Author results

1JXH
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4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE KINASE FROM SALMONELLA TYPHIMURIUM
分子名称:PHOSPHOMETHYLPYRIMIDINE KINASE, SULFATE ION
著者Cheng, G., Bennett, E.M., Begley, T.P., Ealick, S.E.
登録日2001-09-07
公開日2002-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution.
Structure, 10, 2002
1JXI
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4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE KINASE FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE
分子名称:PHOSPHOMETHYLPYRIMIDINE KINASE, SULFATE ION, 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE
著者Cheng, G., Bennett, E.M., Begley, T.P., Ealick, S.E.
登録日2001-09-07
公開日2002-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution.
Structure, 10, 2002
1KZZ
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DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3
分子名称:TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator
著者Li, C., Ni, C.-Z., Havert, M.L., Cabezas, E., He, J., Kaiser, D., Reed, J.C., Satterthwait, A.C., Cheng, G., Ely, K.R.
登録日2002-02-08
公開日2002-04-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure, 10, 2002
1L0A
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DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3
分子名称:TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator
著者Li, C., Ni, C.-Z., Havert, M.L., Cabezas, E., He, J., Kaiser, D., Reed, J.C., Satterthwait, A.C., Cheng, G., Ely, K.R.
登録日2002-02-08
公開日2002-04-10
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure, 10, 2002
1RF3
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STRUCTURALLY DISTINCT RECOGNITION MOTIFS IN LYMPHOTOXIN-B RECEPTOR AND CD40 FOR TRAF-MEDIATED SIGNALING
分子名称:TNF receptor associated factor 3, 24-residue peptide from Lymphotoxin-B Receptor
著者Li, C., Norris, P.S., Ni, C.Z., Havert, M.L., Chiong, E.M., Tran, B.R., Cabezas, E., Cheng, G., Reed, J.C., Satterthwait, A.C., Ware, C.F., Ely, K.R.
登録日2003-11-07
公開日2004-07-06
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling.
J.Biol.Chem., 278, 2003
2GKW
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KEY CONTACTS PROMOTE RECONGNITO OF BAFF-R BY TRAF3
分子名称:TNF receptor-associated factor 3, Tumor necrosis factor receptor superfamily member 13C
著者Ely, K.R.
登録日2006-04-03
公開日2006-04-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation.
J.Immunol., 173, 2004
3ANL
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CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH PYRIDIN-2-YLMETHYLPHOSPHONIC ACID
分子名称:1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (pyridin-2-ylmethyl)phosphonic acid
著者Endo, K., Kato, M., Deng, L., Song, Y., Yajima, S.
登録日2010-09-03
公開日2011-02-23
最終更新日2011-10-19
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes
ACS Med Chem Lett, 2, 2011
3ANM
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CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH 5-PHENYLPYRIDIN-2-YLMETHYLPHOSPHONIC ACID
分子名称:1-deoxy-D-xylulose 5-phosphate reductoisomerase, [(5-phenylpyridin-2-yl)methyl]phosphonic acid, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Endo, K., Kato, M., Deng, L., Song, Y., Yajima, S.
登録日2010-09-03
公開日2011-02-23
最終更新日2011-10-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes
ACS Med Chem Lett, 2, 2011
3ANN
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CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH QUINOLIN-2-YLMETHYLPHOSPHONIC ACID
分子名称:1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (quinolin-2-ylmethyl)phosphonic acid
著者Endo, K., Kato, M., Deng, L., Song, Y., Yajima, S.
登録日2010-09-03
公開日2011-02-23
最終更新日2011-10-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes
ACS Med Chem Lett, 2, 2011
3J9B
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ELECTRON CRYO-MICROSCOPY OF AN RNA POLYMERASE
分子名称:Polymerase, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ...
著者Chang, S.H., Sun, D.P., Liang, H.H., Wang, J., Li, J., Guo, L., Wang, X.L., Guan, C.C., Boruah, B.M., Yuan, L.M., Feng, F., Yang, M.R., Wojdyla, J., Wang, J.W., Wang, M.T., Wang, H.W., Liu, Y.F.
登録日2014-12-16
公開日2015-02-18
最終更新日2019-10-09
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution.
Mol.Cell, 2015
3M06
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CRYSTAL STRUCTURE OF TRAF2
分子名称:TNF receptor-associated factor 2
著者Kabaleeswaran, V., Wu, H.
登録日2010-03-02
公開日2010-04-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Mol.Cell, 38, 2010
3M0A
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CRYSTAL STRUCTURE OF TRAF2:CIAP2 COMPLEX
分子名称:TNF receptor-associated factor 2, Baculoviral IAP repeat-containing protein 3, ZINC ION
著者Kabaleeswaran, V., Wu, H.
登録日2010-03-02
公開日2010-04-28
最終更新日2015-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Mol.Cell, 38, 2010
3M0D
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CRYSTAL STRUCTURE OF THE TRAF1:TRAF2:CIAP2 COMPLEX
分子名称:TNF receptor-associated factor 2, TNF receptor-associated factor 1, Baculoviral IAP repeat-containing protein 3, ...
著者Kabaleeswaran, V., Wu, H.
登録日2010-03-02
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Mol.Cell, 38, 2010
3RAS
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CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH A LIPOPHILIC PHOSPHONATE INHIBITOR
分子名称:1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(N-HYDROXYACETAMIDO)-1-(3,4-DICHLOROPHENYL)PROPYLPHOSPHONIC ACID, ...
著者Diao, J., Deng, L., Prasad, B.V.V., Song, Y.
登録日2011-03-28
公開日2011-05-25
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies.
J.Med.Chem., 54, 2011
3SR4
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CRYSTAL STRUCTURE OF HUMAN DOT1L IN COMPLEX WITH A SELECTIVE INHIBITOR
分子名称:Histone-lysine N-methyltransferase, H3 lysine-79 specific, (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, ...
著者Diao, J., Chen, P., Yao, Y., Prasad, B.V.V., Song, Y.
登録日2011-07-06
公開日2011-10-05
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies.
J.Am.Chem.Soc., 133, 2011
4EF4
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CRYSTAL STRUCTURE OF STING CTD COMPLEX WITH C-DI-GMP
分子名称:Transmembrane protein 173, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION
著者Ouyang, S., Ru, H., Shaw, N., Jiang, Y., Niu, F., Zhu, Y., Qiu, W., Li, Y., Liu, Z.-J.
登録日2012-03-29
公開日2012-05-16
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4EF5
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CRYSTAL STRUCTURE OF STING CTD
分子名称:Transmembrane protein 173
著者Ouyang, S., Ru, H., Shaw, N., Jiang, Y., Niu, F., Zhu, Y., Qiu, W., Li, Y., Liu, Z.-J.
登録日2012-03-29
公開日2012-05-16
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4EFO
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CRYSTAL STRUCTURE OF THE UBIQUITIN-LIKE DOMAIN OF HUMAN TBK1
分子名称:Serine/threonine-protein kinase TBK1
著者Li, J., Li, J., Miyahira, A., Sun, J., Liu, Y., Cheng, G., Liang, H.
登録日2012-03-30
公開日2012-06-27
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献Crystal structure of the ubiquitin-like domain of human TBK1.
Protein Cell, 3, 2012
4GHU
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CRYSTAL STRUCTURE OF TRAF3/CARDIF
分子名称:TNF receptor-associated factor 3, Mitochondrial antiviral-signaling protein
著者Zhang, P.
登録日2012-08-08
公開日2012-11-28
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
4GJH
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CRYSTAL STRUCTURE OF THE TRAF DOMAIN OF TRAF5
分子名称:TNF receptor-associated factor 5
著者Zhang, P., Reichardt, A., Liang, H., Wang, Y., Cheng, D., Aliyari, R., Cheng, G., Liu, Y.
登録日2012-08-09
公開日2012-11-28
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
4J0U
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CRYSTAL STRUCTURE OF IFIT5/ISG58
分子名称:Interferon-induced protein with tetratricopeptide repeats 5
著者Liu, Y., Liang, H., Feng, F., Yuan, L., Wang, Y.E., Crowley, C., Lv, Z., Li, J., Zeng, S., Cheng, G.
登録日2013-01-31
公開日2013-02-13
実験手法X-RAY DIFFRACTION (1.969 Å)
主引用文献Crystal Structure of IFIT5
To be Published
4J1G
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LEANYER ORTHOBUNYAVIRUS NUCLEOPROTEIN-SSRNA COMPLEX
分子名称:Nucleocapsid, RNA (45-MER)
著者Niu, F., Shaw, N., Wang, Y., Jiao, L., Ding, W., Li, X., Zhu, P., Upur, H., Ouyang, S., Cheng, G., Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2013-06-12
実験手法X-RAY DIFFRACTION (2.789 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J1J
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LEANYER ORTHOBUNYAVIRUS NUCLEOPROTEIN-SSDNA COMPLEX
分子名称:Nucleocapsid, DNA (5'-D(P*AP*CP*CP*AP*AP*AP*CP*AP*AP*CP*CP*CP*AP*CP*CP*CP*A)-3')
著者Niu, F., Shaw, N., Wang, Y., Jiao, L., Ding, W., Li, X., Zhu, P., Upur, H., Ouyang, S., Cheng, G., Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2014-11-05
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JBJ
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STRUCTURAL MIMICRY FOR FUNCTIONAL ANTAGONISM
分子名称:Interferon-activable protein 202
著者Ru, H., Ni, X., Ma, F., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.692 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBK
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MOLECULAR BASIS FOR ABROGATION OF ACTIVATION OF PRO-INFLAMMATORY CYTOKINES
分子名称:Interferon-activable protein 202, DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3')
著者Ru, H., Ni, X., Crowley, C., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.963 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
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