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1N87
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BU of 1n87 by Molmil
Solution structure of the U-box of Prp19
Descriptor: Pre-mRNA splicing factor PRP19
Authors:Chazin, W.J, Ohi, M.D, Vander Kooi, C.W.
Deposit date:2002-11-19
Release date:2003-04-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural insights into the U-box, a domain associated with multi-ubiquitination
Nat.Struct.Biol., 10, 2003
1D1O
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BU of 1d1o by Molmil
COOPERATIVITY IN EF-HAND CA2+-BINDING PROTEINS: EVIDENCE OF SITE-SITE COMMUNICATION FROM BINDING-INDUCED CHANGES IN STRUCTURE AND DYNAMICS OF N56A CALBINDIN D9K
Descriptor: CALBINDIN D9K
Authors:Maler, L, Blankenship, J, Rance, M, Chazin, W.J.
Deposit date:1999-09-20
Release date:2000-03-08
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Site-site communication in the EF-hand Ca2+-binding protein calbindin D9k.
Nat.Struct.Biol., 7, 2000
1CDN
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BU of 1cdn by Molmil
Solution structure of (CD2+)1-calbindin D9K reveals details of the stepwise structural changes along the apo--> (CA2+)II1--> (CA2+)I,II2 binding pathway
Descriptor: CALBINDIN D9K
Authors:Akke, M, Forsen, S, Chazin, W.J.
Deposit date:1995-08-04
Release date:1995-11-14
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Solution structure of (Cd2+)1-calbindin D9k reveals details of the stepwise structural changes along the Apo-->(Ca2+)II1-->(Ca2+)I,II2 binding pathway.
J.Mol.Biol., 252, 1995
1CLB
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BU of 1clb by Molmil
Determination of the solution structure of apo calbindin D9K by nmr spectroscopy
Descriptor: CALBINDIN D9K
Authors:Skelton, N.J, Chazin, W.J.
Deposit date:1995-02-08
Release date:1995-04-20
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Determination of the solution structure of Apo calbindin D9k by NMR spectroscopy.
J.Mol.Biol., 249, 1995
1A03
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BU of 1a03 by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF CA2+-BOUND CALCYCLIN: IMPLICATIONS FOR CA2+-SIGNAL TRANSDUCTION BY S100 PROTEINS, NMR, 20 STRUCTURES
Descriptor: CALCYCLIN (RABBIT, CA2+)
Authors:Sastry, M, Ketchem, R.R, Crescenzi, O, Weber, C, Lubienski, M.J, Hidaka, H, Chazin, W.J.
Deposit date:1997-12-08
Release date:1999-03-02
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The three-dimensional structure of Ca(2+)-bound calcyclin: implications for Ca(2+)-signal transduction by S100 proteins.
Structure, 6, 1998
1B1G
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BU of 1b1g by Molmil
SOLVATED REFINEMENT OF CA-LOADED CALBINDIN D9K
Descriptor: CALCIUM ION, PROTEIN (CALBINDIN D9K)
Authors:Kordel, J, Pearlman, D.A, Chazin, W.J.
Deposit date:1998-11-20
Release date:1998-11-25
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Protein solution structure calculations in solution: solvated molecular dynamics refinement of calbindin D9k.
J.Biomol.NMR, 10, 1997
5I7M
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BU of 5i7m by Molmil
Crystal structure of Y345F mutant of human primase p58 iron-sulfur cluster domain
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION
Authors:Salay, L.E, Thompson, M.K, Chazin, W.J.
Deposit date:2016-02-17
Release date:2017-03-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355, 2017
4R4C
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BU of 4r4c by Molmil
Structure of RPA70N in complex with 5-(4-((4-(5-carboxyfuran-2-yl)-2-chlorobenzamido)methyl)phenyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid
Descriptor: 5-[4-({[4-(5-carboxyfuran-2-yl)-2-chlorobenzoyl]amino}methyl)phenyl]-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid, Replication protein A 70 kDa DNA-binding subunit
Authors:Feldkamp, M.D, Waterson, A.G, Kennedy, J.P, Patrone, J.D, Pelz, N.F, Frank, A.O, Vangamudi, B, Sousa-Fagundes, E.M, Rossanese, O.W, Fesik, S.W, Chazin, W.J.
Deposit date:2014-08-19
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Diphenylpyrazoles as replication protein a inhibitors.
ACS Med Chem Lett, 6, 2015
2CNP
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BU of 2cnp by Molmil
HIGH RESOLUTION SOLUTION STRUCTURE OF APO RABBIT CALCYCLIN, NMR, 22 STRUCTURES
Descriptor: CALCYCLIN
Authors:Maler, L, Potts, B.C.M, Chazin, W.J.
Deposit date:1999-01-07
Release date:1999-07-22
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:High resolution solution structure of apo calcyclin and structural variations in the S100 family of calcium-binding proteins.
J.Biomol.NMR, 13, 1999
1Z1D
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BU of 1z1d by Molmil
Structural Model for the interaction between RPA32 C-terminal domain and SV40 T antigen origin binding domain.
Descriptor: Large T antigen, Replication protein A 32 kDa subunit
Authors:Arunkumar, A.I, Klimovich, V, Jiang, X, Ott, R.D, Mizoue, L, Fanning, E, Chazin, W.J.
Deposit date:2005-03-03
Release date:2005-05-17
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome.
Nat.Struct.Mol.Biol., 12, 2005
1CNP
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BU of 1cnp by Molmil
THE STRUCTURE OF CALCYCLIN REVEALS A NOVEL HOMODIMERIC FOLD FOR S100 CA2+-BINDING PROTEINS, NMR, 22 STRUCTURES
Descriptor: CALCYCLIN (RABBIT, APO)
Authors:Potts, B.C.M, Smith, J, Akke, M, Macke, T.J, Okazaki, K, Hidaka, H, Case, D.A, Chazin, W.J.
Deposit date:1995-08-31
Release date:1996-10-14
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The structure of calcyclin reveals a novel homodimeric fold for S100 Ca(2+)-binding proteins.
Nat.Struct.Biol., 2, 1995
5DBR
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BU of 5dbr by Molmil
Ca2+ CaM with human cardiac Na+ channel (NaV1.5) inactivation gate
Descriptor: CALCIUM ION, Calmodulin, Sodium channel protein type 5 subunit alpha
Authors:Johnson, C.N, Thompson, M.K, Chazin, W.J.
Deposit date:2015-08-21
Release date:2017-02-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Enhanced Understanding of Ca2+ Modulation of the Human Cardiac Sodium Channel: Tight Binding of Calmodulin to the Inactivation Gate
To Be Published
6DI2
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BU of 6di2 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y397L mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-05-22
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DTZ
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BU of 6dtz by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain, Y397F mutant
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, ...
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-06-18
Release date:2018-12-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1JWD
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BU of 1jwd by Molmil
Ca2+-induced Structural Changes in Calcyclin: High-resolution Solution Structure of Ca2+-bound Calcyclin.
Descriptor: Calcyclin
Authors:Maler, L, Sastry, M, Chazin, W.J.
Deposit date:2001-09-04
Release date:2002-03-27
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:A structural basis for S100 protein specificity derived from comparative analysis of apo and Ca(2+)-calcyclin
J.Mol.Biol., 317, 2002
7TL4
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BU of 7tl4 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 6YF
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Blee, A.M, Salay, L.E, Chazin, W.J.
Deposit date:2022-01-18
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
7TL3
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BU of 7tl3 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF431
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Blee, A.M, Salay, L.E, Chazin, W.J.
Deposit date:2022-01-18
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.066 Å)
Cite:Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
7TL2
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BU of 7tl2 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF412
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ...
Authors:Blee, A.M, Salay, L.E, Chazin, W.J.
Deposit date:2022-01-18
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.529 Å)
Cite:Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
2BCB
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BU of 2bcb by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K
Descriptor: CALBINDIN D9K
Authors:Kordel, J, Skelton, N.J, Akke, M, Chazin, W.J.
Deposit date:1993-08-18
Release date:1993-10-31
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:High-resolution structure of calcium-loaded calbindin D9k.
J.Mol.Biol., 231, 1993
2BCA
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BU of 2bca by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K
Descriptor: CALBINDIN D9K
Authors:Kordel, J, Skelton, N.J, Akke, M, Chazin, W.J.
Deposit date:1993-08-18
Release date:1993-10-31
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:High-resolution structure of calcium-loaded calbindin D9k.
J.Mol.Biol., 231, 1993
9PCY
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BU of 9pcy by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF REDUCED FRENCH BEAN PLASTOCYANIN AND COMPARISON WITH THE CRYSTAL STRUCTURE OF POPLAR PLASTOCYANIN
Descriptor: COPPER (II) ION, PLASTOCYANIN
Authors:Moore, J.M, Lepre, C.A, Gippert, G.P, Chazin, W.J, Case, D.A, Wright, P.E.
Deposit date:1991-03-18
Release date:1993-10-31
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:High-resolution solution structure of reduced French bean plastocyanin and comparison with the crystal structure of poplar plastocyanin.
J.Mol.Biol., 221, 1991
5E7N
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BU of 5e7n by Molmil
Crystal Structure of RPA70N in complex with VU0085636
Descriptor: 2-({3-[(4-bromophenyl)sulfamoyl]-4-methylbenzoyl}amino)benzoic acid, Replication protein A 70 kDa DNA-binding subunit
Authors:Gilston, B.A, Patrone, J.D, Pelz, N.F, Bates, B.S, Souza-Fagundes, E.M, Vangamudi, B, Camper, D, Kuznetsov, A, Browning, C.F, Feldkamp, M.D, Olejniczak, E.T, Rossanese, O.W, Waterson, A.G, Fesik, S.W, Chazin, W.J.
Deposit date:2015-10-12
Release date:2016-01-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A.
Chemmedchem, 11, 2016
5DQO
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BU of 5dqo by Molmil
Crystal structure of Y347F mutant of human primase p58 iron-sulfur cluster domain
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Thompson, M.K, Chazin, W.J.
Deposit date:2015-09-15
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355, 2017
1CB1
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BU of 1cb1 by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF CA2+-LOADED PORCINE CALBINDIN D9K DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: CALBINDIN D9K
Authors:Akke, M, Drakenberg, T, Chazin, W.J.
Deposit date:1991-12-13
Release date:1993-10-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of Ca(2+)-loaded porcine calbindin D9k determined by nuclear magnetic resonance spectroscopy.
Biochemistry, 31, 1992
1YSM
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BU of 1ysm by Molmil
NMR Structure of N-terminal domain (Residues 1-77) of Siah-Interacting Protein.
Descriptor: Calcyclin-binding protein
Authors:Bhattacharya, S, Lee, Y.T, Michowski, W, Jastrzebska, B, Filipek, A, Kuznicki, J, Chazin, W.J.
Deposit date:2005-02-08
Release date:2005-07-26
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:The Modular Structure of SIP Facilitates Its Role in Stabilizing Multiprotein Assemblies.
Biochemistry, 44, 2005

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