Author results

1LBG
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LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY
Descriptor:DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), PROTEIN (LACTOSE OPERON REPRESSOR)
Authors:Lewis, M., Chang, G., Horton, N.C., Kercher, M.A., Pace, H.C., Lu, P.
Deposit date:1996-01-03
Release date:1996-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
1LBH
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INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG
Descriptor:INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG, ISOPROPYL-1-BETA-D-THIOGALACTOSIDE
Authors:Lewis, M., Chang, G., Horton, N.C., Kercher, M.A., Pace, H.C., Lu, P.
Deposit date:1996-02-17
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
1LBI
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LAC REPRESSOR
Descriptor:LAC REPRESSOR
Authors:Lewis, M., Chang, G., Horton, N.C., Kercher, M.A., Pace, H.C., Lu, P.
Deposit date:1996-02-17
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
1EFA
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CRYSTAL STRUCTURE OF THE LAC REPRESSOR DIMER BOUND TO OPERATOR AND THE ANTI-INDUCER ONPF
Descriptor:DNA (5'-D(*GP*AP*AP*T*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), LAC REPRESSOR, ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE
Authors:Bell, C.E., Lewis, M.
Deposit date:2000-02-07
Release date:2000-03-06
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A closer view of the conformation of the Lac repressor bound to operator.
Nat.Struct.Biol., 7, 2000
2GFP
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STRUCTURE OF THE MULTIDRUG TRANSPORTER EMRD FROM ESCHERICHIA COLI
Descriptor:Multidrug resistance protein D
Authors:Yin, Y., He, X., Szewczyk, P., Nguyen, T., Chang, G.
Deposit date:2006-03-22
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the multidrug transporter EmrD from Escherichia coli
Science, 312, 2006
2OAR
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MECHANOSENSITIVE CHANNEL OF LARGE CONDUCTANCE (MSCL)
Descriptor:Large-conductance mechanosensitive channel, GOLD ION
Authors:Rees, D.C., Chang, G., Spencer, R.H., Lee, A.T., Steinbacher, S., Strop, P.
Deposit date:2006-12-17
Release date:2007-01-09
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structures of the Prokaryotic Mechanosensitive Channels MscL and MscS
Current Topics in Membranes, 58, 2007
3B5D
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EMRE MULTIDRUG TRANSPORTER IN COMPLEX WITH TPP, C2 CRYSTAL FORM
Descriptor:Multidrug transporter emrE, TETRAPHENYLPHOSPHONIUM
Authors:Chang, G., Chen, Y.J.
Deposit date:2007-10-25
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:X-ray structure of EmrE supports dual topology model.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B5W
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CRYSTAL STRUCTURE OF ESCHERICIA COLI MSBA
Descriptor:Lipid A export ATP-binding/permease protein msbA
Authors:Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5.3 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B5X
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CRYSTAL STRUCTURE OF MSBA FROM VIBRIO CHOLERAE
Descriptor:Lipid A export ATP-binding/permease protein msbA
Authors:Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B5Y
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CRYSTAL STRUCTURE OF MSBA FROM SALMONELLA TYPHIMURIUM WITH AMPPNP
Descriptor:Lipid A export ATP-binding/permease protein msbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B5Z
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CRYSTAL STRUCTURE OF MSBA FROM SALMONELLA TYPHIMURIUM WITH ADP VANADATE
Descriptor:Lipid A export ATP-binding/permease protein msbA, ADENOSINE-5'-DIPHOSPHATE, VANADATE ION
Authors:Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2013-06-05
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B60
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CRYSTAL STRUCTURE OF MSBA FROM SALMONELLA TYPHIMURIUM WITH AMPPNP, HIGHER RESOLUTION FORM
Descriptor:Lipid A export ATP-binding/permease protein msbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B61
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EMRE MULTIDRUG TRANSPORTER, APO CRYSTAL FORM
Descriptor:Multidrug transporter emrE
Authors:Chang, G., Chen, Y.J.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:X-ray structure of EmrE supports dual topology model.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3B62
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EMRE MULTIDRUG TRANSPORTER IN COMPLEX WITH P4P, P21 CRYSTAL FORM
Descriptor:Multidrug transporter emrE, TETRAPHENYLPHOSPHONIUM
Authors:Chang, G., Chen, Y.J.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:X-ray structure of EmrE supports dual topology model.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3G5U
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STRUCTURE OF P-GLYCOPROTEIN REVEALS A MOLECULAR BASIS FOR POLY-SPECIFIC DRUG BINDING
Descriptor:Multidrug resistance protein 1a, MERCURY (II) ION
Authors:Aller, S.G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R., Harrell, P.M., Trinh, Y.T., Zhang, Q., Urbatsch, I.L., Chang, G.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
3G60
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STRUCTURE OF P-GLYCOPROTEIN REVEALS A MOLECULAR BASIS FOR POLY-SPECIFIC DRUG BINDING
Descriptor:Multidrug resistance protein 1a, (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
Authors:Aller, S.G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R., Harrell, P.M., Trinh, Y.T., Zhang, Q., Urbatsch, I.L., Chang, G.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
3G61
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STRUCTURE OF P-GLYCOPROTEIN REVEALS A MOLECULAR BASIS FOR POLY-SPECIFIC DRUG BINDING
Descriptor:Multidrug resistance protein 1a, (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
Authors:Aller, S.G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R., Harrell, P.M., Trinh, Y.T., Zhang, Q., Urbatsch, I.L., Chang, G.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (4.35 Å)
Cite:Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
3MKT
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STRUCTURE OF A CATION-BOUND MULTIDRUG AND TOXIN COMPOUND EXTRUSION (MATE) TRANSPORTER
Descriptor:Multi antimicrobial extrusion protein (Na(+)/drug antiporter) MATE-like MDR efflux pump
Authors:He, X., Szewczyk, P., Karyakin, A., Evin, M., Hong, W.-X., Zhang, Q., Chang, G.
Deposit date:2010-04-15
Release date:2010-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structure of a cation-bound multidrug and toxic compound extrusion transporter.
Nature, 467, 2010
3MKU
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STRUCTURE OF A CATION-BOUND MULTIDRUG AND TOXIN COMPOUND EXTRUSION (MATE) TRANSPORTER
Descriptor:Multi antimicrobial extrusion protein (Na(+)/drug antiporter) MATE-like MDR efflux pump, RUBIDIUM ION
Authors:He, X., Szewczyk, P., Karyakin, A., Evin, M., Hong, W.-X., Zhang, Q., Chang, G.
Deposit date:2010-04-15
Release date:2010-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of a cation-bound multidrug and toxic compound extrusion transporter.
Nature, 467, 2010
4KSB
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STRUCTURES OF P-GLYCOPROTEIN REVEAL ITS CONFORMATIONAL FLEXIBILITY AND AN EPITOPE ON THE NUCLEOTIDE-BINDING DOMAIN
Descriptor:Multidrug resistance protein 1A
Authors:Ward, A., Szewczyk, P., Grimard, V., Lee, C.-W., Martinez, L., Doshi, R., Caya, A., Villaluz, M., Pardon, E., Cregger, C., Swartz, D.J., Falson, P., Urbatsch, I., Govaerts, C., Steyaert, J., Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (3.8001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSC
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STRUCTURES OF P-GLYCOPROTEIN REVEAL ITS CONFORMATIONAL FLEXIBILITY AND AN EPITOPE ON THE NUCLEOTIDE-BINDING DOMAIN
Descriptor:Multidrug resistance protein 1A
Authors:Ward, A., Szewczyk, P., Grimard, V., Lee, C.-W., Martinez, L., Doshi, R., Caya, A., Villaluz, M., Pardon, E., Cregger, C., Swartz, D.J., Falson, P., Urbatsch, I., Govaerts, C., Steyaert, J., Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSD
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STRUCTURES OF P-GLYCOPROTEIN REVEAL ITS CONFORMATIONAL FLEXIBILITY AND AN EPITOPE ON THE NUCLEOTIDE-BINDING DOMAIN
Descriptor:Multidrug resistance protein 1A, R2 protein
Authors:Ward, A., Szewczyk, P., Grimard, V., Lee, C.-W., Martinez, L., Doshi, R., Caya, A., Villaluz, M., Pardon, E., Cregger, C., Swartz, D.J., Falson, P., Urbatsch, I., Govaerts, C., Steyaert, J., Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (4.1001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LSG
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STRUCTURE OF MOUSE P-GLYCOPROTEIN
Descriptor:Multidrug resistance protein 1A, MERCURY (II) ION
Authors:Chang, G., Szewczyk, P.
Deposit date:2013-07-22
Release date:2013-07-31
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:

4Q9H
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P-GLYCOPROTEIN AT 3.4 A RESOLUTION
Descriptor:Multidrug resistance protein 1A
Authors:McGrath, A.P., Szewczyk, P., Chang, G.
Deposit date:2014-05-01
Release date:2015-03-04
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
4Q9I
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P-GLYCOPROTEIN COCRYSTALLISED WITH QZ-ALA
Descriptor:Multidrug resistance protein 1A, (30F)A(30F)A(30F)A Peptide
Authors:McGrath, A.P., Szewczyk, P., Chang, G.
Deposit date:2014-05-01
Release date:2015-03-04
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (3.781 Å)
Cite:Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
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