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4M4C
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BU of 4m4c by Molmil
Crystal structure of Rhodostomin ARGDP mutant
Descriptor: SULFATE ION, Zinc metalloproteinase/disintegrin
Authors:Chang, Y.T, Jeng, W.Y, Shiu, J.H, Chen, C.Y, Chuang, W.J.
Deposit date:2013-08-07
Release date:2014-08-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Effect of C-terminal proline residue adjacent to the RGD motif in rhodostomin on its activity and structure
To be Published
7X4S
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BU of 7x4s by Molmil
Crystal structure of Rhodostomin ARGDMP mutant
Descriptor: Disintegrin rhodostomin
Authors:Chang, Y.T, Chuang, W.J.
Deposit date:2022-03-03
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Rhodostomin ARGDMP mutant
To be published
7X4V
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BU of 7x4v by Molmil
Crystal structure of Rhodostomin ARGDDP mutant
Descriptor: Disintegrin rhodostomin
Authors:Chang, Y.T, Chuang, W.J.
Deposit date:2022-03-03
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Crystal structure of Rhodostomin ARGDDP mutant
To be published
7X4Z
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BU of 7x4z by Molmil
Crystal structure of Rhodostomin ARGDWP mutant
Descriptor: Disintegrin rhodostomin, SULFATE ION
Authors:Chang, Y.T, Chuang, W.J.
Deposit date:2022-03-03
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structure of Rhodostomin ARGDWP mutant
To be published
7X44
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BU of 7x44 by Molmil
Crystal structure of chlorotoxin mutant - Q11N
Descriptor: Chlorotoxin
Authors:Chang, Y.T, Chuang, W.J.
Deposit date:2022-03-01
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Expression in Pichia pastoris and characterization of chlorotoxin, an anti-glioma migration agent
To Be Published
7X4D
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BU of 7x4d by Molmil
Crystal structure of chlorotoxin mutant - Y29K
Descriptor: Chlorotoxin
Authors:Chang, Y.T, Chuang, W.J.
Deposit date:2022-03-02
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Expression in Pichia pastoris and characterization of chlorotoxin, an anti-glioma migration agent
To Be Published
7X41
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BU of 7x41 by Molmil
Crystal structure of chlorotoxin, a glioma specific scorpion toxin
Descriptor: Chlorotoxin
Authors:Chang, Y.T, Chuang, W.J.
Deposit date:2022-03-01
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Expression in Pichia pastoris and characterization of chlorotoxin, an anti-glioma migration agent
To Be Published
7X43
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BU of 7x43 by Molmil
Crystal structure of chlorotoxin mutant - M1R
Descriptor: Chlorotoxin
Authors:Chang, Y.T, Chuang, W.J.
Deposit date:2022-03-01
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Expression in Pichia pastoris and characterization of chlorotoxin, an anti-glioma migration agent
To Be Published
7YPL
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BU of 7ypl by Molmil
Crystal structure of fibronectin type III domain variant, a VEGFR2-specific antagonist
Descriptor: Fibronectin, SULFATE ION
Authors:Chang, Y.T, Chen, C.Y, Chuang, W.J.
Deposit date:2022-08-03
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:A Novel Disulfide Bond Engineering of Fibronectin Type III Domain Enhances Thermostability and Solubility of VEGFR2-Specific Antagonist
To Be Published
6LSQ
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BU of 6lsq by Molmil
Crystal structure of Echistatin, an RGD-containing short disintegrin
Descriptor: Disintegrin, SULFATE ION
Authors:Chang, Y.T, Chen, Y.C, Chuang, W.J.
Deposit date:2020-01-19
Release date:2020-11-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insight into Integrin Recognition and Anticancer Activity of Echistatin.
Toxins, 12, 2020
4R5U
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BU of 4r5u by Molmil
Crystal structure of Rhodostomin R46E mutant
Descriptor: Disintegrin rhodostomin
Authors:Huang, C.H, Shiu, J.H, Chang, Y.T, Jeng, W.Y, Chuang, W.J.
Deposit date:2014-08-22
Release date:2015-08-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Effects of the regions adjacent to the RGD motif in disintegrins on their inhibitory activities and structures
To be Published
4R5R
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BU of 4r5r by Molmil
Crystal structure of Rhodostomin KKKRT mutant
Descriptor: Disintegrin rhodostomin
Authors:Huang, C.H, Shiu, J.H, Chang, Y.T, Jeng, W.Y, Chuang, W.J.
Deposit date:2014-08-21
Release date:2015-08-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:Effects of the regions adjacent to the RGD motif in disintegrins on their inhibitory activities and structures
To be Published
4RQG
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BU of 4rqg by Molmil
Crystal structure of Rhodostomin
Descriptor: Disintegrin rhodostomin
Authors:Shiu, J.H, Huang, C.H, Chang, Y.T, Jeng, W.Y, Chuang, W.J.
Deposit date:2014-11-03
Release date:2015-11-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Effects of the regions adjacent to the RGD motif in disintegrins on their inhibitory activities and structures
To be Published
3UCI
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BU of 3uci by Molmil
Crystal structure of Rhodostomin ARLDDL mutant
Descriptor: disintegrin
Authors:Shiu, J.H, Chen, C.Y, Chen, Y.C, Chang, Y.T, Chang, Y.S, Huang, C.H, Chuang, W.J.
Deposit date:2011-10-27
Release date:2012-11-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Design of Integrin AlphaVbeta3-Specific Disintegrin for Cancer Therapy
To be Published
6XGY
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BU of 6xgy by Molmil
Crystal structure of E. coli MlaFB ABC transport subunits in the dimeric state
Descriptor: ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Chang, Y, Bhabha, G, Ekiert, D.C.
Deposit date:2020-06-18
Release date:2020-07-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation.
Elife, 9, 2020
6XGZ
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BU of 6xgz by Molmil
Crystal structure of E. coli MlaFB ABC transport subunits in the monomeric state
Descriptor: 1,2-ETHANEDIOL, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ...
Authors:Chang, Y, Bhabha, G, Ekiert, D.C.
Deposit date:2020-06-18
Release date:2020-07-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation.
Elife, 9, 2020
7UDL
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BU of 7udl by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 bound to PLPx6 peptide
Descriptor: 1,2-ETHANEDIOL, 6xPLP Peptide, Designed helical repeat protein (DHR) RPB_PLP1_R6
Authors:Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDO
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BU of 7udo by Molmil
Crystal structure of designed helical repeat protein RPB_LRP2_R4 (proteolysis fragment?), forming pseudopolymeric filaments
Descriptor: 1,2-ETHANEDIOL, Designed helical repeat protein (DHR) RPB_LRP2_R4, PHOSPHATE ION
Authors:Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDJ
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BU of 7udj by Molmil
Crystal structure of designed helical repeat protein RPB_PEW3_R4 bound to PAWx4 peptide
Descriptor: 4xPAW peptide, De novo designed helical repeat protein RPB_PEW3_R4
Authors:Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDK
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BU of 7udk by Molmil
Crystal structure of designed helical repeat protein RPB_LRP2_R4 bound to LRPx4 peptide
Descriptor: 4xLRP, Designed helical repeat protein (DHR) RPB_LRP2_R4
Authors:Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDM
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BU of 7udm by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 1 (with peptide)
Descriptor: 6xPLP, Designed helical repeat protein (DHR) RPB_PLP1_R6
Authors:Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDN
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BU of 7udn by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 2
Descriptor: Designed helical repeat protein (DHR) RPB_PLP1_R6
Authors:Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UE2
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BU of 7ue2 by Molmil
Crystal structure of designed helical repeat protein RPB_PLP3_R6 bound to PLPx6 peptide
Descriptor: PLPx6 peptide, RPB_PLP3_R6
Authors:Chang, Y, Ekiert, D.C, Bhabha, G.
Deposit date:2022-03-21
Release date:2023-03-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UPO
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BU of 7upo by Molmil
Crystal structure of designed heterotrimeric assembly DHT03
Descriptor: DHT03 protein A, DHT03 protein B, DHT03 protein C
Authors:Chang, Y, Bhabha, G, Ekiert, D.C.
Deposit date:2022-04-16
Release date:2022-12-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:De novo design of obligate ABC-type heterotrimeric proteins.
Nat.Struct.Mol.Biol., 29, 2022
7UPP
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BU of 7upp by Molmil
Crystal structure of designed heterotrimeric assembly DHT03_2arm_A21/B21/C long
Descriptor: DHT03 protein A, DHT03 protein B, DHT03 protein C
Authors:Chang, Y, Bhabha, G, Ekiert, D.C.
Deposit date:2022-04-16
Release date:2022-12-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:De novo design of obligate ABC-type heterotrimeric proteins.
Nat.Struct.Mol.Biol., 29, 2022

 

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