Author results

2OS5
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MACROPHAGE MIGRATION INHIBITORY FACTOR FROM ANCYLOSTOMA CEYLANICUM
Descriptor:AceMIF, SULFATE ION
Authors:Cho, Y., Lolis, E.
Deposit date:2007-02-05
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional characterization of a secreted hookworm Macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74.
J.Biol.Chem., 282, 2007
1EFE
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AN ACTIVE MINI-PROINSULIN, M2PI
Descriptor:MINI-PROINSULIN
Authors:Cho, Y., Chang, S.G., Choi, K.D., Shin, H., Ahn, B., Kim, K.S.
Deposit date:2000-02-08
Release date:2000-03-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of an Active Mini-Proinsulin, M2PI: Inter-chain Flexibility is Crucial for Insulin Activity
J.Biochem.Mol.Biol., 33, 2000
1NH7
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ATP PHOSPHORIBOSYLTRANSFERASE (ATP-PRTASE) FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:ATP Phosphoribosyltransferase, SULFATE ION, MAGNESIUM ION
Authors:Cho, Y., Sharma, V., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-12-18
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of ATP Phosphoribosyltransferase from Mycobacterium Tuberculosis
J.Biol.Chem., 278, 2003
1NH8
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ATP PHOSPHORIBOSYLTRANSFERASE (ATP-PRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AMP AND HISTIDINE
Descriptor:ATP Phosphoribosyltransferase, SULFATE ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Cho, Y., Sharma, V., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-12-18
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of ATP phosphoribosyltransferase from Mycobacterium tuberculosis
J.Biol.Chem., 278, 2003
1TSR
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P53 CORE DOMAIN IN COMPLEX WITH DNA
Descriptor:DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR), ...
Authors:Cho, Y., Gorina, S., Jeffrey, P., Pavletich, N.
Deposit date:1995-07-28
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265, 1994
1TUP
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TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA
Descriptor:DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR ), ...
Authors:Cho, Y., Gorina, S., Jeffrey, P.D., Pavletich, N.P.
Deposit date:1995-07-11
Release date:1995-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265, 1994
2E6L
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STRUCTURE OF MOUSE WRN EXONUCLEASE DOMAIN
Descriptor:Werner syndrome ATP-dependent helicase homolog, SULFATE ION, ZINC ION
Authors:Cho, Y., Choi, J.M.
Deposit date:2006-12-27
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:probing the roles of active site residues in 3'-5' exonuclease of werner syndrome protein
TO BE PUBLISHED
2E6M
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STRUCTURE OF MOUSE WERNER EXONUCLEASE DOMAIN
Descriptor:Werner syndrome ATP-dependent helicase homolog, SULFATE ION
Authors:Cho, Y., Choi, J.M.
Deposit date:2006-12-27
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:probing the roles of active site residues in 3'-5' exonuclease of werner syndrome protein
TO BE PUBLISHED
3RF4
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ANCYLOSTOMA CEYLANICUM MIF IN COMPLEX WITH FUROSEMIDE
Descriptor:Macrophage migration inhibitory factor, 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, IMIDAZOLE, ...
Authors:Cho, Y., Lolis, E.
Deposit date:2011-04-05
Release date:2011-10-12
Last modified:2012-12-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors.
Chem.Biol., 18, 2011
3RF5
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ANCYLOSTOMA CEYLANICUM MIF IN COMPLEX WITH N-(2,3,4,5,6-PENTAFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE
Descriptor:Macrophage migration inhibitory factor, 2-[(furan-2-ylmethyl)amino]benzoic acid, IMIDAZOLE, ...
Authors:Cho, Y., Lolis, E.
Deposit date:2011-04-05
Release date:2011-10-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors.
Chem.Biol., 18, 2011
2ZU6
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CRYSTAL STRUCTURE OF THE EIF4A-PDCD4 COMPLEX
Descriptor:Eukaryotic initiation factor 4A-I, Programmed cell death protein 4, 1,2-ETHANEDIOL, ...
Authors:Cho, Y., Chang, J.H., Sohn, S.Y.
Deposit date:2008-10-13
Release date:2009-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the eIF4A-PDCD4 complex
Proc.Natl.Acad.Sci.Usa, 106, 2009
2ZXX
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CRYSTAL STRUCTURE OF CDT1/GEMININ COMPLEX
Descriptor:Geminin, DNA replication factor Cdt1
Authors:Cho, Y., Lee, C., Hong, B.S., Choi, J.M.
Deposit date:2009-01-08
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Nature, 430, 2004
4R89
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CRYSTAL STRUCTURE OF PAFAN1 - 5' FLAP DNA COMPLEX WITH MANGANASE
Descriptor:Uncharacterized protein, DNA (5'-D(P*AP*CP*CP*AP*GP*AP*CP*AP*CP*AP*CP*AP*TP*TP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), ...
Authors:Cho, Y., Gwon, G.H., Kim, Y.R.
Deposit date:2014-08-30
Release date:2014-10-29
Method:X-RAY DIFFRACTION (4.002 Å)
Cite:Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1
Genes Dev., 28, 2014
4R8A
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CRYSTAL STRUCTURE OF PAFAN1 - 5' FLAP DNA COMPLEX
Descriptor:Uncharacterized protein, DNA (5'-D(P*AP*CP*CP*AP*GP*AP*CP*AP*CP*AP*CP*AP*TP*TP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), ...
Authors:Cho, Y., Gwon, G.H., Kim, Y.R.
Deposit date:2014-08-30
Release date:2014-10-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1
Genes Dev., 28, 2014
2YT4
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CRYSTAL STRUCTURE OF HUMAN DGCR8 CORE
Descriptor:Protein DGCR8
Authors:Cho, Y., Sohn, S.Y.
Deposit date:2007-04-05
Release date:2007-08-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human DGCR8 core
Nat.Struct.Mol.Biol., 14, 2007
3A4C
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CRYSTAL STRUCTURE OF CDT1 C TERMINAL DOMAIN
Descriptor:DNA replication factor Cdt1
Authors:Cho, Y., Lee, J.H.
Deposit date:2009-07-06
Release date:2009-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.889 Å)
Cite:Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors
Protein Sci., 18, 2009
3B6Q
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) MUTANT T686A IN COMPLEX WITH GLUTAMATE AT 2.0 RESOLUTION
Descriptor:Glutamate receptor 2, SULFATE ION, GLUTAMIC ACID
Authors:Cho, Y., Lolis, E., Howe, J.R.
Deposit date:2007-10-29
Release date:2008-02-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
J.Neurosci., 28, 2008
3B6T
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) T686A MUTANT IN COMPLEX WITH QUISQUALATE AT 2.1 RESOLUTION
Descriptor:Glutamate receptor 2, SULFATE ION, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID
Authors:Cho, Y., Lolis, E., Howe, J.R.
Deposit date:2007-10-29
Release date:2008-02-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
J.Neurosci., 28, 2008
3B6W
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) T686S MUTANT IN COMPLEX WITH GLUTAMATE AT 1.7 RESOLUTION
Descriptor:Glutamate receptor 2, SULFATE ION, GLUTAMIC ACID
Authors:Cho, Y., Lolis, E., Howe, J.R.
Deposit date:2007-10-29
Release date:2008-02-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
J.Neurosci., 28, 2008
3IJG
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MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) BOUND TO THE (R)-STEREOISOMER OF AV1013
Descriptor:Macrophage migration inhibitory factor, CHLORIDE ION, (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one
Authors:Crichlow, G.V., Cho, Y., Lolis, E.J.
Deposit date:2009-08-04
Release date:2010-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IJJ
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TERNARY COMPLEX OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) BOUND BOTH TO 4-HYDROXYPHENYLPYRUVATE AND TO THE ALLOSTERIC INHIBITOR AV1013 (R-STEREOISOMER)
Descriptor:Macrophage migration inhibitory factor, (2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ...
Authors:Crichlow, G.V., Cho, Y., Lolis, E.J.
Deposit date:2009-08-04
Release date:2010-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Proc.Natl.Acad.Sci.USA, 107, 2010
4WFQ
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CRYSTAL STRUCTURE OF TFIIH SUBUNIT
Descriptor:Suppressor of stem-loop protein 1, SULFATE ION, GLYCEROL
Authors:Cho, Y., Kim, J.S., Lim, H.S.
Deposit date:2014-09-17
Release date:2015-02-18
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the Rad3/XPD regulatory domain of Ssl1/p44
J.Biol.Chem., 290, 2015
5Y7G
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CRYSTAL STRUCTURE OF PAFAN1 BOUND TO 1NT 5'FLAP DNA WITH GAP
Descriptor:Fanconi-associated nuclease 1 homolog, DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), DNA (5'-D(P*GP*AP*AP*TP*GP*TP*GP*TP*GP*TP*CP*TP*CP*AP*AP*TP*CP*CP*CP*AP*AP*CP*TP*T)-3'), ...
Authors:Cho, Y., Jin, H.
Deposit date:2017-08-17
Release date:2018-03-14
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural mechanism of DNA interstrand cross-link unhooking by the bacterial FAN1 nuclease.
J. Biol. Chem., 293, 2018
1B73
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GLUTAMATE RACEMASE FROM AQUIFEX PYROPHILUS
Descriptor:GLUTAMATE RACEMASE
Authors:Hwang, K.Y., Cho, C.S., Kim, S.S., Yu, Y.G., Cho, Y.
Deposit date:1999-01-26
Release date:1999-01-28
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and mechanism of glutamate racemase from Aquifex pyrophilus.
Nat.Struct.Biol., 6, 1999
1B74
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GLUTAMATE RACEMASE FROM AQUIFEX PYROPHILUS
Descriptor:GLUTAMATE RACEMASE, D-GLUTAMINE
Authors:Hwang, K.Y., Cho, C.S., Kim, S.S., Yu, Y.G., Cho, Y.
Deposit date:1999-01-27
Release date:2000-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and mechanism of glutamate racemase from Aquifex pyrophilus.
Nat.Struct.Biol., 6, 1999