Author results

6G13
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C-TERMINAL DOMAIN OF MERS-COV NUCLEOCAPSID
Descriptor:Nucleoprotein, trimethylamine oxide, DI(HYDROXYETHYL)ETHER, ...
Authors:Nguyen, T.H.V., Ferron, F.P., Lichiere, J., Canard, B., Papageorgiou, N., Coutard, B.
Deposit date:2018-03-20
Release date:2019-02-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure and oligomerization state of the C-terminal region of the Middle East respiratory syndrome coronavirus nucleoprotein.
Acta Crystallogr D Struct Biol, 75, 2019
5MQX
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NMR SOLUTION STRUCTURE OF MACRO DOMAIN FROM VENEZUELAN EQUINE ENCEPHALITIS VIRUS(VEEV) IN COMPLEX WITH ADP-RIBOSE
Descriptor:Non-structural protein3, ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Makrynitsa, G.I., Ntonti, D., Marousis, K.D., Matsoukas, M.T., Papageorgiou, N., Coutard, B., Bentrop, D., Spyroulias, G.A.
Deposit date:2016-12-21
Release date:2018-07-04
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose.
J.Struct.Biol., 206, 2019
5NJU
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FLAVIVIRUS NS5 DOMAIN
Descriptor:Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, MAGNESIUM ION
Authors:Talapatra, S.K., Chatrin, C., Kozielski, F.
Deposit date:2017-03-29
Release date:2018-01-24
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping.
Oncotarget, 9, 2018
5NJV
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FLAVIVIRUS NS5 DOMAIN
Descriptor:NS5, S-ADENOSYLMETHIONINE, CHLORIDE ION
Authors:Talapatra, S.K., Chatrin, C., Kozielski, F.
Deposit date:2017-03-29
Release date:2018-01-24
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping.
Oncotarget, 9, 2018
5NFY
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SARS-COV NSP10/NSP14 DYNAMIC COMPLEX
Descriptor:Polyprotein 1ab, ZINC ION, DI(HYDROXYETHYL)ETHER
Authors:Ferron, F., Gluais, L., Vonrhein, C., Bricogne, G., Canard, B., Imbert, I.
Deposit date:2017-03-16
Release date:2018-01-10
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.382 Å)
Cite:Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5IQ5
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NMR SOLUTION STRUCTURE OF MAYARO VIRUS MACRO DOMAIN
Descriptor:Macro domain
Authors:Melekis, E., Tsika, A.C., Bentrop, D., Papageorgiou, N., Coutard, B., Spyroulias, G.A.
Deposit date:2016-03-10
Release date:2017-12-20
Last modified:2019-06-19
Method:SOLUTION NMR
Cite:Deciphering the Nucleotide and RNA Binding Selectivity of the Mayaro Virus Macro Domain.
J.Mol.Biol., 431, 2019
5ISN
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NMR SOLUTION STRUCTURE OF MACRO DOMAIN FROM VENEZUELAN EQUINE ENCEPHALITIS VIRUS
Descriptor:Non-structural polyprotein
Authors:Makrynitsa, G.I., Ntonti, D., Marousis, K.D., Tsika, A.C., Papageorgiou, N., Coutard, B., Bentrop, D., Spyroulias, G.A.
Deposit date:2016-03-15
Release date:2017-11-29
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose.
J.Struct.Biol., 206, 2019
5LTF
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CRYSTAL STRUCTURE OF LYMPHOCYTIC CHORIOMENINGITIS MAMMARENAVIRUS ENDONUCLEASE COMPLEXED WITH CATALYTIC IONS
Descriptor:RNA-directed RNA polymerase L, MAGNESIUM ION
Authors:Saez-Ayala, M., Yekwa, E.L., Canard, B., Ferron, F.
Deposit date:2016-09-06
Release date:2017-09-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
5LTN
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CRYSTAL STRUCTURE OF LYMPHOCYTIC CHORIOMENINGITIS MAMMARENAVIRUS ENDONUCLEASE COMPLEXED WITH DPBA
Descriptor:RNA-directed RNA polymerase L, MAGNESIUM ION, GLYCEROL, ...
Authors:Saez-Ayala, M., Yekwa, E.L., Canard, B., Alvarez, K., Ferron, F.
Deposit date:2016-09-07
Release date:2017-09-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
5LTS
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CRYSTAL STRUCTURE OF LYMPHOCYTIC CHORIOMENINGITIS MAMMARENAVIRUS ENDONUCLEASE MUTANT D118A
Descriptor:RNA-directed RNA polymerase L, CHLORIDE ION, SODIUM ION, ...
Authors:Saez-Ayala, M., Yekwa, E.L., Canard, B., Alvarez, K., Ferron, F.
Deposit date:2016-09-07
Release date:2017-09-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
5T2T
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CRYSTAL STRUCTURE OF LYMPHOCYTIC CHORIOMENINGITIS MAMMARENAVIRUS ENDONUCLEASE BOUND TO COMPOUND L742001
Descriptor:RNA-directed RNA polymerase L, MANGANESE (II) ION, (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, ...
Authors:Saez-Ayala, M., Yekwa, E.L., Canard, B., Alvarez, K., Ferron, F.
Deposit date:2016-08-24
Release date:2017-09-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.967 Å)
Cite:Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
5LRP
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MOPEIA VIRUS EXONUCLEASE DOMAIN COMPLEXED WITH MAGNESIUM
Descriptor:Nucleoprotein, ZINC ION, MAGNESIUM ION
Authors:Yekwa, E.L., Khourieh, J., Canard, B., Ferron, F.
Deposit date:2016-08-19
Release date:2017-07-05
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.941 Å)
Cite:Activity inhibition and crystal polymorphism induced by active-site metal swapping.
Acta Crystallogr D Struct Biol, 73, 2017
5LS4
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MOPEIA VIRUS EXONUCLEASE DOMAIN COMPLEXED WITH CALCIUM
Descriptor:Nucleoprotein, CALCIUM ION, ZINC ION, ...
Authors:Yekwa, E.L., Canard, B., Ferron, F.
Deposit date:2016-08-22
Release date:2017-07-05
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.469 Å)
Cite:Activity inhibition and crystal polymorphism induced by active-site metal swapping.
Acta Crystallogr D Struct Biol, 73, 2017
5M5B
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CRYSTAL STRUCTURE OF ZIKA VIRUS NS5 METHYLTRANSFERASE
Descriptor:NS5 methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION, ...
Authors:Barral, K., Ortiz Lombardia, M., Coutard, B., Decroly, E., Lichiere, J.
Deposit date:2016-10-21
Release date:2016-12-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives.
J. Virol., 91, 2017
5FVA
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TOSCANA VIRUS NUCLEOCAPSID PROTEIN
Descriptor:NUCLEOPROTEIN, SODIUM ION
Authors:Baklouti, A., Sevajol, M., Goulet, A., Lichiere, J., Ferron, F., Canard, B., Charrel, R.N., Coutard, B., Papageorgiou, N.
Deposit date:2016-02-03
Release date:2016-03-09
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Toscana virus nucleoprotein oligomer organization observed in solution.
Acta Crystallogr D Struct Biol, 73, 2017
4UD1
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STRUCTURE OF THE N TERMINAL DOMAIN OF THE MERS COV NUCLEOCAPSID
Descriptor:N PROTEIN, AMMONIUM ION, IMIDAZOLE, ...
Authors:Papageorgiou, N., Lichiere, J., Ferron, F., Canard, B., Coutard, B.
Deposit date:2014-12-05
Release date:2015-12-02
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural Characterization of the N-Terminal Part of the Mers-Cov Nucleocapsid by X-Ray Diffraction and Small-Angle X-Ray Scattering
Acta Crystallogr.,Sect.D, 72, 2016
4UCJ
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, SULFATE ION
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-03
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCK
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, S-ADENOSYLMETHIONINE
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-03
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCL
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, SULFATE ION
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-03
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCY
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, SULFATE ION
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-05
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCZ
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-05
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UD0
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, SULFATE ION, ZINC ION, ...
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-05
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCI
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, S-ADENOSYLMETHIONINE, ...
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-03
Release date:2015-10-14
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4Y2A
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CRYSTAL STRUCTURE OF COXSACKIE VIRUS B3 3D POLYMERASE IN COMPLEX WITH GPC-N114 INHIBITOR
Descriptor:3D polymerase, 2,2'-[(4-chlorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), SULFATE ION, ...
Authors:Vives-Adrian, L., Ferrer-Orta, C., Verdaguer, N.
Deposit date:2015-02-09
Release date:2015-04-01
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y2C
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M300V 3D POLYMERASE MUTANT OF EMCV
Descriptor:Genome polyprotein, GLYCEROL
Authors:Verdaguer, N., Ferrer-Orta, C., Vives-Adrian, L.
Deposit date:2015-02-09
Release date:2015-04-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015