Author results

1HMC
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THREE-DIMENSIONAL STRUCTURE OF DIMERIC HUMAN RECOMBINANT MACROPHAGE COLONY STIMULATING FACTOR
Descriptor:HUMAN MACROPHAGE COLONY STIMULATING FACTOR
Authors:Bohm, A., Pandit, J., Jancarik, J., Halenbeck, R., Koths, K., Kim, S.-H.
Deposit date:1993-12-22
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor.
Science, 258, 1992
1GOT
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HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS
Descriptor:GT-ALPHA/GI-ALPHA CHIMERA, GT-BETA, GT-GAMMA, ...
Authors:Lambright, D.G., Sondek, J., Bohm, A., Skiba, N.P., Hamm, H.E., Sigler, P.B.
Deposit date:1996-08-07
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 A crystal structure of a heterotrimeric G protein.
Nature, 379, 1996
1TBG
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BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN
Descriptor:TRANSDUCIN
Authors:Sondek, J.S., Bohm, A., Lambright, D.G., Hamm, H.E., Sigler, P.B.
Deposit date:1996-06-15
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
Nature, 379, 1996
2TRC
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PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX
Descriptor:TRANSDUCIN, PHOSDUCIN, GADOLINIUM ATOM
Authors:Gaudet, R., Bohm, A., Sigler, P.B.
Deposit date:1997-01-06
Release date:1997-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
1A0R
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HETEROTRIMERIC COMPLEX OF PHOSDUCIN/TRANSDUCIN BETA-GAMMA
Descriptor:TRANSDUCIN (BETA SUBUNIT), TRANSDUCIN (GAMMA SUBUNIT), PHOSDUCIN, ...
Authors:Loew, A., Ho, Y.-K., Blundell, T.L., Bax, B.
Deposit date:1997-12-05
Release date:1998-12-30
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phosducin induces a structural change in transducin beta gamma.
Structure, 6, 1998
1B9X
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STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN
Descriptor:PROTEIN (TRANSDUCIN), PROTEIN (PHOSDUCIN), GADOLINIUM ATOM
Authors:Gaudet, R., Sigler, P.B.
Deposit date:1999-02-16
Release date:1999-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1B9Y
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STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN BETA-GAMMA
Descriptor:PROTEIN (TRANSDUCIN), PROTEIN (PHOSDUCIN), GADOLINIUM ATOM
Authors:Gaudet, R., Sigler, P.B.
Deposit date:1999-02-16
Release date:1999-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1FA0
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STRUCTURE OF YEAST POLY(A) POLYMERASE BOUND TO MANGANATE AND 3'-DATP
Descriptor:POLY(A)-POLYMERASE, MANGANESE (II) ION, 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Bard, J., Zhelkovsky, A.M., Helmling, S., Moore, C.L., Bohm, A.
Deposit date:2000-07-11
Release date:2000-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of yeast poly(A) polymerase alone and in complex with 3'-dATP.
Science, 289, 2000
1K8T
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF)
Descriptor:CALMODULIN-SENSITIVE ADENYLATE CYCLASE, SULFATE ION, NICKEL (II) ION
Authors:Drum, C.L., Yan, S.-Z., Bard, J., Shen, Y.-Q., Lu, D., Soelaiman, S., Grabarek, Z., Bohm, A., Tang, W.-J.
Deposit date:2001-10-25
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin
Nature, 415, 2002
1K90
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND 3' DEOXY-ATP
Descriptor:CALMODULIN-SENSITIVE ADENYLATE CYCLASE, CALMODULIN, YTTERBIUM (III) ION, ...
Authors:Drum, C.L., Yan, S.-Z., Bard, J., Shen, Y.-Q., Lu, D., Soelaiman, S., Grabarek, Z., Bohm, A., Tang, W.-J.
Deposit date:2001-10-26
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Nature, 415, 2002
1K93
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN
Descriptor:CALMODULIN-SENSITIVE ADENYLATE CYCLASE, CALMODULIN, SULFATE ION, ...
Authors:Drum, C.L., Yan, S.-Z., Bard, J., Shen, Y.-Q., Lu, D., Soelaiman, S., Grabarek, Z., Bohm, A., Tang, W.-J.
Deposit date:2001-10-26
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Nature, 415, 2002
1LVC
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CRYSTAL STRUCTURE OF THE ADENYLYL CYCLASE DOMAIN OF ANTHRAX EDEMA FACTOR (EF) IN COMPLEX WITH CALMODULIN AND 2' DEOXY, 3' ANTHRANILOYL ATP
Descriptor:calmodulin-sensitive adenylate cyclase, calmodulin, YTTERBIUM (III) ION, ...
Authors:Shen, Y., Lee, Y.-S., Soelaiman, S., Bergson, P., Lu, D., Chen, A., Beckingham, K., Grabarek, Z., Mrksich, M., Tang, W.-J.
Deposit date:2002-05-28
Release date:2002-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins
Embo J., 21, 2002
1S26
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STRUCTURE OF ANTHRAX EDEMA FACTOR-CALMODULIN-ALPHA,BETA-METHYLENEADENOSINE 5'-TRIPHOSPHATE COMPLEX REVEALS AN ALTERNATIVE MODE OF ATP BINDING TO THE CATALYTIC SITE
Descriptor:Calmodulin-sensitive adenylate cyclase, Calmodulin, YTTERBIUM (III) ION, ...
Authors:Shen, Y., Zhukovskaya, N.L., Bohm, A., Tang, W.-J.
Deposit date:2004-01-08
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of anthrax edema factor-calmodulin-adenosine-5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site
Biochem.Biophys.Res.Commun., 317, 2004
2FUF
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CRYSTAL STRUCTURE OF THE SV40 LARGE T ANTIGEN ORIGIN-BINDING DOMAIN
Descriptor:Large T antigen, CITRATE ANION
Authors:Meinke, G., Bullock, P.A., Bohm, A.
Deposit date:2006-01-26
Release date:2006-08-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of the simian virus 40 large T-antigen origin-binding domain.
J.Virol., 80, 2006
2HHP
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STRUCTURE OF YEAST POLY(A) POLYMERASE IN A CLOSED CONFORMATION.
Descriptor:Poly(A) polymerase, CITRATE ANION, MAGNESIUM ION
Authors:Bohm, A., Toth, J.
Deposit date:2006-06-28
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
2O1P
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STRUCTURE OF YEAST POLY(A) POLYMERASE IN A SOMEWHAT CLOSED STATE
Descriptor:Poly(A) polymerase
Authors:Bohm, A., Balbo, P., Toth, J.
Deposit date:2006-11-29
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
2IF9
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CRYSTAL STRUCTURE OF SV40 T-ANTIGEN ORIGIN BINDING DOMAIN DISULFIDE-LINKED DIMER
Descriptor:Large T antigen
Authors:Meinke, G., Bullock, P.A., Bohm, A.
Deposit date:2006-09-20
Release date:2007-02-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA
Plos Biol., 5, 2007
2NTC
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CRYSTAL STRUCTURE OF SV40 LARGE T ANTIGEN ORIGIN BINDING DOMAIN WITH DNA
Descriptor:21-nt PEN element of the SV40 DNA origin, large T antigen
Authors:Bohm, A., Meinke, G., Bullock, P.A.
Deposit date:2006-11-07
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA
Plos Biol., 5, 2007
2Q66
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STRUCTURE OF YEAST POLY(A) POLYMERASE WITH ATP AND OLIGO(A)
Descriptor:5'-R(P*AP*AP*AP*AP*A)-3', Poly(A) polymerase, 1,2-ETHANEDIOL, ...
Authors:Bohm, A., Balbo, P.
Deposit date:2007-06-04
Release date:2007-08-28
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of poly(A) polymerase: structure of the enzyme-MgATP-RNA ternary complex and kinetic analysis.
Structure, 15, 2007
3BJ9
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CRYSTAL STRUCTURE OF THE SURROGATE LIGHT CHAIN VARIABLE DOMAIN VPREBJ
Descriptor:Immunoglobulin iota chain, Immunoglobulin lambda-like polypeptide 1, 1,2-ETHANEDIOL
Authors:Morstadt, L.M., Bohm, A.A., Stollar, B.D., Baleja, J.D.
Deposit date:2007-12-03
Release date:2008-03-04
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Engineering and characterization of a single chain surrogate light chain variable domain.
Protein Sci., 17, 2008
3C66
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YEAST POLY(A) POLYMERASE IN COMPLEX WITH FIP1 RESIDUES 80-105
Descriptor:Poly(A) polymerase, Pre-mRNA polyadenylation factor FIP1, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Bohm, A., Meinke, G.
Deposit date:2008-02-02
Release date:2008-05-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein.
Biochemistry, 47, 2008
3QK2
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STRUCTURE-BASED ANALYSIS OF THE INTERACTION BETWEEN THE SIMIAN VIRUS 40 T-ANTIGEN ORIGIN BINDING DOMAIN AND SINGLE-STRANDED DNA
Descriptor:Large T antigen, THIOCYANATE ION
Authors:Meinke, G., Bullock, P.A., Bohm, A.
Deposit date:2011-01-31
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.643 Å)
Cite:Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA.
J.Virol., 85, 2011
3MI7
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AN ENHANCED REPRESSOR OF HUMAN PAPILLOMAVIRUS E2 PROTEIN
Descriptor:Regulatory protein E2, 1,2-ETHANEDIOL
Authors:Bohm, A., Baleja, J., Bose, K., Meinke, G.
Deposit date:2010-04-09
Release date:2011-04-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Design and characterization of an enhanced repressor of human papillomavirus E2 protein.
Faseb J., 25, 2011
3QFQ
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ASYMMETRIC ASSEMBLY OF MERKEL CELL POLYOMAVIRUS LARGE T-ANTIGEN ORIGIN BINDING DOMAINS AT THE VIRAL ORIGIN
Descriptor:Large T antigen, DNA (26-MER)
Authors:Harrison, C.J., Meinke, G., Bohm, A.
Deposit date:2011-01-22
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9001 Å)
Cite:Asymmetric assembly of merkel cell polyomavirus large T-antigen origin binding domains at the viral origin.
J.Mol.Biol., 409, 2011
3QGJ
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1.3A STRUCTURE OF ALPHA-LYTIC PROTEASE BOUND TO AC-ALAALAPRO-ALANAL
Descriptor:Alpha-lytic protease, Ac-AlaAlaPro-Alanal peptide, 1,2-ETHANEDIOL, ...
Authors:Everill, P., Meinke, G., Bohm, A., Bachovchin, W.
Deposit date:2011-01-24
Release date:2012-02-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Substrate Binding Defines Ser195 Position in the Catalytic Triad of Serine Proteases, Not His57 protonation
To be Published
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