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1MWJ
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BU of 1mwj by Molmil
Crystal Structure of a MUG-DNA pseudo substrate complex
Descriptor: 5'-D(*CP*GP*CP*GP*A*GP*(DU)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase
Authors:Barrett, T.E, Scharer, O, Savva, R, Brown, T, Jiricny, J, Verdine, G.L, Pearl, L.H.
Deposit date:2002-09-30
Release date:2002-10-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of a thwarted mismatch glycosylase DNA repair complex
Embo J., 18, 1999
1MUG
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BU of 1mug by Molmil
G:T/U MISMATCH-SPECIFIC DNA GLYCOSYLASE FROM E.COLI
Descriptor: PROTEIN (G:T/U SPECIFIC DNA GLYCOSYLASE), SULFATE ION
Authors:Barrett, T.E, Savva, R, Panayotou, G, Brown, T, Barlow, T, Jiricny, J, Pearl, L.H.
Deposit date:1998-07-10
Release date:1998-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions.
Cell(Cambridge,Mass.), 92, 1998
1MTL
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BU of 1mtl by Molmil
Non-productive MUG-DNA complex
Descriptor: 5'-D(*CP*GP*CP*GP*AP*GP*(AAB)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase
Authors:Barrett, T.E, Savva, R, Barlow, T, Brown, T, Jiricny, J, Pearl, L.H.
Deposit date:2002-09-21
Release date:2002-09-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a DNA base-excision product resembling a cisplatin inter-strand adduct.
Nat.Struct.Biol., 5, 1998
1MWI
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BU of 1mwi by Molmil
Crystal structure of a MUG-DNA product complex
Descriptor: 5'-D(*CP*GP*CP*GP*AP*GP*(AAB)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase
Authors:Barrett, T.E, Savva, R, Panayotou, G, Brown, T, Barlow, T, Jiricny, J, Pearl, L.H.
Deposit date:2002-09-30
Release date:2002-10-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions.
Cell(Cambridge,Mass.), 92, 1998
7PDJ
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BU of 7pdj by Molmil
R12E vFLIP mutant
Descriptor: FLICE inhibitory protein
Authors:Barrett, T.E.
Deposit date:2021-08-05
Release date:2022-05-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Mechanistic insights into the activation of the IKK kinase complex by the Kaposi's sarcoma herpes virus oncoprotein vFLIP.
J.Biol.Chem., 298, 2022
1CBG
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BU of 1cbg by Molmil
THE CRYSTAL STRUCTURE OF A CYANOGENIC BETA-GLUCOSIDASE FROM WHITE CLOVER (TRIFOLIUM REPENS L.), A FAMILY 1 GLYCOSYL-HYDROLASE
Descriptor: CYANOGENIC BETA-GLUCOSIDASE
Authors:Barrett, T.E, Suresh, C.G, Tolley, S.P, Hughes, M.A.
Deposit date:1995-07-31
Release date:1995-10-15
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The crystal structure of a cyanogenic beta-glucosidase from white clover, a family 1 glycosyl hydrolase.
Structure, 3, 1995
2D7D
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BU of 2d7d by Molmil
Structural insights into the cryptic DNA dependent ATP-ase activity of UvrB
Descriptor: 40-mer from UvrABC system protein B, 5'-D(P*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Barrett, T.E.
Deposit date:2005-11-18
Release date:2006-05-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into the cryptic DNA-dependent ATPase activity of UvrB
J.Mol.Biol., 357, 2006
5HSW
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BU of 5hsw by Molmil
KSHV SOX RNA complex
Descriptor: ACETATE ION, ORF 37, RNA (5'-R(P*UP*CP*UP*UP*GP*AP*AP*GP*CP*AP*GP*CP*UP*UP*CP*CP*AP*G)-3')
Authors:Barrett, T.E.
Deposit date:2016-01-26
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing.
Nucleic Acids Res., 45, 2017
2NMV
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BU of 2nmv by Molmil
Damage detection by the UvrABC pathway: Crystal structure of UvrB bound to fluorescein-adducted DNA
Descriptor: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 5'-D(P*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Waters, T.R, Eryilmaz, J, Geddes, S, Barrett, T.E.
Deposit date:2006-10-23
Release date:2007-01-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Damage detection by the UvrABC pathway: crystal structure of UvrB bound to fluorescein-adducted DNA
Febs Lett., 580, 2006
1KCF
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BU of 1kcf by Molmil
Crystal Structure of the Yeast Mitochondrial Holliday Junction Resolvase, Ydc2
Descriptor: HYPOTHETICAL 30.2 KD PROTEIN C25G10.02 IN CHROMOSOME I, SULFATE ION
Authors:Ceschini, S, Keeley, A, McAlister, M.S.B, Oram, M, Phelan, J, Pearl, L.H, Tsaneva, I.R, Barrett, T.E.
Deposit date:2001-11-08
Release date:2001-11-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the fission yeast mitochondrial Holliday junction resolvase Ydc2.
EMBO J., 20, 2001
1KO9
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BU of 1ko9 by Molmil
Native Structure of the Human 8-oxoguanine DNA Glycosylase hOGG1
Descriptor: 8-oxoguanine DNA glycosylase, SULFATE ION
Authors:Bjoras, M, Seeberg, E, Luna, L, Pearl, L.H, Barrett, T.E.
Deposit date:2001-12-20
Release date:2002-01-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase.
J.Mol.Biol., 317, 2002
3DRU
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BU of 3dru by Molmil
Crystal Structure of Gly117Phe Alpha1-Antitrypsin
Descriptor: Alpha-1-antitrypsin
Authors:Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
Deposit date:2008-07-11
Release date:2009-03-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3DRM
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BU of 3drm by Molmil
2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin
Descriptor: Alpha-1-antitrypsin
Authors:Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
Deposit date:2008-07-11
Release date:2009-03-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3POV
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BU of 3pov by Molmil
Crystal structure of a SOX-DNA complex
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*CP*CP*TP*CP*CP*CP*AP*GP*TP*CP*GP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*CP*GP*AP*CP*TP*AP*GP*GP*AP*GP*GP*AP*TP*CP*CP*C)-3'), FORMIC ACID, ...
Authors:Bagneris, C, Barrett, T.E.
Deposit date:2010-11-23
Release date:2011-09-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a KSHV-SOX-DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoff
Nucleic Acids Res., 39, 2011
5LDE
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BU of 5lde by Molmil
Crystal structure of a vFLIP-IKKgamma stapled peptide dimer
Descriptor: Immunoglobulin G-binding protein G,Viral FLICE protein, Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, ...
Authors:Barrett, T.
Deposit date:2016-06-24
Release date:2017-10-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:IKK gamma-Mimetic Peptides Block the Resistance to Apoptosis Associated with Kaposi's Sarcoma-Associated Herpesvirus Infection.
J. Virol., 91, 2017
1QO0
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BU of 1qo0 by Molmil
Amide receptor of the amidase operon of Pseudomonas aeruginosa (AmiC) complexed with the negative regulator AmiR.
Descriptor: AMIC, AMIR, BUTYRAMIDE
Authors:Pearl, L.H, O'Hara, B.P, Roe, S.M.
Deposit date:1999-10-26
Release date:1999-12-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure and Induction Mechanism of Amic-Amir: A Ligand-Regulated Transcription Antitermination Complex
Embo J., 18, 1999
3NE4
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BU of 3ne4 by Molmil
1.8 Angstrom structure of intact native wild-type alpha-1-antitrypsin
Descriptor: Alpha-1-antitrypsin
Authors:Patschull, A.O.M, Gooptu, B, Segu, L.
Deposit date:2010-06-08
Release date:2011-12-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Therapeutic target-site variability in [alpha]1-antitrypsin characterized at high resolution
Acta Crystallogr.,Sect.F, 67, 2011

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