Author results

1Q1M
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A HIGHLY EFFICIENT APPROACH TO A SELECTIVE AND CELL ACTIVE PTP1B INHIBITORS
分子名称:Protein-tyrosine phosphatase, non-receptor type 1, 5-{2-FLUORO-5-[3-(3-HYDROXY-2-METHOXYCARBONYL-PHENOXY)-PROPENYL]-PHENYL}-ISOXAZOLE-3-CARBOXYLIC ACID
著者Liu, G., Xin, Z., Pei, Z., Hajduk, P.J., Abad-Zapatero, C., Hutchins, C.W., Zhao, H., Lubben, T.H., Ballaron, S.J., Haasch, D.L., Kaszubska, W., Rondinone, C.M., Trevillyan, J.M., Jirousek, M.R.
登録日2003-07-22
公開日2003-09-16
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.
J.Med.Chem., 46, 2003
1PJW
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SOLUTION STRUCTURE OF THE DOMAIN III OF THE JAPAN ENCEPHALITIS VIRUS ENVELOPE PROTEIN
分子名称:envelope protein
著者Wu, K.P., Wu, C.W., Tsao, Y.P., Lou, Y.C., Lin, C.W.
登録日2003-06-04
公開日2003-11-25
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural Basis of a Flavivirus Recognized by Its Neutralizing Antibody: SOLUTION STRUCTURE OF THE DOMAIN III OF THE JAPANESE ENCEPHALITIS VIRUS ENVELOPE PROTEIN.
J.Biol.Chem., 278, 2003
2CPB
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SOLUTION NMR STRUCTURES OF THE MAJOR COAT PROTEIN OF FILAMENTOUS BACTERIOPHAGE M13 SOLUBILIZED IN DODECYLPHOSPHOCHOLINE MICELLES, 25 LOWEST ENERGY STRUCTURES
分子名称:M13 MAJOR COAT PROTEIN
著者Papavoine, C.H.M., Christiaans, B.E.C., Folmer, R.H.A., Konings, R.N.H., Hilbers, C.W.
登録日1998-04-16
公開日1998-11-11
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the M13 major coat protein in detergent micelles: a basis for a model of phage assembly involving specific residues.
J.Mol.Biol., 282, 1998
2CPS
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SOLUTION NMR STRUCTURES OF THE MAJOR COAT PROTEIN OF FILAMENTOUS BACTERIOPHAGE M13 SOLUBILIZED IN SODIUM DODECYL SULPHATE MICELLES, 25 LOWEST ENERGY STRUCTURES
分子名称:M13 MAJOR COAT PROTEIN
著者Papavoine, C.H.M., Christiaans, B.E.C., Folmer, R.H.A., Konings, R.N.H., Hilbers, C.W.
登録日1998-04-16
公開日1998-11-11
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the M13 major coat protein in detergent micelles: a basis for a model of phage assembly involving specific residues.
J.Mol.Biol., 282, 1998
2GVA
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REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE
分子名称:GENE V PROTEIN
著者Folkers, P.J.M., Nilges, M., Folmer, R.H.A., Prompers, J.J., Konings, R.N.H., Hilbers, C.W.
登録日1995-07-27
公開日1995-10-15
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Refined solution structure of the Tyr41-->His mutant of the M13 gene V protein. A comparison with the crystal structure.
Eur.J.Biochem., 232, 1995
2GVB
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REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE
分子名称:GENE V PROTEIN
著者Folkers, P.J.M., Nilges, M., Folmer, R.H.A., Prompers, J.J., Konings, R.N.H., Hilbers, C.W.
登録日1995-07-27
公開日1995-10-15
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Refined solution structure of the Tyr41-->His mutant of the M13 gene V protein. A comparison with the crystal structure.
Eur.J.Biochem., 232, 1995
1HIP
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TWO-ANGSTROM CRYSTAL STRUCTURE OF OXIDIZED CHROMATIUM HIGH POTENTIAL IRON PROTEIN
分子名称:HIGH POTENTIAL IRON PROTEIN, IRON/SULFUR CLUSTER
著者Carterjunior, C.W., Kraut, J., Freer, S.T., Xuong, N.-H., Alden, R.A., Bartsch, R.G.
登録日1975-04-01
公開日1976-11-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two-Angstrom crystal structure of oxidized Chromatium high potential iron protein.
J.Biol.Chem., 249, 1974
1A60
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NMR STRUCTURE OF A CLASSICAL PSEUDOKNOT: INTERPLAY OF SINGLE-AND DOUBLE-STRANDED RNA, 24 STRUCTURES
分子名称:TYMV PSEUDOKNOT
著者Kolk, M.H., Van Der Graaf, M., Wijmenga, S.S., Pleij, C.W.A., Heus, H.A., Hilbers, C.W.
登録日1998-03-04
公開日1998-05-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure of a classical pseudoknot: interplay of single- and double-stranded RNA.
Science, 280, 1998
1AKE
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STRUCTURE OF THE COMPLEX BETWEEN ADENYLATE KINASE FROM ESCHERICHIA COLI AND THE INHIBITOR AP5A REFINED AT 1.9 ANGSTROMS RESOLUTION: A MODEL FOR A CATALYTIC TRANSITION STATE
分子名称:ADENYLATE KINASE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE
著者Mueller, C.W., Schulz, G.E.
登録日1991-11-08
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap5A refined at 1.9 A resolution. A model for a catalytic transition state.
J.Mol.Biol., 224, 1992
1E4V
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MUTANT G10V OF ADENYLATE KINASE FROM E. COLI, MODIFIED IN THE GLY-LOOP
分子名称:Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE
著者Mueller, C.W., Schulz, G.E.
登録日2000-07-12
公開日2000-08-04
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of two mutants of adenylate kinase from Escherichia coli that modify the Gly-loop.
Proteins, 15, 1993
1E4Y
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MUTANT P9L OF ADENYLATE KINASE FROM E. COLI, MODIFIED IN THE GLY-LOOP
分子名称:Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE
著者Mueller, C.W., Schulz, G.E.
登録日2000-07-12
公開日2000-08-04
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of two mutants of adenylate kinase from Escherichia coli that modify the Gly-loop.
Proteins, 15, 1993
1ONY
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OXALYL-ARYL-AMINO BENZOIC ACID INHIBITORS OF PTP1B, COMPOUND 17
分子名称:Protein-tyrosine phosphatase, non-receptor type 1, 2-{[2-(2-CARBAMOYL-VINYL)-4-(2-METHANESULFONYLAMINO-2-PENTYLCARBAMOYL-ETHYL)-PHENYL]-OXALYL-AMINO}-BENZOIC ACID
著者Liu, G., Szczepankiewicz, B.G., Pei, Z., Janowich, D.A., Xin, Z., Hadjuk, P.J., Abad-Zapatero, C., Liang, H., Hutchins, C.W., Fesik, S.W., Ballaron, S.J., Stashko, M.A., Lubben, T., Mika, A.K., Zinker, B.A., Trevillyan, J.M., Jirousek, M.R.
登録日2003-03-02
公開日2003-05-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Discovery and Structure-Activity Relationship of Oxalylarylaminobenzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B
J.Med.Chem., 46, 2003
1ONZ
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OXALYL-ARYL-AMINO BENZOIC ACID INHIBITORS OF PTP1B, COMPOUND 8B
分子名称:Protein-tyrosine phosphatase, non-receptor type 1, 2-[(7-HYDROXY-NAPHTHALEN-1-YL)-OXALYL-AMINO]-BENZOIC ACID
著者Liu, G., Szczepankiewicz, B.G., Pei, Z., Janowich, D.A., Xin, Z., Hadjuk, P.J., Abad-Zapatero, C., Liang, H., Hutchins, C.W., Fesik, S.W., Ballaron, S.J., Stashko, M.A., Lubben, T., Mika, A.K., Zinker, B.A., Trevillyan, J.M., Jirousek, M.R.
登録日2003-03-02
公開日2003-05-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery and Structure-Activity Relationship of Oxalylarylaminobenzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B
J.Med.Chem., 46, 2003
3PHP
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STRUCTURE OF THE 3' HAIRPIN OF THE TYMV PSEUDOKNOT: PREFORMATION IN RNA FOLDING
分子名称:RNA (5'-R(*GP*GP*UP*UP*CP*CP*GP*AP*GP*GP*GP*UP*CP*AP*UP*CP*GP*GP*AP*AP*CP*CP*A) -3')
著者Kolk, M.H., Van Der Graaf, M., Wijmenga, S.S., Pleij, C.W.A., Heus, H.A., Hilbers, C.W.
登録日1998-10-13
公開日1998-10-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of the 3'-hairpin of the TYMV pseudoknot: preformation in RNA folding.
EMBO J., 17, 1998
4RNF
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PAMORA TANDEM DIGUANYLATE CYCLASE - MUTANT PHOSPHODIESTERASE, APO FORM
分子名称:Motility regulator
著者Phippen, C.W., Tews, I.
登録日2014-10-24
公開日2014-11-19
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
4RNH
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PAMORA TANDEM DIGUANYLATE CYCLASE - PHOSPHODIESTERASE, C-DI-GMP COMPLEX
分子名称:Motility regulator, MAGNESIUM ION, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
著者Phippen, C.W., Tews, I.
登録日2014-10-24
公開日2014-11-19
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
4RNI
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PAMORA DIMERIC PHOSPHODIESTERASE. APO FORM
分子名称:Motility regulator
著者Phippen, C.W., Tews, I.
登録日2014-10-24
公開日2014-11-19
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
4RNJ
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PAMORA PHOSPHODIESTERASE DOMAIN, APO FORM
分子名称:Motility regulator
著者Phippen, C.W., Tews, I.
登録日2014-10-24
公開日2014-11-19
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.
Febs Lett., 588, 2014
1A3Q
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HUMAN NF-KAPPA-B P52 BOUND TO DNA
分子名称:DNA (5'-D(*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*CP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B P52)
著者Cramer, P., Larson, C.J., Verdine, G.L., Muller, C.W.
登録日1998-01-23
公開日1998-06-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
EMBO J., 16, 1997
1D8A
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E. COLI ENOYL REDUCTASE/NAD+/TRICLOSAN COMPLEX
分子名称:ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN
著者Levy, C.W., Roujeinikova, A., Sedelnikova, S., Baker, P.J., Stuitje, A.R., Slabas, A.R., Rice, D.W., Rafferty, J.B.
登録日1999-10-21
公開日1999-10-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis of triclosan activity.
Nature, 398, 1999
1DKL
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI PHYTASE AT PH 4.5 (NO LIGAND BOUND)
分子名称:PHYTASE
著者Lim, D., Golovan, S., Forsberg, C.W., Jia, Z.
登録日1999-12-08
公開日2000-08-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
1DKM
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI PHYTASE AT PH 6.6 WITH HG2+ CATION ACTING AS AN INTERMOLECULAR BRIDGE
分子名称:PHYTASE, MERCURY (II) ION
著者Lim, D., Golovan, S., Forsberg, C.W., Jia, Z.
登録日1999-12-08
公開日2000-08-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
1DKN
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI PHYTASE AT PH 5.0 WITH HG2+ CATION ACTING AS AN INTERMOLECULAR BRIDGE
分子名称:PHYTASE, MERCURY (II) ION
著者Lim, D., Golovan, S., Forsberg, C.W., Jia, Z.
登録日1999-12-08
公開日2000-08-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
1DKO
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CRYSTAL STRUCTURE OF TUNGSTATE COMPLEX OF ESCHERICHIA COLI PHYTASE AT PH 6.6 WITH TUNGSTATE BOUND AT THE ACTIVE SITE AND WITH HG2+ CATION ACTING AS AN INTERMOLECULAR BRIDGE
分子名称:PHYTASE, MERCURY (II) ION, TUNGSTATE(VI)ION
著者Lim, D., Golovan, S., Forsberg, C.W., Jia, Z.
登録日1999-12-08
公開日2000-08-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
1DKP
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CRYSTAL STRUCTURE OF PHYTATE COMPLEX OF ESCHERICHIA COLI PHYTASE AT PH 6.6. PHYTATE IS BOUND WITH ITS 3-PHOSPHATE IN THE ACTIVE SITE. HG2+ CATION ACTS AS AN INTERMOLECULAR BRIDGE
分子名称:PHYTASE, MERCURY (II) ION, INOSITOL HEXAKISPHOSPHATE
著者Lim, D., Golovan, S., Forsberg, C.W., Jia, Z.
登録日1999-12-08
公開日2000-08-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000