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7RH2
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BU of 7rh2 by Molmil
IRF4 Transcription factor mutant -K59R
Descriptor: DNA (5'-D(*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*AP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*GP*TP*TP*G)-3'), ICSAT transcription factor
Authors:Williams, S.J, Sundararaj, S, Casarotto, M.G.
Deposit date:2021-07-16
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:The molecular basis for the development of adult T-cell leukemia/lymphoma in patients with an IRF4 K59R mutation.
Protein Sci., 31, 2022
1JZP
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BU of 1jzp by Molmil
Modified Peptide A (D18-A1) of the Rabbit Skeletal Dihydropyridine Receptor
Descriptor: Skeletal Dihydropydrine Receptor
Authors:Green, D, Pace, S, Sakowska, M, Dulhunty, A.F, Casarotto, M.G.
Deposit date:2001-09-17
Release date:2002-03-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha-helical dihydropyridine receptor segment.
Biochem.J., 370, 2003
7JM4
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BU of 7jm4 by Molmil
IRF Transcription Factor
Descriptor: Interferon regulatory factor 4, Interferon-Stimulated Response Elements
Authors:Sundararaj, S, Williams, S.J, Casarotto, M.G.
Deposit date:2020-07-31
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural determinants of the IRF4/DNA homodimeric complex.
Nucleic Acids Res., 49, 2021
1DU1
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BU of 1du1 by Molmil
PEPTIDE FRAGMENT THR671-LEU690 OF THE RABBIT SKELETAL DIHYDROPYRIDINE RECEPTOR
Descriptor: SKELETAL DIHYDROPYRIDINE RECEPTOR
Authors:Casarotto, M, Dulhunty, A.
Deposit date:2000-01-13
Release date:2000-07-19
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:A structural requirement for activation of skeletal ryanodine receptors by peptides of the dihydropyridine receptor II-III loop.
J.Biol.Chem., 275, 2000
5V3Q
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BU of 5v3q by Molmil
Human GSTO1-1 complexed with ML175
Descriptor: Glutathione S-transferase omega-1, N-{3-[(2-chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide, SULFATE ION
Authors:Oakley, A.J.
Deposit date:2017-03-07
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity.
Sci Rep, 7, 2017
4ZW2
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BU of 4zw2 by Molmil
Crystal structure of the Mouse voltage gated calcium channel beta subunit isoform 1a in complex with Alpha Interaction Domain peptide.
Descriptor: TRIETHYLENE GLYCOL, Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-dependent L-type calcium channel subunit beta-1,Voltage-dependent L-type calcium channel subunit beta-1
Authors:Norris, N.C, Oakley, A.J.
Deposit date:2015-05-19
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural and biophysical analyses of the skeletal dihydropyridine receptor beta subunit beta 1a reveal critical roles of domain interactions for stability.
J. Biol. Chem., 292, 2017
3LFL
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BU of 3lfl by Molmil
Crystal Structure of human Glutathione Transferase Omega 1, delta 155
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLUTATHIONE, Glutathione S-transferase omega-1
Authors:Brock, J.
Deposit date:2010-01-18
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel folding and stability defects cause a deficiency of human glutathione transferase omega 1.
J.Biol.Chem., 286, 2011
6PNN
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BU of 6pnn by Molmil
Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-(2-methoxyethyl)-N-methylsulfamoyl)phenyl)acetamide
Descriptor: 2-chloro-N-{4-chloro-3-[(2-methoxyethyl)(methyl)sulfamoyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ...
Authors:Oakley, A.J.
Deposit date:2019-07-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J.Med.Chem., 63, 2020
6PNM
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BU of 6pnm by Molmil
Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(morpholinosulfonyl)phenyl)acetamide
Descriptor: 2-chloro-N-{4-chloro-3-[(morpholin-4-yl)sulfonyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ...
Authors:Oakley, A.J.
Deposit date:2019-07-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J.Med.Chem., 63, 2020
6PNO
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BU of 6pno by Molmil
Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-isopropylsulfamoyl)phenyl)acetamide
Descriptor: 2-chloro-N-{4-chloro-3-[(propan-2-yl)sulfamoyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ...
Authors:Oakley, A.J.
Deposit date:2019-07-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J.Med.Chem., 63, 2020

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