1IIY
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2EZN
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2EZM
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2Y1S
| Microvirin lectin | Descriptor: | Mannan-binding lectin | Authors: | Bewley, C.A, Hussan, S. | Deposit date: | 2010-12-10 | Release date: | 2011-04-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity. J. Biol. Chem., 286, 2011
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2RLL
| CCR5 Nt(7-15) | Descriptor: | 9-mer from C-C chemokine receptor type 5 | Authors: | Bewley, C.A, Lam, S.N. | Deposit date: | 2007-07-21 | Release date: | 2007-09-25 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4 Science, 317, 2007
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7MGV
| Chryseobacterium gregarium RiPP-associated ATP-grasp ligase in complex with ADP, and a leader and core peptide | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CdnA3 Core peptide, CdnA3 Leader peptide, ... | Authors: | Bewley, C.A, Zhao, G, Kosek, D, Dyda, F. | Deposit date: | 2021-04-13 | Release date: | 2021-06-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Structural Basis for a Dual Function ATP Grasp Ligase That Installs Single and Bicyclic omega-Ester Macrocycles in a New Multicore RiPP Natural Product. J.Am.Chem.Soc., 143, 2021
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2YHH
| Microvirin:mannobiose complex | Descriptor: | MANNAN-BINDING LECTIN, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | Authors: | Hussan, S, Bewley, C.A, Clore, G.M, Gustchina, E, Ghirlando, R. | Deposit date: | 2011-05-02 | Release date: | 2011-06-15 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Monovalent Lectin Microvirin in Complex with Man(Alpha)(1-2)Man Provides a Basis for Anti-HIV Activity with Low Toxicity. J.Biol.Chem., 286, 2011
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1J4V
| CYANOVIRIN-N | Descriptor: | CYANOVIRIN-N | Authors: | Clore, G.M, Bewley, C.A. | Deposit date: | 2001-11-21 | Release date: | 2002-03-06 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Using conjoined rigid body/torsion angle simulated annealing to determine the relative orientation of covalently linked protein domains from dipolar couplings. J.Magn.Reson., 154, 2002
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7RIB
| Griffithsin mutant Y28F/Y68F/Y110F | Descriptor: | Griffithsin, SULFATE ION, alpha-D-mannopyranose | Authors: | Zhao, G, Sun, J, Bewley, C.A. | Deposit date: | 2021-07-19 | Release date: | 2022-05-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17, 2022
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7RIC
| Griffithsin variant Y28W/Y68W/Y110W | Descriptor: | Griffithsin | Authors: | Zhao, G, Sun, J, Bewley, C.A. | Deposit date: | 2021-07-19 | Release date: | 2022-05-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17, 2022
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7RIA
| Griffithsin variant Y28A/Y68A/Y110A | Descriptor: | Griffithsin, SULFATE ION, alpha-D-mannopyranose | Authors: | Zhao, G, Sun, J, Bewley, C.A. | Deposit date: | 2021-07-19 | Release date: | 2022-05-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17, 2022
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7RID
| Griffithsin variant Y28A | Descriptor: | Griffithsin | Authors: | Zhao, G, Sun, J, Bewley, C.A. | Deposit date: | 2021-07-19 | Release date: | 2022-05-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17, 2022
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1ZHS
| Crystal structure of MVL bound to Man3GlcNAc2 | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Williams, D.C, Lee, J.Y, Cai, M, Bewley, C.A, Clore, G.M. | Deposit date: | 2005-04-26 | Release date: | 2005-06-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of the HIV-1 Inhibitory Cyanobacterial Protein MVL Free and Bound to Man3GlcNAc2: STRUCTURAL BASIS FOR SPECIFICITY AND HIGH-AFFINITY BINDING TO THE CORE PENTASACCHARIDE FROM N-LINKED OLIGOMANNOSIDE. J.Biol.Chem., 280, 2005
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1ZHQ
| Crystal structure of apo MVL | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, mannan-binding lectin | Authors: | Williams, D.C, Lee, J.Y, Cai, M, Bewley, C.A, Clore, G.M. | Deposit date: | 2005-04-26 | Release date: | 2005-06-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structures of the HIV-1 Inhibitory Cyanobacterial Protein MVL Free and Bound to Man3GlcNAc2: STRUCTURAL BASIS FOR SPECIFICITY AND HIGH-AFFINITY BINDING TO THE CORE PENTASACCHARIDE FROM N-LINKED OLIGOMANNOSIDE. J.Biol.Chem., 280, 2005
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6BF4
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7RKG
| Griffithsin mutant Y28W | Descriptor: | Griffithsin, alpha-D-mannopyranose | Authors: | Zhao, G, Sun, J, Bewley, C. | Deposit date: | 2021-07-22 | Release date: | 2022-05-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17, 2022
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4DQO
| Crystal Structure of PG16 Fab in Complex with V1V2 Region from HIV-1 strain ZM109 | Descriptor: | 1FD6-V1V2 scaffold ZM109 HIV-1 strain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG16 Fab Heavy Chain, ... | Authors: | Pancera, M, McLellan, J.S, Kwong, P.D. | Deposit date: | 2012-02-16 | Release date: | 2013-03-06 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.438 Å) | Cite: | Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16. Nat.Struct.Mol.Biol., 20, 2013
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5FYL
| Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 ANTIBODY FAB HEAVY CHAIN, ... | Authors: | Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D. | Deposit date: | 2016-03-08 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G Cell(Cambridge,Mass.), 165, 2016
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5FYJ
| Crystal Structure at 3.4 A Resolution of Fully Glycosylated HIV-1 Clade G X1193.c1 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D. | Deposit date: | 2016-03-08 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G Cell(Cambridge,Mass.), 165, 2016
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5FYK
| Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade B JR-FL SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22, ... | Authors: | Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D. | Deposit date: | 2016-03-08 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.107 Å) | Cite: | Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G Cell(Cambridge,Mass.), 165, 2016
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3MAC
| crystal structure of GP41-derived protein complexed with fab 8062 | Descriptor: | Fab8062, Transmembrane glycoprotein | Authors: | Li, M, Gustchina, E, Louis, J, Gustchina, A, Wlodawer, A, Clore, M. | Deposit date: | 2010-03-23 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41. Plos Pathog., 6, 2010
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3MA9
| Crystal structure of gp41 derived protein complexed with fab 8066 | Descriptor: | Fab8066 FAB ANTIBODY FRAGMENT, Heavy Chain, Light Chain, ... | Authors: | Li, M, Gustchina, E, Louis, J, Gustchina, A, Wlodawer, A, Clore, M. | Deposit date: | 2010-03-23 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41. Plos Pathog., 6, 2010
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3RY8
| Structural basis for norovirus inhibition and fucose mimicry by citrate | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Capsid protein | Authors: | Hansman, G.S, McLellan, J.S, Kwong, P.D. | Deposit date: | 2011-05-11 | Release date: | 2011-11-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for norovirus inhibition and fucose mimicry by citrate. J.Virol., 86, 2012
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2QAD
| Structure of tyrosine-sulfated 412d antibody complexed with HIV-1 YU2 gp120 and CD4 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Huang, C.-C, Tang, M, Robinson, J, Wyatt, R, Kwong, P.D. | Deposit date: | 2007-06-14 | Release date: | 2007-09-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4 Science, 317, 2007
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3EZM
| CYANOVIRIN-N | Descriptor: | PROTEIN (CYANOVIRIN-N) | Authors: | Yang, F, Wlodawer, A. | Deposit date: | 1998-12-15 | Release date: | 1998-12-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping. J.Mol.Biol., 288, 1999
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