Author results

4E17
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ALPHA-E-CATENIN IS AN AUTOINHIBITED MOLECULE THAT CO-ACTIVATES VINCULIN
Descriptor:Vinculin, Catenin alpha-1
Authors:Choi, H.-J., Pokutta, S., Cadwell, G.W., Bankston, L.A., Liddington, R.C., Weis, W.I.
Deposit date:2012-03-05
Release date:2012-05-16
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
4E18
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ALPHA-E-CATENIN IS AN AUTOINHIBITED MOLECULE THAT CO-ACTIVATES VINCULIN
Descriptor:Vinculin, Catenin alpha-1
Authors:Choi, H.-J., Pokutta, S., Cadwell, G.W., Bankston, L.A., Liddington, R.C., Weis, W.I.
Deposit date:2012-03-05
Release date:2012-05-16
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
1PRX
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HORF6 A NOVEL HUMAN PEROXIDASE ENZYME
Descriptor:HORF6
Authors:Choi, H.-J., Kang, S.W., Yang, C.-H., Rhee, S.G., Ryu, S.-E.
Deposit date:1998-04-03
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a novel human peroxidase enzyme at 2.0 A resolution.
Nat.Struct.Biol., 5, 1998
3IFQ
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INTERCTION OF PLAKOGLOBIN AND BETA-CATENIN WITH DESMOSOMAL CADHERINS
Descriptor:plakoglobin, E-cadherin, SULFATE ION
Authors:Choi, H.-J., Gross, J.C., Pokutta, S., Weis, W.I.
Deposit date:2009-07-24
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes.
J.Biol.Chem., 284, 2009
3R6N
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CRYSTAL STRUCTURE OF A RIGID FOUR SPECTRIN REPEAT FRAGMENT OF THE HUMAN DESMOPLAKIN PLAKIN DOMAIN
Descriptor:Desmoplakin, (4S,5S)-1,2-DITHIANE-4,5-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:Choi, H.-J., Weis, W.I.
Deposit date:2011-03-22
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of a rigid four-spectrin-repeat fragment of the human desmoplakin plakin domain.
J.Mol.Biol., 409, 2011
4R0Z
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A CONSERVED PHOSPHORYLATION SWITCH CONTROLS THE INTERACTION BETWEEN CADHERIN AND BETA-CATENIN IN VITRO AND IN VIVO
Descriptor:Protein humpback-2, FORMIC ACID
Authors:Choi, H.-J., Loveless, T., Lynch, A., Bang, I., Hardin, J., Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
4R10
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A CONSERVED PHOSPHORYLATION SWITCH CONTROLS THE INTERACTION BETWEEN CADHERIN AND BETA-CATENIN IN VITRO AND IN VIVO
Descriptor:Protein humpback-2, Cadherin-related hmr-1, SULFATE ION, ...
Authors:Choi, H.-J., Loveless, T., Lynch, A., Bang, I., Hardin, J., Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
4R11
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A CONSERVED PHOSPHORYLATION SWITCH CONTROLS THE INTERACTION BETWEEN CADHERIN AND BETA-CATENIN IN VITRO AND IN VIVO
Descriptor:Protein humpback-2, Cadherin-related hmr-1, IODIDE ION
Authors:Choi, H.-J., Loveless, T., Lynch, A., Bang, I., Hardin, J., Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
5DZZ
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STRUCTURAL CHARACTERIZATION OF INTERMEDIATE FILAMENTS BINDING DOMAIN OF DESMOPLAKIN
Descriptor:Desmoplakin
Authors:Choi, H.-J., Weis, W.I.
Deposit date:2015-09-26
Release date:2016-03-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Intermediate Filament-Binding Region of Desmoplakin.
Plos One, 11, 2016
1ATU
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UNCLEAVED ALPHA-1-ANTITRYPSIN
Descriptor:ALPHA-1-ANTITRYPSIN
Authors:Ryu, S.-E., Choi, H.-J.
Deposit date:1997-05-11
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A.
Structure, 4, 1996
3KJ6
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CRYSTAL STRUCTURE OF A METHYLATED BETA2 ADRENERGIC RECEPTOR-FAB COMPLEX
Descriptor:Beta-2 adrenergic receptor, Fab light chain, Fab heavy chain, ...
Authors:Bokoch, M.P., Zou, Y., Rasmussen, S.G.F., Liu, C.W., Nygaard, R., Rosenbaum, D.M., Fung, J.J., Choi, H.-J., Thian, F.S., Kobilka, T.S., Puglisi, J.D., Weis, W.I., Pardo, L., Prosser, S., Mueller, L., Kobilka, B.K.
Deposit date:2009-11-02
Release date:2010-02-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature, 463, 2010
3P0G
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STRUCTURE OF A NANOBODY-STABILIZED ACTIVE STATE OF THE BETA2 ADRENOCEPTOR
Descriptor:Beta-2 adrenergic receptor, Lysozyme, Camelid Antibody Fragment, ...
Authors:Rasmussen, S.G.F., Choi, H.-J., Fung, J.J., Pardon, E., Casarosa, P., Chae, P.S., DeVree, B.T., Rosenbaum, D.M., Thian, F.S., Kobilka, T.S., Schnapp, A., Konetzki, I., Sunahara, R.K., Gellman, S.H., Pautsch, A., Steyaert, J., Weis, W.I., Kobilka, B.K.
Deposit date:2010-09-28
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a nanobody-stabilized active state of the b2 adrenoceptor
Nature, 469, 2011
3PDS
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IRREVERSIBLE AGONIST-BETA2 ADRENOCEPTOR COMPLEX
Descriptor:Fusion protein Beta-2 adrenergic receptor/Lysozyme, 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one, CHOLESTEROL, ...
Authors:Rosenbaum, D.M., Zhang, C., Lyons, J.A., Holl, R., Aragao, D., Arlow, D.H., Rasmussen, S.G.F., Choi, H.-J., DeVree, B.T., Sunahara, R.K., Chae, P.S., Gellman, S.H., Dror, R.O., Shaw, D.E., Weis, W.I., Caffrey, M., Gmeiner, P., Kobilka, B.K.
Deposit date:2010-10-24
Release date:2011-01-12
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure and function of an irreversible agonist-beta(2) adrenoceptor complex
Nature, 469, 2011
3S2K
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STRUCTURAL BASIS OF WNT SIGNALING INHIBITION BY DICKKOPF BINDING TO LRP5/6.
Descriptor:Low-density lipoprotein receptor-related protein 6, Dickkopf-related protein 1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ahn, V.E., Chu, M.L.-H., Choi, H.-J., Tran, D., Abo, A., Weis, W.I.
Deposit date:2011-05-16
Release date:2011-11-02
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6.
Dev.Cell, 21, 2011
4KRR
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CRYSTAL STRUCTURE OF DROSOPHILA WNTD N-TERMINAL DOMAIN-LINKER (RESIDUES 31-240)
Descriptor:Wnt inhibitor of Dorsal protein, GLYCEROL, SODIUM ION
Authors:Chu, M.L.-H., Choi, H.-J., Ahn, V.E., Daniels, D.L., Nusse, R., Weis, W.I.
Deposit date:2013-05-16
Release date:2013-07-10
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.124 Å)
Cite:Structural Studies of Wnts and Identification of an LRP6 Binding Site.
Structure, 21, 2013
4ONS
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STRUCTURAL AND THERMODYNAMIC CHARACTERIZATION OF CADHERIN-BETA-CATENIN-ALPHA-CATENIN COMPLEX FORMATION
Descriptor:Catenin alpha-2, Catenin beta-1
Authors:Pokutta, S., Choi, H.-J., Ahlsen, G., Hansen, S.D., Weis, W.I.
Deposit date:2014-01-29
Release date:2014-04-09
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Thermodynamic Characterization of Cadherin beta-Catenin alpha-Catenin Complex Formation.
J.Biol.Chem., 289, 2014