4WIP
 
 | | DIX domain of human Dvl2 | | Descriptor: | PENTAETHYLENE GLYCOL, Segment polarity protein dishevelled homolog DVL-2 | | Authors: | Fiedler, M, Bienz, M, Madrzak, J, Chin, J.W. | | Deposit date: | 2014-09-26 | | Release date: | 2015-05-13 | | Method: | X-RAY DIFFRACTION (2.691 Å) | | Cite: | Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.
Nat Commun, 6, 2015
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4UP5
 | | Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment | | Descriptor: | 6-methoxy-1,3-benzothiazol-2-amine, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ... | | Authors: | Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M. | | Deposit date: | 2014-06-12 | | Release date: | 2014-11-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
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4UP0
 | | Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide | | Descriptor: | HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ... | | Authors: | Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M. | | Deposit date: | 2014-06-11 | | Release date: | 2014-11-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
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5LNP
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2VPE
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ... | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | Deposit date: | 2008-02-27 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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5SUY
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5SUZ
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6RSN
 | | SOSEKI polymerising domain (SOK4 D85A mutant) | | Descriptor: | SULFATE ION, UPSTREAM OF FLC-like protein (DUF966) | | Authors: | Fiedler, M, Bienz, M. | | Deposit date: | 2019-05-21 | | Release date: | 2020-01-29 | | Last modified: | 2020-02-19 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | DIX Domain Polymerization Drives Assembly of Plant Cell Polarity Complexes.
Cell, 180, 2020
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7QCE
 | | Crystal structure of an atypical PHD finger of VIN3 | | Descriptor: | DI(HYDROXYETHYL)ETHER, VIN3 (Protein VERNALIZATION INSENSITIVE 3), ZINC ION | | Authors: | Franco-Echevarria, E, Fiedler, M, Dean, C, Bienz, M. | | Deposit date: | 2021-11-23 | | Release date: | 2022-11-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.
J.Biol.Chem., 298, 2022
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6S9R
 | | Crystal structure of SSDP from D. melanogaster | | Descriptor: | Sequence-specific single-stranded DNA-binding protein, isoform A | | Authors: | Renko, M, Bienz, M. | | Deposit date: | 2019-07-15 | | Release date: | 2019-10-09 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6S9T
 | | Dimerization domain of Xenopus laevis LDB1 in complex with darpin 3 | | Descriptor: | Darpin 3, LIM domain-binding protein 1, TETRAETHYLENE GLYCOL | | Authors: | Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M. | | Deposit date: | 2019-07-15 | | Release date: | 2019-10-09 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6S9S
 | | Dimerization domain of Xenopus laevis LDB1 in complex with darpin 10 | | Descriptor: | Darpin 10, LIM domain-binding protein 1 | | Authors: | Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M. | | Deposit date: | 2019-07-15 | | Release date: | 2019-10-09 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7O6W
 | | Crystal structure of (the) VEL1 VEL polymerising domain (I664D mutant) | | Descriptor: | PHOSPHATE ION, VIN3-like protein 2 | | Authors: | Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M. | | Deposit date: | 2021-04-12 | | Release date: | 2022-11-09 | | Last modified: | 2022-11-23 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
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7O6T
 | | Crystal structure of the polymerising VEL domain of VIN3 (R556D I575D mutant) | | Descriptor: | MAGNESIUM ION, Protein VERNALIZATION INSENSITIVE 3 | | Authors: | Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M. | | Deposit date: | 2021-04-12 | | Release date: | 2022-11-09 | | Last modified: | 2022-11-23 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
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7O6V
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7O6U
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7OQV
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2VP7
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SULFATE ION, ... | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | Deposit date: | 2008-02-26 | | Release date: | 2008-06-17 | | Last modified: | 2019-05-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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2VPG
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ... | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Bienz, M, Evans, P. | | Deposit date: | 2008-02-27 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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2VPD
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, ZINC ION | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | Deposit date: | 2008-02-27 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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2VPB
 | | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SODIUM ION, ... | | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | | Deposit date: | 2008-02-27 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
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3ZPV
 | | Crystal structure of Drosophila Pygo PHD finger in complex with Legless HD1 domain | | Descriptor: | PROTEIN BCL9 HOMOLOG, PROTEIN PYGOPUS, ZINC ION | | Authors: | Miller, T.C.R, Mieszczanek, J, Sanchez-Barrena, M.J, Rutherford, T.J, Fiedler, M, Bienz, M. | | Deposit date: | 2013-03-02 | | Release date: | 2013-10-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Evolutionary Adaptation of the Fly Pygo Phd Finger Towards Recognizing Histone H3 Tail Methylated at Arginine 2
Structure, 21, 2013
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3SL9
 | | X-ray structure of Beta catenin in complex with Bcl9 | | Descriptor: | 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ... | | Authors: | Gupta, D, Bienz, M. | | Deposit date: | 2011-06-24 | | Release date: | 2012-02-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
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3SLA
 | | X-ray structure of first four repeats of human beta-catenin | | Descriptor: | Catenin beta-1, GLYCEROL, SODIUM ION | | Authors: | Gupta, D, Bienz, M. | | Deposit date: | 2011-06-24 | | Release date: | 2012-02-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
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2XB1
 | | Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ... | | Authors: | Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M. | | Deposit date: | 2010-04-01 | | Release date: | 2010-07-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor.
J.Mol.Biol., 401, 2010
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