6T9E
| Crystal structure of a bispecific DutaFab in complex with human PDGF | Descriptor: | DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | Deposit date: | 2019-10-28 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.989 Å) | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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6T9D
| Crystal structure of a bispecific DutaFab in complex with human VEGF121 | Descriptor: | VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | Deposit date: | 2019-10-28 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.905 Å) | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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7ZW0
| FAP-80S Complex - Rotated state | Descriptor: | 18S ribosomal RNA (RDN18-1), 25S ribosomal RNA (RDN25-1), 40S ribosomal protein S0-A, ... | Authors: | Ikeuchi, K, Buschauer, R, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2022-05-17 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover. Mol.Cell, 82, 2022
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7ZPQ
| Structure of the RQT-bound 80S ribosome from S. cerevisiae (C1) | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | Deposit date: | 2022-04-28 | Release date: | 2023-02-22 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
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4V7E
| Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ... | Authors: | Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | Deposit date: | 2013-11-22 | Release date: | 2014-07-09 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion. Nature, 506, 2014
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7QH4
| Structure of the B. subtilis disome - collided 70S ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R. | Deposit date: | 2021-12-10 | Release date: | 2022-03-16 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (5.45 Å) | Cite: | Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria. Nature, 603, 2022
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7QGH
| Structure of the E. coli disome - collided 70S ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R. | Deposit date: | 2021-12-08 | Release date: | 2022-03-16 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (4.48 Å) | Cite: | Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria. Nature, 603, 2022
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7QGN
| Structure of the SmrB-bound E. coli disome - stalled 70S ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R. | Deposit date: | 2021-12-09 | Release date: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria. Nature, 603, 2022
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7QGR
| Structure of the SmrB-bound E. coli disome - collided 70S ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R. | Deposit date: | 2021-12-09 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria. Nature, 603, 2022
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4V6I
| Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ... | Authors: | Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | Deposit date: | 2010-10-12 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (8.8 Å) | Cite: | Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution. Proc.Natl.Acad.Sci.USA, 107, 2010
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7ZQ6
| 70S E. coli ribosome with truncated uL23 and uL24 loops and a stalled filamin domain 5 nascent chain | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | Deposit date: | 2022-04-29 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
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7ZQ5
| 70S E. coli ribosome with truncated uL23 and uL24 loops | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | Deposit date: | 2022-04-29 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
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1YSH
| Localization and dynamic behavior of ribosomal protein L30e | Descriptor: | 40S RIBOSOMAL PROTEIN S13, RNA (101-MER), RNA (28-MER), ... | Authors: | Halic, M, Becker, T, Frank, J, Spahn, C.M, Beckmann, R. | Deposit date: | 2005-02-08 | Release date: | 2005-07-05 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Localization and dynamic behavior of ribosomal protein L30e Nat.Struct.Mol.Biol., 12, 2005
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7QVP
| Human collided disome (di-ribosome) stalled on XBP1 mRNA | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Denk, T.G, Tesina, P, Beckmann, R. | Deposit date: | 2022-01-22 | Release date: | 2022-10-12 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation. Nat Commun, 13, 2022
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1G61
| CRYSTAL STRUCTURE OF M.JANNASCHII EIF6 | Descriptor: | TRANSLATION INITIATION FACTOR 6 | Authors: | Groft, C.M, Beckmann, R, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2000-11-02 | Release date: | 2000-11-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal structures of ribosome anti-association factor IF6. Nat.Struct.Biol., 7, 2000
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1G62
| CRYSTAL STRUCTURE OF S.CEREVISIAE EIF6 | Descriptor: | RIBOSOME ANTI-ASSOCIATION FACTOR EIF6 | Authors: | Groft, C.M, Beckmann, R, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2000-11-02 | Release date: | 2000-11-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of ribosome anti-association factor IF6. Nat.Struct.Biol., 7, 2000
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4V4B
| Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ... | Authors: | Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J. | Deposit date: | 2004-01-06 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (11.7 Å) | Cite: | Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. Embo J., 23, 2004
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3OC3
| Crystal structure of the Mot1 N-terminal domain in complex with TBP | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HELICASE MOT1, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1) | Authors: | Wollmann, P, Cui, S, Viswanathan, R, Berninghausen, O, Wells, M.N, Moldt, M, Witte, G, Butryn, A, Wendler, P, Beckmann, R, Auble, D.T, Hopfner, K.-P. | Deposit date: | 2010-08-09 | Release date: | 2011-07-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP. Nature, 475, 2011
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4V6W
| Structure of the D. melanogaster 80S ribosome | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ... | Authors: | Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R. | Deposit date: | 2013-02-27 | Release date: | 2014-07-09 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Structures of the human and Drosophila 80S ribosome. Nature, 497, 2013
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4V7F
| Arx1 pre-60S particle. | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Leidig, C, Thoms, M, Holdermann, I, Bradatsch, B, Berninghausen, O, Bange, G, Sinning, I, Hurt, E, Beckmann, R. | Deposit date: | 2013-12-10 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | 60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle. Nat Commun, 5, 2014
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4UTQ
| A structural model of the active ribosome-bound membrane protein insertase YidC | Descriptor: | ATP SYNTHASE SUBUNIT C, MEMBRANE PROTEIN INSERTASE YIDC | Authors: | Wickles, S, Singharoy, A, Andreani, J, Seemayer, S, Bischoff, L, Berninghausen, O, Soeding, J, Schulten, K, vanderSluis, E.O, Beckmann, R. | Deposit date: | 2014-07-22 | Release date: | 2014-07-30 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | A Structural Model of the Active Ribosome-Bound Membrane Protein Insertase Yidc. Elife, 3, 2014
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4UY8
| Molecular basis for the ribosome functioning as a L-tryptophan sensor - Cryo-EM structure of a TnaC stalled E.coli ribosome | Descriptor: | 50S RIBOSOMAL PROTEIN L10, 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, ... | Authors: | Bischoff, L, Berninghausen, O, Beckmann, R. | Deposit date: | 2014-08-29 | Release date: | 2014-10-29 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular Basis for the Ribosome Functioning as an L-Tryptophan Sensor. Cell Rep., 9, 2014
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4URD
| Cryo-EM map of Trigger Factor bound to a translating ribosome | Descriptor: | TRIGGER FACTOR | Authors: | Deeng, J, Chan, K.Y, van der Sluis, E, Bischoff, L, Berninghausen, O, Han, W, Gumbart, J, Schulten, K, Beatrix, B, Beckmann, R. | Deposit date: | 2014-06-27 | Release date: | 2016-01-13 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Dynamic Behavior of Trigger Factor on the Ribosome. J.Mol.Biol., 428, 2016
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4V6U
| Promiscuous behavior of proteins in archaeal ribosomes revealed by cryo-EM: implications for evolution of eukaryotic ribosomes | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10P, ... | Authors: | Armache, J.-P, Anger, A.M, Marquez, V, Frankenberg, S, Froehlich, T, Villa, E, Berninghausen, O, Thomm, M, Arnold, G.J, Beckmann, R, Wilson, D.N. | Deposit date: | 2012-08-09 | Release date: | 2014-07-09 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution. Nucleic Acids Res., 41, 2013
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4V6M
| Structure of the ribosome-SecYE complex in the membrane environment | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 16S RIBOSOMAL RNA, ... | Authors: | Frauenfeld, J, Gumbart, J, van der Sluis, E.O, Funes, S, Gartmann, M, Beatrix, B, Mielke, T, Berninghausen, O, Becker, T, Schulten, K, Beckmann, R. | Deposit date: | 2011-02-08 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | Cryo-EM structure of the ribosome-SecYE complex in the membrane environment. Nat.Struct.Mol.Biol., 18, 2011
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