Author results

1HZ5
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CRYSTAL STRUCTURES OF THE B1 DOMAIN OF PROTEIN L FROM PEPTOSTREPTOCOCCUS MAGNUS, WITH A TYROSINE TO TRYPTOPHAN SUBSTITUTION
Descriptor:PROTEIN L, ZINC ION
Authors:O'Neill, J.W., Kim, D.E., Baker, D., Zhang, K.Y.J.
Deposit date:2001-01-23
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution.
Acta Crystallogr.,Sect.D, 57, 2001
1HZ6
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CRYSTAL STRUCTURES OF THE B1 DOMAIN OF PROTEIN L FROM PEPTOSTREPTOCOCCUS MAGNUS WITH A TYROSINE TO TRYPTOPHAN SUBSTITUTION
Descriptor:PROTEIN L
Authors:O'Neill, J.W., Kim, D.E., Baker, D., Zhang, K.Y.J.
Deposit date:2001-01-23
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution.
Acta Crystallogr.,Sect.D, 57, 2001
1JML
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CONVERSION OF MONOMERIC PROTEIN L TO AN OBLIGATE DIMER BY COMPUTATIONAL PROTEIN DESIGN
Descriptor:Protein L, ZINC ION
Authors:O'Neill, J.W., Kuhlman, B., Kim, D.E., Zhang, K.Y.J., Baker, D.
Deposit date:2001-07-19
Release date:2001-10-10
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conversion of monomeric protein L to an obligate dimer by computational protein design.
Proc.Natl.Acad.Sci.USA, 98, 2001
1K50
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A V49A MUTATION INDUCES 3D DOMAIN SWAPPING IN THE B1 DOMAIN OF PROTEIN L FROM PEPTOSTREPTOCOCCUS MAGNUS
Descriptor:Protein L
Authors:O'Neill, J.W., Kim, D.E., Johnsen, K., Baker, D., Zhang, K.Y.J.
Deposit date:2001-10-09
Release date:2001-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1K51
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A G55A MUTATION INDUCES 3D DOMAIN SWAPPING IN THE B1 DOMAIN OF PROTEIN L FROM PEPTOSTREPTOCOCCUS MAGNUS
Descriptor:Protein L, ZINC ION
Authors:O'Neill, J.W., Kim, D.E., Johnsen, K., Baker, D., Zhang, K.Y.J.
Deposit date:2001-10-09
Release date:2001-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1K52
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MONOMERIC PROTEIN L B1 DOMAIN WITH A K54G MUTATION
Descriptor:Protein L, ZINC ION
Authors:O'Neill, J.W., Kim, D.E., Johnsen, K., Baker, D., Zhang, K.Y.J.
Deposit date:2001-10-09
Release date:2001-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1K53
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MONOMERIC PROTEIN L B1 DOMAIN WITH A G15A MUTATION
Descriptor:Protein L, ZINC ION
Authors:O'Neill, J.W., Kim, D.E., Johnsen, K., Baker, D., Zhang, K.Y.J.
Deposit date:2001-10-09
Release date:2001-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus.
Structure, 9, 2001
1KH0
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ACCURATE COMPUTER BASE DESIGN OF A NEW BACKBONE CONFORMATION IN THE SECOND TURN OF PROTEIN L
Descriptor:protein L
Authors:O'Neill, J.W., Kuhlman, B., Kim, D.E., Zhang, K.Y., Baker, D.
Deposit date:2001-11-28
Release date:2002-01-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Accurate computer-based design of a new backbone conformation in the second turn of protein L.
J.Mol.Biol., 315, 2002
1MHX
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CRYSTAL STRUCTURES OF THE REDESIGNED PROTEIN G VARIANT NUG1
Descriptor:immunoglobulin-binding protein G
Authors:Nauli, S., Kuhlman, B., Le Trong, I., Stenkamp, R.E., Teller, D.C., Baker, D.
Deposit date:2002-08-21
Release date:2002-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2
Protein Sci., 11, 2002
1MI0
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CRYSTAL STRUCTURE OF THE REDESIGNED PROTEIN G VARIANT NUG2
Descriptor:immunoglobulin-binding protein G
Authors:Nauli, S., Kuhlman, B., Le Trong, I., Stenkamp, R.E., Teller, D.C., Baker, D.
Deposit date:2002-08-21
Release date:2002-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2
Biochemistry, 11, 2002
1MOW
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E-DREI
Descriptor:5'-D(*CP*CP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*G)-3', 5'-D(*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*GP*G)-3', chimera of homing endonuclease I-DmoI and DNA endonuclease I-CreI, ...
Authors:Chevalier, B.S., Kortemme, T., Chadsey, M.S., Baker, D., Monnat Jr., R.J., Stoddard, B.L.
Deposit date:2002-09-10
Release date:2002-11-29
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design, Activity and Structure of a Highly Specific Artificial Endonuclease
Mol.Cell, 10, 2002
1MPU
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CRYSTAL STRUCTURE OF THE FREE HUMAN NKG2D IMMUNORECEPTOR
Descriptor:NKG2-D type II integral membrane protein, PHOSPHATE ION
Authors:McFarland, B.J., Kortemme, T., Baker, D., Strong, R.K.
Deposit date:2002-09-12
Release date:2003-04-15
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Symmetry Recognizing Asymmetry: Analysis of the Interactions between the C-Type Lectin-like Immunoreceptor NKG2D and MHC Class I-like Ligands
Structure, 11, 2003
1PVH
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CRYSTAL STRUCTURE OF LEUKEMIA INHIBITORY FACTOR IN COMPLEX WITH GP130
Descriptor:Interleukin-6 receptor beta chain, Leukemia inhibitory factor, IODIDE ION
Authors:Boulanger, M.J., Bankovich, A.J., Kortemme, T., Baker, D., Garcia, K.C.
Deposit date:2003-06-27
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130.
Mol.Cell, 12, 2003
1QYS
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CRYSTAL STRUCTURE OF TOP7: A COMPUTATIONALLY DESIGNED PROTEIN WITH A NOVEL FOLD
Descriptor:TOP7
Authors:Kuhlman, B., Dantas, G., Ireton, G.C., Varani, G., Stoddard, B.L., Baker, D.
Deposit date:2003-09-11
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
Science, 302, 2003
1TVG
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X-RAY STRUCTURE OF HUMAN PP25 GENE PRODUCT, HSPC034. NORTHEAST STRUCTURAL GENOMICS TARGET HR1958.
Descriptor:LOC51668 protein, CALCIUM ION, SAMARIUM (III) ION
Authors:Kuzin, A.P., Vorobiev, S.M., Lee, I., Acton, T.B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-06-29
Release date:2004-11-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study.
Proteins, 75, 2009
1UJZ
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CRYSTAL STRUCTURE OF THE E7_C/IM7_C COMPLEX; A COMPUTATIONALLY DESIGNED INTERFACE BETWEEN THE COLICIN E7 DNASE AND THE IM7 IMMUNITY PROTEIN
Descriptor:Designed Colicin E7 immunity protein, Designed Colicin E7 DNase
Authors:Kortemme, T., Joachimiak, L.A., Bullock, A.N., Schuler, A.D., Stoddard, B.L., Baker, D.
Deposit date:2003-08-13
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Computational redesign of protein-protein interaction specificity
NAT.STRUCT.MOL.BIOL., 11, 2004
1VJQ
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DESIGNED PROTEIN BASED ON BACKBONE CONFORMATION OF PROCARBOXYPEPTIDASE-A (1AYE) WITH SIDECHAINS CHOSEN FOR MAXIMAL PREDICTED STABILITY.
Descriptor:designed protein
Authors:Merritt, E.A., Baker, D., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-03-19
Release date:2004-03-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability.
To be Published
1XPW
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SOLUTION NMR STRUCTURE OF HUMAN PROTEIN HSPCO34. NORTHEAST STRUCTURAL GENOMICS TARGET HR1958
Descriptor:LOC51668 protein
Authors:Ramelot, T.A., Xiao, R., Ma, L.C., Acton, T.B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-10-09
Release date:2004-11-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study.
Proteins, 75, 2009
1YSB
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YEAST CYTOSINE DEAMINASE TRIPLE MUTANT
Descriptor:Cytosine deaminase, ZINC ION, CALCIUM ION
Authors:Korkegian, A., Black, M.E., Baker, D., Stoddard, B.L.
Deposit date:2005-02-08
Release date:2005-05-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Computational thermostabilization of an enzyme.
Science, 308, 2005
1YSD
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YEAST CYTOSINE DEAMINASE DOUBLE MUTANT
Descriptor:Cytosine deaminase, ZINC ION, CALCIUM ION
Authors:Korkegian, A., Black, M.E., Baker, D., Stoddard, B.L.
Deposit date:2005-02-08
Release date:2005-05-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Computational thermostabilization of an enzyme.
Science, 308, 2005
2A0M
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ARGINASE SUPERFAMILY PROTEIN FROM TRYPANOSOMA CRUZI
Descriptor:ARGINASE SUPERFAMILY PROTEIN, CHLORIDE ION
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-16
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Structural genomics of pathogenic protozoa: an overview.
Methods Mol.Biol., 426, 2008
2A3J
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STRUCTURE OF URNDESIGN, A COMPLETE COMPUTATIONAL REDESIGN OF HUMAN U1A PROTEIN
Descriptor:U1 small nuclear ribonucleoprotein A
Authors:Varani, G., Dobson, N., Dantas, G., Baker, D.
Deposit date:2005-06-24
Release date:2006-06-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High-Resolution Structural Validation of the Computational Redesign of Human U1A Protein
Structure, 14, 2006
2AR1
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STRUCTURE OF HYPOTHETICAL PROTEIN FROM LEISHMANIA MAJOR
Descriptor:hypothetical protein, GLYCEROL
Authors:Arakaki, T.L., Merritt, E.A., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-08-18
Release date:2005-08-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major.
Acta Crystallogr.,Sect.F, 62, 2006
2ERH
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CRYSTAL STRUCTURE OF THE E7_G/IM7_G COMPLEX; A DESIGNED INTERFACE BETWEEN THE COLICIN E7 DNASE AND THE IM7 IMMUNITY PROTEIN
Descriptor:Colicin E7 immunity protein, Colicin E7
Authors:Joachimiak, L.A., Kortemme, T., Stoddard, B.L., Baker, D.
Deposit date:2005-10-24
Release date:2006-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational Design of a New Hydrogen Bond Network and at Least a 300-fold Specificity Switch at a Protein-Protein Interface.
J.Mol.Biol., 361, 2006
2FLD
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I-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY
Descriptor:5'-D(*GP*CP*AP*GP*AP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*TP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*AP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*TP*TP*CP*TP*GP*C)-3', DNA ENDONUCLEASE I-MSOI, ...
Authors:Ashworth, J., Duarte, C.M., Havranek, J.J., Sussman, D., Monnat, R.J., Stoddard, B.L., Baker, D.
Deposit date:2006-01-05
Release date:2006-06-06
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational redesign of endonuclease DNA binding and cleavage specificity.
Nature, 441, 2006