Author results

3UTP
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1E6 TCR SPECIFIC FOR HLA-A*0201-ALWGPDPAAA
Descriptor:1E6 TCR alpha chain, 1E6 TCR beta chain, GLYCEROL, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.574 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTQ
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HUMAN HLA-A*0201-ALWGPDPAAA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTS
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1E6-A*0201-ALWGPDPAAA COMPLEX, MONOCLINIC
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTT
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1E6-A*0201-ALWGPDPAAA COMPLEX, TRICLINIC
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M., Rossjohn, J., Gras, S.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3O4L
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GENETIC AND STRUCTURAL BASIS FOR SELECTION OF A UBIQUITOUS T CELL RECEPTOR DEPLOYED IN EPSTEIN-BARR VIRUS
Descriptor:MHC class I antigen, Beta-2-microglobulin, BSLF2/BMLF1 protein, ...
Authors:Miles, J.J., Bulek, A.M., Cole, D.K., Gostick, E., Schauenburg, J.A., Dolton, G., Venturi, V., Davenport, M.P., Tan, M.P., Burrows, S.R., Wooldridge, L., Price, D.A., Rizkallah, P.J., Sewell, A.K.
Deposit date:2010-07-27
Release date:2011-01-12
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.
Plos Pathog., 6, 2010
5C07
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING YQFGPDFPIA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C08
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1E6 TCR IN COMPLEX WITH HLA-A0E CARRYING RQWGPDPAAV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C09
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HLA CLASS I HISTOCOMPATIBILITY ANTIGEN
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.475 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0A
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING MVW PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0B
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING RQFGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0C
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING RQFGPDWIVA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.974 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0D
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HLA-A02 CARRYING AQWGPDPAAA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0E
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HLA-A02 CARRYING YLGGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0F
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HLA-A02 CARRYING RQWGPDPAAV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.463 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0G
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HLA-A02 CARRYING YLGGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0I
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HAL-A02 CARRYING RQFGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0J
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HLA-A02 CARRYING RQFGPDWIVA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5N1Y
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HLA-A02 CARRYING MVWGPDPLYV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2017-02-06
Release date:2017-02-15
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J. Clin. Invest., 126, 2016
5N6B
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HUMAN LEUKOCYTE ANTIGEN CLASS I A02 CARRYING LLWNPGMAV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Bulek, A.M., Bovay, A.
Deposit date:2017-02-14
Release date:2017-10-18
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:T cell receptor alpha variable 12-2 bias in the immunodominant response to Yellow fever virus.
Eur. J. Immunol., 48, 2018
4I4W
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PEPTIDE LENGTH DETERMINES THE OUTCOME OF T CELL RECEPTOR/PEPTIDE-MHCI ENGAGEMENT
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Wooldridge, L., Cole, D.K.
Deposit date:2012-11-28
Release date:2013-01-02
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood, 121, 2013
4JFD
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PRESERVATION OF PEPTIDE SPECIFICITY DURING TCR-MHC CONTACT DOMINATED AFFINITY ENHANCEMENT OF A MELANOMA-SPECIFIC TCR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFE
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PRESERVATION OF PEPTIDE SPECIFICITY DURING TCR-MHC CONTACT DOMINATED AFFINITY ENHANCEMENT OF A MELANOMA-SPECIFIC TCR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFF
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PRESERVATION OF PEPTIDE SPECIFICITY DURING TCR-MHC CONTACT DOMINATED AFFINITY ENHANCEMENT OF A MELANOMA-SPECIFIC TCR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFH
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HIGH AFFINITY ALPHA24-BETA17 T CELL RECEPTOR FOR A2 HLA-MELANOMA PEPTIDE COMPLEX
Descriptor:alpha24 TCR allele, beta17 TCR allele, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFO
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A2 HLA COMPLEX WITH E1A HETEROCLITIC VARIANT OF MELANOMA PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K., Baker, B.M.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
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