Author results

1JXH
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4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE KINASE FROM SALMONELLA TYPHIMURIUM
分子名称:PHOSPHOMETHYLPYRIMIDINE KINASE, SULFATE ION
著者Cheng, G., Bennett, E.M., Begley, T.P., Ealick, S.E.
登録日2001-09-07
公開日2002-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution.
Structure, 10, 2002
1JXI
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4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE KINASE FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE
分子名称:PHOSPHOMETHYLPYRIMIDINE KINASE, SULFATE ION, 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE
著者Cheng, G., Bennett, E.M., Begley, T.P., Ealick, S.E.
登録日2001-09-07
公開日2002-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution.
Structure, 10, 2002
4GJH
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CRYSTAL STRUCTURE OF THE TRAF DOMAIN OF TRAF5
分子名称:TNF receptor-associated factor 5
著者Zhang, P., Reichardt, A., Liang, H., Wang, Y., Cheng, D., Aliyari, R., Cheng, G., Liu, Y.
登録日2012-08-09
公開日2012-11-28
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
5GZN
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
分子名称:Genome polyprotein, Antibody Heavy chain, Antibody light chain
著者Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
登録日2016-09-29
公開日2016-12-28
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5GZO
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
分子名称:Genome polyprotein, Antibody heavy chain, Antibody light chain
著者Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
登録日2016-09-29
公開日2017-01-18
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (2.755 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
1KZZ
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DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3
分子名称:TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator
著者Li, C., Ni, C.-Z., Havert, M.L., Cabezas, E., He, J., Kaiser, D., Reed, J.C., Satterthwait, A.C., Cheng, G., Ely, K.R.
登録日2002-02-08
公開日2002-04-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure, 10, 2002
1L0A
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DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3
分子名称:TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator
著者Li, C., Ni, C.-Z., Havert, M.L., Cabezas, E., He, J., Kaiser, D., Reed, J.C., Satterthwait, A.C., Cheng, G., Ely, K.R.
登録日2002-02-08
公開日2002-04-10
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure, 10, 2002
4EFO
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CRYSTAL STRUCTURE OF THE UBIQUITIN-LIKE DOMAIN OF HUMAN TBK1
分子名称:Serine/threonine-protein kinase TBK1
著者Li, J., Li, J., Miyahira, A., Sun, J., Liu, Y., Cheng, G., Liang, H.
登録日2012-03-30
公開日2012-06-27
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献Crystal structure of the ubiquitin-like domain of human TBK1.
Protein Cell, 3, 2012
4J0U
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CRYSTAL STRUCTURE OF IFIT5/ISG58
分子名称:Interferon-induced protein with tetratricopeptide repeats 5
著者Liu, Y., Liang, H., Feng, F., Yuan, L., Wang, Y.E., Crowley, C., Lv, Z., Li, J., Zeng, S., Cheng, G.
登録日2013-01-31
公開日2013-02-13
実験手法X-RAY DIFFRACTION (1.969 Å)
主引用文献Crystal Structure of IFIT5
To be Published
4J1G
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LEANYER ORTHOBUNYAVIRUS NUCLEOPROTEIN-SSRNA COMPLEX
分子名称:Nucleocapsid, RNA (45-MER)
著者Niu, F., Shaw, N., Wang, Y., Jiao, L., Ding, W., Li, X., Zhu, P., Upur, H., Ouyang, S., Cheng, G., Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2013-06-12
実験手法X-RAY DIFFRACTION (2.789 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J1J
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LEANYER ORTHOBUNYAVIRUS NUCLEOPROTEIN-SSDNA COMPLEX
分子名称:Nucleocapsid, DNA (5'-D(P*AP*CP*CP*AP*AP*AP*CP*AP*AP*CP*CP*CP*AP*CP*CP*CP*A)-3')
著者Niu, F., Shaw, N., Wang, Y., Jiao, L., Ding, W., Li, X., Zhu, P., Upur, H., Ouyang, S., Cheng, G., Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2014-11-05
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JBJ
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STRUCTURAL MIMICRY FOR FUNCTIONAL ANTAGONISM
分子名称:Interferon-activable protein 202
著者Ru, H., Ni, X., Ma, F., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.692 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBK
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MOLECULAR BASIS FOR ABROGATION OF ACTIVATION OF PRO-INFLAMMATORY CYTOKINES
分子名称:Interferon-activable protein 202, DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3')
著者Ru, H., Ni, X., Crowley, C., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.963 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBM
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STRUCTURE OF MURINE DNA BINDING PROTEIN BOUND WITH DS DNA
分子名称:Interferon-inducible protein AIM2, DNA (5'-D(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3')
著者Ru, H., Ni, X., Crowley, C., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
登録日2013-02-19
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.218 Å)
主引用文献Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4GHU
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CRYSTAL STRUCTURE OF TRAF3/CARDIF
分子名称:TNF receptor-associated factor 3, Mitochondrial antiviral-signaling protein
著者Zhang, P.
登録日2012-08-08
公開日2012-11-28
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
6INF
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A GLYCOSYLTRANSFERASE COMPLEX WITH UDP
分子名称:UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE
著者Zhu, X., Yang, T., Naismith, J.H.
登録日2018-10-25
公開日2019-07-31
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
6ING
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A COMPLEX STRUCTURE OF H25A MUTANT OF GLYCOSYLTRANSFERASE WITH UDP
分子名称:UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE, GLYCEROL
著者Zhu, X., Naismith, J.H.
登録日2018-10-25
公開日2019-07-31
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
6INH
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A GLYCOSYLTRANSFERASE WITH UDP AND THE SUBSTRATE
分子名称:UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE, 1-O-[(8alpha,9beta,10alpha,13alpha)-13-(beta-D-glucopyranosyloxy)-18-oxokaur-16-en-18-yl]-beta-D-glucopyranose, ...
著者Zhu, X.
登録日2018-10-25
公開日2019-07-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
6INI
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A GLYCOSYLTRANSFERASE COMPLEX WITH UDP AND THE PRODUCT
分子名称:UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE, GLYCEROL, ...
著者Zhu, X., Yang, T., Naismith, J.H.
登録日2018-10-25
公開日2019-07-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
6NZV
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CRYSTAL STRUCTURE OF HCV NS3/4A PROTEASE IN COMPLEX WITH COMPOUND 12
分子名称:HCV NS3/4A protease, (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide, ZINC ION, ...
著者Appleby, T.C., Taylor, J.G.
登録日2019-02-14
公開日2019-07-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®.
Bioorg.Med.Chem.Lett., 2019
5GZR
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ZIKA VIRUS E PROTEIN COMPLEXED WITH A NEUTRALIZING ANTIBODY Z23-FAB
分子名称:structural protein E, strutural protein M, Z23 Fab heavy chain, ...
著者Gao, G.G., Shi, Y., Peng, R., Liu, S.
登録日2016-10-01
公開日2016-11-30
最終更新日2016-12-28
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
2GKW
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KEY CONTACTS PROMOTE RECONGNITO OF BAFF-R BY TRAF3
分子名称:TNF receptor-associated factor 3, Tumor necrosis factor receptor superfamily member 13C
著者Ely, K.R.
登録日2006-04-03
公開日2006-04-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation.
J.Immunol., 173, 2004
1RF3
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STRUCTURALLY DISTINCT RECOGNITION MOTIFS IN LYMPHOTOXIN-B RECEPTOR AND CD40 FOR TRAF-MEDIATED SIGNALING
分子名称:TNF receptor associated factor 3, 24-residue peptide from Lymphotoxin-B Receptor
著者Li, C., Norris, P.S., Ni, C.Z., Havert, M.L., Chiong, E.M., Tran, B.R., Cabezas, E., Cheng, G., Reed, J.C., Satterthwait, A.C., Ware, C.F., Ely, K.R.
登録日2003-11-07
公開日2004-07-06
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling.
J.Biol.Chem., 278, 2003
3ANL
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CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH PYRIDIN-2-YLMETHYLPHOSPHONIC ACID
分子名称:1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (pyridin-2-ylmethyl)phosphonic acid
著者Endo, K., Kato, M., Deng, L., Song, Y., Yajima, S.
登録日2010-09-03
公開日2011-02-23
最終更新日2011-10-19
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes
ACS Med Chem Lett, 2, 2011
3ANM
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CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH 5-PHENYLPYRIDIN-2-YLMETHYLPHOSPHONIC ACID
分子名称:1-deoxy-D-xylulose 5-phosphate reductoisomerase, [(5-phenylpyridin-2-yl)methyl]phosphonic acid, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Endo, K., Kato, M., Deng, L., Song, Y., Yajima, S.
登録日2010-09-03
公開日2011-02-23
最終更新日2011-10-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes
ACS Med Chem Lett, 2, 2011
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