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1R6A
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STRUCTURE OF THE DENGUE VIRUS 2'O METHYLTRANSFERASE IN COMPLEX WITH S-ADENOSYL HOMOCYSTEINE AND RIBAVIRIN 5' TRIPHOSPHATE
Descriptor:Genome polyprotein, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Benarroch, D., Egloff, M.P., Mulard, L., Romette, J.L., Canard, B.
Deposit date:2003-10-15
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A structural basis for the inhibition of the NS5 dengue virus mRNA 2'-O-methyltransferase domain by ribavirin 5'-triphosphate.
J.Biol.Chem., 279, 2004
1QZ8
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS NSP9
Descriptor:polyprotein 1ab, SULFATE ION
Authors:Egloff, M.P., Ferron, F., Campanacci, V., Longhi, S., Rancurel, C., Dutartre, H., Snijder, E.J., Gorbalenya, A.E., Cambillau, C., Canard, B.
Deposit date:2003-09-16
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world.
Proc.Natl.Acad.Sci.USA, 101, 2004
3CDU
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CRYSTAL STRUCTURE OF COXSACKIEVIRUS B3 RNA-DEPENDENT RNA POLYMERASE (3DPOL) IN COMPLEX WITH A PYROPHOSPHATE
Descriptor:RNA-directed RNA polymerase 3D-POL, CHLORIDE ION, SULFATE ION, ...
Authors:Gruez, A., Selisko, B., Roberts, M., Bricogne, G., Bussetta, C., Canard, B.
Deposit date:2008-02-27
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
3CDW
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CRYSTAL STRUCTURE OF COXSACKIEVIRUS B3 RNA-DEPENDENT RNA POLYMERASE (3DPOL) IN COMPLEX WITH PROTEIN PRIMER VPG AND A PYROPHOSPHATE
Descriptor:RNA-directed RNA polymerase 3D-POL, Protein 3B, CHLORIDE ION, ...
Authors:Gruez, A., Selisko, B., Roberts, M., Bricogne, G., Bussetta, C., Canard, B.
Deposit date:2008-02-27
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
3JSB
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE LYMPHOCYTIC CHORIOMENINGITIS VIRUS L PROTEIN
Descriptor:RNA-directed RNA polymerase
Authors:Morin, B., Jamal, S., Ferron, F.P., Coutard, B., Bricogne, G., Canard, B., Vonrhein, C., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2009-09-10
Release date:2010-09-15
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription
Plos Pathog., 6, 2010
4TU0
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CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
Descriptor:Non-structural polyprotein 3, 2'-5' OLIGOADENYLATE TRIMER, DI(HYDROXYETHYL)ETHER
Authors:Morin, B., Ferron, f.p., Malet, h., Coutard, b., Canard, b.
Deposit date:2014-06-23
Release date:2014-07-09
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
TO BE PUBLISHED
1F3F
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STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX
Descriptor:PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), MAGNESIUM ION, 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, ...
Authors:Meyer, P., Schneider, B., Sarfati, S., Deville-Bonne, D., Guerreiro, C., Boretto, J., Janin, J., Veron, M., Canard, B.
Deposit date:2000-06-02
Release date:2000-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
EMBO J., 19, 2000
1F6T
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STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX
Descriptor:PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), MAGNESIUM ION, 2*-DEOXY-THYMIDINE-5*-ALPHA BORANO DIPHOSPHATE (ISOMER RP)
Authors:Guerreiro, C., Boretto, J., Janin, J., Veron, M., Canard, B., Schneider, B., Sarfati, S., Deville-Bonne, D.
Deposit date:2000-06-23
Release date:2000-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
EMBO J., 19, 2000
1L9K
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DENGUE METHYLTRANSFERASE
Descriptor:RNA-DIRECTED RNA POLYMERASE, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Egloff, M.P., Benarroch, D., Selisko, B., Romette, J.L., Canard, B.
Deposit date:2002-03-25
Release date:2003-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An RNA cap (nucleoside-2'-O-) methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
Embo J., 21, 2002
1MN9
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NDP KINASE MUTANT (H122G) COMPLEX WITH RTP
Descriptor:NDP kinase, MAGNESIUM ION, RIBAVIRIN TRIPHOSPHATE
Authors:Gallois-montbrun, S., Chen, Y., Dutartre, H., Morera, S., Guerreiro, C., Mulard, L., Schneider, B., Janin, J., Canard, B., Veron, M., Deville-bonne, D.
Deposit date:2002-09-05
Release date:2003-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Analysis of the Activation of Ribavirin Analogs by NDP Kinase: Comparison with Other Ribavirin Targets
MOL.PHARMACOL., 63, 2003
2CKW
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THE 2.3 A RESOLUTION STRUCTURE OF THE SAPPORO VIRUS RNA DEPENDANT RNA POLYMERASE.
Descriptor:RNA-DIRECTED RNA POLYMERASE
Authors:Fullerton, S.W.B., Tucker, P.A., Rohayem, J., Coutard, B., Gebhardt, J., Gorbalenya, A., Canard, B.
Deposit date:2006-04-24
Release date:2006-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Characterization of Sapovirus RNA-Dependent RNA Polymerase.
J.Virol., 81, 2007
2H85
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CRYSTAL STRUCTURE OF NSP 15 FROM SARS
Descriptor:Putative orf1ab polyprotein
Authors:Ricagno, S., Egloff, M.P., Ulferts, R., Coutard, B., Nurizzo, D., Campanacci, V., Cambillau, C., Ziebuhr, J., Canard, B.
Deposit date:2006-06-06
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2V6I
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KOKOBERA VIRUS HELICASE
Descriptor:RNA HELICASE, PYROPHOSPHATE 2-
Authors:Speroni, S., De Colibus, L., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2007-07-18
Release date:2008-03-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
2V6J
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KOKOBERA VIRUS HELICASE: MUTANT MET47THR
Descriptor:RNA HELICASE
Authors:Speroni, S., De Colibus, L., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2007-07-18
Release date:2008-03-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
2W5E
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STRUCTURAL AND BIOCHEMICAL ANALYSIS OF HUMAN PATHOGENIC ASTROVIRUS SERINE PROTEASE AT 2.0 ANGSTROM RESOLUTION
Descriptor:PUTATIVE SERINE PROTEASE, CADMIUM ION, CHLORIDE ION
Authors:Speroni, S., Rohayem, J., Nenci, S., Bonivento, D., Robel, I., Barthel, J., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2008-12-10
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Biochemical Analysis of Human Pathogenic Astrovirus Serine Protease at 2.0 A Resolution.
J.Mol.Biol., 387, 2009
2XYQ
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CRYSTAL STRUCTURE OF THE NSP16 NSP10 SARS CORONAVIRUS COMPLEX
Descriptor:PUTATIVE 2'-O-METHYL TRANSFERASE, NON-STRUCTURAL PROTEIN 10, CHLORIDE ION, ...
Authors:Decroly, E., Debarnot, C., Ferron, F., Bouvet, M., Coutard, B., Imbert, I., Gluais, L., Papageorgiou, N., Ortiz-Lombardia, M., Lescar, J., Canard, B.
Deposit date:2010-11-18
Release date:2011-10-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
2XYR
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CRYSTAL STRUCTURE OF THE NSP16 NSP10 SARS CORONAVIRUS COMPLEX
Descriptor:PUTATIVE 2'-O-METHYL TRANSFERASE, NON-STRUCTURAL PROTEIN 10, SODIUM ION, ...
Authors:Decroly, E., Debarnot, C., Ferron, F., Bouvet, M., Coutard, B., Imbert, I., Gluais, L., Papageorgiou, N., Ortiz-Lombardia, M., Lescar, J., Canard, B.
Deposit date:2010-11-18
Release date:2011-10-26
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
2XYV
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CRYSTAL STRUCTURE OF THE NSP16 NSP10 SARS CORONAVIRUS COMPLEX
Descriptor:PUTATIVE 2'-O-METHYL TRANSFERASE, NON-STRUCTURAL PROTEIN 10, SODIUM ION, ...
Authors:Decroly, E., Debarnot, C., Ferron, F., Bouvet, M., Coutard, B., Imbert, I., Gluais, L., Papageorgiou, N., Ortiz-Lombardia, M., Lescar, J., Canard, B.
Deposit date:2010-11-19
Release date:2011-10-26
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex.
Plos Pathog., 7, 2011
3GPG
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF CHIKUNGUNYA VIRUS
Descriptor:Non-structural protein 3
Authors:Malet, H., Jamal, S., Coutard, B., Canard, B.
Deposit date:2009-03-23
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3GPO
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF CHIKUNGUNYA VIRUS IN COMPLEX WITH ADP-RIBOSE
Descriptor:Non-structural protein 3, ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Malet, H., Jamal, S., Coutard, B., Canard, B.
Deposit date:2009-03-23
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3GPQ
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF CHIKUNGUNYA VIRUS IN COMPLEX WITH RNA
Descriptor:Non-structural protein 3, RNA (5'-R(*AP*AP*A)-3')
Authors:Malet, H., Jamal, S., Coutard, B., Canard, B.
Deposit date:2009-03-23
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3GQE
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS
Descriptor:Non-structural protein 3, BICINE
Authors:Jamal, S., Malet, H., Coutard, B., Canard, B.
Deposit date:2009-03-24
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3GQO
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CRYSTAL STRUCTURE OF MACRO DOMAIN OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS IN COMPLEX WITH ADP-RIBOSE
Descriptor:Non-structural protein 3, ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Malet, H., Jamal, S., Coutard, B., Ferron, F., Canard, B.
Deposit date:2009-03-24
Release date:2009-07-21
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
J.Virol., 83, 2009
3OUO
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STRUCTURE OF THE NUCLEOPROTEIN FROM RIFT VALLEY FEVER VIRUS
Descriptor:Nucleoprotein, NITRITE ION
Authors:Ferron, F., Danek, E.I., Li, Z., Luo, D., Wong, Y.H., Coutard, B., Lantez, V., Charrel, R., Canard, B., Walz, T., Lescar, J.
Deposit date:2010-09-15
Release date:2011-05-25
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
3OV9
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STRUCTURE OF THE NUCLEOPROTEIN FROM RIFT VALLEY FEVER VIRUS
Descriptor:Nucleoprotein, NITRITE ION, SODIUM ION
Authors:Ferron, F., Danek, E.I., Li, Z., Luo, D., Wong, Y.H., Coutard, B., Lantez, V., Charrel, R., Canard, B., Walz, T., Lescar, J.
Deposit date:2010-09-16
Release date:2011-05-25
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011