Author results

6C1P
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HYPOPP MUTANT
Descriptor:Ion transport protein, PHOSPHATE ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Catterall, W.A., Zheng, N., Jiang, D., Gamal El-Din, T.M.
Deposit date:2018-01-05
Release date:2018-05-16
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
6C1E
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NAVAB NORMOPP MUTANT
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 5-BETA-24-NOR-CHOLANE-3(ALPHA),7(ALPHA),12(ALPHA)-TRIOL, ...
Authors:Catterall, W.A., Zheng, N., Jiang, D., Gamal El-Din, T.M.
Deposit date:2018-01-04
Release date:2018-05-16
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
6C1K
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HYPOPP MUTANT WITH LIGAND1
Descriptor:Ion transport protein, GUANIDINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Catterall, W.A., Zheng, N., Jiang, D., Gamal El-Din, T.M.
Deposit date:2018-01-04
Release date:2018-05-16
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
6C1M
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NAVAB NORMOPP MUTANT
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHAPSO, ...
Authors:Catterall, W.A., Zheng, N., Jiang, D., Gamal El-Din, T.M.
Deposit date:2018-01-04
Release date:2018-05-16
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.518 Å)
Cite:Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
1BYY
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SODIUM CHANNEL IIA INACTIVATION GATE
Descriptor:PROTEIN (SODIUM CHANNEL ALPHA-SUBUNIT)
Authors:Rohl, C.A., Boeckman, F.A., Baker, C., Scheuer, T., Catterall, W.A., Klevit, R.E.
Deposit date:1998-10-21
Release date:1999-10-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the sodium channel inactivation gate.
Biochemistry, 38, 1999
3RVY
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CRYSTAL STRUCTURE OF THE NAVAB VOLTAGE-GATED SODIUM CHANNEL (ILE217CYS, 2.7 A)
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Payandeh, J., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2011-05-06
Release date:2011-07-13
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
3RVZ
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CRYSTAL STRUCTURE OF THE NAVAB VOLTAGE-GATED SODIUM CHANNEL (ILE217CYS, 2.8 A)
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Payandeh, J., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2011-05-06
Release date:2011-07-13
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
3RW0
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CRYSTAL STRUCTURE OF THE NAVAB VOLTAGE-GATED SODIUM CHANNEL (MET221CYS, 2.95 A)
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Payandeh, J., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2011-05-06
Release date:2011-07-13
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
4EKW
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CRYSTAL STRUCTURE OF THE NAVAB VOLTAGE-GATED SODIUM CHANNEL (WILD-TYPE, 3.2 A)
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, PHOSPHATE ION
Authors:Payandeh, J., Gamal El-Din, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2012-04-10
Release date:2012-05-16
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Crystal structure of a voltage-gated sodium channel in two potentially inactivated states.
Nature, 486, 2012
4MS2
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STRUCTURAL BASIS OF CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-18
Release date:2013-11-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MTF
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STRUCTURAL BASIS OF CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, CALCIUM ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-19
Release date:2013-11-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MTG
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, CALCIUM ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-19
Release date:2013-11-27
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (3.296 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MTO
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, CALCIUM ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-19
Release date:2013-11-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.402 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MVM
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-24
Release date:2013-11-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.1997 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MVO
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-24
Release date:2013-11-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.296 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MVQ
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, CALCIUM ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Gilbert, Q.M., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-24
Release date:2013-11-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MVR
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, MANGANESE (II) ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Gilbert, Q.M., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-24
Release date:2013-11-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.196 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MVS
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, CADMIUM ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-24
Release date:2013-11-27
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (3.299 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MVU
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-24
Release date:2013-11-27
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (3.198 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MVZ
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, CALCIUM ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-24
Release date:2013-11-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MW3
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, CALCIUM ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-24
Release date:2013-11-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.2997 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
4MW8
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STRUCTURAL BASIS FOR CA2+ SELECTIVITY OF A VOLTAGE-GATED CALCIUM CHANNEL
Descriptor:Ion transport protein, CALCIUM ION, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2013-09-24
Release date:2013-11-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.256 Å)
Cite:Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
5KLB
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CRYSTAL STRUCTURE OF THE CAVAB VOLTAGE-GATED CALCIUM CHANNEL(WILD-TYPE, 2.7A)
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ...
Authors:Tang, L., Gamal EL-Din, T.M., Swanson, T.M., Pryde, D.C., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2016-06-23
Release date:2016-08-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
5KLG
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STRUCTURE OF CAVAB(W195Y) IN COMPLEX WITH BR-DIHYDROPYRIDINE DERIVATIVE UK-59811
Descriptor:Ion transport protein, CALCIUM ION, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Tang, L., Gamal EL-Din, T.M., Swanson, T.M., Pryde, D.C., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2016-06-24
Release date:2016-08-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
5KLS
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STRUCTURE OF CAVAB IN COMPLEX WITH BR-DIHYDROPYRIDINE DERIVATIVE UK-59811
Descriptor:Ion transport protein, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ...
Authors:Tang, L., Gamal EL-Din, T.M., Swanson, T.M., Pryde, D.C., Scheuer, T., Zheng, N., Catterall, W.A.
Deposit date:2016-06-25
Release date:2016-08-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.299 Å)
Cite:Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
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