Author results

5Y7X
  • Download 5y7x
  • View 5y7x
Molmil generated image of 5y7x
HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) DELTA IN COMPLEXED WITH A POTENT AND SELECTIVE AGONIST
Descriptor:Peroxisome proliferator-activated receptor delta, 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-selenazol-5-yl]methylsulfanyl]phenoxy]ethanoic acid, POTASSIUM ION, ...
Authors:Kim, H.L., Chin, J.W., Cho, S.J., Song, J.Y., Yoon, H.S., Bae, J.H.
Deposit date:2017-08-18
Release date:2018-08-01
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Design, synthesis, and the X-ray co-crystal structure of Highly Potent, Selective, and Orally Bioavailable, Novel Peroxisome Proliferator-Activated Receptor delta Agonists
To Be Published
2X25
  • Download 2x25
  • View 2x25
Molmil generated image of 2x25
FREE ACETYL-CYPA ORTHORHOMBIC FORM
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Lammers, M., Neumann, H., Chin, J.W., James, L.C.
Deposit date:2010-01-11
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerization.
Nat.Chem.Biol., 6, 2010
2X2A
  • Download 2x2a
  • View 2x2a
Molmil generated image of 2x2a
FREE ACETYL-CYPA TRIGONAL FORM
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, GLYCEROL, SULFATE ION
Authors:Lammers, M., Neumann, H., Chin, J.W., James, L.C.
Deposit date:2010-01-12
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerization.
Nat.Chem.Biol., 6, 2010
2X2C
  • Download 2x2c
  • View 2x2c
Molmil generated image of 2x2c
ACETYL-CYPA:CYCLOSPORINE COMPLEX
Descriptor:CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Lammers, M., Neumann, H., Chin, J.W., James, L.C.
Deposit date:2010-01-12
Release date:2010-03-23
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerisation
Nat.Chem.Biol., 6, 2010
2X2D
  • Download 2x2d
  • View 2x2d
Molmil generated image of 2x2d
ACETYL-CYPA:HIV-1 N-TERM CAPSID DOMAIN COMPLEX
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, CAPSID PROTEIN P24
Authors:Lammers, M., Neumann, H., Chin, J.W., James, L.C.
Deposit date:2010-01-12
Release date:2010-03-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerisation
Nat.Chem.Biol., 6, 2010
2XK5
  • Download 2xk5
  • View 2xk5
Molmil generated image of 2xk5
CRYSTAL STRUCTURE OF K6-LINKED DIUBIQUITIN
Descriptor:UBIQUITIN, ZINC ION
Authors:Virdee, S., Chin, J.W., Komander, D.
Deposit date:2010-07-07
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Engineered Diubiquitin Synthesis Reveals K29-Isopeptide Specificity of an Otu Deubiquitinase
Nat.Chem.Biol., 6, 2010
4H9N
  • Download 4h9n
  • View 4h9n
Molmil generated image of 4h9n
COMPLEX STRUCTURE 1 OF DAXX/H3.3(SUB5)/H4
Descriptor:Histone H3.3, Histone H4, Death domain-associated protein 6, ...
Authors:Elsasser, S.J., Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4H9O
  • Download 4h9o
  • View 4h9o
Molmil generated image of 4h9o
COMPLEX STRUCTURE 2 OF DAXX/H3.3(SUB5,G90M)/H4
Descriptor:Histone H3.3, Histone H4, Death domain-associated protein 6, ...
Authors:Elsasser, S.J., Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-10
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4H9P
  • Download 4h9p
  • View 4h9p
Molmil generated image of 4h9p
COMPLEX STRUCTURE 3 OF DAXX/H3.3(SUB5,G90A)/H4
Descriptor:Histone H3.3, Histone H4, Death domain-associated protein 6, ...
Authors:Elsasser, S.J., Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-17
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4H9Q
  • Download 4h9q
  • View 4h9q
Molmil generated image of 4h9q
COMPLEX STRUCTURE 4 OF DAXX(E225A)/H3.3(SUB5)/H4
Descriptor:Histone H3.3, Histone H4, Death domain-associated protein 6, ...
Authors:Elsasser, S.J., Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4H9R
  • Download 4h9r
  • View 4h9r
Molmil generated image of 4h9r
COMPLEX STRUCTURE 5 OF DAXX(E225A)/H3.3(SUB5,G90A)/H4
Descriptor:Histone H3.3, Histone H4, Death domain-associated protein 6, ...
Authors:Elsasser, S.J., Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-17
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4H9S
  • Download 4h9s
  • View 4h9s
Molmil generated image of 4h9s
COMPLEX STRUCTURE 6 OF DAXX/H3.3(SUB7)/H4
Descriptor:Histone H3.3, Histone H4, Death domain-associated protein 6, ...
Authors:Elsasser, S.J., Huang, H., Lewis, P.W., Chin, J.W., Allis, D.C., Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4WIP
  • Download 4wip
  • View 4wip
Molmil generated image of 4wip
DIX DOMAIN OF HUMAN DVL2
Descriptor:Segment polarity protein dishevelled homolog DVL-2, PENTAETHYLENE GLYCOL
Authors:Fiedler, M., Bienz, M., Madrzak, J., Chin, J.W.
Deposit date:2014-09-26
Release date:2015-05-13
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.
Nat Commun, 6, 2015
5FR2
  • Download 5fr2
  • View 5fr2
Molmil generated image of 5fr2
FARNESYLATED RHOA-GDP IN COMPLEX WITH RHOGDI-ALPHA, LYSINE ACETYLATED AT K178
Descriptor:TRANSFORMING PROTEIN RHOA, RHO GDP-DISSOCIATION INHIBITOR 1, FARNESYL, ...
Authors:Kuhlmann, N., Wroblowski, S., Knyphausen, P., de Boor, S., Brenig, J., Zienert, A.Y., Meyer-Teschendorf, K., Praefcke, G.J.K., Nolte, H., Krueger, M., Schacherl, M., Baumann, U., James, L.C., Chin, J.W., Lammers, M.
Deposit date:2015-12-15
Release date:2016-01-13
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation.
J.Biol.Chem., 291, 2016
5K9P
  • Download 5k9p
  • View 5k9p
Molmil generated image of 5k9p
SER20 PHOSPHORYLATED UBIQUITIN
Descriptor:Polyubiquitin-B
Authors:Huguenin-Dezot, N., Chin, J.W.
Deposit date:2016-06-01
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity.
Cell Rep, 16, 2016
5YSO
  • Download 5yso
  • View 5yso
Molmil generated image of 5yso
CRYSTAL STRUCTURE OF ESTROGEN RELATED RECEPTOR-3 (ERR-GAMMA) LIGAND BINDING DOMAIN WITH DN200434
Descriptor:Estrogen-related receptor gamma, 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol
Authors:Cho, S.J., Chin, J.W., Yoon, H.S., Jeon, Y.H., Bae, J.H., Song, J.Y.
Deposit date:2017-11-14
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:A novel orally active inverse agonist of estrogen-related receptor gamma (ERRg), DN200434, enhances sodium iodide symporter function in mice with anaplastic thyroid cancer
To Be Published
6ECD
  • Download 6ecd
  • View 6ecd
Molmil generated image of 6ecd
VLM2 THIOESTERASE DOMAIN WITH GENETICALLY ENCODED 2,3-DIAMINOPROPIONIC ACID BOUND WITH A TETRADEPSIPEPTIDE
Descriptor:Vlm2, tetradepsipeptide
Authors:Alonzo, D.A., Huguenin-Dezot, N., Heberlig, G.W., Mahesh, M., Nguyen, D.P., Dornan, M.H., Boddy, C.N., Chin, J.W., Schmeing, T.M.
Deposit date:2018-08-07
Release date:2018-12-12
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6ECE
  • Download 6ece
  • View 6ece
Molmil generated image of 6ece
VLM2 THIOESTERASE DOMAIN WITH GENETICALLY ENCODED 2,3-DIAMINOPROPIONIC ACID BOUND WITH A DODECADEPSIPEPTIDE, SPACE GROUP H3
Descriptor:Vlm2, dodecadepsipeptide
Authors:Alonzo, D.A., Huguenin-Dezot, N., Heberlig, G.W., Mahesh, M., Nguyen, D.P., Dornan, M.H., Boddy, C.N., Chin, J.W., Schmeing, T.M.
Deposit date:2018-08-07
Release date:2018-12-12
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6ECF
  • Download 6ecf
  • View 6ecf
Molmil generated image of 6ecf
VLM2 THIOESTERASE DOMAIN WITH GENETICALLY ENCODED 2,3-DIAMINOPROPIONIC ACID BOUND WITH A DODECADEPSIPEPTIDE, SPACE GROUP P1
Descriptor:Vlm2, dodecadepsipeptide
Authors:Alonzo, D.A., Huguenin-Dezot, N., Heberlig, G.W., Mahesh, M., Nguyen, D.P., Dornan, M.H., Boddy, C.N., Chin, J.W., Schmeing, T.M.
Deposit date:2018-08-07
Release date:2018-12-12
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6HRM
  • Download 6hrm
  • View 6hrm
Molmil generated image of 6hrm
E. COLI 70S D2D8 STAPLED RIBOSOME
Descriptor:stapled 16S-23S rRNA,stapled 16S-23S rRNA,stapled 16S-23S rRNA,stapled 16S-23S rRNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Schmied, W.H., Tnimov, Z., Uttamapinant, C., Rae, C.D., Fried, S.D., Chin, J.W.
Deposit date:2018-09-27
Release date:2018-12-19
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Controlling orthogonal ribosome subunit interactions enables evolution of new function.
Nature, 564, 2018
6FHK
  • Download 6fhk
  • View 6fhk
Molmil generated image of 6fhk
STRUCTURE OF A MODIFIED PROTEIN CONTAINING A GENETICALLY ENCODED PHOSPHOSERINE
Descriptor:Heat shock 70 kDa protein 1A, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ...
Authors:Mukherjee, M., Bayliss, R.
Deposit date:2018-01-14
Release date:2018-10-24
Method:X-RAY DIFFRACTION (1.657 Å)
Cite:Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release.
Sci Signal, 11, 2018
2YBG
  • Download 2ybg
  • View 2ybg
Molmil generated image of 2ybg
STRUCTURE OF LYS120-ACETYLATED P53 CORE DOMAIN
Descriptor:CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Arbely, E., Allen, M.D., Joerger, A.C., Fersht, A.R.
Deposit date:2011-03-08
Release date:2011-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Acetylation of Lysine 120 of P53 Endows DNA- Binding Specificity at Effective Physiological Salt Concentration.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PHU
  • Download 3phu
  • View 3phu
Molmil generated image of 3phu
OTU DOMAIN OF CRIMEAN CONGO HEMORRHAGIC FEVER VIRUS
Descriptor:RNA-directed RNA polymerase L, GLYCEROL
Authors:Akutsu, M., Ye, Y., Virdee, S., Komander, D.
Deposit date:2010-11-04
Release date:2011-02-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PHW
  • Download 3phw
  • View 3phw
Molmil generated image of 3phw
OTU DOMAIN OF CRIMEAN CONGO HEMORRHAGIC FEVER VIRUS IN COMPLEX WITH UBIQUITIN
Descriptor:RNA-directed RNA polymerase L, Ubiquitin-40S ribosomal protein S27a, ETHANAMINE
Authors:Akutsu, M., Ye, Y., Virdee, S., Komander, D.
Deposit date:2010-11-04
Release date:2011-02-02
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PHX
  • Download 3phx
  • View 3phx
Molmil generated image of 3phx
OTU DOMAIN OF CRIMEAN CONGO HEMORRHAGIC FEVER VIRUS IN COMPLEX WITH ISG15
Descriptor:RNA-directed RNA polymerase L, Ubiquitin-like protein ISG15, ZINC ION, ...
Authors:Akutsu, M., Ye, Y., Virdee, S., Komander, D.
Deposit date:2010-11-04
Release date:2011-02-02
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
<12>
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan