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1GID
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BU of 1gid by Molmil
CRYSTAL STRUCTURE OF A GROUP I RIBOZYME DOMAIN: PRINCIPLES OF RNA PACKING
Descriptor: COBALT HEXAMMINE(III), MAGNESIUM ION, P4-P6 RNA RIBOZYME DOMAIN
Authors:Cate, J.H, Gooding, A.R, Podell, E, Zhou, K, Golden, B.L, Kundrot, C.E, Cech, T.R, Doudna, J.A.
Deposit date:1996-08-22
Release date:1996-12-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a group I ribozyme domain: principles of RNA packing.
Science, 273, 1996
1GRZ
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BU of 1grz by Molmil
A PREORGANIZED ACTIVE SITE IN THE CRYSTAL STRUCTURE OF THE TETRAHYMENA RIBOZYME
Descriptor: LSU R-RNA GROUP I INTRON
Authors:Golden, B.L, Gooding, A.R, Podell, E.R, Cech, T.R.
Deposit date:1998-09-14
Release date:1998-11-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (5 Å)
Cite:A preorganized active site in the crystal structure of the Tetrahymena ribozyme.
Science, 282, 1998
6W6W
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BU of 6w6w by Molmil
Cryo-EM structure of CST bound to telomeric single-stranded DNA
Descriptor: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ...
Authors:Lim, C, Barbour, A.T, Zaug, A.J, Goodrich, K.J, McKay, A.E, Wuttke, D.S, Cech, T.R.
Deposit date:2020-03-17
Release date:2020-06-03
Last modified:2020-06-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The structure of human CST reveals a decameric assembly bound to telomeric DNA.
Science, 368, 2020
1HR2
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BU of 1hr2 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON.
Descriptor: MAGNESIUM ION, P4-P6 DELC209 MUTANT RNA RIBOZYME DOMAIN
Authors:Juneau, K, Podell, E.R, Harrington, D.J, Cech, T.R.
Deposit date:2000-12-20
Release date:2001-04-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions.
Structure, 9, 2001
2I46
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BU of 2i46 by Molmil
Crystal structure of human TPP1
Descriptor: Adrenocortical dysplasia protein homolog
Authors:Wang, F, Podell, E.R, Zaug, A.J, Yang, Y.T, Baciu, P, Else, T, Hammer, G.D, Cech, T.R, Lei, M.
Deposit date:2006-08-21
Release date:2006-11-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The POT1-TPP1 telomere complex is a telomerase processivity factor.
Nature, 445, 2007
3KJP
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BU of 3kjp by Molmil
Crystal Structure of hPOT1V2-GGTTAGGGTTAG
Descriptor: 5'-D(*G*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3', Protection of telomeres protein 1
Authors:Nandakumar, J, Cech, T.R, Podell, E.R.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KJO
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BU of 3kjo by Molmil
Crystal Structure of hPOT1V2-dTrUd(AGGGTTAG)
Descriptor: DNA/RNA (5'-D(*T)-R(P*U)-D(P*AP*GP*GP*GP*TP*TP*AP*G)-3'), Protection of telomeres protein 1
Authors:Nandakumar, J, Cech, T.R, Podell, E.R.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
2B2A
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BU of 2b2a by Molmil
Crystal Structure of the TEN domain of the Telomerase Reverse Transcriptase
Descriptor: Telomerase reverse transcriptase
Authors:Jacobs, S.A, Podell, E.R, Cech, T.R.
Deposit date:2005-09-18
Release date:2006-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.
Nat.Struct.Mol.Biol., 13, 2006
1QZG
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BU of 1qzg by Molmil
Crystal structure of Pot1 (protection of telomere)- ssDNA complex
Descriptor: Protection of telomeres protein 1, THYMIDINE-5'-PHOSPHATE, telomeric single-stranded DNA
Authors:Lei, M, Podell, E.R, Baumann, P, Cech, T.R.
Deposit date:2003-09-16
Release date:2003-11-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
Nature, 426, 2003
1QZH
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BU of 1qzh by Molmil
Crystal structure of Pot1 (protection of telomere)- ssDNA complex
Descriptor: Protection of telomeres protein 1, telomeric single-stranded DNA
Authors:Lei, M, Podell, E.R, Baumann, P, Cech, T.R.
Deposit date:2003-09-16
Release date:2003-11-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
Nature, 426, 2003
1X8W
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BU of 1x8w by Molmil
Structure of the Tetrahymena Ribozyme: Base Triple Sandwich and Metal Ion at the Active Site
Descriptor: MAGNESIUM ION, Tetrahymena ribozyme RNA
Authors:Guo, F, Gooding, A.R, Cech, T.R.
Deposit date:2004-08-18
Release date:2004-11-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site.
Mol.Cell, 16, 2004
1XJV
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BU of 1xjv by Molmil
Crystal structure of human POT1 bound to telomeric single-stranded DNA (TTAGGGTTAG)
Descriptor: Protection of telomeres 1, hT10 d(TTAGGGTTAG)
Authors:Lei, M, Podell, E.R, Cech, T.R.
Deposit date:2004-09-25
Release date:2004-12-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
Nat.Struct.Mol.Biol., 11, 2004
8FYH
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BU of 8fyh by Molmil
G4 RNA-mediated PRC2 dimer
Descriptor: G4 RNA, Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, ...
Authors:Song, J, Kasinath, V.
Deposit date:2023-01-26
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for inactivation of PRC2 by G-quadruplex RNA.
Science, 381, 2023
4NBO
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BU of 4nbo by Molmil
Human steroid receptor RNA activator protein carboxy-terminal domain
Descriptor: Steroid receptor RNA activator 1
Authors:Mckay, D.B, Xi, L, Barthel, K.K.B, Cech, T.C.
Deposit date:2013-10-23
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.807 Å)
Cite:Structure and function of steroid receptor RNA activator protein, the proposed partner of SRA noncoding RNA.
J.Mol.Biol., 426, 2014
6BJX
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BU of 6bjx by Molmil
Group I self-splicing intron P4-P6 domain mutant U131A (with isopropanol soaking)
Descriptor: Group I self-splicing intron P4-P6 domain, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2017-11-07
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8M
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BU of 6d8m by Molmil
Group I self-splicing intron P4-P6 domain mutant A125U/G126U
Descriptor: Group I self-splicing intron, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2018-04-26
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8O
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BU of 6d8o by Molmil
Group I self-splicing intron P4-P6 domain mutant A230U
Descriptor: Group I self-splicing intron, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2018-04-26
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.80112481 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8L
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BU of 6d8l by Molmil
Group I self-splicing intron P4-P6 domain mutant U131A (without isopropanol soaking)
Descriptor: Group I self-splicing intron, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2018-04-26
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1402154 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8N
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BU of 6d8n by Molmil
Group I self-splicing intron P4-P6 domain mutant G134A/U185AA
Descriptor: Group I self-splicing intron, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2018-04-26
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.95427132 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
376D
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BU of 376d by Molmil
A ZIPPER-LIKE DNA DUPLEX D(GCGAAAGCT)
Descriptor: COBALT HEXAMMINE(III), DNA (5'-D(*GP*(CBR)P*GP*AP*AP*AP*GP*CP*T)-3')
Authors:Cruse, W.B.T, Shepard, W, Prange, T, delalFortelle, E, Fourme, R.
Deposit date:1998-01-22
Release date:1999-10-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A zipper-like duplex in DNA: the crystal structure of d(GCGAAAGCT) at 2.1 A resolution.
Structure, 6, 1998
1IQT
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BU of 1iqt by Molmil
Solution structure of the C-terminal RNA-binding domain of heterogeneous nuclear ribonucleoprotein D0 (AUF1)
Descriptor: heterogeneous nuclear ribonucleoprotein D0
Authors:Katahira, M, Miyanoiri, Y, Enokizono, Y, Matsuda, G, Nagata, T, Ishikawa, F, Uesugi, S.
Deposit date:2001-08-01
Release date:2002-08-07
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA.
J.Mol.Biol., 311, 2001
1ZZN
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BU of 1zzn by Molmil
Crystal structure of a group I intron/two exon complex that includes all catalytic metal ion ligands.
Descriptor: 197-MER, 5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*CP*CP*AP*GP*AP*CP*GP*GP*CP*C)-3', 5'-R(*CP*AP*(5MU))-3', ...
Authors:Stahley, M.R, Strobel, S.A.
Deposit date:2005-06-14
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Structural evidence for a two-metal-ion mechanism of group I intron splicing.
Science, 309, 2005
1U6B
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BU of 1u6b by Molmil
CRYSTAL STRUCTURE OF A SELF-SPLICING GROUP I INTRON WITH BOTH EXONS
Descriptor: 197-MER, 5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*CP*CP*AP*GP*AP*CP*GP *GP*CP*C)-3', 5'-R(*CP*AP*(5MU))-3', ...
Authors:Adams, P.L, Stahley, M.R, Kosek, A.B, Wang, J, Strobel, S.A.
Deposit date:2004-07-29
Release date:2004-08-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of a Self-Splicing Group I Intron with Both Exons.
Nature, 430, 2004
1WTB
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BU of 1wtb by Molmil
Complex structure of the C-terminal RNA-binding domain of hnRNP D (AUF1) with telomere DNA
Descriptor: 5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0
Authors:Enokizono, Y, Konishi, Y, Nagata, K, Ouhashi, K, Uesugi, S, Ishikawa, F, Katahira, M.
Deposit date:2004-11-22
Release date:2005-04-05
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D
J.Biol.Chem., 280, 2005
1X0F
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BU of 1x0f by Molmil
Complex structure of the C-terminal RNA-binding domain of hnRNP D(AUF1) with telomeric DNA
Descriptor: 5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0
Authors:Enokizono, Y, Konishi, Y, Nagata, K, Ouhashi, K, Uesugi, S, Ishikawa, F, Katahira, M.
Deposit date:2005-03-22
Release date:2005-04-05
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D.
J.Biol.Chem., 280, 2005

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