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7B3K
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Dynamic complex between all-D-enantiomeric peptide D3 with L723P mutant of amyloid precursor protein (APP) 672-726 fragment (amyloid beta 1-55)
Descriptor: D3 all D-enantimeric peptide, Isoform L-APP677 of Amyloid-beta precursor protein
Authors:Bocharov, E.V, Volynsky, P.E, Okhrimenko, I.S, Urban, A.S.
Deposit date:2020-12-01
Release date:2021-01-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:All - d - Enantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-beta Precursors.
J.Med.Chem., 64, 2021
7B3J
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Dynamic complex between all-D-enantiomeric peptide D3 with wild-type amyloid precursor protein 672-726 fragment (amyloid beta 1-55)
Descriptor: D3 all D-enantimeric peptide, Isoform L-APP677 of Amyloid-beta precursor protein
Authors:Bocharov, E.V, Volynsky, P.E, Okhrimenko, I.S, Urban, A.S.
Deposit date:2020-12-01
Release date:2021-01-13
Last modified:2021-12-08
Method:SOLUTION NMR
Cite:All - d - Enantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-beta Precursors.
J.Med.Chem., 64, 2021
1RQU
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BU of 1rqu by Molmil
NMR structure of L7 dimer from E.coli
Descriptor: 50S ribosomal protein L7/L12
Authors:Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
Deposit date:2003-12-07
Release date:2004-03-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:From structure and dynamics of protein L7/L12 to molecular switching in ribosome.
J.Biol.Chem., 279, 2004
1RQS
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NMR structure of C-terminal domain of ribosomal protein L7 from E.coli
Descriptor: 50S ribosomal protein L7/L12
Authors:Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
Deposit date:2003-12-07
Release date:2004-03-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:From structure and dynamics of protein L7/L12 to molecular switching in ribosome.
J.Biol.Chem., 279, 2004
1RQT
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NMR structure of dimeric N-terminal domain of ribosomal protein L7 from E.coli
Descriptor: 50S ribosomal protein L7/L12
Authors:Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
Deposit date:2003-12-07
Release date:2004-03-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:From structure and dynamics of protein L7/L12 to molecular switching in ribosome.
J.Biol.Chem., 279, 2004
1RQV
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Spatial model of L7 dimer from E.coli with one hinge region in helical state
Descriptor: 50S ribosomal protein L7/L12
Authors:Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
Deposit date:2003-12-07
Release date:2004-03-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:From structure and dynamics of protein L7/L12 to molecular switching in ribosome
J.Biol.Chem., 279, 2004
2J5D
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BU of 2j5d by Molmil
NMR structure of BNIP3 transmembrane domain in lipid bicelles
Descriptor: BCL2/ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3
Authors:Bocharov, E.V, Pustovalova, Y.E, Volynsky, P.E, Maslennikov, I.V, Goncharuk, M.V, Ermolyuk, Y.S, Arseniev, A.S.
Deposit date:2006-09-14
Release date:2007-04-17
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Unique dimeric structure of BNip3 transmembrane domain suggests membrane permeabilization as a cell death trigger.
J. Biol. Chem., 282, 2007
5OEK
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Putative active dimeric state of GHR transmembrane domain
Descriptor: Growth hormone receptor
Authors:Lesovoy, D.M, Bocharov, E.V, Bocharova, O.V, Urban, A.S, Arseniev, A.S.
Deposit date:2017-07-08
Release date:2018-04-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of the signal transduction via transmembrane domain of the human growth hormone receptor.
Biochim. Biophys. Acta, 1862, 2018
5OHD
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Putative inactive (dormant) dimeric state of GHR transmembrane domain
Descriptor: Growth hormone receptor
Authors:Lesovoy, D.M, Bocharov, E.V, Bocharova, O.V, Urban, A.S, Arseniev, A.S.
Deposit date:2017-07-15
Release date:2018-04-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of the signal transduction via transmembrane domain of the human growth hormone receptor.
Biochim. Biophys. Acta, 1862, 2018
2K1K
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NMR structures of dimeric transmembrane domain of the receptor tyrosine kinase EphA1 in lipid bicelles at pH 4.3
Descriptor: Ephrin type-A receptor 1
Authors:Mayzel, M.L, Bocharov, E.V, Arseniev, A.S, Goncharuk, M.V.
Deposit date:2008-03-06
Release date:2008-09-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Spatial Structure and pH-dependent Conformational Diversity of Dimeric Transmembrane Domain of the Receptor Tyrosine Kinase EphA1
J.Biol.Chem., 283, 2008
2K1L
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NMR structures of dimeric transmembrane domain of the receptor tyrosine kinase EphA1 in lipid bicelles at pH 6.3
Descriptor: Ephrin type-A receptor 1
Authors:Mayzel, M.L, Bocharov, E.V, Arseniev, A.S, Goncharuk, M.V.
Deposit date:2008-03-07
Release date:2008-09-09
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Spatial Structure and pH-dependent Conformational Diversity of Dimeric Transmembrane Domain of the Receptor Tyrosine Kinase EphA1.
J.Biol.Chem., 283, 2008
2JWA
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ErbB2 transmembrane segment dimer spatial structure
Descriptor: Receptor tyrosine-protein kinase erbB-2
Authors:Mineev, K.S, Bocharov, E.V, Arseniev, A.S.
Deposit date:2007-10-09
Release date:2008-01-22
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Spatial Structure of the Dimeric Transmembrane Domain of the Growth Factor Receptor ErbB2 Presumably Corresponding to the Receptor Active State
J.Biol.Chem., 283, 2008
2K9Y
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EphA2 dimeric structure in the lipidic bicelle at pH 5.0
Descriptor: Ephrin type-A receptor 2
Authors:Mayzel, M.L, Bocharov, E.V, Volynsky, P.E, Arseniev, A.S.
Deposit date:2008-10-27
Release date:2009-08-11
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Left-Handed Dimer of EphA2 Transmembrane Domain: Helix Packing Diversity among Receptor Tyrosine Kinases
Biophys.J., 98, 2010
2LCX
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BU of 2lcx by Molmil
Spatial Structure of the ErbB4 dimeric TM domain
Descriptor: Receptor tyrosine-protein kinase erbB-4
Authors:Mineev, K.S, Bocharov, E.V, Arseniev, A.S.
Deposit date:2011-05-11
Release date:2012-05-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and thermodynamic insight into the process of "weak" dimerization of the ErbB4 transmembrane domain by solution NMR.
Biochim.Biophys.Acta, 1818, 2012
2L2T
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BU of 2l2t by Molmil
Solution NMR structure of the ErbB4 dimeric membrane domain
Descriptor: Receptor tyrosine-protein kinase erbB-4
Authors:Mineev, K.S, Bocharov, E.V, Goncharuk, M.V, Arseniev, A.S.
Deposit date:2010-08-27
Release date:2011-09-14
Last modified:2017-09-06
Method:SOLUTION NMR
Cite:Structural and thermodynamic insight into the process of "weak" dimerization of the ErbB4 transmembrane domain by solution NMR.
Biochim. Biophys. Acta, 1818, 2012
2M0B
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Homodimeric transmembrane domain of the human receptor tyrosine kinase ErbB1 (EGFR, HER1) in micelles
Descriptor: Epidermal growth factor receptor
Authors:Lesovoy, D.M, Bocharov, E.V, Pustovalova, Y.E, Bocharova, O.V, Arseniev, A.S.
Deposit date:2012-10-24
Release date:2013-10-30
Last modified:2019-06-26
Method:SOLUTION NMR
Cite:Alternative packing of EGFR transmembrane domain suggests that protein-lipid interactions underlie signal conduction across membrane.
Biochim. Biophys. Acta, 1858, 2016
2LZL
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BU of 2lzl by Molmil
FGFR3tm
Descriptor: Fibroblast growth factor receptor 3
Authors:Lesovoy, D.M, Bocharov, E.V, Goncharuk, S.A, Arseniev, A.S.
Deposit date:2012-10-04
Release date:2013-10-09
Last modified:2013-11-27
Method:SOLUTION NMR
Cite:Structure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human Pathologies.
Structure, 21, 2013
7O9U
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BU of 7o9u by Molmil
Solution structure of oxidized cytochrome c552 from Thioalkalivibrio paradoxus
Descriptor: Cytochrome c552, HEME C
Authors:Britikov, V.V, Britikova, E.V, Altukhov, D.A, Timofeev, V.I, Dergousova, N.I, Rakitina, T.V, Tikhonova, T.V, Usanov, S.A, Popov, V.O, Bocharov, E.V.
Deposit date:2021-04-17
Release date:2021-05-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Unusual Cytochrome c 552 from Thioalkalivibrio paradoxus : Solution NMR Structure and Interaction with Thiocyanate Dehydrogenase.
Int J Mol Sci, 23, 2022
1J5J
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BU of 1j5j by Molmil
Solution structure of HERG-specific scorpion toxin BeKm-1
Descriptor: BeKm-1 toxin
Authors:Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V.
Deposit date:2002-04-16
Release date:2002-11-20
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
J.Biol.Chem., 277, 2002
1LGL
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Solution structure of HERG-specific scorpion toxin BeKm-1
Descriptor: BeKm-1 toxin
Authors:Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V.
Deposit date:2002-04-16
Release date:2002-11-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
J.Biol.Chem., 277, 2002
1FFJ
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BU of 1ffj by Molmil
NMR STRUCTURE OF CARDIOTOXIN IN DPC-MICELLE
Descriptor: CYTOTOXIN 2
Authors:Dubovskii, P.V, Dementieva, D.V, Bocharov, E.V, Utkin, Y.N, Arseniev, A.S.
Deposit date:2000-07-25
Release date:2001-01-17
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Membrane binding motif of the P-type cardiotoxin.
J.Mol.Biol., 305, 2001
6Z1Y
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Crystal structure of type-I ribosome-inactivating protein trichobakin (TBK)
Descriptor: SODIUM ION, Trichobakin
Authors:Boyko, K.M, Nikolaeva, A.Y, Britikov, V.V, Bocharov, E.V, Britikova, E.V, Le, T.B.T, Phan, C.V, Popov, V.O, Usanov, S.A.
Deposit date:2020-05-14
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of type-I ribosome-inactivating protein trichobakin (TBK)
To Be Published
6YTS
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BU of 6yts by Molmil
Solution NMR structure of type-I ribosome-inactivating protein trichobakin (TBK)
Descriptor: Trichobakin
Authors:Britikov, V.V, Bocharov, E.V, Britikova, E.V, Le, T.B.T, Phan, C.V, Boyko, K.M, Arseniev, A.S, Usanov, S.A.
Deposit date:2020-04-24
Release date:2020-05-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure and dynamics of type-I ribosome-inactivating protein trichobakin (TBK)
To Be Published
1CCQ
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NMR STRUCTURE WITH TIGHTLY BOUND WATER MOLECULES OF CYTOTOXIN II (CARDIOTOXIN) FROM NAJA NAJA OXIANA IN AQUEOUS SOLUTION (MINOR FORM).
Descriptor: PROTEIN (CYTOTOXIN 2)
Authors:Dementieva, D.V, Bocharov, E.V, Arseniev, A.S.
Deposit date:1999-03-02
Release date:1999-06-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Two forms of cytotoxin II (cardiotoxin) from Naja naja oxiana in aqueous solution: spatial structures with tightly bound water molecules.
Eur.J.Biochem., 263, 1999
1CB9
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NMR STRUCTURE WITH TIGHTLY BOUND WATER MOLECULES OF CYTOTOXIN II (CARDIOTOXIN) FROM NAJA NAJA OXIANA IN AQUEOUS SOLUTION (MAJOR FORM).
Descriptor: PROTEIN (CYTOTOXIN 2)
Authors:Dementieva, D.V, Bocharov, E.V, Arseniev, A.S.
Deposit date:1999-03-01
Release date:1999-06-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Two forms of cytotoxin II (cardiotoxin) from Naja naja oxiana in aqueous solution: spatial structures with tightly bound water molecules.
Eur.J.Biochem., 263, 1999

 

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