Cyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase.
Biochemistry, 61, 2022

217705

PDB entries from 2024-03-27

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