Author results

6INF
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A GLYCOSYLTRANSFERASE COMPLEX WITH UDP
Descriptor:UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE
Authors:Zhu, X., Yang, T., Naismith, J.H.
Deposit date:2018-10-25
Release date:2019-07-31
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
6ING
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A COMPLEX STRUCTURE OF H25A MUTANT OF GLYCOSYLTRANSFERASE WITH UDP
Descriptor:UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE, GLYCEROL
Authors:Zhu, X., Naismith, J.H.
Deposit date:2018-10-25
Release date:2019-07-31
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
6INH
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A GLYCOSYLTRANSFERASE WITH UDP AND THE SUBSTRATE
Descriptor:UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE, 1-O-[(8alpha,9beta,10alpha,13alpha)-13-(beta-D-glucopyranosyloxy)-18-oxokaur-16-en-18-yl]-beta-D-glucopyranose, ...
Authors:Zhu, X.
Deposit date:2018-10-25
Release date:2019-07-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
6INI
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A GLYCOSYLTRANSFERASE COMPLEX WITH UDP AND THE PRODUCT
Descriptor:UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Zhu, X., Yang, T., Naismith, J.H.
Deposit date:2018-10-25
Release date:2019-07-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
6NZT
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CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH VOXILAPREVIR
Descriptor:HCV NS3/4A protease, Voxilaprevir, ZINC ION, ...
Authors:Appleby, T.C., Taylor, J.G.
Deposit date:2019-02-14
Release date:2019-07-10
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®.
Bioorg.Med.Chem.Lett., 29, 2019
6NZV
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CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH COMPOUND 12
Descriptor:HCV NS3/4A protease, (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide, ZINC ION, ...
Authors:Appleby, T.C., Taylor, J.G.
Deposit date:2019-02-14
Release date:2019-07-10
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®.
Bioorg.Med.Chem.Lett., 29, 2019
5GZO
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
Descriptor:Genome polyprotein, Antibody heavy chain, Antibody light chain
Authors:Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2016-09-29
Release date:2017-01-18
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.755 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5H1Y
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CRYSTAL STRUCTURE OF THE DDX41 DEAD DOMAIN IN COMPLEX WITH SO42- AND MG2+
Descriptor:Probable ATP-dependent RNA helicase DDX41, SULFATE ION, MAGNESIUM ION
Authors:Jiang, Y., Ouyang, S., Liu, Z.J.
Deposit date:2016-10-13
Release date:2017-01-18
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural and functional analyses of human DDX41 DEAD domain
Protein Cell, 8, 2017
5GZN
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
Descriptor:Genome polyprotein, Antibody Heavy chain, Antibody light chain
Authors:Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2016-09-29
Release date:2016-12-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5GZR
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ZIKA VIRUS E PROTEIN COMPLEXED WITH A NEUTRALIZING ANTIBODY Z23-FAB
Descriptor:structural protein E, strutural protein M, Z23 Fab heavy chain, ...
Authors:Gao, G.G., Shi, Y., Peng, R., Liu, S.
Deposit date:2016-10-01
Release date:2016-11-30
Last modified:2016-12-28
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5D39
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TRANSCRIPTION FACTOR-DNA COMPLEX
Descriptor:Signal transducer and activator of transcription 6, DNA (5'-D(P*TP*CP*TP*GP*TP*CP*TP*TP*CP*CP*AP*GP*GP*AP*AP*AP*TP*CP*CP*AP*T)-3'), DNA (5'-D(P*AP*TP*GP*GP*AP*TP*TP*TP*CP*CP*TP*GP*GP*AP*AP*GP*AP*CP*AP*GP*A)-3')
Authors:Li, J., Niu, F., Ouyang, S., Liu, Z.
Deposit date:2015-08-06
Release date:2016-08-10
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for DNA recognition by STAT6
Proc.Natl.Acad.Sci.USA, 113, 2016
4Y5U
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TRANSCRIPTION FACTOR
Descriptor:Signal transducer and activator of transcription 6, NICKEL (II) ION
Authors:Li, J., Niu, F., Ouyang, S., Liu, Z.
Deposit date:2015-02-12
Release date:2016-02-17
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.708 Å)
Cite:Structural basis for DNA recognition by STAT6
Proc.Natl.Acad.Sci.USA, 113, 2016
4Y5W
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TRANSCRIPTION FACTOR-DNA COMPLEX
Descriptor:Signal transducer and activator of transcription 6, DNA (5'-D(P*AP*TP*GP*GP*AP*TP*TP*TP*CP*CP*TP*AP*GP*GP*AP*AP*GP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*CP*TP*TP*CP*CP*TP*AP*GP*GP*AP*AP*AP*TP*CP*CP*AP*T)-3')
Authors:Li, J., Niu, F., Ouyang, S., Liu, Z.
Deposit date:2015-02-12
Release date:2016-02-17
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (3.104 Å)
Cite:Structural basis for DNA recognition by STAT6
Proc.Natl.Acad.Sci.USA, 113, 2016
4QGU
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PROTEIN DOMAIN COMPLEX WITH SSDNA
Descriptor:Gamma-interferon-inducible protein 16, DNA (5'-D(P*AP*GP*GP*CP*CP*GP*GP*CP*GP*TP*GP*A)-3')
Authors:Ni, X., Ru, H., Zhao, L., Shaw, N., Ding, W., Songying, O., Liu, Z.-J.
Deposit date:2014-05-25
Release date:2015-06-17
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.545 Å)
Cite:New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16.
J Mol Cell Biol, 8, 2016
3J9B
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ELECTRON CRYO-MICROSCOPY OF AN RNA POLYMERASE
Descriptor:Polymerase, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ...
Authors:Chang, S.H., Sun, D.P., Liang, H.H., Wang, J., Li, J., Guo, L., Wang, X.L., Guan, C.C., Boruah, B.M., Yuan, L.M., Feng, F., Yang, M.R., Wojdyla, J., Wang, J.W., Wang, M.T., Wang, H.W., Liu, Y.F.
Deposit date:2014-12-16
Release date:2015-02-18
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution.
Mol.Cell, 2015
4NOJ
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CRYSTAL STRUCTURE OF THE MATURE FORM OF ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN ACTIVATED AT PH 3.5
Descriptor:Legumain
Authors:Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
Deposit date:2013-11-19
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOK
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CRYSTAL STRUCTURE OF PROENZYME ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN AT PH 7.5
Descriptor:Legumain
Authors:Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
Deposit date:2013-11-19
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOL
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CRYSTAL STRUCTURE OF PROENZYME ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN MUTANT D233A AT PH 7.5
Descriptor:Legumain
Authors:Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
Deposit date:2013-11-19
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4NOM
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CRYSTAL STRUCTURE OF ASPARAGINYL ENDOPEPTIDASE (AEP)/LEGUMAIN ACTIVATED AT PH 4.5
Descriptor:Legumain
Authors:Zhao, L., Hua, T., Ru, H., Ni, X., Shaw, N., Jiao, L., Ding, W., Qu, L., Ouyang, S., Liu, Z.J.
Deposit date:2013-11-19
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
4JBJ
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STRUCTURAL MIMICRY FOR FUNCTIONAL ANTAGONISM
Descriptor:Interferon-activable protein 202
Authors:Ru, H., Ni, X., Ma, F., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
Deposit date:2013-02-19
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.692 Å)
Cite:Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBK
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MOLECULAR BASIS FOR ABROGATION OF ACTIVATION OF PRO-INFLAMMATORY CYTOKINES
Descriptor:Interferon-activable protein 202, DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3')
Authors:Ru, H., Ni, X., Crowley, C., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
Deposit date:2013-02-19
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.963 Å)
Cite:Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBM
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STRUCTURE OF MURINE DNA BINDING PROTEIN BOUND WITH DS DNA
Descriptor:Interferon-inducible protein AIM2, DNA (5'-D(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3')
Authors:Ru, H., Ni, X., Crowley, C., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
Deposit date:2013-02-19
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.218 Å)
Cite:Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4J1G
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LEANYER ORTHOBUNYAVIRUS NUCLEOPROTEIN-SSRNA COMPLEX
Descriptor:Nucleocapsid, RNA (45-MER)
Authors:Niu, F., Shaw, N., Wang, Y., Jiao, L., Ding, W., Li, X., Zhu, P., Upur, H., Ouyang, S., Cheng, G., Liu, Z.J.
Deposit date:2013-02-01
Release date:2013-04-10
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J1J
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LEANYER ORTHOBUNYAVIRUS NUCLEOPROTEIN-SSDNA COMPLEX
Descriptor:Nucleocapsid, DNA (5'-D(P*AP*CP*CP*AP*AP*AP*CP*AP*AP*CP*CP*CP*AP*CP*CP*CP*A)-3')
Authors:Niu, F., Shaw, N., Wang, Y., Jiao, L., Ding, W., Li, X., Zhu, P., Upur, H., Ouyang, S., Cheng, G., Liu, Z.J.
Deposit date:2013-02-01
Release date:2013-04-10
Last modified:2014-11-05
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J0U
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CRYSTAL STRUCTURE OF IFIT5/ISG58
Descriptor:Interferon-induced protein with tetratricopeptide repeats 5
Authors:Liu, Y., Liang, H., Feng, F., Yuan, L., Wang, Y.E., Crowley, C., Lv, Z., Li, J., Zeng, S., Cheng, G.
Deposit date:2013-01-31
Release date:2013-02-13
Method:X-RAY DIFFRACTION (1.969 Å)
Cite:Crystal Structure of IFIT5
To be Published
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