Author results

1BBJ
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CRYSTAL STRUCTURE OF A CHIMERIC FAB' FRAGMENT OF AN ANTIBODY BINDING TUMOUR CELLS
Descriptor:IGG4-KAPPA B72.3 FAB (LIGHT CHAIN), IGG4-KAPPA B72.3 FAB (HEAVY CHAIN)
Authors:Brady, R.L., Hubbard, R.E., Todd, R.J.
Deposit date:1992-04-30
Release date:1994-01-31
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of a chimeric Fab' fragment of an antibody binding tumour cells.
J.Mol.Biol., 227, 1992
1CID
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CRYSTAL STRUCTURE OF DOMAINS 3 & 4 OF RAT CD4 AND THEIR RELATIONSHIP TO THE NH2-TERMINAL DOMAINS
Descriptor:T CELL SURFACE GLYCOPROTEIN CD4, SULFATE ION
Authors:Brady, R.L., Dodson, E.J., Lange, G.
Deposit date:1993-01-28
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains.
Science, 260, 1993
1HCF
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CRYSTAL STRUCTURE OF TRKB-D5 BOUND TO NEUROTROPHIN-4/5
Descriptor:NEUROTROPHIN-4, BDNF/NT-3 GROWTH FACTORS RECEPTOR, SULFATE ION
Authors:Banfield, M.J., Naylor, R.L., Robertson, A.G.S., Allen, S.J., Dawbarn, D., Brady, R.L.
Deposit date:2001-05-03
Release date:2001-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Specificity in Trk-Receptor:Neurotrophin Interaction: The Crystal Structure of Trkb-D5 in Complex with Neurotrophin-4/5
Structure, 9, 2001
1CEQ
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CHLOROQUINE BINDS IN THE COFACTOR BINDING SITE OF PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE.
Descriptor:PROTEIN (L-LACTATE DEHYDROGENASE)
Authors:Read, J.A., Wilkinson, K.W., Tranter, R., Sessions, R.B., Brady, R.L.
Deposit date:1999-03-10
Release date:1999-03-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Chloroquine binds in the cofactor binding site of Plasmodium falciparum lactate dehydrogenase.
J.Biol.Chem., 274, 1999
1CET
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CHLOROQUINE BINDS IN THE COFACTOR BINDING SITE OF PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE.
Descriptor:PROTEIN (L-LACTATE DEHYDROGENASE), N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE
Authors:Read, J.A., Wilkinson, K.W., Tranter, R., Sessions, R.B., Brady, R.L.
Deposit date:1999-03-10
Release date:1999-03-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Chloroquine binds in the cofactor binding site of Plasmodium falciparum lactate dehydrogenase.
J.Biol.Chem., 274, 1999
1CLO
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ANTI-CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY A5B7
Descriptor:A5B7 MONOCLONAL ANTIBODY
Authors:Banfield, M.J., King, D.J., Mountain, A., Brady, R.L.
Deposit date:1996-05-01
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs.
Proteins, 29, 1997
1QOU
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CEN (CENTRORADIALIS) PROTEIN FROM ANTIRRHINUM
Descriptor:CEN
Authors:Banfield, M.J., Brady, R.L.
Deposit date:1999-11-17
Release date:2000-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure of Antirrhinum Centroradialis Protein (Cen) Suggests a Role as a Kinase Regulator
J.Mol.Biol., 297, 2000
1A64
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ENGINEERING A MISFOLDED FORM OF RAT CD2
Descriptor:CD2
Authors:Murray, A.J., Head, J.G., Barker, J.J., Brady, R.L.
Deposit date:1998-03-05
Release date:1998-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Engineering an intertwined form of CD2 for stability and assembly.
Nat.Struct.Biol., 5, 1998
1A6P
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ENGINEERING OF A MISFOLDED FORM OF CD2
Descriptor:T-CELL SURFACE ANTIGEN CD2
Authors:Murray, A.J., Head, J.G., Barker, J.J., Brady, R.L.
Deposit date:1998-02-26
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Engineering an intertwined form of CD2 for stability and assembly.
Nat.Struct.Biol., 5, 1998
1A7B
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ENGINEERING A MISFOLDED FORM OF CD2
Descriptor:CD2
Authors:Murray, A.J., Head, J.G., Barker, J.J., Brady, R.L.
Deposit date:1998-03-10
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Engineering an intertwined form of CD2 for stability and assembly.
Nat.Struct.Biol., 5, 1998
1AD0
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FAB FRAGMENT OF ENGINEERED HUMAN MONOCLONAL ANTIBODY A5B7
Descriptor:ANTIBODY A5B7 (LIGHT CHAIN), ANTIBODY A5B7 (HEAVY CHAIN)
Authors:Banfield, M.J., Brady, R.L.
Deposit date:1997-02-19
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs.
Proteins, 29, 1997
1AD9
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IGG-FAB FRAGMENT OF ENGINEERED HUMAN MONOCLONAL ANTIBODY CTM01
Descriptor:IGG CTM01 FAB (LIGHT CHAIN), IGG CTM01 FAB (HEAVY CHAIN), SULFATE ION
Authors:Banfield, M.J., Brady, R.L.
Deposit date:1997-02-24
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs.
Proteins, 29, 1997
1AE6
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IGG-FAB FRAGMENT OF MOUSE MONOCLONAL ANTIBODY CTM01
Descriptor:IGG CTM01 FAB (LIGHT CHAIN), IGG CTM01 FAB (HEAVY CHAIN)
Authors:Banfield, M.J., Brady, R.L.
Deposit date:1997-03-06
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs.
Proteins, 29, 1997
1B94
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RESTRICTION ENDONUCLEASE ECORV WITH CALCIUM
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV, CALCIUM ION
Authors:Thomas, M.P., Halford, S.E., Brady, R.L.
Deposit date:1999-02-19
Release date:1999-02-26
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group.
Nucleic Acids Res., 27, 1999
1B95
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ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV
Authors:Thomas, M.P., Halford, S.E., Brady, R.L.
Deposit date:1999-02-19
Release date:1999-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group.
Nucleic Acids Res., 27, 1999
1B96
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ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV
Authors:Thomas, M.P., Halford, S.E., Brady, R.L.
Deposit date:1999-02-19
Release date:1999-02-26
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group.
Nucleic Acids Res., 27, 1999
1B97
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ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP
Descriptor:DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV
Authors:Thomas, M.P., Halford, S.E., Brady, R.L.
Deposit date:1999-02-19
Release date:1999-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group.
Nucleic Acids Res., 27, 1999
1BD9
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HUMAN PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN
Descriptor:PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN
Authors:Banfield, M.J., Barker, J.J., Perry, A.C.F., Brady, R.L.
Deposit date:1998-05-12
Release date:1998-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction.
Structure, 6, 1998
1BEH
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HUMAN PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN IN COMPLEX WITH CACODYLATE
Descriptor:PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN, CACODYLATE ION
Authors:Banfield, M.J., Barker, J.J., Perry, A., Brady, R.L.
Deposit date:1998-05-14
Release date:1998-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction.
Structure, 6, 1998
1CDC
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CD2, N-TERMINAL DOMAIN (1-99), TRUNCATED FORM
Descriptor:CD2
Authors:Murray, A.J., Barclay, A.N., Brady, R.L.
Deposit date:1995-05-23
Release date:1995-09-15
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:One sequence, two folds: a metastable structure of CD2.
Proc.Natl.Acad.Sci.USA, 92, 1995
1E3S
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RAT BRAIN 3-HYDROXYACYL-COA DEHYDROGENASE BINARY COMPLEX WITH NADH
Descriptor:SHORT CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Powell, A.J., Read, J.A., Banfield, M.J., Brady, R.L.
Deposit date:2000-06-22
Release date:2001-05-25
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of Structurally Diverse Substrates by Type II 3-Hydroxyacyl-Coa Dehydrogenase (Hadh II) Amyloid-Beta Binding Alcohol Dehydrogenase (Abad)
J.Mol.Biol., 303, 2000
1E3W
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RAT BRAIN 3-HYDROXYACYL-COA DEHYDROGENASE BINARY COMPLEX WITH NADH AND 3-KETO BUTYRATE
Descriptor:SHORT CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Powell, A.J., Read, J.A., Brady, R.L.
Deposit date:2000-06-26
Release date:2001-05-25
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of Structurally Diverse Substrates by Type II 3-Hydroxyacyl-Coa Dehydrogenase (Hadh II) Amyloid-Beta Binding Alcohol Dehydrogenase (Abad)
J.Mol.Biol., 303, 2000
1E6W
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RAT BRAIN 3-HYDROXYACYL-COA DEHYDROGENASE BINARY COMPLEX WITH NADH AND ESTRADIOL
Descriptor:SHORT CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ESTRADIOL
Authors:Read, J.A., Powell, A.J., Brady, R.L.
Deposit date:2000-08-23
Release date:2001-05-25
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Recognition of Structurally Diverse Substrates by Type II 3-Hydroxyacyl-Coa Dehydrogenase (Hadh II) Amyloid-Beta Binding Alcohol Dehydrogenase (Abad)
J.Mol.Biol., 303, 2000
1EB2
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TRYPSIN INHIBITOR COMPLEX (BPO)
Descriptor:TRYPSIN, SULFATE ION, CALCIUM ION, ...
Authors:Wilkinson, K.W., Young, S.C., Liebeschuetz, J.W., Brady, R.L.
Deposit date:2001-07-18
Release date:2002-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pro_Select: Combining Structure-Based Drug Design and Array-Based Chemistry for Rapid Lead Discovery. 2. The Development of a Series of Highly Potent and Selective Factor Xa Inhibitors
J.Med.Chem., 45, 2002
1FIW
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THREE-DIMENSIONAL STRUCTURE OF BETA-ACROSIN FROM RAM SPERMATOZOA
Descriptor:BETA-ACROSIN HEAVY CHAIN, BETA-ACROSIN LIGHT CHAIN, BETA-L-FUCOSE, ...
Authors:Tranter, R., Read, J.A., Jones, R., Brady, R.L.
Deposit date:2000-08-07
Release date:2000-11-08
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Effector sites in the three-dimensional structure of mammalian sperm beta-acrosin.
Structure Fold.Des., 8, 2000