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1GRZ
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A PREORGANIZED ACTIVE SITE IN THE CRYSTAL STRUCTURE OF THE TETRAHYMENA RIBOZYME
Descriptor:LSU R-RNA GROUP I INTRON
Authors:Golden, B.L., Gooding, A.R., Podell, E.R., Cech, T.R.
Deposit date:1998-09-14
Release date:1998-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:A preorganized active site in the crystal structure of the Tetrahymena ribozyme.
Science, 282, 1998
1HR2
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CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON.
Descriptor:P4-P6 DELC209 MUTANT RNA RIBOZYME DOMAIN, MAGNESIUM ION
Authors:Juneau, K., Podell, E.R., Harrington, D.J., Cech, T.R.
Deposit date:2000-12-20
Release date:2001-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions.
Structure, 9, 2001
1GID
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CRYSTAL STRUCTURE OF A GROUP I RIBOZYME DOMAIN: PRINCIPLES OF RNA PACKING
Descriptor:P4-P6 RNA RIBOZYME DOMAIN, MAGNESIUM ION, COBALT HEXAMMINE(III)
Authors:Cate, J.H., Gooding, A.R., Podell, E., Zhou, K., Golden, B.L., Kundrot, C.E., Cech, T.R., Doudna, J.A.
Deposit date:1996-08-22
Release date:1996-12-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a group I ribozyme domain: principles of RNA packing.
Science, 273, 1996
1QZG
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CRYSTAL STRUCTURE OF POT1 (PROTECTION OF TELOMERE)- SSDNA COMPLEX
Descriptor:telomeric single-stranded DNA, Protection of telomeres protein 1, THYMIDINE-5'-PHOSPHATE
Authors:Lei, M., Podell, E.R., Baumann, P., Cech, T.R.
Deposit date:2003-09-16
Release date:2003-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
Nature, 426, 2003
1QZH
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CRYSTAL STRUCTURE OF POT1 (PROTECTION OF TELOMERE)- SSDNA COMPLEX
Descriptor:telomeric single-stranded DNA, Protection of telomeres protein 1
Authors:Lei, M., Podell, E.R., Baumann, P., Cech, T.R.
Deposit date:2003-09-16
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
Nature, 426, 2003
1X8W
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STRUCTURE OF THE TETRAHYMENA RIBOZYME: BASE TRIPLE SANDWICH AND METAL ION AT THE ACTIVE SITE
Descriptor:Tetrahymena ribozyme RNA, MAGNESIUM ION
Authors:Guo, F., Gooding, A.R., Cech, T.R.
Deposit date:2004-08-18
Release date:2004-11-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site.
Mol.Cell, 16, 2004
1XJV
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CRYSTAL STRUCTURE OF HUMAN POT1 BOUND TO TELOMERIC SINGLE-STRANDED DNA (TTAGGGTTAG)
Descriptor:hT10 d(TTAGGGTTAG), Protection of telomeres 1
Authors:Lei, M., Podell, E.R., Cech, T.R.
Deposit date:2004-09-25
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
Nat.Struct.Mol.Biol., 11, 2004
2B2A
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CRYSTAL STRUCTURE OF THE TEN DOMAIN OF THE TELOMERASE REVERSE TRANSCRIPTASE
Descriptor:Telomerase reverse transcriptase
Authors:Jacobs, S.A., Podell, E.R., Cech, T.R.
Deposit date:2005-09-18
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.
Nat.Struct.Mol.Biol., 13, 2006
2I46
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CRYSTAL STRUCTURE OF HUMAN TPP1
Descriptor:Adrenocortical dysplasia protein homolog
Authors:Wang, F., Podell, E.R., Zaug, A.J., Yang, Y.T., Baciu, P., Else, T., Hammer, G.D., Cech, T.R., Lei, M.
Deposit date:2006-08-21
Release date:2006-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The POT1-TPP1 telomere complex is a telomerase processivity factor.
Nature, 445, 2007
3KJO
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CRYSTAL STRUCTURE OF HPOT1V2-DTRUD(AGGGTTAG)
Descriptor:Protection of telomeres protein 1, DNA/RNA (5'-D(*T)-R(P*U)-D(P*AP*GP*GP*GP*TP*TP*AP*G)-3')
Authors:Nandakumar, J., Cech, T.R., Podell, E.R.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KJP
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CRYSTAL STRUCTURE OF HPOT1V2-GGTTAGGGTTAG
Descriptor:Protection of telomeres protein 1, 5'-D(*G*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'
Authors:Nandakumar, J., Cech, T.R., Podell, E.R.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
4NBO
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HUMAN STEROID RECEPTOR RNA ACTIVATOR PROTEIN CARBOXY-TERMINAL DOMAIN
Descriptor:Steroid receptor RNA activator 1
Authors:Mckay, D.B., Xi, L., Barthel, K.K.B., Cech, T.C.
Deposit date:2013-10-23
Release date:2014-02-05
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (2.807 Å)
Cite:Structure and function of steroid receptor RNA activator protein, the proposed partner of SRA noncoding RNA.
J.Mol.Biol., 426, 2014
6BJX
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GROUP I SELF-SPLICING INTRON P4-P6 DOMAIN MUTANT U131A (WITH ISOPROPANOL SOAKING)
Descriptor:Group I self-splicing intron P4-P6 domain, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2017-11-07
Release date:2018-07-04
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8L
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GROUP I SELF-SPLICING INTRON P4-P6 DOMAIN MUTANT U131A (WITHOUT ISOPROPANOL SOAKING)
Descriptor:Group I self-splicing intron, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2018-04-26
Release date:2018-07-18
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (3.140215 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8M
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GROUP I SELF-SPLICING INTRON P4-P6 DOMAIN MUTANT A125U/G126U
Descriptor:Group I self-splicing intron, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2018-04-26
Release date:2018-07-04
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8N
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GROUP I SELF-SPLICING INTRON P4-P6 DOMAIN MUTANT G134A/U185AA
Descriptor:Group I self-splicing intron, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2018-04-26
Release date:2018-07-18
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (3.954271 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8O
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GROUP I SELF-SPLICING INTRON P4-P6 DOMAIN MUTANT A230U
Descriptor:Group I self-splicing intron, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2018-04-26
Release date:2018-07-04
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.801125 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
1IQT
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SOLUTION STRUCTURE OF THE C-TERMINAL RNA-BINDING DOMAIN OF HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 (AUF1)
Descriptor:heterogeneous nuclear ribonucleoprotein D0
Authors:Katahira, M., Miyanoiri, Y., Enokizono, Y., Matsuda, G., Nagata, T., Ishikawa, F., Uesugi, S.
Deposit date:2001-08-01
Release date:2002-08-07
Last modified:2018-06-27
Method:SOLUTION NMR
Cite:Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA.
J.Mol.Biol., 311, 2001
1U6B
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CRYSTAL STRUCTURE OF A SELF-SPLICING GROUP I INTRON WITH BOTH EXONS
Descriptor:197-MER, 5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*CP*CP*AP*GP*AP*CP*GP *GP*CP*C)-3', 5'-R(*CP*AP*(5MU))-3', ...
Authors:Adams, P.L., Stahley, M.R., Kosek, A.B., Wang, J., Strobel, S.A.
Deposit date:2004-07-29
Release date:2004-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of a Self-Splicing Group I Intron with Both Exons.
Nature, 430, 2004
1WTB
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COMPLEX STRUCTURE OF THE C-TERMINAL RNA-BINDING DOMAIN OF HNRNP D (AUF1) WITH TELOMERE DNA
Descriptor:5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0
Authors:Enokizono, Y., Konishi, Y., Nagata, K., Ouhashi, K., Uesugi, S., Ishikawa, F., Katahira, M.
Deposit date:2004-11-22
Release date:2005-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D
J.Biol.Chem., 280, 2005
1X0F
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COMPLEX STRUCTURE OF THE C-TERMINAL RNA-BINDING DOMAIN OF HNRNP D(AUF1) WITH TELOMERIC DNA
Descriptor:5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0
Authors:Enokizono, Y., Konishi, Y., Nagata, K., Ouhashi, K., Uesugi, S., Ishikawa, F., Katahira, M.
Deposit date:2005-03-22
Release date:2005-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D.
J.Biol.Chem., 280, 2005
1ZZN
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CRYSTAL STRUCTURE OF A GROUP I INTRON/TWO EXON COMPLEX THAT INCLUDES ALL CATALYTIC METAL ION LIGANDS.
Descriptor:197-MER, 5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*CP*CP*AP*GP*AP*CP*GP*GP*CP*C)-3', 5'-R(*CP*AP*(5MU))-3', ...
Authors:Stahley, M.R., Strobel, S.A.
Deposit date:2005-06-14
Release date:2005-08-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Structural evidence for a two-metal-ion mechanism of group I intron splicing.
Science, 309, 2005
376D
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A ZIPPER-LIKE DNA DUPLEX D(GCGAAAGCT)
Descriptor:DNA (5'-D(*GP*(CBR)P*GP*AP*AP*AP*GP*CP*T)-3'), COBALT HEXAMMINE(III)
Authors:Cruse, W.B.T., Shepard, W., Prange, T., delalFortelle, E., Fourme, R.
Deposit date:1998-01-22
Release date:1999-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A zipper-like duplex in DNA: the crystal structure of d(GCGAAAGCT) at 2.1 A resolution.
Structure, 6, 1998