Author results

1DQS
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CRYSTAL STRUCTURE OF DEHYDROQUINATE SYNTHASE (DHQS) COMPLEXED WITH CARBAPHOSPHONATE, NAD+ AND ZN2+
Descriptor:PROTEIN (3-DEHYDROQUINATE SYNTHASE), ZINC ION, CHLORIDE ION, ...
Authors:Carpenter, E.P., Hawkins, A.R., Frost, J.W., Brown, K.A.
Deposit date:1998-04-09
Release date:1999-07-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of dehydroquinate synthase reveals an active site capable of multistep catalysis.
Nature, 394, 1998
2C53
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A COMPARATIVE STUDY OF URACIL DNA GLYCOSYLASES FROM HUMAN AND HERPES SIMPLEX VIRUS TYPE 1
Descriptor:URACIL DNA GLYCOSYLASE, 2'-DEOXYURIDINE, GLYCEROL
Authors:Krusong, K., Carpenter, E.P., Bellmy, S.R.W., Savva, R., Baldwin, G.S.
Deposit date:2005-10-25
Release date:2005-11-28
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006
2C56
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A COMPARATIVE STUDY OF URACIL DNA GLYCOSYLASES FROM HUMAN AND HERPES SIMPLEX VIRUS TYPE 1
Descriptor:URACIL DNA GLYCOSYLASE, SUCROSE
Authors:Krusong, K., Carpenter, E.P., Bellamy, S.R.W., Savva, R., Baldwin, G.S.
Deposit date:2005-10-26
Release date:2005-11-28
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006
2D00
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SUBUNIT F OF V-TYPE ATPASE/SYNTHASE
Descriptor:V-type ATP synthase subunit F, CALCIUM ION
Authors:Makyio, H., Iino, R., Ikeda, C., Imamura, H., Tamakoshi, M., Iwata, M., Stock, D., Bernal, R.A., Carpenter, E.P., Yoshida, M., Yokoyama, K., Iwata, S.
Deposit date:2005-07-21
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a central stalk subunit F of prokaryotic V-type ATPase/synthase from Thermus thermophilus
Embo J., 24, 2005
2JC4
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3'-5' EXONUCLEASE (NEXO) FROM NEISSERIA MENINGITIDIS
Descriptor:EXODEOXYRIBONUCLEASE III, MAGNESIUM ION, SODIUM ION, ...
Authors:Carpenter, E.P., Corbett, A., Thomson, H., Adacha, J., Jensen, K., Bergeron, J., Kasampalidis, I., Exley, R., Winterbotham, M., Tang, C., Baldwin, G., Freemont, P.
Deposit date:2006-12-19
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
2JC5
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APURINIC APYRIMIDINIC (AP) ENDONUCLEASE (NAPE) FROM NEISSERIA MENINGITIDIS
Descriptor:EXODEOXYRIBONUCLEASE, MAGNESIUM ION, BICINE, ...
Authors:Carpenter, E.P., Corbett, A., Thomson, H., Adacha, J., Jensen, K., Bergeron, J., Kasampalidis, I., Exley, R., Winterbotham, M., Tang, C., Baldwin, G.S., Freemont, P.
Deposit date:2006-12-19
Release date:2007-03-06
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
2JH1
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII MICRONEMAL PROTEIN 1
Descriptor:MICRONEMAL PROTEIN 1, ACETATE ION, CHLORIDE ION, ...
Authors:Blumenschein, T.M.A., Friedrich, N., Childs, R.A., Saouros, S., Carpenter, E.P., Campanero-Rhodes, M.A., Simpson, P., Koutroukides, T., Blackman, M.J., Feizi, T., Soldati-Favre, D., Matthews, S.
Deposit date:2007-02-19
Release date:2007-05-22
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Atomic Resolution Insight Into Host Cell Recognition by Toxoplasma Gondii.
Embo J., 26, 2007
2JH7
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII MICRONEMAL PROTEIN 1 BOUND TO 6'-SIALYL-N-ACETYLLACTOSAMINE
Descriptor:MICRONEMAL PROTEIN 1, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Blumenschein, T.M.A., Friedrich, N., Childs, R.A., Saouros, S., Carpenter, E.P., Campanero-Rhodes, M.A., Simpson, P., Koutroukides, T., Blackman, M.J., Feizi, T., Soldati-Favre, D., Matthews, S.
Deposit date:2007-02-20
Release date:2007-05-22
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Atomic Resolution Insight Into Host Cell Recognition by Toxoplasma Gondii.
Embo J., 26, 2007
2JHD
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII MICRONEMAL PROTEIN 1 BOUND TO 3'-SIALYL-N-ACETYLLACTOSAMINE
Descriptor:MICRONEMAL PROTEIN 1, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Blumenschein, T.M.A., Friedrich, N., Childs, R.A., Saouros, S., Carpenter, E.P., Campanero-Rhodes, M.A., Simpson, P., Koutroukides, T., Blackman, M.J., Feizi, T., Soldati-Favre, D., Matthews, S.
Deposit date:2007-02-21
Release date:2007-05-22
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Atomic Resolution Insight Into Host Cell Recognition by Toxoplasma Gondii.
Embo J., 26, 2007
2JLN
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER
Descriptor:MHP1, SODIUM ION, MERCURY (II) ION
Authors:Weyand, S., Shimamura, T., Yajima, S., Suzuki, S., Mirza, O., Krusong, K., Carpenter, E.P., Rutherford, N.G., Hadden, J.M., O'Reilly, J., Ma, P., Saidijam, M., Patching, S.G., Hope, R.J., Norbertczak, H.T., Roach, P.C.J., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2008-09-11
Release date:2008-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter.
Science, 322, 2008
2VOC
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THIOREDOXIN A ACTIVE SITE MUTANTS FORM MIXED DISULFIDE DIMERS THAT RESEMBLE ENZYME-SUBSTRATE REACTION INTERMEDIATE
Descriptor:THIOREDOXIN, DI(HYDROXYETHYL)ETHER
Authors:Kouwen, T.R.H.M., Andrell, J., Schrijver, R., Dubois, J.Y.F., Maher, M.J., Iwata, S., Carpenter, E.P., van Dijl, J.M.
Deposit date:2008-02-13
Release date:2009-03-10
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Thioredoxin A active-site mutants form mixed disulfide dimers that resemble enzyme-substrate reaction intermediates.
J. Mol. Biol., 379, 2008
2VYC
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CRYSTAL STRUCTURE OF ACID INDUCED ARGININE DECARBOXYLASE FROM E. COLI
Descriptor:BIODEGRADATIVE ARGININE DECARBOXYLASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Andrell, J., Hicks, M.G., Palmer, T., Carpenter, E.P., Iwata, S., Maher, M.J.
Deposit date:2008-07-22
Release date:2009-03-31
Last modified:2015-12-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Acid Induced Arginine Decarboxylase from Escherichia Coli: Reversible Decamer Assembly Controls Enzyme Activity.
Biochemistry, 48, 2009
2X57
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2
Descriptor:VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2
Authors:Pike, A.C.W., Barr, A.J., Quigley, A., Burgess Brown, N., de Riso, A., Bullock, A., Berridge, G., Muniz, J.R.C., Chaikaud, A., Vollmar, M., Krojer, T., Ugochukwu, E., von Delft, F., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., Carpenter, E.P.
Deposit date:2010-02-05
Release date:2010-03-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Extracellular Domain of Human Vasoactive Intestinal Polypeptide Receptor 2
To be Published
2XD7
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CRYSTAL STRUCTURE OF THE MACRO DOMAIN OF HUMAN CORE HISTONE H2A
Descriptor:CORE HISTONE MACRO-H2A.2
Authors:Vollmar, M., Phillips, C., Carpenter, E.P., Muniz, J.R.C., Krojer, T., Ugochukwu, E., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Gileadi, O.
Deposit date:2010-04-29
Release date:2010-05-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal Structure of the Macro Domain of Human Core Histone H2A
To be Published
2XDG
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN GROWTH HORMONE RELEASING HORMONE RECEPTOR.
Descriptor:GROWTH HORMONE-RELEASING HORMONE RECEPTOR, MAGNESIUM ION, 1,2-ETHANEDIOL
Authors:Pike, A.C.W., Quigley, A., Barr, A.J., Burgess Brown, N., Shrestha, L., Yang, J., Chaikuad, A., Vollmar, M., Muniz, J.R.C., von Delft, F., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., Carpenter, E.P.
Deposit date:2010-04-30
Release date:2010-06-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor.
To be Published
2XUT
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CRYSTAL STRUCTURE OF A PROTON DEPENDENT OLIGOPEPTIDE (POT) FAMILY TRANSPORTER.
Descriptor:PROTON/PEPTIDE SYMPORTER FAMILY PROTEIN
Authors:Newstead, S., Drew, D., Cameron, A.D., Postis, V.L., Xia, X., Fowler, P.W., Ingram, J.C., Carpenter, E.P., Sansom, M.S.P., McPherson, M.J., Baldwin, S.A., Iwata, S.
Deposit date:2010-10-21
Release date:2010-12-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal Structure of a Prokaryotic Homologue of the Mammalian Oligopeptide-Proton Symporters, Pept1 and Pept2.
Embo J., 30, 2011
2XVT
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STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN RAMP2
Descriptor:RECEPTOR ACTIVITY-MODIFYING PROTEIN 2, CALCIUM ION
Authors:Quigley, A., Pike, A.C.W., Burgess-Brown, N., Krojer, T., Shrestha, L., Goubin, S., Kim, J., Das, S., Muniz, J.R.C., Canning, P., Chaikuad, A., Vollmar, M., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bountra, C., Barr, A.J., Carpenter, E.P.
Deposit date:2010-10-31
Release date:2010-12-29
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the Extracellular Domain of Human Ramp2
To be Published
2YPT
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CRYSTAL STRUCTURE OF THE HUMAN NUCLEAR MEMBRANE ZINC METALLOPROTEASE ZMPSTE24 MUTANT (E336A) IN COMPLEX WITH A SYNTHETIC CSIM TETRAPEPTIDE FROM THE C-TERMINUS OF PRELAMIN A
Descriptor:CAAX PRENYL PROTEASE 1 HOMOLOG, PRELAMIN-A/C, ZINC ION
Authors:Pike, A.C.W., Dong, Y.Y., Quigley, A., Dong, L., Savitsky, P., Cooper, C.D.O., Chaikuad, A., Goubin, S., Shrestha, L., Li, Q., Mukhopadhyay, S., Yang, J., Xia, X., Shintre, C.A., Barr, A.J., Berridge, G., Chalk, R., Bray, J.E., von Delft, F., Bullock, A., Bountra, C., Arrowsmith, C.H., Edwards, A., Burgess-Brown, N., Carpenter, E.P.
Deposit date:2012-11-01
Release date:2012-12-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
3F53
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII MICRONEMAL PROTEIN 1 BOUND TO 2F-3'SIALACNAC
Descriptor:Micronemal protein 1, CHLORIDE ION, O-SIALIC ACID, ...
Authors:Garnett, J.A.
Deposit date:2008-11-03
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.
Protein Sci., 18, 2009
3F5A
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII MICRONEMAL PROTEIN 1 BOUND TO 3'SIALACNAC1-3
Descriptor:Micronemal protein 1, CHLORIDE ION, O-SIALIC ACID, ...
Authors:Garnett, J.A., Liu, Y., Feizi, T., Matthews, S.J.
Deposit date:2008-11-03
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.
Protein Sci., 18, 2009
3F5E
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII MICRONEMAL PROTEIN 1 BOUND TO 2'F-3'SIALACNAC1-3
Descriptor:Micronemal protein 1, CHLORIDE ION, O-SIALIC ACID, ...
Authors:Garnett, J.A., Liu, Y., Feizi, T., Matthews, S.J.
Deposit date:2008-11-03
Release date:2009-07-28
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.
Protein Sci., 18, 2009
3FVQ
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CRYSTAL STRUCTURE OF THE NUCLEOTIDE BINDING DOMAIN FBPC COMPLEXED WITH ATP
Descriptor:Fe(3+) ions import ATP-binding protein fbpC, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION
Authors:Newstead, S., Bilton, P., Carpenter, E.P., Campopiano, D., Iwata, S.
Deposit date:2009-01-16
Release date:2009-08-25
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into how nucleotide-binding domains power ABC transport.
Structure, 17, 2009
3MDZ
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CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE VII [ISOFORM 1], CA7
Descriptor:Carbonic anhydrase 7, ZINC ION, 6-ethoxy-1,3-benzothiazole-2-sulfonamide, ...
Authors:Ugochukwu, E., Shafqat, N., Pilka, E., Chaikuad, A., Krojer, T., Muniz, J., Kim, J., Bray, J., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Carpenter, E.P., Yue, W.W., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-06-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7
to be published
3URI
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ENDOTHIAPEPSIN-DB5 COMPLEX.
Descriptor:Endothiapepsin, DB5 peptide
Authors:Bailey, D., Sanz-Aparicio, J., Albert, A., Cooper, J.B.
Deposit date:2011-11-22
Release date:2012-04-18
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.
Acta Crystallogr.,Sect.D, 68, 2012
3URJ
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TYPE IV NATIVE ENDOTHIAPEPSIN
Descriptor:Endothiapepsin, SULFATE ION
Authors:Bailey, D., Cooper, J.B.
Deposit date:2011-11-22
Release date:2012-04-04
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.
Acta Crystallogr.,Sect.D, 68, 2012
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